• Different organ-chips available at the CPM
  • Members of the CPM at MPS conference
  • Micro-patterned <em>in vitro</em> model of keratinocyte colonies
  • Ciliated cells inside an airway organ-chip from Emulate

A World-Leading Centre for Predictive in vitro Model Research, Training and Translation

Our vision is to work with key stakeholders to translate innovative in vitro models for highest quality discovery science and to accelerate delivery of safe and effective therapeutics for the benefit of wider society.

Research with the Centre incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, Non Animal Methods (NAMs), and other types of in vitro model.

With approximately 100 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership an extensive list of partners and industry affiliates.

Queen Mary provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.

Events

News

Recent Publications

  • Three-dimensional numerical analysis of wall stress induced by asymmetric oscillation of microbubble trains inside micro-vessels
    Ri J, Pang N, Bai S, Xu J, Xu L, Ri S, Yao Y, Greenwald SE
    Physics of Fluids, Aip Publishing vol. 35 (1) 
    01-01-2023
  • Estimation of central pulse wave velocity from radial pulse wave analysis
    Yao Y, Zhou S, Alastruey J, Hao L, Greenwald SE, Zhang Y, Xu L, Xu L et al.
    Computer Methods and Programs in Biomedicine, Elsevier vol. 219 
    27-03-2022
  • Improving the accuracy and robustness of carotid-femoral pulse wave velocity measurement using a simplified tube-load model
    Xu L, Zhou S, Wang L, Yao Y, Hao L, Qi L, Yao Y, Han H et al.
    Scientific Reports, Springer Nature vol. 12 (1) 
    25-03-2022

View more publications »

Recent Grants

  • Determining the mechanisms of human tau pathology clearance to inform therapeutic development
    Cara Croft
    £549,747 Alzheimer's Society
    01-08-2025 - 31-07-2030
  • Human Tendon-CHIP: Novel In Vitro Predictive Models To Explore Tendinopathy
    Hazel Screen, Xavier Griffin and John Connelly
    £668,842 Medical Research Council
    01-08-2025 - 31-07-2028
  • Investigating the roles of endogenous retro viruses as regulators of gene expression in the endometrial epithelium
    Miguel Branco
    £731,019 Biotechnology and Biological Sciences Research Council
    28-07-2025 - 27-07-2028

View more grants »