Prof Amrita Ahluwalia
Dean For Research Faculty of Medicine and Dentistry
The William Harvey Research Institute
Queen Mary University of London
Queen Mary University of London
Research
Sex differences, Nitrite/Nitrate/Nitric oxide, Xanthine oxidoreductase, inflammation, cardiovascular
Interests
Sex differences in drug action related to treatment of cardiovascular disease is neglected, however, most drugs removed for use by the FDA relate to adverse effects in women. I am interested in exploring sex differences using in vitro models. Separately the enzyme xanthine oxidoreductase has been implicated in cardiovascular disease development. We have developed small molecules that target this enzyme and identified rare mutations that are linked with disease. Exploring drug action in genetic models in vitro is of interest.Publications
2024
Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Learoyd AE, Forooghi N, Ramaseshan R, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Jones DA (2024). CTCA Prior to Invasive Coronary Angiography in Patients With Previous Bypass Surgery: Patient-Related Outcomes, Imaging Resource Utilization, and Cardiac Events at 3 Years From the BYPASS-CTCA Trial. Wolters Kluwer Circulation Cardiovascular Interventions Massimo G, Dyson N, Olotu F, Khambata RS and Ahluwalia A (2024). Potential Opportunities for Pharmacogenetic-Based Therapeutic Exploitation of Xanthine Dehydrogenase in Cardiovascular Disease. MDPI Antioxidants vol. 13, (12) Rathod KS, Mathur A, Shabbir A, Khambata RS, Lau C, Beirne A-M, Chhetri I, Ono M, Belgaid DR, Massimo G, Ramasamy A, Tufaro V, Jain AK, Poulter N, Falaschetti E, Jones DA, Garcia-Garcia HM, Bourantas C, Learoyd A, Warren HR and Ahluwalia A (2024). The NITRATE-OCT study-inorganic nitrate reduces in-stent restenosis in patients with stable coronary artery disease: a double-blind, randomised controlled trial. Elsevier EClinicalMedicine vol. 77, Insel PA, Amara SG and Ahluwalia A (2024). Introduction to the Theme “Novel Therapeutics with the Potential to Advance Health Care”. Annual Reviews The Annual Review of Pharmacology and Toxicology Jones DA, Beirne A-M, Kelham M, Wynne L, Andiapen M, Rathod KS, Parakaw T, Adams J, Learoyd A, Khan K, Godec T, Wright P, Antoniou S, Wragg A, Yaqoob M, Mathur A and Ahluwalia A (2024). Inorganic nitrate benefits contrast-induced nephropathy after coronary angiography for acute coronary syndromes: the NITRATE-CIN trial. Oxford University Press (OUP) European Heart Journal vol. 45, (18) 1647-1658. Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Ramaseshan R, Learoyd AE, Forooghi N, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A, Jones DA and Investigators FTB-CT (2024). The effect of CTCA guided selective invasive graft assessment on coronary angiographic parameters and outcomes: Insights from the BYPASS-CTCA trial. Elsevier Journal of Cardiovascular Computed Tomography vol. 18, (3) 291-296. 2023
Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A, Haffner C, Ahluwalia A, Seker BF and Plesnila N (2023). Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke. Springer Nature Journal of Neuroinflammation vol. 20, (1) Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod K, Borghi C and Ahluwalia A (2023). Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]. Elsevier Redox Biology vol. 67, Jones DA, Beirne A-M, Kelham M, Rathod KS, Andiapen M, Wynne L, Godec T, Forooghi N, Ramaseshan R, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Committees and Investigators FTB-CT (2023). Computed Tomography Cardiac Angiography Before Invasive Coronary Angiography in Patients With Previous Bypass Surgery: The BYPASS-CTCA Trial. Wolters Kluwer Circulation vol. 148, (18) 1371-1380. Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N, Kapil V, Godec T, Apea V, Flint J, Orkin C, Rathod KS and Ahluwalia A (2023). A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study. Springer Nature Trials vol. 24, (1) Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod KS, Borghi C and Ahluwalia A (2023). Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health? Elsevier Redox Biology vol. 67, Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A and Raimondi C (2023). Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow. American Association for the Advancement of Science (AAAS) Science Signaling vol. 16, (786) Panettieri RA, Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P and Ahluwalia A (2023). BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure. Wiley British Journal of Pharmacology vol. 180, (12) 1537-1541. Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Panettieri RA, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P and Ahluwalia A (2023). Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology. Wiley British Journal of Pharmacology vol. 180, (9) 1191-1196. Hikin LJ, Ho J, Morley SR, Ahluwalia A and Smith PR (2023). Sodium nitrite poisoning: A series of 20 fatalities in which post-mortem blood nitrite and nitrate concentrations are reported. Elsevier Forensic Science International vol. 345, Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC, Bansal J, Pitrola K, Shaw C, D'Acquisto F, Colas RA, Marelli-Berg F, Dalli J and Ahluwalia A (2023). Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans. American Society for Clinical Investigation Journal of Clinical Investigation vol. 133, (2) 2022
Fernandes D, Khambata RS, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M, Barnes MR, Wade WG, Godec T, Orlandi M, D'Aiuto F and Ahluwalia A (2022). Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis. Elsevier Pharmacological Research vol. 188, Ingrande J, Patel HH, Kendall D, Stefanska B, Alexander S, Bakhle M, Cirino G, Docherty JR, George CH, Insel PA, Ji Y, King BF, Lilley E, Panettieri RA, Ramage AG, Sobey CG, Stanford SC, Stephens G, Teixeira M, Vergnolle N and Ahluwalia A (2022). Guidance for the use and reporting of anaesthetic agents in BJP manuscripts involving work with animals. Wiley British Journal of Pharmacology vol. 180, (3) 255-263. Hikin L, Ahluwalia A, Morley S and Smith P (2022). Sodium nitrite poisoning; A case series of 15 fatalities. Elsevier Toxicologie Analytique et Clinique vol. 34, (3) s48-s49. Curtis MJ, Alexander SPH, Cirino G, George CH, Kendall DA, Insel PA, Izzo AA, Ji Y, Panettieri RA, Patel HH, Sobey CG, Stanford SC, Stanley P, Stefanska B, Stephens GJ, Teixeira MM, Vergnolle N and Ahluwalia A (2022). Planning experiments: Updated guidance on experimental design and analysis and their reporting III. Wiley British Journal of Pharmacology vol. 179, (15) 3907-3913. Spitschan M, Santhi N, Ahluwalia A, Fischer D, Hunt L, Karp NA, Lévi F, Pineda-Torra I, Vidafar P and White R (2022). Sex differences and sex bias in human circadian and sleep physiology research. eLife eLife vol. 11, Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Moreira SAM, Rathod K, Chen J, Bubb K, Colas R, Khambata RS, Dalli J and Ahluwalia A (2022). 20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin. Wiley British Journal of Pharmacology vol. 179, (7) 1450-1469. 2021
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S, Dalby MC, Malik IS, Whitbread M, Firoozi S, Bogle R, Redwood S, Cooper J, Gupta A, Lansky A, Wragg A, Mathur A and Ahluwalia A (2021). The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction. Am J Cardiovasc Dis vol. 11, (5) 659-678. Maffia P, Antoniades C, Ahluwalia A and Cirino G (2021). Molecular imaging—The first visual themed issue published in the British Journal of Pharmacology. Wiley British Journal of Pharmacology vol. 178, (21) 4213-4215. Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V and Ahluwalia A (2021). Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers. Oxford University Press (OUP) European Heart Journal vol. 42, (Supplement_1) Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A, Nuredini G, Godec T, Kapil V and Ahluwalia A (2021). Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation. Oxford University Press (OUP) European Heart Journal vol. 42, (Supplement_1) Primus C, Masucci M, Whitear C, Moreira SAM, Kumar NA, Chhetri I, Rathod KS, Khambata R, Kapil V and Ahluwalia A (2021). A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate. Oxford University Press (OUP) European Heart Journal vol. 42, (Supplement_1) Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP, Filomena F, Nuredini G, Ibrahim AS, Khambata RS, Gupta AK, Moon JC, Kapil V and Ahluwalia A (2021). Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide. Wiley British Journal of Pharmacology vol. 179, (20) 4757-4777. Beirne A-M, Rathod KS, Castle E, Andiapen M, Richards A, Bellin A, Hammond V, Godec T, Moon JC, Davies C, Bourantas CV, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Jones DA (2021). The BYPASS-CTCA Study: the value of Computed Tomography Cardiac Angiography (CTCA) in improving patient-related outcomes in patients with previous bypass operation undergoing invasive coronary angiography: Study Protocol of a Randomised Controlled Trial. AME Publishing Company Annals of Translational Medicine Wang J, Mei F, Bai L, Zhou S, Liu D, Yao L, Ahluwalia A, Ghiladi RA, Su L, Shu T, Gong M, Wang X, Zhu L, Cai K and Zhang X (2021). Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications? Elsevier Free Radical Biology and Medicine vol. 175, 216-225. George CH, Alexander SPH, Cirino G, Insel PA, Izzo AA, Ji Y, Kendall DA, Panettieri RA, Patel HH, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2021). Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP). Wiley British Journal of Pharmacology vol. 178, (18) 3605-3610. Beirne A-M, Mitchelmore O, Palma S, Andiapen M, Rathod KS, Hammond V, Bellin A, Cooper J, Wright P, Antoniou S, Yaqoob MM, Naci H, Mathur A, Ahluwalia A and Jones DA (2021). NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes. SAGE Publications Journal of Cardiovascular Pharmacology and Therapeutics vol. 26, (4) 303-309. 2020
Kelham M, Choudry FA, Hamshere S, Beirne A-M, Rathod KS, Baumbach A, Ahluwalia A, Mathur A and Jones DA (2020). Therapeutic Implications of COVID-19 for the Interventional Cardiologist. SAGE Publications Journal of Cardiovascular Pharmacology and Therapeutics vol. 26, (3) 203-216. Shabbir A and Ahluwalia A (2020). Second wave and second opportunity: capitalizing on cardiovascular research activity during the COVID-19 pandemic. Oxford University Press (OUP) European Heart Journal - Quality of Care and Clinical Outcomes vol. 7, (3) 321-322. Shabbir A, Rathod KS, Khambata RS and Ahluwalia A (2020). Sex Differences in the Inflammatory Response: Pharmacological Opportunities for Therapeutics for Coronary Artery Disease. Annual Reviews The Annual Review of Pharmacology and Toxicology vol. 61, (1) 1-27. Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research. Springer Nature BMC Veterinary Research vol. 16, (1) Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2020). ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020. Wiley British Journal of Pharmacology vol. 177, (16) 3611-3616. du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. Wiley The Journal of Physiology vol. 598, (18) 3793-3801. du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0. Public Library of Science (PLoS) PLOS Biology vol. 18, (7) du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2020). The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*. SAGE Publications Cerebrovascular and Brain Metabolism Reviews vol. 40, (9) 1769-1777. Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM and Ahluwalia A (2020). The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway. Pharmacological reviews vol. 72, (3) 692-766. du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Wuerbel H (2020). The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. Portico BMJ Open Science vol. 4, (1) Cirino G and Ahluwalia A (2020). The many mechanisms of action of Chloroquine: to use or not to use (in COVID‐19) that is the question. Wiley British Journal of Pharmacology vol. 177, (15) 3361-3362. Izzo AA, Teixeira M, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Ji Y, Kendall DA, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G and Ahluwalia A (2020). A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research. Wiley British Journal of Pharmacology vol. 177, (10) 2169-2178. Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A, Moon JC, Kapil V and Ahluwalia A (2020). Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: Protocol of the NITRATE-TOD study in the UK. BMJ Journals BMJ Open vol. 10, (1) 2019
Dreyer G, Kieswich J, Harwood S, Ahluwalia A and Yaqoob MM (2019). Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia. Portland Press Bioscience Reports vol. 39, (12) George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2019). The BJP expects authors to share data. Wiley British Journal of Pharmacology vol. 176, (24) 4595-4598. Ingram JR and Ahluwalia A (2019). The pharmacology of itch. Wiley British Journal of Pharmacology vol. 176, (23) 4419-4420. Ingram JR and Ahluwalia A (2019). The pharmacology of itch. Wiley British Journal of Dermatology Jones DA, Mathur A and Ahluwalia A (2019). Letter by Jones et al regarding article, “Optimized treatment of ST-elevation myocardial infarction”. American Heart Association Circulation Research vol. 125, (6) E29-E29. Docherty JR, Stanford SC, Panettieri RA, Alexander SPH, Cirino G, George CH, Hoyer D, Izzo AA, Ji Y, Lilley E, Sobey CG, Stanley P, Stefanska B, Stephens G, Teixeira M and Ahluwalia A (2019). Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable. Wiley British Journal of Pharmacology vol. 176, (21) 4081-4086. du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2019). Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019. Cold Spring Harbor Laboratory du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lidster K, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H (2019). The ARRIVE guidelines 2019: updated guidelines for reporting animal research. Cold Spring Harbor Laboratory Jones DA, Rathod KS, Williamson A, Mand K, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A (2019). Corrigendum to “The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction” [Int. J. Cardiol. 266 (2018) 1–6]. Elsevier International Journal of Cardiology vol. 292, Guzik TJ and Ahluwalia A (2019). Plan S: in Service or Disservice to Society? Oxford University Press (OUP) European Heart Journal vol. 40, (12) 949-952. Guzik TJ and Ahluwalia A (2019). Plan S: In service or disservice to society? Wiley British Journal of Pharmacology vol. 176, (6) 753-756. 2018
Jones DA, Rathod KS, Williamson A, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A (2018). The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction. Elsevier International Journal of Cardiology vol. 266, 1-6. Curtis MJ, Ashton JC, Moon LDF and Ahluwalia A (2018). Clarification of the basis for the selection of requirements for publication in the British Journal of Pharmacology. Wiley British Journal of Pharmacology vol. 175, (18) 3633-3635. AHLUWALIA A, JONES D and MATHUR A (2018). Sodium Nitrite-Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis. SAGE Publications Journal of Cardiovascular Pharmacology and Therapeutics Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A and Ahluwalia A (2018). P2564Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis. Oxford University Press (OUP) European Heart Journal vol. 39, (suppl_1) Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, Watson DS, Barnes MR, Wade WG and Ahluwalia A (2018). Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria. Elsevier Free Radical Biology and Medicine vol. 126, 113-121. Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C and Ahluwalia A (2018). Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis. FASEB J fj201701303-fj201701303. Ahluwalia A and Cirino G (2018). Launch of mini‐reviews in hot topics. Wiley British Journal of Pharmacology vol. 175, (13) 2537-2537. du Sert NP, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Howells DW, Karp NA, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H and Holgate ST (2018). Revision of the ARRIVE guidelines: rationale and scope. Portico BMJ Open Science vol. 2, (1) Yellon DM, He Z, Khambata R, Ahluwalia A and Davidson SM (2018). The GTN patch: a simple and effective new approach to cardioprotection? Springer Nature Basic Research in Cardiology vol. 113, (3) Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Stanford SC, Teixeira MM, Wonnacott S and Ahluwalia A (2018). Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers. Wiley British Journal of Pharmacology vol. 175, (7) 987-993. AHLUWALIA A (2018). Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology. Wiley British Journal of Pharmacology vol. 175, 407-411. 2017
Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A, Alam S, Brown M, Henderson H, de Leeuw W, Marsh J, Moher D, van Oort E, Rawle F, Riederer BM, Sanchez-Morgado J, Sena ES, Struthers C, Westmore M, Avey MT, Kalman R, O’Connor A, Sargeant J, Petrie A and Smith A (2017). Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting. Springer Nature BMC Veterinary Research vol. 13, (1) Kapil V (2017). Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017. BMC Pharmacol Toxicol vol. 18, (Suppl 1) 64-64. Ahluwalia A, Jones MK, Hoa N and Tarnawski AS (2017). NGF protects endothelial cells from indomethacin-induced injury through activation of mitochondria and upregulation of IGF-1. Elsevier Cellular Signalling vol. 40, 22-29. Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A and Jones DA (2017). Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials. Sage Journals JRSM Cardiovasc Dis vol. 6, 20480040177-20480040177. George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Wonnacott S and Ahluwalia A (2017). Updating the guidelines for data transparency in the British Journal of Pharmacology – data sharing and the use of scatter plots instead of bar charts. Wiley British Journal of Pharmacology vol. 174, (17) 2801-2804. Campo G, Pavasini R, Morciano G, Lincoff MA, Gibson MC, Kitakaze M, Lonborg J, Ahluwalia A, Ishii H, Frenneaux M, Ovize M, Galvani M, Atar D, Ibanez B, Cerisano G, Biscaglia S, Neil BJ, Asakura M, Engstrom T, Jones DA, Dawson D, Ferrari R, Pinton P and Ottani F (2017). Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention. Elsevier Data in Brief vol. 14, 197-205. Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Cutillas PR, Ahluwalia A and Corder R (2017). Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1. Sci Rep vol. 7, (1) 4956-4956. Campo G, Pavasini R, Morciano G, Lincoff AM, Gibson CM, Kitakaze M, Lonborg J, Ahluwalia A, Ishii H, Frenneaux M, Ovize M, Galvani M, Atar D, Ibanez B, Cerisano G, Biscaglia S, Neil BJ, Asakura M, Engstrom T, Jones DA, Dawson D, Ferrari R, Pinton P and Ottani F (2017). Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials. Elsevier International Journal of Cardiology vol. 244, 59-66. AHLUWALIA A (2017). The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque. National Academy of Sciences Proceedings of the National Academy of Sciences of USA Jones DA, Rathod KS and Ahluwalia A (2017). Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation. Nitric Oxide: Biology and Pathobiology: Third Edition Jones DA, Rathod KS and Ahluwalia A (2017). Chapter 15 Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation. Nitric Oxide Elsevier 2016
Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK, Deaner A, Poulter N, Caulfield MJ, Mathur A and Ahluwalia A (2016). Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study. BMJ BMJ Open vol. 6, (12) AHLUWALIA A (2016). Accelerated resolution underlies sex differences in the inflammatory response in human. American Society for Clinical Investigation Journal of Clinical Investigation vol. 127, (1) 169-182. Ahluwalia A, Jones MK, Brzozowski T and Tarnawski AS (2016). Nerve growth factor is critical requirement for in vitro angiogenesis in gastric endothelial cells. American Physiological Society AJP Gastrointestinal and Liver Physiology vol. 311, (5) g981-g987. Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A and Ahluwalia A (2016). Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention. BMJ Publishing Group Heart Hoa NT, Ge L, Martini F, Chau V, Ahluwalia A, Kruse CA and Jadus MR (2016). Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy. Taylor & Francis Expert Opinion on Therapeutic Targets vol. 20, (10) 1155-1167. Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim‐Shapiro DB, Lajous M, Larsen FJ, Lefer DJ, McClure LA, Nolan BT, Pluta R, Schechter A, Wang C, Ward MH and Harman JL (2016). Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop. Wolters Kluwer Journal of the American Heart Association vol. 5, (7) Samarasena JB, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ and Tarnawski AS (2016). In vivo imaging of porcine gastric enteric nervous system using confocal laser endomicroscopy &molecular neuronal probe. Wiley Journal of Gastroenterology and Hepatology vol. 31, (4) 802-807. Ivanova E, Coroiu A, Ahluwalia A, Alexandrov E and Lafreniere KD (2016). Preliminary Findings on the Association Between Symptoms of Depression and Adherence to Antiretroviral Therapy in Individuals Born Inside Versus Outside of Canada. Wolters Kluwer Journal of the Association of Nurses in AIDS Care vol. 27, (4) 512-523. Aguinaldo JP, Ahluwalia A, Hambly K, Koornstra J, Rankin B and Roesslein K (2016). Needs and Supports in Transitional Housing for People Living with HIV/AIDS in Ontario, Canada. Taylor & Francis Journal of Social Service Research vol. 42, (3) 352-362. Gee LC and Ahluwalia A (2016). Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence. Springer Nature Current Hypertension Reports vol. 18, (2) Rathod KS, Velmurugan S and Ahluwalia A (2016). A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer? Molecular Nutrition and Food Research vol. 60, (1) 185-202. 2015
Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V, Chowdhury TA, Curtis M, Kuhnle GG, Wade WG and Ahluwalia A (2015). Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study 1–3. Elsevier American Journal of Clinical Nutrition vol. 103, (1) 25-38. Fernandes D, Khambata R and Ahluwalia A (2015). Abstract 10110: Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis. Wolters Kluwer Circulation vol. 132, (suppl_3) Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM and Thorpe CM (2015). Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. American Society for Microbiology Infection and Immunity vol. 84, (1) 138-148. Rathod KS, Velmurugan S and Ahluwalia A (2015). A ‘green’ diet‐based approach to cardiovascular health? Is inorganic nitrate the answer? Wiley Molecular Nutrition & Food Research vol. 60, (1) 185-202. Samarasena JB, Tarnawski AS, Ahluwalia A, Shinoura S, Choi KD, Lee JG and Chang KJ (2015). EUS-guided in vivo imaging of the porcine esophageal enteric nervous system by using needle-based confocal laser endomicroscopy. Elsevier Gastrointestinal Endoscopy vol. 82, (6) 1116-1120. (2015). Erratum. Wiley British Journal of Pharmacology vol. 172, (18) 4600-4600. Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SPA, Giembycz MA, Gilchrist A, Hoyer D, Insel PA, Izzo AA, Lawrence AJ, MacEwan DJ, Moon LDF, Wonnacott S, Weston AH and McGrath JC (2015). Experimental design and analysis and their reporting: new guidance for publication in BJP. Wiley British Journal of Pharmacology vol. 172, (14) 3461-3471. Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2015). Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)). Free Radical Biology and Medicine vol. 84, Tolstanova G, Deng X, Ahluwalia A, Paunovic B, Prysiazhniuk A, Ostapchenko L, Tarnawski A, Sandor Z and Szabo S (2015). Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease. Springer Nature Digestive Diseases and Sciences vol. 60, (10) 2963-2975. Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2015). Erratum to “Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex” [Free Radic. Biol. Med. 65 (2013) 1521–1532]. Elsevier Free Radical Biology and Medicine vol. 84, Khambata RS, Ghosh SM and Ahluwalia A (2015). “Repurposing” of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension. Mary Ann Liebert Antioxidants & Redox Signaling vol. 23, (4) 340-353. Lara J, Ashor AW, Oggioni C, Ahluwalia A, Mathers JC and Siervo M (2015). Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis. Springer Nature European Journal of Nutrition vol. 55, (2) 451-459. Macé V, Ahluwalia A, Coron E, Le Rhun M, Boureille A, Bossard C, Mosnier J, Matysiak‐Budnik T and Tarnawski AS (2015). Confocal laser endomicroscopy: A new gold standard for the assessment of mucosal healing in ulcerative colitis. Wiley Journal of Gastroenterology and Hepatology vol. 30, (S1) 85-92. Kapil V, Khambata RS, Robertson A, Caulfield MJ and Ahluwalia A (2015). Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study. Lippincott Williams and Wilkins Hypertension vol. 65, (2) 320-327. Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, Van Eijl S, Webb AJ, Westwood MA, Parmar MK, Mathur A and Ahluwalia A (2015). Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction. Circulation Research vol. 116, (3) 437-447. 2014
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, van Eijl S, Webb AJ, Westwood MA, Parmar MK, Mathur A and Ahluwalia A (2014). Randomized Phase 2 Trial of Intracoronary Nitrite During Acute Myocardial Infarction. Wolters Kluwer Circulation Research vol. 116, (3) 437-447. Tarnawski AS, Ahluwalia A and Jones MK (2014). Angiogenesis in gastric mucosa: An important component of gastric erosion and ulcer healing and its impairment in aging. Wiley Journal of Gastroenterology and Hepatology vol. 29, (S4) 112-123. Kapil V, Khambata RS, Robertson A, Caulfield MJ and Ahluwalia A (2014). Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients. Wolters Kluwer Hypertension vol. 65, (2) 320-327. Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T and Ahluwalia A (2014). P200 Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia. Elsevier Nitric Oxide vol. 42, Rathod K, Ghosh S, Khambata R and Ahluwalia A (2014). P175 Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity. Elsevier Nitric Oxide vol. 42, Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood MA, Webb AJ, Mathur A and Ahluwalia A (2014). P141 The safety and efficacy of intra-coronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): A single centre, randomised, double-blind controlled trial. Elsevier Nitric Oxide vol. 42, 127-128. Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock A-S, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A and Hobbs AJ (2014). Endothelial C-type natriuretic peptide maintains vascular homeostasis. J Clin Invest vol. 124, (9) 4039-4051. Ahluwalia A, Baatar D, Jones MK and Tarnawski AS (2014). Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB. American Physiological Society AJP Gastrointestinal and Liver Physiology vol. 307, (6) g602-g610. Kapil V, Weitzberg E, Lundberg JO and Ahluwalia A (2014). Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health. Nitric Oxide vol. 38, 45-57. Kapil V, Weitzberg E, Lundberg JO and Ahluwalia A (2014). Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health. Nitric Oxide - Biology and Chemistry vol. 38, (1) 45-57. Khomenko T, Deng X, Ahluwalia A, Tarnawski A, Patel KN, Sandor Z and Szabo S (2014). STAT3 and Importins Are Novel Mediators of Early Molecular and Cellular Responses in Experimental Duodenal Ulceration. Springer Nature Digestive Diseases and Sciences vol. 59, (2) 297-306. Tarnawski AS, Ahluwalia A and Jones MK (2014). Increased susceptibility of aging gastric mucosa to injury: The mechanisms and clinical implications. Baishideng Publishing Group World Journal of Gastroenterology vol. 20, (16) 4467-4482. Ahluwalia A, Jones MK, Matysiak-Budnik T and Tarnawski AS (2014). VEGF and colon cancer growth beyond angiogenesis: does VEGF directly mediate colon cancer growth via a non-angiogenic mechanism? Bentham Science Publishers Current Pharmaceutical Design vol. 20, (7) 1041-1044. 2013
Ahluwalia A, Jones MK and Tarnawski AS (2013). Key role of endothelial importin-α in VEGF expression and gastric angiogenesis: novel insight into aging gastropathy. American Physiological Society AJP Gastrointestinal and Liver Physiology vol. 306, (4) g338-g345. Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2013). Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex. Free Radic Biol Med vol. 65, 1521-1532. Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAI, Jegard J, Montoya A, Cutillas P, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Ahluwalia A and Corder R (2013). Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene. Elsevier Life Sciences vol. 93, (25-26) Bubb KJ, Wen H, Panayiotou CM, Finsterbusch M, Khan FJ, Chan MV, Priestley JV, Baker MD and Ahluwalia A (2013). Activation of neuronal transient receptor potential vanilloid 1 channel underlies 20-hydroxyeicosatetraenoic acid-induced vasoactivity: role for protein kinase A. Hypertension vol. 62, (2) 426-433. Ahluwalia A, Jones MK, Szabo S and Tarnawski AS (2013). Aberrant, ectopic expression of VEGF and VEGF receptors 1 and 2 in malignant colonic epithelial cells. Implications for these cells growth via an autocrine mechanism. Elsevier Biochemical and Biophysical Research Communications vol. 437, (4) 515-520. Ahluwalia A, Jones MK, Deng X, Sandor Z, Szabo S and Tarnawski AS (2013). An imbalance between VEGF and endostatin underlies impaired angiogenesis in gastric mucosa of aging rats. American Physiological Society AJP Gastrointestinal and Liver Physiology vol. 305, (4) g325-g332. Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S, Yousuf M, Benjamin N, Webb AJ, Caulfield MJ, Hobbs AJ and Ahluwalia A (2013). Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential. Hypertension vol. 61, (5) 1091-1102. Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E and Ahluwalia A (2013). Physiological role for nitrate-reducing oral bacteria in blood pressure control. Free Radic Biol Med vol. 55, 93-100. Ahluwalia A and Hobbs AJ (2013). Letter by Ahluwalia and Hobbs Regarding Article, Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics. CIRCULATION vol. 127, (2) E275-E275. Jones DA, Andiapen M, Van-Eijl TJA, Webb AJ, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A (2013). The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial. BMJ Open vol. 3, (4) Rousselle A, Qadri F, Leukel L, Yilmaz R, Fontaine J-F, Sihn G, Bader M, Ahluwalia A and Duchene J (2013). CXCL5 limits macrophage foam cell formation in atherosclerosis. JOURNAL OF CLINICAL INVESTIGATION vol. 123, (3) 1343-1347. Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A (2013). Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex. Free Radical Biology and Medicine vol. 65, 1521-1532. 2012
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P, Hartley O, Ahluwalia A and Corder R (2012). Abstract 18898: Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements. Wolters Kluwer Circulation vol. 126, (suppl_21) Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS and Ahluwalia A (2012). Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation. Br J Pharmacol vol. 167, (4) 805-817. Bubb KJ, Khambata RS and Ahluwalia A (2012). Sexual dimorphism in rodent models of hypertension and atherosclerosis. Br J Pharmacol vol. 167, (2) 298-312. Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A and Hobbs AJ (2012). Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase. Circulation vol. 125, (23) 2922-2932. Bahra M, Kapil V, Pearl V, Ghosh S and Ahluwalia A (2012). Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers. Nitric Oxide vol. 26, (4) 197-202. Wen H, Östman J, Bubb KJ, Panayiotou C, Priestley JV, Baker MD and Ahluwalia A (2012). 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel. J Biol Chem vol. 287, (17) 13868-13876. Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD, Perretti M, Ahluwalia A, Priestley JV, Chavakis T, Imhof BA, Feltri ML and Nourshargh S (2012). Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J vol. 26, (3) 1064-1076. Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P, Hartley O, Ahluwalia A and Corder R (2012). Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements. CIRCULATION vol. 126, (21) Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V and Ahluwalia A (2012). Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP. CIRCULATION vol. 126, (21) Moyes AJ, Khambata RS, Ahluwalia A and Hobbs AJ (2012). Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide. CIRCULATION vol. 126, (21) Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV, Magun BE and Jandhyala DM (2012). Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib. Frontiers Frontiers in Cellular and Infection Microbiology vol. 2, 2011
Duchene J and Ahluwalia A (2011). Kallikrein-kinin system in inflammation. Duchene J and Ahluwalia A (2011). 16 Kallikrein-kinin system in infl ammation. Kinins De Gruyter Paunovic B, Deng X, Khomenko T, Ahluwalia A, Tolstanova G, Tarnawski A, Szabo S and Sandor Z (2011). Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats. Elsevier Journal of Pharmacology and Experimental Therapeutics vol. 339, (2) 430-437. Florkiewicz RZ, Ahluwalia A, Sandor Z, Szabo S and Tarnawski AS (2011). Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons. Elsevier Biochemical and Biophysical Research Communications vol. 409, (3) 494-499. Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ and Ahluwalia A (2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol vol. 31, (5) 1075-1083. Monette LE, Rourke SB, Gibson K, Bekele TM, Tucker R, Greene S, Sobota M, Koornstra J, Byers S, Marks E, Bacon J, Watson JR, Hwang SW, Ahluwalia A, Dunn JR, Guenter D, Hambly K, Bhuiyan S and Positive Spaces Healthy Places Team (2011). Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/AIDS in Ontario: Results From the Positive Spaces, Healthy Places Study. Springer Nature Canadian Journal of Public Health vol. 102, (3) 215-219. Kapil V, Benjamin N, Hobbs A and Ahluwalia A (2011). Response to Inorganic Nitrate for Blood Pressure Lowering? HYPERTENSION vol. 57, (2) E3-E3. Rourke SB, Sobota M, Tucker R, Bekele T, Gibson K, Greene S, Price C, Koornstra JJJ, Monette L, Byers S, Watson J, Hwang SW, Guenter D, Dunn J, Ahluwalia A, Wilson MG and Bacon J (2011). Social determinants of health associated with hepatitis C co-infection among people living with HIV: results from the Positive Spaces, Healthy Places study. Open Medicine vol. 5, (3) e120-e131. 2010
Kapil V, Webb AJ and Ahluwalia A (2010). Inorganic nitrate and the cardiovascular system. Heart vol. 96, (21) 1703-1709. Yamashiro K, Milsom AB, Duchene J, Panayiotou C, Urabe T, Hattori N and Ahluwalia A (2010). Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice. J Cereb Blood Flow Metab vol. 30, (8) 1494-1503. Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N, Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ and Ahluwalia A (2010). Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension vol. 56, (2) 274-281. Tarnawski AS, Pai R, Tanigawa T, Matysiak-Budnik T and Ahluwalia A (2010). PTEN silencing reverses aging-related impairment of angiogenesis in microvascular endothelial cells. Elsevier Biochemical and Biophysical Research Communications vol. 394, (2) 291-296. Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ, Cuzzocrea S, Hobbs AJ, Thiemermann C and Ahluwalia A (2010). Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice. NITRIC OXIDE-BIOL CH vol. 22, (2) 141-148. (2010). A Role of Matrix Metalloproteinase-8 in Atherosclerosis: Correction. Wolters Kluwer Circulation Research vol. 106, (1) WEBB A, Webb A and Ahluwalia A (2010). Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System. Nitric Oxide Biology and Pathobiology , Editors: Ignarro LJ. Academic Press Webb A and Ahluwalia A (2010). Chapter 17 Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System. Nitric Oxide Elsevier Webb AJ and Ahluwalia A (2010). Mechanisms of nitrite reduction in ischemia in the cardiovascular system. Nitric Oxide: Biology and pathobiology , Editors: Ignarro L. Elsevier 2009
Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, Kim-Shapiro DB, Kozlov AV, Lancaster JR, Lefer DJ, McColl K, McCurry K, Patel RP, Petersson J, Rassaf T, Reutov VP, Richter-Addo GB, Schechter A, Shiva S, Tsuchiya K and van Faassen EE (2009). Nitrate and nitrite in biology, nutrition and therapeutics. NAT CHEM BIOL vol. 5, (12) 865-869. Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P, Marrelli A, Pitzalis C, Cipollone F, Schanstra J, Bascands J-L, Hobbs AJ, Perretti M and Ahluwalia A (2009). Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis. Arterioscler Thromb Vasc Biol vol. 29, (11) 1757-1763. Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung K-Y, Xiao Q, Scotland RS, Hodgkinson CP, Smith K, Willeit J, López-Otín C, Simpson IA, Kiechl S, Ahluwalia A, Xu Q and Ye S (2009). A role of matrix metalloproteinase-8 in atherosclerosis. Circ Res vol. 105, (9) 921-929. Greene S, Ahluwalia A, Watson J, Tucker R, Rourke SB, Koornstra J, Sobota M, Monette L and Byers S (2009). Between skepticism and empowerment: the experiences of peer research assistants in HIV/AIDS, housing and homelessness community‐based research. Taylor & Francis International Journal of Social Research Methodology vol. 12, (4) 361-373. Greene S, Tucker R, Rourke SB, Monette L, Koornstra J, Sobota M, Byers S, Hwang S, Dunn J, Guenter D, Ahluwalia A and Watson J (2009). “Under My Umbrella”: The housing experiences of HIV positive parents who live with and care for their children in Ontario. Springer Nature Archives of Women's Mental Health vol. 13, (3) 223-232. Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A and Ahluwalia A (2009). BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE. BASIC CLIN PHARMACOL vol. 105, 31-31. Okorie M, Akram F, Loukogeorgakis S, Webb A, Deanfield J, Benjamin N, Hobbs A, MacAllister R and Ahluwalia A (2009). ORAL INORGANIC NITRATE PROTECTS AGAINST ENDOTHELIAL ISCHAEMIA-REPERFUSION INJURY IN HUMANS. BASIC CLIN PHARMACOL vol. 105, 26-26. Duchene J and Ahluwalia A (2009). The kinin B(1) receptor and inflammation: new therapeutic target for cardiovascular disease. Curr Opin Pharmacol vol. 9, (2) 125-131. Hobbs AJ, Gane P, Lumsden N, Nobles M, Rebstock A-S, Simone M, Villar I, Worthington R, Xiao F, Ahluwalia A and Selwood D (2009). Design and development of novel non-peptide agonists at natriuretic peptide receptor-C. FASEB JOURNAL vol. 23, Klein J, Gonzalez J, Duchene J, Esposito L, Pradere JP, Neau E, Delage C, Calise D, Ahluwalia A, Carayon P, Pesquero JB, Bader M, Schanstra JP and Bascands JL (2009). Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy. FASEB J vol. 23, (1) 134-142. 2008
Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, Szabo S and Sandor Z (2008). Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF. Elsevier Journal of Pharmacology and Experimental Therapeutics vol. 328, (3) 749-757. Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FMJ, Perrett D, Raimondo C, Khoshbin E, Ahmed Z, Uppal R, Benjamin N, Hobbs AJ and Ahluwalia A (2008). Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase. Circ Res vol. 103, (9) 957-964. Villar IC, Hobbs AJ and Ahluwalia A (2008). Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. J ENDOCRINOL vol. 197, (3) 447-462. Jandhyala DM, Ahluwalia A, Obrig T and Thorpe CM (2008). ZAK: a MAP3Kinase that transduces Shiga toxin‐ and ricin‐induced proinflammatory cytokine expression. Hindawi Cellular Microbiology vol. 10, (7) 1468-1477. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A (2008). Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. HYPERTENSION vol. 51, (3) 784-790. Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin B, Macallister R, Hobbs A and Abluwalia A (2008). Acute blood pressure lowering and vasoprotective effects of dietary nitrate. FASEB JOURNAL vol. 22, Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A (2008). Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. American Heart Association Hypertension vol. 51, 784-790. 2007
Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M and Ahluwalia A (2007). A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5. J Immunol vol. 179, (7) 4849-4856. Sexton A, McDonald M, Cayla C, Thiemermann C and Ahluwalia A (2007). 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1. FASEB J vol. 21, (11) 2695-2703. Tarnawski A, Pai R, Deng X, Ahluwalia A, Khomenko T, Tanigawa T, Akahoshi T, Sandor Z and Szabo S (2007). Aging Gastropathy—Novel Mechanisms: Hypoxia, Up-regulation of Multifunctional Phosphatase PTEN, and Proapoptotic Factors. Elsevier Gastroenterology vol. 133, (6) 1938-1947.e1. Villar IC, Panayiotou CM, Sheraz A, Madhani M, Scotland RS, Nobles M, Kemp-Harper B, Ahluwalia A and Hobbs AJ (2007). Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor. CARDIOVASC RES vol. 74, (3) 515-525. Tripatara P, Patel NSA, Webb A, Rathod K, Lecomte FMJ, Mazzon E, Cuzzocrea S, Yaqoob MM, Ahluwalia A and Thiemermann C (2007). Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. J Am Soc Nephrol vol. 18, (2) 570-580. 2006
Villar IC, Ahluwalia A and Hobbs AJ (2006). Distinct pathways regulate endothelium derived hyperpolarising factor-mediated responses in rat mesenteric arteries. ACTA PHARMACOL SIN vol. 27, (9) 1276-1276. Villar IC, Francis S, Webb A, Hobbs AJ and Ahluwalia A (2006). Novel aspects of endothelium-dependent regulation of vascular tone. KIDNEY INT vol. 70, (5) 840-853. 2005
Scotland RS, Cohen M, Foster P, Lovell M, Mathur A, Ahluwalia A and Hobbs AJ (2005). C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression. P NATL ACAD SCI USA vol. 102, (40) 14452-14457. Webb A, Qureshi S, Benjamin N, Perrett D and Ahluwalia A (2005). Xanthine oxidase activity provides an alternative source of no during ischaemia from inorganic nitrite in rat blood vessels. BRIT J CLIN PHARMACO vol. 59, (5) 631-632. Ahluwalia A and Hobbs AJ (2005). Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor. TRENDS PHARMACOL SCI vol. 26, (3) 162-167. Vo PA, Lad B, Tomlinson JAP, Francis S and Ahluwalia A (2005). autoregulatory role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function. J Biol Chem vol. 280, (8) 7236-7243. Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, Hobbs AJ and Ahluwalia A (2005). Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice - Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. CIRCULATION vol. 111, (6) 796-803. Scotland RS, Ahluwalia A and Hobbs AJ (2005). C-type natniuretic peptide in vascular physiology and disease. PHARMACOL THERAPEUT vol. 105, (2) 85-93. Ahluwalia A, SCOTLAND RS, Andersen J, Chauhan S, Moncada S, Nilsson H, Hobbs AJ and Madhani M (2005). Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo. Circulation vol. 111, (6) 796-803. AHLUWALIA A, Scotland RS, Hobbs AJ, Moncada S, Chauhan S, Andresen J, Nilsson H and Madhani M (2005). Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo. Circulation vol. 111, (6) 796-803. AHLUWALIA A, Francis S, Tomlinson JA, Lad B and Vo PA (2005). role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function. J Biol Chem vol. 25280, (8) 7236-7243. AHLUWALIA A, Mathur A, Lovell M, Hobbs AJ, Cohen M and Scotland RS (2005). C-type natriuretic peptide inhibits leukocyte recruitment and platelet aggregation. PNAS vol. 102, (40) 14452-14457. 2004
Scotland RS, Chauhan S, Davis C, De Felipe C, Hunt S, Kabir J, Kotsonis P, Oh U and Ahluwalia A (2004). Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction. Circ Res vol. 95, (10) 1027-1034. AHLUWALIA A, Oh U, Kabir J, De Felipe C, Chauhan S, Scotland RS, Davis C, Hunt S and Kotsonis P (2004). Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction. Circ Res vol. 95, (10) 1027-1034. Chauhan SD, Hobbs AJ and Ahluwalia A (2004). C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor. Int J Biochem Cell Biol vol. 36, (10) 1878-1881. Webb A, Bond R, McLean P, Uppal R, Benjamin N and Ahluwalia A (2004). Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. P NATL ACAD SCI USA vol. 101, (37) 13683-13688. Hobbs A, Foster P, Prescott C, Scotland R and Ahluwalia A (2004). Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury - Novel cardioprotective role for endothelium-derived C-type natriuretic peptide. CIRCULATION vol. 110, (10) 1231-1235. Ahluwalia A, MacAllister RJ and Hobbs AJ (2004). Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms. Basic Res Cardiol vol. 99, (2) 83-89. AHLUWALIA A (2004). DICHOTOMOUS ROLE OF THE ENDOTHELIUM IN LPS-INDUCED ENDOTHELIAL DYSFUNCTION. Wolters Kluwer Shock vol. 21, (Supplement) Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S and Hobbs AJ (2004). Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. P NATL ACAD SCI USA vol. 101, (5) 1386-1391. AHLUWALIA A, Sarkar D, Aston D and McLean P (2004). Protease-activated receptor (PAR)-2 causes endothelium-dependant, NO-independant coronary vasodilatation: involvement of C-fibres and EDHF. Circ. Res vol. 90, 465-472. AHLUWALIA A, Hobbs A, Prescott C, Scotland R and Foster P (2004). Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide. Circulation vol. 110, (10) 1231-1235. Ahluwalia A, PERRETTI M, Mathur A, Moncada S, McLean PG, Hobbs AJ, Scotland RS and Foster P (2004). Inhibition of leukocyte-endothelial cell interactions by nitric oxide via a cGMP-mediated down-regulation of P-selectin expression. Proceedings of the National Academy of Sciences USA vol. 101, 1386-1391. 2003
Ahluwalia A (2003). To b'EET or not to b'EET? That is the question! Clin Sci (Lond) vol. 105, (4) 399-401. Chauhan SD, Nilsson H, Ahluwalia A and Hobbs AJ (2003). Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor. P NATL ACAD SCI USA vol. 100, (3) 1426-1431. AHLUWALIA A, Hobbs AJ, Seggara G, Chauhan SD, Vo PA and MacAllister RJ (2003). Protection against liposaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. Faseb J vol. 17, (6) 773-775. Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R and Ahluwalia A (2003). NO contributes to EDHF-like responses in rat small arteries: a role for NO stores. Cardiovasc Res vol. 57, (1) 207-216. 2002
Chauhan SD, MacAllister RJ, Hobbs AJ and Ahluwalia A (2002). Mechanisms underlying the vasorelaxant activity of C-type natriuretic peptide (CNP) in rat mesenteric resistance arteries. FASEB J vol. 16, (4) A572-A572. McLean P and Ahluwalia A (2002). Protease-activated receptor (PAR)-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia-reperfusion injury, involvement of lipoxygenase products, VR1 receptors and C-fibers. FASEB J vol. 16, (4) A569-A569. McLean PG, Aston D, Sarkar D and Ahluwalia A (2002). Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation - Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors, and C-fibers. CIRC RES vol. 90, (4) 465-472. Hesslinger C, Chen Z, Ahluwalia A, Selwood DL, Vallance P, Pfeilschifter J and Hingorani AD (2002). Regulation of GTP Cyclohydrolase I by Estrogen. Chemistry and Biology of Pteridines and Folates Springer Nature 2001
Scotland RS, Chauhan S, Vallance PJ and Ahluwalia A (2001). An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide. Hypertension vol. 38, (4) 833-839. Ahluwalia A (2001). Nepadutant Menarini Richerche. Curr Opin Investig Drugs vol. 2, (7) 919-922. Ahluwalia A, SCOTLAND RS, Vallance PJ and Chauhan S (2001). An EDHF-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of eNOS-derived nitric oxide. Hypertension vol. 38, (4) 833-839. 2000
McLean PG, Perretti M and Ahluwalia A (2000). Kinin B1 receptors and the cardiovascular system: regulation of expression and function. Oxford University Press (OUP) Cardiovascular Research vol. 48, (2) 194-210. McLean PG, Ahluwalia A and Perretti M (2000). Association between Kinin B1 Receptor Expression and Leukocyte Trafficking across Mouse Mesenteric Postcapillary Venules. Rockefeller University Press Journal of Experimental Medicine vol. 192, (3) 367-380. Scotland RS, Vallance PJT and Ahluwalia A (2000). Endogenous factors involved in regulation of tone of arterial vasa vasorum: implications for conduit vessel physiology. Oxford University Press (OUP) Cardiovascular Research vol. 46, (3) 403-411. PERRETTI M and AHLUWALIA A (2000). The Microcirculation and Inflammation: Site of Action for Glucocorticoids. Wiley Microcirculation vol. 7, (3) 147-161. Bogle RG, McLean PG, Ahluwalia A and Vallance P (2000). Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia. Wiley British Journal of Pharmacology vol. 130, (1) 118-124. McLean PG, Perretti M and Ahluwalia A (2000). Kinin B1 receptors as novel anti-inflammatory targets. Taylor & Francis Expert Opinion on Therapeutic Targets vol. 4, (2) 127-141. Chauhan SD, MacAllister RJ, Clapp LH and Ahluwalia A (2000). Evidence that no may contribute to EDHF-like responses in rat mesenteric and hepatic small arteries. BRITISH JOURNAL OF PHARMACOLOGY vol. 129, Ahluwalia A and Scotland R (2000). Activation of sensory C-fibres partially mediates the vascular myogenic response. FASEB JOURNAL vol. 14, (4) A143-A143. 1999
KAKUYAMA M, AHLUWALIA A, RODRIGO J and VALLANCE P (1999). Cholinergic Contraction Is Altered in nNOS Knockouts. American Thoracic Society American Journal of Respiratory and Critical Care Medicine vol. 160, (6) 2072-2078. Scotland R, Vallance P and Ahluwalia A (1999). Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology. Wiley British Journal of Pharmacology vol. 128, (6) 1229-1234. McLean PG, Perretti M and Ahluwalia A (1999). Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des‐Arg9bradykinin‐induced coronary vasodilation. Wiley British Journal of Pharmacology vol. 128, (2) 275-282. Ahluwalia A and Perretti M (1999). B1 receptors as a new inflammatory target. Could this B the 1? Elsevier Trends in Pharmacological Sciences vol. 20, (3) 100-104. Scotland R, Vallance P and Ahluwalia A (1999). On the regulation of tone in vasa vasorum. Oxford University Press (OUP) Cardiovascular Research vol. 41, (1) 237-245. McLean PG, Perretti M and Ahluwalia A (1999). The involvement of kinin B1 receptors in the hypotensive response to endotoxin in rats. BRITISH JOURNAL OF PHARMACOLOGY vol. 127, U62-U62. Varsani M, MacAllister R, Ahluwalia A and Marshall I (1999). Investigation of the α1 adrenoceptor subtype(s) mediating contraction in the human internal mammary artery. BRITISH JOURNAL OF PHARMACOLOGY vol. 127, 1998
Ahluwalia A, De Felipe C, O'Brien J, Hunt SP and Perretti M (1998). Impaired IL‐1β‐induced neutrophil accumulation in tachykinin NK1 receptor knockout mice. Wiley British Journal of Pharmacology vol. 124, (6) 1013-1015. Ahluwalia A, Giuliani S, Scotland R and Maggi CA (1998). Ovalbumin‐induced neurogenic inflammation in the bladder of sensitized rats. Wiley British Journal of Pharmacology vol. 124, (1) 190-196. Ahluwalia A (1998). Topical glucocorticoids and the skin‐mechanisms of action: an update. Wiley Mediators of Inflammation vol. 7, (3) 183-193. Kakuyama M, Vallance P and Ahluwalia A (1998). Endothelium‐dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store. Wiley British Journal of Pharmacology vol. 123, (2) 310-316. McLean PG, Perretti M and Ahluwalia A (1998). Investigation of endotoxin-inducible B1 and constitutive B2 kinin receptors mediating coronary vasodilation in the rat isolated heart. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY vol. 358, (1) R335-R335. 1997
Ahluwalia A, Gokulan K, Nath I and Rao DN (1997). Modification of Delivery System Enhances MHC Nonrestricted Immunogenicity of V3 Loop Region of HIV‐1 gp120. Wiley Microbiology and Immunology vol. 41, (10) 779-784. Ahluwalia A and Vallance P (1997). Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins. Journal of Pharmacology and Experimental Therapeutics vol. 281, (1) 9-14. Ahluwalia A, Giuliani S and Maggi CA (1997). Allergic inflammation in the rat urinary bladder: Involvement of mast cells and C-fibres. BRITISH JOURNAL OF PHARMACOLOGY vol. 122, Ahluwalia A and Cellek S (1997). Regulation of the cardiovascular system by non-adrenergic non-chollnergic nerves. Wolters Kluwer Current Opinion in Nephrology & Hypertension vol. 6, (1) 74-79. Scotland RS, Vallance PJ and Ahluwalia A (1997). Comparison of vascular reactivity of porcine aorta and its vasa vasorum. CIRCULATION vol. 96, (8) 908-908. Kakuyama M, Vallance PJ and Ahluwalia A (1997). P-30 Non-adrenergic non-cholinergic relaxation of the rabbit mesenteric small artery: Involvement of NO. Elsevier Journal of Pharmacological Sciences vol. 75, 1996
Halpern SM, Ahluwalia A, Makunura CN and Jordan S (1996). Investigation of notalgia paraesthetica using laser Doppler velocimetry and immunohistochemistry before and after treatment with topical capsaicin. Wiley Journal of the European Academy of Dermatology and Venereology vol. 7, (3) 228-234. Ahluwalia A and Vallance P (1996). Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide. American Physiological Society American Journal of Physiology vol. 271, (3) h969-h976. Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK and Flower RJ (1996). Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1. Wiley British Journal of Pharmacology vol. 117, (6) 1145-1154. Ahluwalia A and Perretti M (1996). Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. The American Association of Immunologists The Journal of Immunology vol. 156, (1) 269-274. Ahluwalia A and Vallance PJ (1996). Reactivity of the vasa vasorum. CIRCULATION vol. 94, (8) 3443-3443. 1995
Ahluwalia A, Giuliani S and Maggi CA (1995). Demonstration of a ‘septide‐sensitive’ inflammatory response in rat skin. Wiley British Journal of Pharmacology vol. 116, (4) 2170-2174. Ahluwalia A, Newbold P, Brain SD and Flower RJ (1995). Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1. Elsevier European Journal of Pharmacology vol. 283, (1-3) 193-198. AHLUWALIA A, NEWBOLD P and FLOWER RJ (1995). TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1. BRITISH JOURNAL OF PHARMACOLOGY vol. 114, P61-P61. AHLUWALIA A, GIULIANI S and MAGGI CA (1995). DEMONSTRATION OF A SEPTIDE-SENSITIVE INFLAMMATORY RESPONSE IN RAT SKIN. BRITISH JOURNAL OF PHARMACOLOGY vol. 114, P41-P41. 1994
Ahluwalia A and Perretti M (1994). Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse. Elsevier European Journal of Pharmacology vol. 264, (3) 407-415. Ahluwalia A, Mohamed RW and Flower RJ (1994). Induction of lipocortin 1 by topical steroid in rat skin. Elsevier Biochemical Pharmacology vol. 48, (8) 1647-1654. Ahluwalia A, Maggi CA, Santicioli P, Lecci A and Giuliani S (1994). Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder. Wiley British Journal of Pharmacology vol. 111, (4) 1017-1022. Ahluwalia A and Perretti M (1994). Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors. Journal of Pharmacology and Experimental Therapeutics vol. 268, (3) 1526-1531. AHLUWALIA A and FLOWER RJ (1994). CHARACTERIZATION OF CAPSAICIN-INDUCED VASODILATION OF THE PERFUSED RABBIT EAR AND ITS MODULATION BY DEXAMETHASONE. BRITISH JOURNAL OF PHARMACOLOGY vol. 112, U104-U104. 1993
Perretti M, Ahluwalia A, Harris JG, Goulding NJ and Flower RJ (1993). Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody. The American Association of Immunologists The Journal of Immunology vol. 151, (8) 4306-4314. Perretti M, Ahluwalia A, Flower RJ and Manzini S (1993). Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors. Immunology vol. 80, (1) 73-77. Ahluwalia A and Flower RJ (1993). Investigations into the mechanism of vasoconstrictor action of the topical steroid betamethasone‐17‐valerate in the rat. Wiley British Journal of Pharmacology vol. 108, (2) 544-548. AHLUWALIA A, FLOWER RJ and PERRETTI M (1993). DUAL-ACTION OF PROSTAGLANDINS (PGS) IN THE MOUSE SKIN EDEMA TEST. BRITISH JOURNAL OF PHARMACOLOGY vol. 109, P5-P5. AHLUWALIA A and FLOWER RJ (1993). Topical betamethasone‐17‐valerate inhibits heat‐induced vasodilatation in man. Oxford University Press (OUP) British Journal of Dermatology vol. 128, (1) 45-48. 1992
Ahluwalia A, Peers SH and Flower RJ (1992). Steroid inhibition of oedema formation in the rat skin. Wiley British Journal of Pharmacology vol. 106, (3) 628-631. AHLUWALIA A and FLOWER RJ (1992). TOPICAL STEROIDS AND ACE INHIBITORS - A COMMON LINK. BRITISH JOURNAL OF PHARMACOLOGY vol. 106, P5-P5. Grants
QMUL 4th Intake 2024, 4 Year PhD Studentship (5th) SchemeAmrita Ahluwalia
£479,408 BHF British Heart Foundation (01-10-2024 - 30-09-2028)
Enhancing Cardiovascular cGMP to Target Hypertensive Heart Failure in FemalesAmrita Ahluwalia
£139,727 NHMRC National Health and Medical Research Council (Australia) (02-04-2024 - 01-04-2027)
QMUL 3rd intake, 2023 4-Year PhD Studentship (5th) SchemeAmrita Ahluwalia
£479,924 BHF British Heart Foundation (01-10-2023 - 30-09-2027)
QMUL 2nd intake 2022 - 4 Year PhD Studentship (5th) SchemeAmrita Ahluwalia
£447,561 BHF British Heart Foundation (01-10-2022 - 30-09-2026)
Randomised Control Trial: Cryoballoon/Radio frequency ablation of a trial fibrillation versus medical treatment for heart failureTreatmentAmrita Ahluwalia
£975,493 BHF British Heart Foundation (01-09-2022 - 28-02-2028)
Assessment of nitrite/nitrate in biological samplesAmrita Ahluwalia
£120,000 WHRL William Harvey Research Limited (01-07-2022 - 31-12-2025)
BHF 4 Year PhD Studentships (2021 - 2024 intakes)Amrita Ahluwalia
£444,465 BHF British Heart Foundation (01-10-2021 - 30-09-2025)
Therapeutic utility of targeting C-type natriuretic peptide to maintain endothelial integrity£334,632 MRC Medical Research Council (05-10-2020 - 31-07-2025)
A Multi Site, Placebo Controlled, Double Blind Randomised Clinical Trial Evaluating The Effectiveness Of Sodium Zirconium Cyclosilicate Versus Placebo To Enable Safe Optimisation Of RASi Therapy In Patients With Diabetic Kidney Disease QMAmrita Ahluwalia
£217,020 BH NHS Barts Health NHS (01-04-2022 - 30-09-2024)
BHF 4-Year PhD Studentship AwardAmrita Ahluwalia
£594,796 BHF British Heart Foundation (01-10-2020 - 30-09-2024)
BHF 4-Year PhD Studentship Award (3rd Intake 2019 OF 4th Scheme)Amrita Ahluwalia
£653,416 BHF British Heart Foundation (01-10-2019 - 30-09-2023)
Inorganic nitrate treatment reduces inflammation in humans: assessment of mechanismsAmrita Ahluwalia, Rob Krams, Federica Marelli-Berg and Jacqueline Cooper
£206,297 BHF British Heart Foundation (19-08-2019 - 18-02-2022)
TRP13/17 Effect of inorganic nitrate on contrast-induced nephropathy in patients undergoing coronary angiograph/ percutaneous coronary intervention for Acute Coronary Syndrome (ACS): A randomised single-centre, double-blind placebo-controlled trialAmrita Ahluwalia, Anthony Mathur and Daniel Jones
£144,825 HRUK Heart Research UK (25-10-2018 - 31-12-2022)
Assessment of the effects of nutritional extracts upon endothelial cell functionAmrita Ahluwalia
£95,939 WHRL William Harvey Research Limited (18-10-2018 - 31-12-2021)
BHF 4-Year PhD Studentship Award- 2nd intakeAmrita Ahluwalia
£652,264 BHF British Heart Foundation (01-10-2018 - 30-09-2022)
BHF 4-Year PhD Studentship AwardAmrita Ahluwalia
£692,452 BHF British Heart Foundation (01-10-2017 - 28-02-2022)
Delineating physiological and pathological regulatory roles for C-type natriuretic peptide in cardiac structure and function£817,911 BHF British Heart Foundation (01-10-2016 - 28-02-2022)
Creating global leadership in cardiovascular care, research and educationAmrita Ahluwalia
£10,276,879 Barts and the London Charity (01-07-2015 - 31-03-2024)