A World-Leading Centre for Predictive in vitro Model Research, Training and Translation
The Queen Mary Centre for Predictive in vitro Models (CPM) provides a beacon of multidisciplinary research, training, and translation focusing on the development and use of predictive in vitro models. This incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, Non Animal Methods (NAMs), and other types of in vitro model.
With approximately 100 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership an extensive list of partners and industry affiliates.
Queen Mary provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.
Events
| Mon 9 - Fri 13 Jun 2025 | Microphysiological Systems (MPS) World Summit 2025 |
 Mon 9 Jun 2025 | London gastroIntestinal Organoid Network (LION) |
| Mon 16 - Tue 17 Jun 2025 | 3rd Workshop on the European Commission roadmap towards phasing out animal testing for chemical safety assessments |
| Wed 18 - Fri 20 Jun 2025 | Tissue & Cell Engineering Society Conference 2025 |
| Fri 27 Jun 2025 10:00 - 16:00 | The UK Microsystems Network Launch  |
| Sun 28 Sep - Wed 1 Oct 2025 | Bioengineered Tissue Systems & Models |
Recent Publications
- Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems
Hopkins T, Midha S, Grossemy S, Screen HRC, Wann AKT and Knight MM
Journal of Tissue Engineering vol. 16
18-04-2025 - Replicating Dynamic Immune Responses at Single‐Cell Resolution within a Microfluidic Human Skin Equivalent
Hindle SA, Brook HB, Chrysanthou A, Chambers ES, Caley MP and Connelly JT
Advanced Science, Wiley vol. 12 (10)
21-01-2025 - Role of Myofibroblasts in the Repair of Iatrogenic Preterm Membranes Subjected to Mechanical Stimulation
Costa E, Thrasivoulou C, Becker DL, Deprest J, David AL and Chowdhury TT
Prenatal Diagnosis, Wiley vol. 45 (1), 102-112.
04-12-2024
Recent Grants
- The influence of a complex in vitro tumour microenvironment on cancer stem cells metastasis
Adrian Biddle and Ana Caetano
£547,066 National Centre for the Replacement, Refinement and Reduction of Animals in Research
01-05-2025 - 30-04-2028 - Investigating perfused inflammatory and immune responses in 3D barrier-immune models for atopic dermatitis
John Connelly
£196,508 GlaxoSmithKline UK Ltd
01-02-2025 - 31-01-2026 - Investigating the roles of endogenous retro viruses as regulators of gene expression in the endometrial epithelium
Miguel Branco
£731,019 BBSRC Biotechnology and Biological Sciences Research Council
01-02-2025 - 31-01-2028