A World-Leading Centre for Predictive in vitro Model Research, Training and Translation
Research with the Centre incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, Non Animal Methods (NAMs), and other types of in vitro model.
With approximately 100 academic staff across the Faculty of Science and Engineering and the Faculty of Medicine and Dentistry, Queen Mary's Centre for Predictive in vitro Models is leading development and use of these complex in vitro models in partnership an extensive list of partners and industry affiliates.
Queen Mary provide leadership in this field hosting the annual UK symposium and engaging with Government, policy makers, funders, industry and other stake holders to support development and adoption of this transformative technology.
Events
 Mon 1 Sep 2025 | NC3RS Technology Partn3Ring |
| Sun 28 Sep - Wed 1 Oct 2025 | Bioengineered Tissue Systems & Models |
| Wed 1 Oct 2025 13:00 - 17:30 | 2025 UK Organ-on-a-Chip Symposium |
| Thu 4 Dec 2025 11:00 - 18:00 | Christmas Research Celebration - Queen Mary & WORD+ World Organoid and Organ-Chip Community |
Recent Publications
- Development of human skin equivalents with inducible ceramide depletion for in vitro modelling of lipid impairment
Dina DO, Maiellaro M, Camera E and Connelly JT
Jid Innovations, Elsevier
01-05-2025 - Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems
Hopkins T, Midha S, Grossemy S, Screen HRC, Wann AKT and Knight MM
Journal of Tissue Engineering vol. 16
18-04-2025 - Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Henriques Schneider A, Cecconello C, Bu W, Imbert PRC, Wright TD, Russo S, Blacksell IA, Koenis DS, Dalli J, Lupisella JA, Wurtz NR, Garcia RA, Cooper D, Norling LV and Perretti M
Embo Molecular Medicine, Springer Nature, 1-31.
03-04-2025
Recent Grants
- Human Tendon-CHIP: Novel In Vitro Predictive Models To Explore Tendinopathy
Hazel Screen, Xavier Griffin and John Connelly
£668,842 Medical Research Council
01-08-2025 - 31-07-2028 - (uPSCale) Scaling up iPSC Expansion and Differentiation using Recombinant Bioemulsions
Julien Gautrot
£118,175 EU Commission - Horizon Europe
01-05-2025 - 31-10-2026 - The influence of a complex in vitro tumour microenvironment on cancer stem cells metastasis
Adrian Biddle and Ana Caetano
£547,066 National Centre for the Replacement, Refinement and Reduction of Animals in Research
01-05-2025 - 30-04-2028