Publications
The following journal papers published by the members of the CPM, specifically relate to the development and/or use of predictive in vitro models.
- Photoelectrochemical imaging of single cardiomyocytes and monitoring of their action potentials through contact force manipulation of organoids
Jacques R, Zhou B, Marhuenda E, Gorecki J, Das A, Iskratsch T, Krause S
Biosensors and Bioelectronics, Elsevier
21-12-2022 - Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance
Croft CL, Paterno G, Vause AR, Rowe LA, Ryu DH, Goodwin MS, Moran CA, Cruz PE et al.
Npj Parkinson's Disease, Springer Nature vol. 8 (1)
19-12-2022 - Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
Khalil B, Chhangani D, Wren MC, Smith CL, Lee JH, Li X, Puttinger C, Tsai C-W et al.
Molecular Neurodegeneration, Springer Nature vol. 17 (1)
08-12-2022 - 181 Sphingosine 1-phosphate lyase insufficiency induced ichthyosis is due to sphingolipid imbalance, increased differentiation, and aberrant intercellular junctions
Smith CJ, Williams JL, Hall C, Caley MP, O’Toole EA, Prasad R, Metherell LA
Journal of Investigative Dermatology, Elsevier vol. 142 (12)
01-12-2022 - 200 Optimised 3D skin models incorporating microbiome and host immune responses
McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R
Journal of Investigative Dermatology, Elsevier vol. 142 (12)
01-12-2022 - Regulation of Cardiomyocyte Adhesion and
Mechanosignalling Through Distinct Nanoscale Behaviour of
Integrin Ligands Mimicking Healthy or Fibrotic ECM
Iskratsch T, Hawkes W, Marhuenda E, Reynolds P, O'Neill C, PANDEY P, Wilson D, FREELEY M et al.
Philosophical Transactions of The Royal Society B: Biological Sciences, The Royal Society
21-11-2022 - Organ-on-a-Chip Technologies Network special issue editorial
Biddle A
In Vitro Models, Springer Nature vol. 1 (6), 397-398.
17-11-2022 - Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia
Dembitz V, Lawson H, Philippe C, Burt RJ, James S, Magee ASM, Woodley K, Durko J et al.
Blood, American Society of Hematology vol. 140 (Supplement 1), 3058-3060.
15-11-2022 - Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1
Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C et al.
Oncogene, Springer Nature vol. 42 (7), 491-500.
10-11-2022 - Photoelectrochemical Detection of Calcium Ions Based on Hematite Nanorod Sensors
Zhou B, Jiang Y, Guo Q, Das A, Jorge Sobrido A, Hing K, Zayats A, Krause S
Acs Applied Nano Materials, American Chemical Society
10-11-2022 - CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model
Morera C, Kim J, Paredes-Redondo A, Nobles M, Rybin D, Moccia R, Kowala A, Meng J et al.
Neuromuscular Disorders
01-11-2022 - Identification of a novel specific small-molecule melanocortin-2-receptor antagonist
Chan L
Endocrine Connections, Bioscientifica vol. 11 (12)
31-10-2022 - The Architecture of Oligonucleotide-Polycationic Brush Complexes – A Neutron Reflectometry Study
Gautrot JE, Chang L, Alexis C, Gutfreund P, Zarbakhsh A
Advanced Materials Interfaces, Wiley
13-10-2022 - In vivo labelling system to study cell neighbourhoods
Ombrato L
Nature Reviews Cancer, Springer Nature vol. 22 (12), 661-661.
29-09-2022 - A Roadmap for the Human Oral and Craniofacial Cell Atlas
Caetano AJ, Caetano A, Sharpe P, Volponi AA, Yianni V, Bush M, McKay LK, Wallet S et al.
Journal of Dental Research, Sage Publications vol. 101 (11), 1274-1288.
26-09-2022 - ESDR200 - Optimised 3D skin models incorporating microbiome and host immune responses
McPolin-Hall E, Stephens A, Pardieu C, Allaker R, Philpott M, Pople J, Hannen R
, Morressier
26-09-2022 - Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion
Hayward M-K, Allen MD, Gomm JJ, Goulding I, Thompson CL, Knight MM, Marshall JF, Jones JL
Npj Breast Cancer, Springer Nature vol. 8 (1)
20-09-2022 - JAG1-NOTCH4 mechanosensing drives atherosclerosis
Souilhol C, Ayllon BT, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D et al.
Science Advances, American Association For The Advancement of Science vol. 8 (35)
02-09-2022 - Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems
Heywood HK, Gardner L, Knight MM, Lee DA
In Vitro Models, Springer Nature, 1-8.
31-08-2022 - Single molecule DNA origami nanoarrays with controlled protein orientation
Cervantes-Salguero K, Freeley M, Gwyther REA, Jones DD, Chávez JL, Palma M
Biophysics Reviews, Aip Publishing vol. 3 (3)
18-08-2022 - Bioengineering Human Cartilage-Bone Tissues for Modeling of Osteoarthritis.
Wu JY, Vunjak-Novakovic G
Stem Cells Dev vol. 31 (15-16), 399-405.
01-08-2022 - Acoustically accelerated neural differentiation of human embryonic stem cells
Sun C, Dong Y, Wei J, Cai M, Liang D, Fu Y, Zhou Y, Sui Y et al.
Acta Biomaterialia, Elsevier vol. 151, 333-345.
29-07-2022 - Design of an Integrated Microvascularized Human Skin-on-a-Chip Tissue Equivalent Model
Jones CFE, Di Cio S, Connelly JT, Gautrot JE
Frontiers in Bioengineering and Biotechnology, Frontiers Media vol. 10
19-07-2022 - FRI198 Investigating the function of Endothelial-To-Mesenchymal transition during liver fibrogenesis using a Liver-On-A-Chip platform
Whiteford J, Arokiasamy S, Thompson C, Alazawi W
Journal of Hepatology, Elsevier vol. 77
01-07-2022 - Light-Addressable Electrochemical Sensors toward Spatially Resolved Biosensing and Imaging Applications
Meng Y, Chen F, Wu C, Krause S, Wang J, Zhang DW
Acs Sensors, American Chemical Society
28-06-2022 - Highlight: microfluidic devices for cancer metastasis studies
Scemama A, Lunetto S, Biddle A
In Vitro Models, Springer Nature vol. 1 (6), 399-403.
27-06-2022 - Multi-Scale Analysis of the Composition, Structure, and Function of Decellularized Extracellular Matrix for Human Skin and Wound Healing Models
Sarmin AM, Moussaid NE, Suntornnond R, Tyler EJ, Kim Y-H, Di Cio S, Megone WV, Pearce O et al.
Biomolecules, Mdpi vol. 12 (6)
16-06-2022 - A host–gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood–brain barrier integrity in vivo
Stachulski AV, Knausenberger TB-A, Shah SN, Hoyles L, McArthur S
Tissue Barriers, Informa Uk Limited vol. 11 (1)
20-05-2022 - Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
Rivellese F, Surace AEA, Goldmann K, Sciacca E, Çubuk C, Giorli G, John CR, Nerviani A et al.
Nature Medicine, Springer Nature vol. 28 (6), 1256-1268.
19-05-2022 - Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence
Wallis R, Milligan D, Hughes B, Mizen H, López-Domínguez JA, Eduputa U, Tyler EJ, Serrano M et al.
Aging, Impact Journals, Llc vol. 14 (10), 4220-4246.
16-05-2022 - Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression
Parry CM, Chan LF, Carr DF, Hawcutt DB
Pediatric Research, Springer Nature vol. 93 (1), 97-101.
14-05-2022 - Single‐cell sequencing reveals the heterogeneity and intratumoral crosstalk in human endometrial cancer
Yu Z, Zhang J, Zhang Q, Wei S, Shi R, Zhao R, An L, Grose R et al.
Cell Proliferation, Wiley vol. 55 (6)
13-05-2022 - Protein Ligand Nanopattern Size Selects for Cellular Adhesion via Hemidesmosomes over Focal Adhesions
Ghorbani S, Shahrokhtash A, Gautrot JE, Sutherland DS
Small Methods, Wiley vol. 6 (6)
22-04-2022 - Organ-on-a-chip: current gaps and future directions
Candarlioglu PL, Dal Negro G, Hughes D, Balkwill F, Harris K, Screen H, Morgan H, David R et al.
Biochemical Society Transactions, Portland Press vol. 50 (2), 665-673.
19-04-2022 - Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching
Swiatlowska P, Sit B, Feng Z, Marhuenda E, Xanthis I, Zingaro S, Ward M, Zhou X et al.
Science Advances, American Association For The Advancement of Science (Aaas) vol. 8 (15)
15-04-2022 - Impact of the multiscale viscoelasticity of quasi-2D self-assembled protein networks on stem cell expansion at liquid interfaces
Kong D, Peng L, Bosch-Fortea M, Chrysanthou A, Alexis CVJM, Matellan C, Zarbakhsh A, Mastroianni G et al.
Biomaterials, Elsevier vol. 284
06-04-2022 - Estimation of central pulse wave velocity from radial pulse wave analysis
Yao Y, Zhou S, Alastruey J, Hao L, Greenwald SE, Zhang Y, Xu L, Xu L et al.
Computer Methods and Programs in Biomedicine, Elsevier vol. 219
27-03-2022 - Improving the accuracy and robustness of carotid-femoral pulse wave velocity measurement using a simplified tube-load model
Xu L, Zhou S, Wang L, Yao Y, Hao L, Qi L, Yao Y, Han H et al.
Scientific Reports, Springer Nature vol. 12 (1)
25-03-2022 - Noninvasive estimation of aortic pressure waveform based on simplified Kalman filter and dual peripheral artery pressure waveforms
Liu W, Du S, Zhou S, Mei T, Zhang Y, Sun G, Song S, Xu L et al.
Computer Methods and Programs in Biomedicine, Elsevier vol. 219
17-03-2022 - Assessing the Role of Carbonyl Adducts, Particularly Malondialdehyde Adducts, in the Development of Dermis Yellowing Occurring during Skin Photoaging
Zucchi H, Pageon H, Asselineau D, Ghibaudo M, Sequeira I, Girardeau-Hubert S
Life, Mdpi vol. 12 (3)
10-03-2022 - Fabrication of Human Skin Equivalents Using Decellularized Extracellular Matrix
Sarmin AM, Connelly JT
Current Protocols, Wiley vol. 2 (3)
01-03-2022 - Highly Stretchable Conductive Covalent Coacervate Gels for Electronic Skin
Nguyen NT, Jennings J, Milani AH, Martino CDS, Nguyen LTB, Wu S, Mokhtar MZ, Saunders JM et al.
Biomacromolecules, American Chemical Society (Acs) vol. 23 (3), 1423-1432.
21-02-2022 - CRISPR-mediated correction of skeletal muscle Ca2+handling in a novel DMD patient-derived pluripotent stem cell model
Morera C, Kim J, Paredes-Redondo A, Nobles M, Rybin D, Moccia R, Kowala A, Meng J et al.
18-02-2022 - Extracellular Adhesive Cues Physically Define Nucleolar Structure and Function
Pundel OJ, Blowes LM, Connelly JT
Advanced Science, Wiley vol. 9 (10)
05-02-2022 - Numerical and theoretical analysis of fast evaporating sessile droplets with coupled fields
Shen Y, Kang F, Cheng Y, Zhang K, Sui Y
International Journal of Thermal Sciences, Elsevier vol. 172
01-02-2022 - Detection and Localization of Myocardial Infarction Based on Multi-Scale ResNet and Attention Mechanism
Cao Y, Liu W, Zhang S, Xu L, Zhu B, Cui H, Geng N, Han H et al.
Frontiers in Physiology, Frontiers vol. 13
28-01-2022 - The Obscure Potential of AHNAK2
Zardab M, Stasinos K, Grose RP, Kocher HM
Cancers, Mdpi vol. 14 (3)
21-01-2022 - OP37 Bacterial suppression of intestinal fungi via activation of human gut Vδ2+ T-cells
Mathew L, Savage M, Pardieu C, O’Brien M, Sze SK, Eberl M, Stagg A, Gasparetto M et al.
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 16 (Supplement_1), i043-i044.
21-01-2022 - Building in vitro 3D human multicellular models of high-grade serous ovarian cancer
Malacrida B, Pearce OMT, Balkwill FR
Star Protocols, Elsevier vol. 3 (1)
11-01-2022 - FGF signalling facilitates cervical cancer progression
Mahmood HTNA, Tomas Bort E, Walker AJ, Grose RP, Chioni AM
The Federation of European Biochemical Societies (Febs) Journal, Wiley
03-01-2022 - Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al.
Cell Reports, Elsevier vol. 38 (4)
01-01-2022 - Novel application of live imaging to determine the functional cell biology of endothelial-to-mesenchymal transition (EndMT) within a liver-on-a-chip platform
Whiteford J, Arokiasamy S, Thompson CL, Dufton NP
In Vitro Models, Springer Nature vol. 1 (6), 413-421.
01-01-2022