Research Publications
The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.
2024
Allen O, Knight MM and Verbruggen SW (2024). Air Pollution and Osteoporosis. Springer Science and Business Media LLC Current Osteoporosis Reports
Ogrodnik M, Carlos Acosta J, Adams PD, d'Adda di Fagagna F, Baker DJ, Bishop CL, Chandra T, Collado M, Gil J, Gorgoulis V, Gruber F, Hara E, Jansen-Dürr P, Jurk D, Khosla S, Kirkland JL, Krizhanovsky V, Minamino T, Niedernhofer LJ, Passos JF, Ring NAR, Redl H, Robbins PD, Rodier F, Scharffetter-Kochanek K, Sedivy JM, Sikora E, Witwer K, von Zglinicki T and Yun MH (2024). Guidelines for minimal information on cellular senescence experimentation in vivo. Elsevier Cell vol. 187, (16) 4150-4175.
Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Manchanda R, Annibaldi A, Hopkins S, Garrobo-Calleja I, Gautrot J and Balkwill FR (2024). Human 3D Ovarian Cancer Models Reveal Malignant Cell-Intrinsic and -Extrinsic Factors That Influence CAR T-cell Activity. Cancer Res vol. 84, (15) 2432-2449.
Lujan C, Tyler EJ, Ecker S, Webster AP, Stead ER, Martinez-Miguel VE, Milligan D, Garbe JC, Stampfer MR, Beck S, Lowe R, Bishop CL and Bjedov I (2024). An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo. Springer Nature Genome Medicine vol. 16, (1)
Liu Y, Okesola BO, de la Peña DO, Li W, Lin M, Trabulo S, Tatari M, Lawlor RT, Scarpa A, Wang W, Knight M, Loessner D, Heeschen C, Mata A and Pearce OMT (2024). A Self‐Assembled 3D Model Demonstrates How Stiffness Educates Tumor Cell Phenotypes and Therapy Resistance in Pancreatic Cancer. Wiley Advanced Healthcare Materials vol. 13, (17)
Fromager B, Cambedouzou J, Marhuenda E, Iskratsch T, Pinault M, Bakalara N and Cornu D (2024). Tunable electrospun scaffolds of polyacrylonitrile loaded with carbon nanotubes: from synthesis to biological applications. Wiley ChemBioChem vol. 25, (7)
Swiatlowska P, Tipping W, Marhuenda E, Severi P, Fomin V, Yang Z, Xiao Q, Graham D, Shanahan C and Iskratsch T (2024). Hypertensive Pressure Mechanosensing Alone Triggers Lipid Droplet Accumulation and Transdifferentiation of Vascular Smooth Muscle Cells to Foam Cells (Adv. Sci. 9/2024). Wiley Advanced Science vol. 11, (9)
Di Cio S, Marhuenda E, Haddrick M and Gautrot JE (2024). Vascularised cardiac spheroids-on-a-chip for testing the toxicity of therapeutics. Springer Nature Scientific Reports vol. 14, (1)
Scemama A, Lunetto S, Tailor A, Di Cio S, Dibble M, Gautrot J and Biddle A (2024). Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis. F1000Research F1000Research vol. 12,
2023
Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR and Knight MM (2023). A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells. Wiley Advanced Science vol. 11, (2) 2305842-2305842.
Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L, Lunetto S, Varela A, Orgaz JL, Vilardell F, Olsina JJ, Matias-Guiu X, Sarker D, Biddle A, Balkwill FR, Eyles J, Wilkinson RW, Kocher HM, Calvo F, Wells CM and Sanz-Moreno V (2023). CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells. American Association for the Advancement of Science (AAAS) Science Advances vol. 9, (42)
Thompson CL, Hopkins T, Bevan C, Screen HRC, Wright KT and Knight MM (2023). Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. IOP Publishing Biomedical Materials vol. 18, (6)
Costa E, Thrasivoulou C, Becker DL, Deprest JA, David AL and Chowdhury TT (2023). Cx43 regulates mechanotransduction mechanisms in human preterm amniotic membrane defects. Wiley Prenatal Diagnosis
Rulten SL, Grose RP, Gatz SA, Jones JL and Cameron AJM (2023). The Future of Precision Oncology. MDPI International Journal of Molecular Sciences vol. 24, (16)
Pensalfini M, Golde T, Trepat X and Arroyo M (2023). Nonaffine Mechanics of Entangled Networks Inspired by Intermediate Filaments. American Physical Society (APS) Physical Review Letters vol. 131, (5)
Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J and Li Y (2023). Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity. American Chemical Society (ACS) ACS Applied Materials & Interfaces vol. 15, (29) 35741-35749.
Gibson SV, Madzharova E, Tan AC, Allen MD, Keller UAD, Jones JL, Carter EP and Grose RP (2023). ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation. Elsevier Matrix Biology vol. 121, 74-89.
McArthur S (2023). The gut microbe‐derived methylamine TMAO protects against neuroinflammation through restraint of pro‐inflammatory glial behaviour. Wiley Alzheimer's & Dementia vol. 19, (S1)
Neri-Cruz CE, Teixeira FME and Gautrot JE (2023). A guide to functionalisation and bioconjugation strategies to surface-initiated polymer brushes. Royal Society of Chemistry Chemical Communications vol. 59, (49) 7534-7558.
Lu RX, Guo ZY, Yu P and Sui Y (2023). Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity. Cambridge University Press (CUP) Journal of Fluid Mechanics vol. 962,
Smith CJ, Chan L and Metherell LA (2023). 769 Reduced expression of PPOX, the variegate porphyria gene, causes intrinsic pathological changes to keratinocytes. Elsevier Journal of Investigative Dermatology vol. 143, (5)
Baksh RA, Pape SE, Chan LF, Aslam AA, Gulliford MC, Strydom A and Consortium G-D (2023). Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: a population-based cohort study using electronic health records. Elsevier The Lancet Public Health vol. 8, (6) e453-e462.
Scemama A, Tailor A, Di Cio S, Dibble M, Gautrot J and Biddle A (2023). Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis. Taylor and Francis F1000Research vol. 12, 439-439.
Cervantes-Salguero K, Gutiérrez Fosado YA, Megone W, Gautrot JE and Palma M (2023). Programmed Self-Assembly of DNA Nanosheets with Discrete Single-Molecule Thickness and Interfacial Mechanics: Design, Simulation, and Characterization. MDPI Molecules vol. 28, (9)
Dibble M, Di Cio’ S, Luo P, Balkwill F and Gautrot JE (2023). The impact of pericytes on the stability of microvascular networks in response to nanoparticles. Springer Nature Scientific Reports vol. 13, (1)
Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Hopkins S, Garrobo-Calleja I, Gautrot J and Balkwill F (2023). Abstract 4576: 3D in vitro models uncover malignant cell intrinsic and extrinsic mechanisms of CAR-T cell resistance in high grade serous ovarian cancer. American Association for Cancer Research (AACR) Cancer Research vol. 83, (7_Supplement) 4576-4576.
Clayton NS, Carter EP, Fearon AE, Heward JA, Fernández LR, Boughetane L, Wilkes EH, Cutillas PR and Grose RP (2023). HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction. MDPI International Journal of Molecular Sciences vol. 24, (7)
Guo Z, Lin T, Jing D, Wang W and Sui Y (2023). A method for real-time mechanical characterisation of microcapsules. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1209-1220.
Bort ET, Joseph MD, Wang Q, Carter EP, Roth NJ, Gibson J, Samadi A, Kocher HM, Simoncelli S, McCormick PJ and Grose RP (2023). Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion. eLife eLife vol. 12,
Peng L, Nadal C and Gautrot JE (2023). Growth of mesenchymal stem cells at the surface of silicone, mineral and plant-based oils. IOP Publishing Biomedical Materials vol. 18, (3)
Pensalfini M and Tepole AB (2023). Mechano-biological and bio-mechanical pathways in cutaneous wound healing. Public Library of Science (PLoS) PLOS Computational Biology vol. 19, (3)
Harley P, Paredes-Redondo A, Grenci G, Viasnoff V, Lin Y-Y and Lieberam I (2023). 3D Compartmentalised Human Pluripotent Stem Cell–derived Neuromuscular Co-cultures. Bio-protocol vol. 13, (5) e4624-e4624.
Gibson SV, Tomas Bort E, Rodríguez-Fernández L, Allen MD, Gomm JJ, Goulding I, auf dem Keller U, Agnoletto A, Brisken C, Peck B, Cameron AJ, Marshall JF, Jones JL, Carter EP and Grose RP (2023). TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression. Springer Nature npj Breast Cancer vol. 9, (1)
Smith CJ, Williams JL, Hall C, Casas J, Caley MP, O'Toole EA, Prasad R and Metherell LA (2023). Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation. Elsevier Journal of Lipid Research vol. 64, (4)
Wang Z, Lu R, Wang W, Tian FB, Feng JJ and Sui Y (2023). A computational model for the transit of a cancer cell through a constricted microchannel. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1129-1143.
Peng L, Matellan C, Bosch‐Fortea M, Gonzalez‐Molina J, Frigerio M, Salentinig S, del Rio Hernandez A and Gautrot JE (2023). Mesenchymal Stem Cells Sense the Toughness of Nanomaterials and Interfaces. Wiley Advanced Healthcare Materials vol. 12, (13)
Gibson SV, Roozitalab RM, Allen MD, Jones JL, Carter EP and Grose RP (2023). Everybody needs good neighbours: the progressive DCIS microenvironment. Elsevier Trends in Cancer vol. 9, (4) 326-338.
Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S, Cutillas P, Mohammed H, Grose RP and Ficz G (2023). Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening. The Company of Biologists Disease Models & Mechanisms vol. 16, (2)
Nguyen KDQ, Dejean S, Nottelet B and Gautrot JE (2023). Mechanical Evaluation of Hydrogel–Elastomer Interfaces Generated through Thiol–Ene Coupling. American Chemical Society (ACS) ACS Applied Polymer Materials vol. 5, (2) 1364-1373.
Chrysanthou A, Bosch-Fortea M and Gautrot JE (2023). Co-Surfactant-Free Bioactive Protein Nanosheets for the Stabilization of Bioemulsions Enabling Adherent Cell Expansion. American Chemical Society (ACS) Biomacromolecules vol. 24, (10) 4465-4477.
Nolan J, Pearce OMT, Screen HRC, Knight MM and Verbruggen SW (2023). Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK. MDPI Cancers vol. 15, (3)
Chrysanthou A, Kanso H, Zhong W, Shang L and Gautrot JE (2023). Supercharged Protein Nanosheets for Cell Expansion on Bioemulsions. American Chemical Society (ACS) ACS Applied Materials & Interfaces vol. 15, (2) 2760-2770.
Stachulski AV, Knausenberger TB-A, Shah SN, Hoyles L and McArthur S (2023). A host-gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood-brain barrier integrity in vivo. Tissue Barriers vol. 11, (1) 2073175-2073175.
Ri J, Pang N, Bai S, Xu J, Xu L, Ri S, Yao Y and Greenwald SE (2023). Three-dimensional numerical analysis of wall stress induced by asymmetric oscillation of microbubble trains inside micro-vessels. AIP Publishing Physics of Fluids vol. 35, (1)
Arain Z, Iliodromiti S, Slabaugh G, David AL and Chowdhury TT (2023). Machine learning and disease prediction in obstetrics. Elsevier Current Research in Physiology vol. 6,
Azhar Z, Grose RP, Raza A and Raza Z (2023). In silico targeting of colony-stimulating factor-1 receptor: delineating immunotherapy in cancer. Open Exploration Publishing Exploration of Targeted Anti-tumor Therapy vol. 4, (4) 727-742.
2022
Jacques R, Zhou B, Marhuenda E, Gorecki J, Das A, Iskratsch T and Krause S (2022). Photoelectrochemical imaging of single cardiomyocytes and monitoring of their action potentials through contact force manipulation of organoids. Elsevier Biosensors and Bioelectronics
Bishop C (2022). Current Understanding of the Role of Senescent Melanocytes in Skin Ageing. MDPI Biomedicines vol. 10, (12) 3111-3111.
Smith CJ, Williams JL, Hall C, Caley MP, O’Toole EA, Prasad R and Metherell LA (2022). 181 Sphingosine 1-phosphate lyase insufficiency induced ichthyosis is due to sphingolipid imbalance, increased differentiation, and aberrant intercellular junctions. Elsevier Journal of Investigative Dermatology vol. 142, (12)
Iskratsch T, Hawkes W, Marhuenda E, Reynolds P, O'Neill C, PANDEY P, Wilson D, FREELEY M, HUANG D, Junquiang H, Gondarenko S, Hone J, Gadegaard N and Palma M (2022). Regulation of Cardiomyocyte Adhesion and
Mechanosignalling Through Distinct Nanoscale Behaviour of
Integrin Ligands Mimicking Healthy or Fibrotic ECM. The Royal Society Philosophical Transactions of the Royal Society B: Biological Sciences
Biddle A (2022). Organ-on-a-Chip Technologies Network special issue editorial. Springer Nature In vitro models vol. 1, (6) 397-398.
Dembitz V, Lawson H, Philippe C, Burt RJ, James S, Magee ASM, Woodley K, Durko J, Campos J, Austin MJ, Rio-Machin A, Izquierdo PC, Bewicke-Copley F, Blanco GR, Patel B, Hazlehurst L, Peck B, Finch A, Cutillas P, Fitzgibbon J, Yuneva M, Rouault-Pierre K, Copland J, Kranc K and Gallipoli P (2022). Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia. American Society of Hematology Blood vol. 140, (Supplement 1) 3058-3060.
Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C, Uyulur F, Morton JP, Kocher HM and Grose RP (2022). Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1. Springer Nature Oncogene vol. 42, (7) 491-500.
Morera C, Kim J, Paredes-Redondo A, Nobles M, Rybin D, Moccia R, Kowala A, Meng J, Garren S, Liu P, Morgan JE, Muntoni F, Christoforou N, Owens J, Tinker A and Lin Y-Y (2022). CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model. Neuromuscular Disorders
Aslam A, Baksh A, Pape S, Consortium G-D, Strydom A, Gulliford M and Chan L (2022). Diabetes and obesity in down syndrome across the lifespan: a retrospective cohort study using UK electronic health records. Bioscientifica Endocrine Abstracts
Gautrot JE, Chang L, Alexis C, Gutfreund P and Zarbakhsh A (2022). The Architecture of Oligonucleotide-Polycationic Brush Complexes – A Neutron Reflectometry Study. Wiley Advanced Materials Interfaces
Ombrato L (2022). In vivo labelling system to study cell neighbourhoods. Springer Nature Nature Reviews Cancer vol. 22, (12) 661-661.
Caetano AJ, Caetano A, Sharpe P, Volponi AA, Yianni V, Bush M, McKay LK, Wallet S, Shazib MA, Kimple A, Byrd KM, Easter Q, Weaver T, Sequeira I, Kumar R, Pereira D, Macken J, Fortune F, Efremova M, Teichmann S, Kretzschmar K, Todres E, Boffelli D, Hagood JS, Klein O, Boucher R, Lwin S, Pranzatelli T, Beachy P and Lu WJ (2022). A Roadmap for the Human Oral and Craniofacial Cell Atlas. SAGE Publications Journal of Dental Research vol. 101, (11) 1274-1288.
Hayward M-K, Allen MD, Gomm JJ, Goulding I, Thompson CL, Knight MM, Marshall JF and Jones JL (2022). Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion. Springer Nature npj Breast Cancer vol. 8, (1)
Heywood HK, Gardner L, Knight MM and Lee DA (2022). Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems. Springer Nature In vitro models 1-8.
Cervantes-Salguero K, Freeley M, Gwyther REA, Jones DD, Chávez JL and Palma M (2022). Single molecule DNA origami nanoarrays with controlled protein orientation. AIP Publishing Biophysics Reviews vol. 3, (3)
Sun C, Dong Y, Wei J, Cai M, Liang D, Fu Y, Zhou Y, Sui Y, Wu F, Mikhaylov R, Wang H, Fan F, Xie Z, Stringer M, Yang Z, Wu Z, Tian L and Yang X (2022). Acoustically accelerated neural differentiation of human embryonic stem cells. Elsevier Acta Biomaterialia vol. 151, 333-345.
Jones CFE, Di Cio S, Connelly JT and Gautrot JE (2022). Design of an Integrated Microvascularized Human Skin-on-a-Chip Tissue Equivalent Model. Frontiers Media Frontiers in Bioengineering and Biotechnology vol. 10,
Whiteford J, Arokiasamy S, Thompson C, Alazawi W and Dufton N (2022). FRI198 Investigating the function of Endothelial-To-Mesenchymal transition during liver fibrogenesis using a Liver-On-A-Chip platform. Elsevier Journal of Hepatology vol. 77,
Scemama A, Lunetto S and Biddle A (2022). Highlight: microfluidic devices for cancer metastasis studies. Springer Nature In vitro models vol. 1, (6) 399-403.
Sarmin AM, Moussaid NE, Suntornnond R, Tyler EJ, Kim Y-H, Di Cio S, Megone WV, Pearce O, Gautrot JE, Dawson J and Connelly JT (2022). Multi-Scale Analysis of the Composition, Structure, and Function of Decellularized Extracellular Matrix for Human Skin and Wound Healing Models. MDPI Biomolecules vol. 12, (6)
Rivellese F, Surace AEA, Goldmann K, Sciacca E, Çubuk C, Giorli G, John CR, Nerviani A, Fossati-Jimack L, Thorborn G, Ahmed M, Prediletto E, Church SE, Hudson BM, Warren SE, McKeigue PM, Humby F, Bombardieri M, Barnes MR, Lewis MJ and Pitzalis C (2022). Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial. Springer Nature Nature Medicine vol. 28, (6) 1256-1268.
Wallis R, Milligan D, Hughes B, Mizen H, López-Domínguez JA, Eduputa U, Tyler EJ, Serrano M and Bishop CL (2022). Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence. Impact Journals Aging vol. 14, (10) 4220-4246.
Yu Z, Zhang J, Zhang Q, Wei S, Shi R, Zhao R, An L, Grose R, Feng D and Wang H (2022). Single‐cell sequencing reveals the heterogeneity and intratumoral crosstalk in human endometrial cancer. Wiley Cell Proliferation vol. 55, (6)
Ghorbani S, Shahrokhtash A, Gautrot JE and Sutherland DS (2022). Protein Ligand Nanopattern Size Selects for Cellular Adhesion via Hemidesmosomes over Focal Adhesions. Wiley Small Methods vol. 6, (6)
Candarlioglu PL, Dal Negro G, Hughes D, Balkwill F, Harris K, Screen H, Morgan H, David R, Beken S, Guenat O, Rowan W and Amour A (2022). Organ-on-a-chip: current gaps and future directions. Portland Press Biochemical Society Transactions vol. 50, (2) 665-673.
Swiatlowska P, Sit BHM, Zhen F, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X, Xiao Q, Shanahan C, Jones G, Yu C-H and Iskratsch T (2022). Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching. American Association for the Advancement of Science Science Advances
Kong D, Peng L, Bosch-Fortea M, Chrysanthou A, Alexis CVJM, Matellan C, Zarbakhsh A, Mastroianni G, del Rio Hernandez A and Gautrot JE (2022). Impact of the multiscale viscoelasticity of quasi-2D self-assembled protein networks on stem cell expansion at liquid interfaces. Elsevier Biomaterials vol. 284,
Yao Y, Zhou S, Alastruey J, Hao L, Greenwald SE, Zhang Y and Xu L (2022). Estimation of central pulse wave velocity from radial pulse wave analysis. Elsevier Computer Methods and Programs in Biomedicine vol. 219,
Xu L, Zhou S, Wang L, Yao Y, Hao L, Qi L, Han H, Mukkamala R and Greenwald SE (2022). Improving the accuracy and robustness of carotid-femoral pulse wave velocity measurement using a simplified tube-load model. Springer Nature Scientific Reports vol. 12, (1)
Liu W, Du S, Zhou S, Mei T, Zhang Y, Sun G, Song S, Xu L, Yao Y and Greenwald SE (2022). Noninvasive estimation of aortic pressure waveform based on simplified Kalman filter and dual peripheral artery pressure waveforms. Elsevier Computer Methods and Programs in Biomedicine vol. 219,
Zucchi H, Pageon H, Asselineau D, Ghibaudo M, Sequeira I and Girardeau-Hubert S (2022). Assessing the Role of Carbonyl Adducts, Particularly Malondialdehyde Adducts, in the Development of Dermis Yellowing Occurring during Skin Photoaging. MDPI Life vol. 12, (3)
Nguyen NT, Jennings J, Milani AH, Martino CDS, Nguyen LTB, Wu S, Mokhtar MZ, Saunders JM, Gautrot JE, Armes SP and Saunders BR (2022). Highly Stretchable Conductive Covalent Coacervate Gels for Electronic Skin. American Chemical Society (ACS) Biomacromolecules vol. 23, (3) 1423-1432.
Pundel OJ, Blowes LM and Connelly JT (2022). Extracellular Adhesive Cues Physically Define Nucleolar Structure and Function. Wiley Advanced Science vol. 9, (10)
Shen Y, Kang F, Cheng Y, Zhang K and Sui Y (2022). Numerical and theoretical analysis of fast evaporating sessile droplets with coupled fields. Elsevier International Journal of Thermal Sciences vol. 172,
Cao Y, Liu W, Zhang S, Xu L, Zhu B, Cui H, Geng N, Han H and Greenwald SE (2022). Detection and Localization of Myocardial Infarction Based on Multi-Scale ResNet and Attention Mechanism. Frontiers Frontiers in Physiology vol. 13,
Zardab M, Stasinos K, Grose RP and Kocher HM (2022). The Obscure Potential of AHNAK2. MDPI Cancers vol. 14, (3)
Malacrida B, Pearce OMT and Balkwill FR (2022). Building in vitro 3D human multicellular models of high-grade serous ovarian cancer. Elsevier STAR Protocols vol. 3, (1)
Mahmood HTNA, Tomas Bort E, Walker AJ, Grose RP and Chioni AM (2022). FGF signalling facilitates cervical cancer progression. Wiley The Federation of European Biochemical Societies (FEBS) Journal
T. Lin TL, Z. Wang ZW, R. X. Lu RXL, W. Wang WW and Y. Sui YS (2022). Characterising Mechanical Properties of Flowing Microcapsules Using a Deep Convolutional Neural Network. Global Science Press Advances in Applied Mathematics and Mechanics vol. 14, (1) 79-100.
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A, Marshall JJT, Rosewell I, Tatari M, Rajeeve V, Khan F, Wang J, Kotantaki P, Tyler EJ, Singh N, Reader CS, Carter EP, Hodivala-Dilke K, Grose RP, Kocher HM, Gavara N, Pearce O, Cutillas P, Marshall JF and Cameron AJM (2022). Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion. Elsevier Cell Reports vol. 38, (4)
Whiteford J, Arokiasamy S, Thompson CL and Dufton NP (2022). Novel application of live imaging to determine the functional cell biology of endothelial-to-mesenchymal transition (EndMT) within a liver-on-a-chip platform. Springer Nature In vitro models vol. 1, (6) 413-421.
2021
Sheikh MH, Errede M, d'Amati A, Khan NQ, Fanti S, Loiola RA, McArthur S, Purvis GSD, O'Riordan CE, Ferorelli D, Dell'Erba A, Kieswich J, Reutelingsperger C, Maiorano E, Yaqoob M, Thiemermann C, Baragetti A, Catapano AL, Norata GD, Marelli‐Berg F, Virgintino D and Solito E (2021). Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues. Wiley The FASEB Journal vol. 36, (1)
Hoyles L, Pontifex M, Rodriguez-Ramiro I, Anis-Alavi MA, Jelane KS, Snelling T, Solito E, Fonseca S, Carvalho AL, Carding SR, Muller M, Glen RC, Vauzour D and Mcarthur S (2021). Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide. BioMed Central Microbiome
Peng L and Gautrot JE (2021). Long term expansion profile of mesenchymal stromal cells at protein nanosheet-stabilised bioemulsions for next generation cell culture microcarriers. Elsevier Materials Today Bio vol. 12, 100159-100159.
Chioni A-M and Grose RP (2021). Biological Significance and Targeting of the FGFR Axis in Cancer. MDPI Cancers vol. 13, (22)
Raynold AAM, Li D, Chang L and Gautrot JE (2021). Competitive binding and molecular crowding regulate the cytoplasmic interactome of non-viral polymeric gene delivery vectors. Springer Nature Nature Communications vol. 12, (1)
Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Tzelepis K, Philippe C, Rattigan K, Asby R, Dembitz V, Magee ASM, Helgason G, Rouault-Pierre K, Vassiliou GS, Huntly BJP and Gallipoli P (2021). Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia. American Society of Hematology Blood vol. 138, (Supplement 1)
Nguyen KDQ, Crespo-Ribadeneyra M, Picot O, Colak B and Gautrot JE (2021). Ultrafast Photo-Crosslinking of Thiol–Norbornene Opaque Silicone Elastomer Nanocomposites in Air. American Chemical Society ACS Applied Polymer Materials
Joseph MD, Bort ET, Grose RP, McCormick PJ and Simoncelli S (2021). Quantitative Super-Resolution Imaging for the Analysis of GPCR Oligomerization. MDPI Biomolecules vol. 11, (10)
Smith CJ, Williams JL, Caley MP, O’Toole EA, Prasad R and Metherell LA (2021). 099 Ichthyosis associated with sphingosine 1-phosphate lyase deficiency is due to aberrant calcium and sphingolipid regulation. Journal of Investigative Dermatology vol. 141, (10) s165-s165.
Paredes-Redondo A, Harley P, Maniati E, Ryan D, Louzada S, Meng J, Kowala A, Fu B, Yang F, Liu P, Marino S, Pourquié O, Muntoni F, Wang J, Lieberam I and Lin YY (2021). Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections. Science Advances vol. 7, (37)
Costa E, Okesola BO, Thrasivoulou C, Becker DL, Deprest JA, David AL and Chowdhury TT (2021). Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma. Springer Nature Scientific Reports vol. 11, (1)
Jomrich G, Kollmann D, Ramazanova D, Ristl R, Grose RP, Ilhan-Mutlu A, Preusser M, Fassnacht C, Tsai Y-C, Guenova E and Schoppmann SF (2021). Expression of programmed cell death protein 1 (PD-1) and programmed cell death 1 ligand (PD-L1) in adenocarcinomas of the gastroesophageal junction change significantly after neoadjuvant treatment. Elsevier European Journal of Surgical Oncology vol. 48, (2) 383-390.
Xu X, Bowen BJ, Gwyther REA, Freeley M, Grigorenko B, Nemukhin AV, Eklöf‐Österberg J, Moth‐Poulsen K, Jones DD and Palma M (2021). Tuning Electrostatic Gating of Semiconducting Carbon Nanotubes by Controlling Protein Orientation in Biosensing Devices. Wiley Angewandte Chemie International Edition vol. 60, (37) 20184-20189.
Pereira D and Sequeira I (2021). A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus. Frontiers Frontiers in Cell and Developmental Biology vol. 9,
Carter EP, Roozitalab R, Gibson SV and Grose RP (2021). Tumour microenvironment 3D-modelling: simplicity to complexity and back again. Elsevier Trends in Cancer vol. 7, (11) 1033-1046.
Lu RX, Wang Z, Salsac A-V, Barthès-Biesel D, Wang W and Sui Y (2021). Path selection of a train of spherical capsules in a branched microchannel. Cambridge University Press (CUP) Journal of Fluid Mechanics vol. 923,
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Kao AP, Connelly JT and Barber AH (2016). 3D nanomechanical evaluations of dermal structures in skin. Journal of the mechanical behavior of biomedical materials vol. 57, 14-23.
Tian F-B, Wang W, Wu J and Sui Y (2016). Swimming performance and vorticity structures of a mother-calf pair of fish. COMPUTERS & FLUIDS vol. 124, 1-11.
Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM and Connelly JT (2016). Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility. J Invest Dermatol vol. 136, (1) 74-83.
2015
PALMA M, Hardy JG, Tadayyon G, Farsan M and Wind SJ (2015). Advances in Functional Assemblies for Regenerative
Medicine. Wiley Online Advanced healthcare materials vol. 4, (16) 2500-2519.
Almeida FV, Walko G, McMillan JR, McGrath JA, Wiche G, Barber AH and Connelly JT (2015). The cytolinker plectin regulates nuclear mechanotransduction in keratinocytes. The Company of Biologists Journal of Cell Science vol. 128, (24) 4475-4486.
Hossain MA, Chowdhury T and Bagul A (2015). Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. J Tissue Eng Regen Med vol. 9, (11) 1217-1224.
Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DHM, Reutelingsperger CPM, Yaqoob M and Solito E (2015). Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking. Elsevier Brain Behavior and Immunity vol. 51, 212-222.
Peake NJ, Bader DL, Vessillier S, Ramachandran M, Salter DM, Hobbs AJ and Chowdhury TT (2015). C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes. Elsevier Biochemical and Biophysical Research Communications vol. 465, (4) 784-789.
Screen HRC, Berk DE, Kadler KE, Ramirez F and Young MF (2015). Tendon Functional Extracellular Matrix. Wiley Journal of Orthopaedic Research® vol. 33, (6) 793-799.
Peake N, Pavlov A, D'Souza A, Alfasahin I, Pingaan-Murphy B, Sukhurukov G, Hobbs A and Chowdhury T (2015). Polyelectrolyte microencapsules loaded with C-type natriuretic peptide protect cartilage from IL-1B induced damage. Elsevier Osteoarthritis and Cartilage vol. 23, a141-a142.
Milagre CS, Gopinathan G, Everitt G, Thompson RG, Kulbe H, Zhong H, Hollingsworth RE, Grose R, Bowtell DDL, Hochhauser D and Balkwill FR (2015). Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer. American Association for Cancer Research (AACR) Cancer Research vol. 75, (7) 1255-1264.
Brewin MP, Birch MJ, Mehta DJ, Reeves JW, Shaw S, Kruse C, Whiteman JR, Hu S, Kenz ZR, Banks HT and Greenwald SE (2015). Characterisation of Elastic and Acoustic Properties of an Agar-Based Tissue Mimicking Material. Springer Nature Annals of Biomedical Engineering vol. 43, (10) 2587-2596.
Peake NJ, Pavlov AM, D'Souza A, Pingguan-Murphy B, Sukhorukov GB, Hobbs AJ and CHOWDHURY TT (2015). Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants. American Chemical Society Biomacromolecules
Fearon AE, Chioni A-M and Grose RP (2015). The FGFR Receptor Family. Receptor Tyrosine Kinases: Family and Subfamilies Springer Nature
2014
Thorpe CT, Chaudhry S, Lei II, Varone A, Riley GP, Birch HL, Clegg PD and Screen HRC (2014). Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation. Wiley Scandinavian Journal of Medicine and Science in Sports vol. 25, (4) e381-e391.
Carter EP, Fearon AE and Grose RP (2014). Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction. Elsevier Trends in Cell Biology vol. 25, (4) 221-233.
Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and Chowdhury TT (2014). Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function. Osteoarthritis Cartilage vol. 22, (11) 1800-1807.
Greco KV, Nalesso G, Kaneva MK, Sherwood J, Iqbal AJ, Moradi-Bidhendi N, Dell'Accio F and Perretti M (2014). Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin. Biochem Pharmacol vol. 91, (3) 348-358.
Chowdhury B, David AL, Thrasivoulou C, Becker DL, Bader DL and Chowdhury TT (2014). Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane. Elsevier Placenta vol. 35, (12) 1057-1064.
Kaneva MK, Kerrigan MJP, Grieco P, Curley GP, Locke IC and Getting SJ (2014). Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury. Elsevier Biochemical Pharmacology vol. 92, (2) 336-347.
Coleman SJ, Bruce C, Chioni A-M, Kocher HM and Grose RP (2014). The ins and outs of fibroblast growth factor receptor signalling. Clin Sci (Lond) vol. 127, (4) 217-231.
Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and CHOWDHURY TT (2014). Role of C-type natriuretic peptide signaling in maintaining cartilage and bone function. Elsevier/Science Direct Osteoarthritis and Cartilage vol. online edition,
Coleman SJ, Watt J, Arumugam P, Solaini L, Carapuca E, Ghallab M, Grose RP and Kocher HM (2014). Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation. World J Gastroenterol vol. 20, (26) 8471-8481.
Hossain MA, CHOWDHURY TT and Bagul A (2014). Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. Wiley Journal of Tissue Engineering and Regenerative Medicine
Costa P, Gautrot JE and Connelly JT (2014). Directing cell migration using micropatterned and dynamically adhesive polymer brushes. Acta Biomater vol. 10, (6) 2415-2422.
Chowdhury B, David A, Bader D, Thrasivoulou C, Becker D and Chowdhury T (2014). PFM.37 Cyclic tensile strain increases PGE2 release leading to weakening of the human term amniotic membrane. BMJ Archives of Disease in Childhood Fetal & Neonatal vol. 99, (Suppl 1)
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljević N, Chaplin T, Xue L, Xu M, Foster JM, Karnam SS, James SY, Chioni A-M, Gould D, Lorincz AT, Oliver RTD, Chelala C, Thomas GM, Shipley JM, Mather SJ, Berney DM, Young BD and Lu Y-J (2014). Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol vol. 232, (5) 566-577.
Coleman SJ, Chioni A-M, Ghallab M, Anderson RK, Lemoine NR, Kocher HM and Grose RP (2014). Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion. EMBO Mol Med vol. 6, (4) 467-481.
Parker E, Vessillier S, Abas WW, Bader DL, Pinguaan-Murphy B and Chowdhury TT (2014). α5β1 integrin mediates compression-induced inhibition of catabolic effects induced by fibronectin fragments in an oxygen-dependent manner. Elsevier Osteoarthritis and Cartilage vol. 22,
Shah FA, Brauer DS, Wilson RM, Hill RG and Hing KA (2014). Influence of cell culture medium composition on in vitro dissolution behavior of a fluoride-containing bioactive glass. Journal of Biomedical Materials Research - Part A vol. 102, (3) 647-654.
Fearon AE and Grose RP (2014). Grb-ing receptor activation by the tail. Nat Struct Mol Biol vol. 21, (2) 113-114.
Banks HT, Hu S, Kenz ZR, Kruse C, Shaw S, Whiteman J, Brewin MP, Greenwald SE and Birch MJ (2014). MODEL VALIDATION FOR A NONINVASIVE ARTERIAL STENOSIS DETECTION PROBLEM. MATHEMATICAL BIOSCIENCES AND ENGINEERING vol. 11, (3) 427-448.
2013
Fearon AE, Gould CR and Grose RP (2013). FGFR signalling in women's cancers. Int J Biochem Cell Biol vol. 45, (12) 2832-2842.
Shafat M, Rajakumar K, Syme H, Buchholz N and Knight MM (2013). Stent encrustation in feline and human artificial urine: does the low molecular weight composition account for the difference? Urolithiasis vol. 41, (6) 481-486.
Cai H, Depoil D, Palma M, Sheetz MP, Dustin ML and Wind SJ (2013). Bifunctional nanoarrays for probing the immune response at the single-molecule level. J Vac Sci Technol B Nanotechnol Microelectron vol. 31, (6)
Parker E, Vessillier S, Pinguaan-Murphy B, Wan Abas WAB, Bader DL and Chowdhury TT (2013). Low oxygen tension increased FN-f induced catabolic activities - response prevented with biomechanical signals. BioMed central Arthritis Research and Therapy vol. 15, (5) R163-R163.
Akanji O, Salter DM and Chowdhury TT (2013). Optimisation of quantitative real-time PCR studies in cartilage mechanobiology. PCR Technology. Current innovations , Editors: Nolan T and Bustin SA. CRC PressI Llc
Guasti L, Candy Sze WC, McKay T, Grose R and King PJ (2013). FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Mol Cell Endocrinol vol. 371, (1-2) 182-188.
Parker E, Pinguuan-Murphy B, Bader DL and Chowdhury TT (2013). FN-f induced catabolic activities are dependent on oxygen tension in chondrocyte/agarose constructs subjected to biomechanical signals. Elsevier Osteoarthritis and Cartilage vol. 21,
Campion CR, Ball SL, Clarke DL and Hing KA (2013). Microstructure and chemistry affects apatite nucleation on calcium phosphate bone graft substitutes. Journal of Materials Science: Materials in Medicine vol. 24, (3) 597-610.
Hossain MA, Frampton AE, Chowdhury TT and Morsey M (2013). Biological vascular grafts for hemodialysis access. Informa healthcare Expert Rev Med Devices vol. 2, (10) 171-175.
Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, McEvoy A, Dinsdale D, Condorelli F, Brandner S, Campanella M, Grose R, Jones C and Salomoni P (2013). The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene vol. 32, (6) 699-712.
Mafina M-K, Hing KA and Sullivan AC (2013). Development of novel fluorescent probes for the analysis of protein interactions under physiological conditions with medical devices. Langmuir vol. 29, (5) 1420-1426.
Legerlotz K, Jones GC, Screen HRC and Riley GP (2013). Cyclic loading of tendon fascicles using a novel fatigue loading system increases interleukin-6 expression by tenocytes. Scandinavian Journal of Medicine and Science in Sports vol. 23, (1) 31-37.
Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ and Chowdhury TT (2013). Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D / bioreactor model. Bio Med Central Arthritis Research and Therapy vol. 15, (4)
Robbez-Masson LJ, Bödör C, Jones JL, Hurst HC, Fitzgibbon J, Hart IR and Grose RP (2013). Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. PLoS One vol. 8, (11)
Greenwald SE, Banks HT, Birch MJ, Brewin MP, Hu S, Kenz ZR, Kruse C, Mehta D, Reeves J, Shaw S and Whiteman JR (2013). P2.20: Acoustic Localisation of Coronary Artery Stenosis: Wave Propagation in Soft Tissue Mimicking Gels. Springer Nature Artery Research vol. 7, (3-4) 124-124.
Akanji O, Salter D and Chowdhury T (2013). Optimization of Quantitative Real-Time PCR for Studies in Cartilage Mechanobiology. PCR Technology: Current Innovations, Third Edition
2012
Meyer M, Müller A-K, Yang J, Moik D, Ponzio G, Ornitz DM, Grose R and Werner S (2012). FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin. J Cell Sci vol. 125, (Pt 23) 5690-5701.
Brewin M, Greenwald , Shaw S, Kruse C, Whiteman and Birch M (2012). CHARACTERISATION OF AGAROSE GEL AS A TISSUE MIMIC MATERIAL (TMM) FOR USE IN AN ANTHROPOMORPHIC TEST OBJECT INVESTIGATING THE ACOUSTIC LOCALISATION OF CORONARY STENOSIS. Elsevier Journal of Biomechanics vol. 45,
Chioni A-M and Grose R (2012). FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior. J Cell Biol vol. 197, (6) 801-817.
Tsang SM, Brown L, Lin K, Liu L, Piper K, O'Toole EA, Grose R, Hart IR, Garrod DR, Fortune F and Wan H (2012). Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris. J Pathol vol. 227, (1) 81-93.
Driskell RR, Juneja VR, Connelly JT, Kretzschmar K, Tan DW-M and Watt FM (2012). Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and -negative cells in vitro and in vivo. J Invest Dermatol vol. 132, (4) 1084-1093.
CHOWDHURY TT, Tilwani RK and Bader DL (2012). Biomechanical conditioning enhanced matrix synthesis in nucleus pulposus cells cultured in agarase constructs with TGFβ., Editors: Goldsmith EC and Lin SK. Journal Functional Biomaterials vol. 3, 23-26.
Trappmann B, Gautrot JE, Connelly JT, Strange DGT, Li Y, Oyen ML, Cohen Stuart MA, Boehm H, Li B, Vogel V, Spatz JP, Watt FM and Huck WTS (2012). Extracellular-matrix tethering regulates stem-cell fate. Nature Materials
Jarosz M, Robbez-Masson L, Chioni A-M, Cross B, Rosewell I and Grose R (2012). Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis. PLoS One vol. 7, (6)
2011
Guth K, Campion C, Buckland T and Hing KA (2011). Effects of serum protein on ionic exchange between culture medium and microporous hydroxyapatite and silicate-substituted hydroxyapatite. Journal of Materials Science: Materials in Medicine vol. 22, (10) 2155-2164.
Ramachandran M, Achan P, Salter DM, Bader DL and Chowdhury TT (2011). Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs. Arthritis Research and Therapy vol. 13, (5)
Palma M, Abramson JJ, Gorodetsky AA, Penzo E, Gonzalez RL, Sheetz MP, Nuckolls C, Hone J and Wind SJ (2011). Selective biomolecular nanoarrays for parallel single-molecule investigations. J Am Chem Soc vol. 133, (20) 7656-7659.
Schvartzman M, Palma M, Sable J, Abramson J, Hu X, Sheetz MP and Wind SJ (2011). Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level. Nano Lett vol. 11, (3) 1306-1312.
Bader DL, Salter DM and Chowdhury TT (2011). Biomechanical influence of cartilage homeostasis in health and disease. Arthritis vol. 2011,
Palma M, Abramson JJ, Gorodetsky AA, Nuckolls C, Sheetz MP, Wind SJ and Hone J (2011). Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization. Methods Mol Biol vol. 749, 169-185.
Penzo E, Wang R, Palma M and Wind SJ (2011). Selective placement of DNA origami on substrates patterned by nanoimprint lithography. JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B vol. 29, (6)
Lee DA, Brand J, Salter D, Akanji O-O and Chowdhury TT (2011). Quantification of mRNA using real-time PCR and Western blot analysis of MAPK events in chondrocyte/agarose constructs. Methods Mol Biol vol. 695, 77-97.
2010
Connelly JT, Gautrot JE, Trappmann B, Tan DWM, Donati G, Huck WTS and Watt FM (2010). Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nature Cell Biology vol. 12, (7) 711-718.
Connelly JT, Vanderploeg EJ, Mouw JK, Wilson CG and Levenston ME (2010). Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs. Tissue Eng Part A vol. 16, (6) 1913-1923.
Chowdhury TT, Schulz RM, Rai SS, Thuemmler CB, Wuestneck N, Bader A and Homandberg GA (2010). Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs. Arthritis Research and Therapy vol. 12, (3)
Guth K, Campion C, Buckland T and Hing KA (2010). Surface physiochemistry affects protein adsorption to stoichiometric and silicate-substituted microporous hydroxyapatites. Advanced Engineering Materials vol. 12, (4)
Yang J, Meyer M, Müller A-K, Böhm F, Grose R, Dauwalder T, Verrey F, Kopf M, Partanen J, Bloch W, Ornitz DM and Werner S (2010). Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol vol. 188, (6) 935-952.
Screen HRC, Byers S, Lynn AD, Nguyen V, Patel D and Bryant SJ (2010). Characterization of a novel fiber composite material for mechanotransduction research of fibrous connective tissues. Advanced Functional Materials vol. 20, (5) 738-747.
Turner N and Grose R (2010). Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer vol. 10, (2) 116-129.
Chioni A-M, Shao D, Grose R and Djamgoz MBA (2010). Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration. Int J Biochem Cell Biol vol. 42, (2) 346-358.
Guth K, Campion C, Buckland T and Hing KA (2010). Effect of silicate-substitution on attachment and early development of human osteoblast-like cells seeded on microporous hydroxyapatite discs. Advanced Engineering Materials vol. 12, (1-2)
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V and Hodivala-Dilke KM (2010). Regulation of lymphatic-blood vessel separation by endothelial Rac1 (vol 136, pg 4043, 2009). DEVELOPMENT vol. 137, (2) 359-359.
McGlashan SR, Knight MM, Chowdhury TT, Joshi P, Jensen CG, Kennedy S and Poole CA (2010). Mechanical loading modulates chondrocyte primary cilia incidence and length. Cell Biology International vol. 34, (5) 441-446.
Akanji OO, Sakthithasan P, Salter DM and Chowdhury TT (2010). Dynamic compression alters NFκB activation and IκB-α expression in IL-1β-stimulated chondrocyte/agarose constructs. Inflammation Research vol. 59, (1) 41-52.
Tsang SM, Liu L, Teh M-T, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F and Wan H (2010). Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. PlosOne PloS ONE vol. 5, (12)
2009
Akanji OO, Salter DM and Chowdhury TT (2009). 458 DYNAMIC COMPRESSION ALTERS NF?B ACTIVATION AND I?B-α EXPRESSION IN IL-1β STIMULATED CHONDROCYTE/AGAROSE CONSTRUCTS. Elsevier Osteoarthritis and Cartilage vol. 17, s245-s246.
Chioni A-M and Grose R (2009). Negative regulation of fibroblast growth factor 10 (FGF-10) by polyoma enhancer activator 3 (PEA3). Eur J Cell Biol vol. 88, (7) 371-384.
Raveenthiran SP and Chowdhury TT (2009). Dynamic compression inhibits fibronectin fragment induced iNOS and COX-2 expression in chondrocyte/agarose constructs. Biomechanics and Modeling in Mechanobiology vol. 8, (4) 273-283.
2008
Chioni A-M and Grose R (2008). Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis. Fibrogenesis Tissue Repair vol. 1, (1)
Connelly JT, García AJ and Levenston ME (2008). Interactions between integrin ligand density and cytoskeletal integrity regulate BMSC chondrogenesis. J Cell Physiol vol. 217, (1) 145-154.
Raveenthiran SP and Chowdhury TT (2008). 451 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN-FRAGMENT INDUCED INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS. Elsevier Osteoarthritis and Cartilage vol. 16, s195-s196.
Chowdhury TT, Salter DM, Bader DL and Lee DA (2008). Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression. INFLAMM RES vol. 57, (7) 306-313.
Rashid N, Harding I, Buckland T and HING KA (2008). Nano-scale manipulation of silicate-substituted apatite chemistry impacts surface charge, hydrophilicity, protein adsorption and cell attachment., Editors: Meenan BJ and Boyd AR. International Journal of Nano and Biomaterials vol. 1, (3) 299-319.
CHOWDHURY TT, Akanjii OO, Salter DM and Lee DA (2008). Dynamic compression influences IL-1β induced NO and PGE2 release, via alterations in iNOS and COX-2 activity. 5th International Symposium on Mechanobiology of Cartilage and Chondrocyte , Editors: Stoltz JF.
Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM and Lee DA (2008). Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs. Arthritis Res Ther vol. 10, (2)
Chowdhury TT, Akanji OO, Salter DM, Bader DL and Lee DA (2008). Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression. BIORHEOLOGY vol. 45, (3-4) 257-274.
2007
Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL and Lee DA (2007). 52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION. Elsevier Osteoarthritis and Cartilage vol. 15, c42-c43.
Campbell JJ, Blain EJ, Chowdhury TT and Knight MM (2007). Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes. Biochemical and Biophysical Research Communications vol. 361, (2) 329-334.
Grose R, Fantl V, Werner S, Chioni A-M, Jarosz M, Rudling R, Cross B, Hart IR and Dickson C (2007). The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development. EMBO J vol. 26, (5) 1268-1278.
Connelly JT, García AJ and Levenston ME (2007). Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels. Biomaterials vol. 28, (6) 1071-1083.
2006
Chowdhury TT and Knight MM (2006). Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. Journal of Cellular Physiology vol. 209, (3) 845-853.
Chowdhury TT, Appleby RN, Salter DM, Bader DA and Lee DA (2006). Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes. Biomech Model Mechanobiol vol. 5, (2-3) 192-201.
Chowdhury TT, Bader DL and Lee DA (2006). Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes. Biochem Biophys Res Commun vol. 339, (1) 241-247.
CHOWDHURY TT, Bader DL and Lee DA (2006). Dynamic compression counteracts IL-1β induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Mechanobiology: Cartilage and Chondrocyte , Editors: Stoltz JF. IOS Press
Chowdhury TT, Bader DL and Lee DA (2006). Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Biorheology vol. 43, (3,4) 413-429.
Chowdhury TT, Raveenthiran SP, Bader DL and Lee DA (2006). P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE. Elsevier Osteoarthritis and Cartilage vol. 14,
2005
Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Proceedings of the 2005 Summer Bioengineering Conference vol. 2005, 251-252.
Chowdhury TT, Appleby RN, Salter DA, Bader DL and Lee DA (2005). Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs. Proceedings of the 2005 Summer Bioengineering Conference vol. 2005, 545-546.
Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs. European Cells and Materials vol. 10, (SUPPL.2)
Catuogno C, Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs. European Cells and Materials vol. 10, (SUPPL.2)
(2005). British Society for Matrix Biology Autumn Meeting Joint with the UK Tissue & Cell Engineering Society, University of Bristol, UK. Wiley International Journal of Experimental Pathology vol. 86, (3) a1-a56.
Grose R and Dickson C (2005). Fibroblast growth factor signaling in tumorigenesis. Cytokine Growth Factor Rev vol. 16, (2) 179-186.
Reynolds LE, Conti FJ, Lucas M, Grose R, Robinson S, Stone M, Saunders G, Dickson C, Hynes RO, Lacy-Hulbert A and Hodivala-Dilke K (2005). Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. Nat Med vol. 11, (2) 167-174.
2004
Grose R and Werner S (2004). Wound-healing studies in transgenic and knockout mice. Mol Biotechnol vol. 28, (2) 147-166.
Chowdhury TT, Salter DM, Bader DL and Lee DA (2004). Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes. Biochem Biophys Res Commun vol. 318, (4) 873-881.
Bryant SJ, Chowdhury TT, Lee DA, Bader DL and Anseth KS (2004). Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng vol. 32, (3) 407-417.
Zhang HB, Dessimoz J, Beyer TA, Krampert M, Williams LT, Werner S and Grose R (2004). Fibroblast growth factor receptor 1-lllb is dispensable for skin morphogenesis and wound healing. EUR J CELL BIOL vol. 83, (1) 3-11.
Grose R (2004). Common ground in the transcriptional profiles of wounds and tumors. Genome Biol vol. 5, (6)
2003
Young P, Boussadia O, Halfter H, Grose R, Berger P, Leone DP, Robenek H, Charnay P, Kemler R and Suter U (2003). E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J vol. 22, (21) 5723-5733.
Petiot A, Conti FJA, Grose R, Revest J-M, Hodivala-Dilke KM and Dickson C (2003). A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development vol. 130, (22) 5493-5501.
Grose R (2003). Epithelial migration: open your eyes to c-Jun. Curr Biol vol. 13, (17) R678-R680.
Chowdhury TT, Bader DL, Shelton JC and Lee DA (2003). Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression. Arch Biochem Biophys vol. 417, (1) 105-111.
Chowdhury TT, Bader DL and Lee DA (2003). Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs. Osteoarthritis Cartilage vol. 11, (9) 688-696.
Beyer TA, Werner S, Dickson C and Grose R (2003). Fibroblast growth factor 22 and its potential role during skin development and repair. EXP CELL RES vol. 287, (2) 228-236.
Werner S and Grose R (2003). Regulation of wound healing by growth factors and cytokines. Physiol Rev vol. 83, (3) 835-870.
Martin P, D'Souza D, Martin J, Grose R, Cooper L, Maki R and McKercher SR (2003). Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells. Curr Biol vol. 13, (13) 1122-1128.
Chowdhury TT, Shelton JC, Bader DL and LEE DA (2003). Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs. Internat. J. Artificial Organs vol. 26, (9) 858-858.
Chowdhury TT, LEE DA, Salter DM, Shelton JC and Bader DL (2003). alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression. Osteoarthritis Cartilage vol. 11, (Suppl 1) S2-S3.
Grose R and Werner S (2003). Wound Healing Studies in Transgenic and Knockout Mice. Wound Healing Springer Nature
Grose R and Werner S (2003). Wound healing studies in transgenic and knockout mice. A review. Methods Mol Med vol. 78, 191-216.
2002
Wood W, Jacinto A, Grose R, Woolner S, Gale J, Wilson C and Martin P (2002). Wound healing recapitulates morphogenesis in Drosophila embryos. NAT CELL BIOL vol. 4, (11) 907-912.
Grose R, Werner S, Kessler D, Tuckermann J, Huggel K, Durka S and Reichardt HM (2002). A role for endogenous glucocorticoids in wound repair. EMBO Rep vol. 3, (6) 575-582.
Grose R, Hutter C, Bloch W, Thorey I, Watt FM, Fässler R, Brakebusch C and Werner S (2002). A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development vol. 129, (9) 2303-2315.
Grose R and Werner S (2002). An aPPARently protective mechanism for keratinocytes in wounded skin. TRENDS MOL MED vol. 8, (4) 149-151.
Grose R, Harris BS, Cooper L, Topilko P and Martin P (2002). Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse. Dev Dyn vol. 223, (3) 371-378.
2001
Chowdhury TT, Bader DL and Lee DA (2001). Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs. Biochem Biophys Res Commun vol. 285, (5) 1168-1174.
2000
Chowdhury TT, Bader DL and Lee DA (2000). Dynamic compression inhibits the synthesis of nitric oxide by IL-1β stimulated chondrocytes cultured in agarose constructs. Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell
Bloch W, Huggel K, Sasaki T, Grose R, Bugnon P, Addicks K, Timpl R and Werner S (2000). The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing. Wiley The FASEB Journal vol. 14, (15) 2373-2376.
Brakebusch C, Grose R, Quondamatteo F, Ramirez A, Jorcano JL, Pirro A, Svensson M, Herken R, Sasaki T, Timpl R, Werner S and Fässler R (2000). Skin and hair follicle integrity is crucially dependent on β1 integrin expression on keratinocytes. Springer Nature The EMBO Journal vol. 19, (15) 3990-4003.
1999
Grose R and Martin P (1999). Parallels between wound repair and morphogenesis in the embryo. Elsevier Seminars in Cell and Developmental Biology vol. 10, (4) 395-404.