Research Themes

The Centre for Predictive in vitro Models at Queen Mary University of London provides a virtual centre for internationally leading research associated with the development and use of sophisticated in vitro models. These includes models for a broad range of tissues/organs and different pathologies as well as research into the underpinning bioengineering that is essential for development of these models (see table and keywords wordcloud below). Within these areas, research and development activity across the CPM is focussed under the following themes: Skin; Musculoskeletal; Cardiovascular: Neuronal; Cancer: Infectious Diseases and Inflammation; and Underpinning Bioengineering

Tissue/Organ

Intestine
Liver
Kidney
Skin
Cartilage
Synovium
Tendon
Bone
Blood vessels & Heart
Blood-Brain barrier
Nerve
Placenta

Pathologies

Ageing
Inflammation
Arthritis
Cancer (prostate, breast, ovarian, pancreatic, bladder)
Cardiovascular disease
Brain / Spinal Cord Injury
Obesity / Metabolic disorders
Maternal health
Peridontal disease
Fibrosis
COVID-19

Bioengineering

Biomaterials
Mechanobiology
Organ-on-a-chip
3D bioprinting
Machine learning / AI
Sensors
Computational Modelling
Microfluidics
Micro/Nano patterning
Stem cell manipulation
Extracellular Matrix
Implant testing

TissUse Organ-chip platform