Prof Amrita Ahluwalia

Amrita Ahluwalia

Dean For Research Faculty of Medicine and Dentistry

The William Harvey Research Institute
Queen Mary University of London
www.qmul.ac.uk/whri/people/academic-staff/items/ahluwaliaamrita.html

Research

Sex differences, Nitrite/Nitrate/Nitric oxide, Xanthine oxidoreductase, inflammation, cardiovascular

Cardiovascular Models

Interests

Sex differences in drug action related to treatment of cardiovascular disease is neglected, however, most drugs removed for use by the FDA relate to adverse effects in women. I am interested in exploring sex differences using in vitro models.
Separately the enzyme xanthine oxidoreductase has been implicated in cardiovascular disease development. We have developed small molecules that target this enzyme and identified rare mutations that are linked with disease. Exploring drug action in genetic models in vitro is of interest.

Publications

solid heart iconPublications of specific relevance to Predictive <em>in vitro</em> Models

2024

CTCA Prior to Invasive Coronary Angiography in Patients With Previous Bypass Surgery: Patient-Related Outcomes, Imaging Resource Utilization, and Cardiac Events at 3 Years From the BYPASS-CTCA Trial
Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Learoyd AE, Forooghi N, Ramaseshan R, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Jones DA
Circulation Cardiovascular Interventions, Wolters Kluwer vol. 17 (12) 
25-11-2024
Potential Opportunities for Pharmacogenetic-Based Therapeutic Exploitation of Xanthine Dehydrogenase in Cardiovascular Disease
Massimo G, Dyson N, Olotu F, Khambata RS and Ahluwalia A
Antioxidants, Mdpi vol. 13 (12) 
22-11-2024
The NITRATE-OCT study-inorganic nitrate reduces in-stent restenosis in patients with stable coronary artery disease: a double-blind, randomised controlled trial
Rathod KS, Mathur A, Shabbir A, Khambata RS, Lau C, Beirne A-M, Chhetri I, Ono M, Belgaid DR, Massimo G, Ramasamy A, Tufaro V, Jain AK, Poulter N, Falaschetti E, Jones DA, Garcia-Garcia HM, Bourantas C, Learoyd A, Warren HR and Ahluwalia A
Eclinicalmedicine, Elsevier vol. 77 
18-10-2024
Introduction to the Theme “Novel Therapeutics with the Potential to Advance Health Care”
Insel PA, Amara SG and Ahluwalia A
The Annual Review of Pharmacology and Toxicology, Annual Reviews 
25-09-2024
Inorganic nitrate benefits contrast-induced nephropathy after coronary angiography for acute coronary syndromes: the NITRATE-CIN trial
Jones DA, Beirne A-M, Kelham M, Wynne L, Andiapen M, Rathod KS, Parakaw T, Adams J, Learoyd A, Khan K, Godec T, Wright P, Antoniou S, Wragg A, Yaqoob M, Mathur A and Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 45 (18), 1647-1658.  
21-03-2024
The effect of CTCA guided selective invasive graft assessment on coronary angiographic parameters and outcomes: Insights from the BYPASS-CTCA trial
Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Ramaseshan R, Learoyd AE, Forooghi N, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A, Jones DA and Investigators FTB-CT
Journal of Cardiovascular Computed Tomography, Elsevier vol. 18 (3), 291-296.  
11-03-2024

2023

Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke
Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A, Haffner C, Ahluwalia A, Seker BF and Plesnila N
Journal of Neuroinflammation, Springer Nature vol. 20 (1) 
15-12-2023
Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod K, Borghi C and Ahluwalia A
Redox Biology, Elsevier vol. 67 
21-10-2023
Computed Tomography Cardiac Angiography Before Invasive Coronary Angiography in Patients With Previous Bypass Surgery: The BYPASS-CTCA Trial
Jones DA, Beirne A-M, Kelham M, Rathod KS, Andiapen M, Wynne L, Godec T, Forooghi N, Ramaseshan R, Moon JC, Davies C, Bourantas CV, Baumbach A, Manisty C, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Committees and Investigators FTB-CT
Circulation, Wolters Kluwer vol. 148 (18), 1371-1380.  
29-09-2023
A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study
Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N, Kapil V, Godec T, Apea V, Flint J, Orkin C, Rathod KS and Ahluwalia A
Trials, Springer Nature vol. 24 (1) 
16-09-2023
Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod KS, Borghi C and Ahluwalia A
Redox Biology, Elsevier vol. 67 
04-09-2023
Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow
Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A and Raimondi C
Science Signaling, American Association For The Advancement of Science (Aaas) vol. 16 (786) 
23-05-2023
BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure
Panettieri RA, Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 180 (12), 1537-1541.  
24-04-2023
Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Panettieri RA, Patel HH, Sobey CG, Stefanska B, Stephens G, Teixeira M, Vergnolle N, Ferdinandy P and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 180 (9), 1191-1196.  
06-03-2023
Sodium nitrite poisoning: A series of 20 fatalities in which post-mortem blood nitrite and nitrate concentrations are reported
Hikin LJ, Ho J, Morley SR, Ahluwalia A and Smith PR
Forensic Science International, Elsevier vol. 345 
24-02-2023
Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC, Bansal J, Pitrola K, Shaw C, D'Acquisto F, Colas RA, Marelli-Berg F, Dalli J and Ahluwalia A
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 133 (2) 
17-01-2023

2022

Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis
Fernandes D, Khambata RS, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M, Barnes MR, Wade WG, Godec T, Orlandi M, D'Aiuto F and Ahluwalia A
Pharmacological Research, Elsevier vol. 188 
22-12-2022
Guidance for the use and reporting of anaesthetic agents in BJP manuscripts involving work with animals
Ingrande J, Patel HH, Kendall D, Stefanska B, Alexander S, Bakhle M, Cirino G, Docherty JR, George CH, Insel PA, Ji Y, King BF, Lilley E, Panettieri RA, Ramage AG, Sobey CG, Stanford SC, Stephens G, Teixeira M, Vergnolle N and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 180 (3), 255-263.  
18-12-2022
Sodium nitrite poisoning; A case series of 15 fatalities
Hikin L, Ahluwalia A, Morley S and Smith P
Toxicologie Analytique Et Clinique, Elsevier vol. 34 (3), s48-s49.  
01-09-2022
Planning experiments: Updated guidance on experimental design and analysis and their reporting III
Curtis MJ, Alexander SPH, Cirino G, George CH, Kendall DA, Insel PA, Izzo AA, Ji Y, Panettieri RA, Patel HH, Sobey CG, Stanford SC, Stanley P, Stefanska B, Stephens GJ, Teixeira MM, Vergnolle N and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 179 (15), 3907-3913.  
07-06-2022
Sex differences and sex bias in human circadian and sleep physiology research
Spitschan M, Santhi N, Ahluwalia A, Fischer D, Hunt L, Karp NA, Lévi F, Pineda-Torra I, Vidafar P and White R
Elife, Elife vol. 11 
18-02-2022
20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Moreira SAM, Rathod K, Chen J, Bubb K, Colas R, Khambata RS, Dalli J and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 179 (7), 1450-1469.  
14-02-2022

2021

The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction.
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S, Dalby MC, Malik IS, Whitbread M, Firoozi S, Bogle R, Redwood S, Cooper J, Gupta A, Lansky A, Wragg A, Mathur A and Ahluwalia A
Am J Cardiovasc Dis vol. 11 (5), 659-678.  
25-10-2021
Molecular imaging—The first visual themed issue published in the British Journal of Pharmacology
Maffia P, Antoniades C, Ahluwalia A and Cirino G
British Journal of Pharmacology, Wiley vol. 178 (21), 4213-4215.  
19-10-2021
Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V and Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 42 (Supplement_1) 
12-10-2021
Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation
Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A, Nuredini G, Godec T, Kapil V and Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 42 (Supplement_1) 
12-10-2021
A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate
Primus C, Masucci M, Whitear C, Moreira SAM, Kumar NA, Chhetri I, Rathod KS, Khambata R, Kapil V and Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 42 (Supplement_1) 
12-10-2021
Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide
Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP, Filomena F, Nuredini G, Ibrahim AS, Khambata RS, Gupta AK, Moon JC, Kapil V and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 179 (20), 4757-4777.  
06-10-2021
The BYPASS-CTCA Study: the value of Computed Tomography Cardiac Angiography (CTCA) in improving patient-related outcomes in patients with previous bypass operation undergoing invasive coronary angiography: Study Protocol of a Randomised Controlled Trial
Beirne A-M, Rathod KS, Castle E, Andiapen M, Richards A, Bellin A, Hammond V, Godec T, Moon JC, Davies C, Bourantas CV, Wragg A, Ahluwalia A, Pugliese F, Mathur A and Jones DA
Annals of Translational Medicine, Ame Publishing Company 
01-09-2021
Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications?
Wang J, Mei F, Bai L, Zhou S, Liu D, Yao L, Ahluwalia A, Ghiladi RA, Su L, Shu T, Gong M, Wang X, Zhu L, Cai K and Zhang X
Free Radical Biology and Medicine, Elsevier vol. 175, 216-225.  
30-08-2021
Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP)
George CH, Alexander SPH, Cirino G, Insel PA, Izzo AA, Ji Y, Kendall DA, Panettieri RA, Patel HH, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 178 (18), 3605-3610.  
30-07-2021
NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes
Beirne A-M, Mitchelmore O, Palma S, Andiapen M, Rathod KS, Hammond V, Bellin A, Cooper J, Wright P, Antoniou S, Yaqoob MM, Naci H, Mathur A, Ahluwalia A and Jones DA
Journal of Cardiovascular Pharmacology and Therapeutics, Sage Publications vol. 26 (4), 303-309.  
25-03-2021

2020

Therapeutic Implications of COVID-19 for the Interventional Cardiologist
Kelham M, Choudry FA, Hamshere S, Beirne A-M, Rathod KS, Baumbach A, Ahluwalia A, Mathur A and Jones DA
Journal of Cardiovascular Pharmacology and Therapeutics, Sage Publications vol. 26 (3), 203-216.  
17-12-2020
Second wave and second opportunity: capitalizing on cardiovascular research activity during the COVID-19 pandemic
Shabbir A and Ahluwalia A
European Heart Journal - Quality of Care and Clinical Outcomes, Oxford University Press (Oup) vol. 7 (3), 321-322.  
23-11-2020
Sex Differences in the Inflammatory Response: Pharmacological Opportunities for Therapeutics for Coronary Artery Disease
Shabbir A, Rathod KS, Khambata RS and Ahluwalia A
The Annual Review of Pharmacology and Toxicology, Annual Reviews vol. 61 (1), 1-27.  
09-10-2020
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H
Bmc Veterinary Research, Springer Nature vol. 16 (1) 
14-07-2020
ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stefanska B, Stephens G, Teixeira M and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 177 (16), 3611-3616.  
14-07-2020
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H
The Journal of Physiology, Wiley vol. 598 (18), 3793-3801.  
14-07-2020
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H
Plos Biology, Public Library of Science (Plos) vol. 18 (7) 
14-07-2020
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H
Cerebrovascular and Brain Metabolism Reviews, Sage Publications vol. 40 (9), 1769-1777.  
14-07-2020
The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway
Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM and Ahluwalia A
Pharmacological Reviews vol. 72 (3), 692-766.  
01-07-2020
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Wuerbel H
Bmj Open Science, Portico vol. 4 (1) 
01-07-2020
The many mechanisms of action of Chloroquine: to use or not to use (in COVID‐19) that is the question
Cirino G and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 177 (15), 3361-3362.  
30-06-2020
A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research
Izzo AA, Teixeira M, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Ji Y, Kendall DA, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 177 (10), 2169-2178.  
16-04-2020
Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: Protocol of the NITRATE-TOD study in the UK
Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A, Moon JC, Kapil V and Ahluwalia A
Bmj Open, Bmj Journals vol. 10 (1) 
21-01-2020

2019

Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia
Dreyer G, Kieswich J, Harwood S, Ahluwalia A and Yaqoob MM
Bioscience Reports, Portland Press vol. 39 (12) 
17-12-2019
The BJP expects authors to share data
George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 176 (24), 4595-4598.  
01-12-2019
The pharmacology of itch
Ingram JR and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 176 (23), 4419-4420.  
14-10-2019
The pharmacology of itch
Ingram JR and Ahluwalia A
British Journal of Dermatology, Wiley 
03-10-2019
Letter by Jones et al regarding article, “Optimized treatment of ST-elevation myocardial infarction”
Jones DA, Mathur A and Ahluwalia A
Circulation Research, American Heart Association vol. 125 (6), E29-E29.  
30-08-2019
Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable
Docherty JR, Stanford SC, Panettieri RA, Alexander SPH, Cirino G, George CH, Hoyer D, Izzo AA, Ji Y, Lilley E, Sobey CG, Stanley P, Stefanska B, Stephens G, Teixeira M and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 176 (21), 4081-4086.  
23-08-2019
Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H
, Cold Spring Harbor Laboratory 
15-07-2019
The ARRIVE guidelines 2019: updated guidelines for reporting animal research
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lidster K, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T and Würbel H
, Cold Spring Harbor Laboratory 
15-07-2019
Corrigendum to “The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction” [Int. J. Cardiol. 266 (2018) 1–6]
Jones DA, Rathod KS, Williamson A, Mand K, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A
International Journal of Cardiology, Elsevier vol. 292 
08-06-2019
Plan S: in Service or Disservice to Society?
Guzik TJ and Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 40 (12), 949-952.  
21-03-2019
Plan S: In service or disservice to society?
Guzik TJ and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 176 (6), 753-756.  
27-02-2019

2018

The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction
Jones DA, Rathod KS, Williamson A, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A
International Journal of Cardiology, Elsevier vol. 266, 1-6.  
01-09-2018
Clarification of the basis for the selection of requirements for publication in the British Journal of Pharmacology
Curtis MJ, Ashton JC, Moon LDF and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 175 (18), 3633-3635.  
24-08-2018
Sodium Nitrite-Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis.
AHLUWALIA A, JONES D and MATHUR A
Journal of Cardiovascular Pharmacology and Therapeutics, Sage Publications 
07-08-2018
P2564Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A and Ahluwalia A
European Heart Journal, Oxford University Press (Oup) vol. 39 (suppl_1) 
01-08-2018
Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, Watson DS, Barnes MR, Wade WG and Ahluwalia A
Free Radical Biology and Medicine, Elsevier vol. 126, 113-121.  
20-07-2018
Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis.
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C and Ahluwalia A
Faseb J, fj201701303-fj201701303.  
28-06-2018
Launch of mini‐reviews in hot topics
Ahluwalia A and Cirino G
British Journal of Pharmacology, Wiley vol. 175 (13), 2537-2537.  
15-06-2018
Revision of the ARRIVE guidelines: rationale and scope
du Sert NP, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Howells DW, Karp NA, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H and Holgate ST
Bmj Open Science, Portico vol. 2 (1) 
01-06-2018
The GTN patch: a simple and effective new approach to cardioprotection?
Yellon DM, He Z, Khambata R, Ahluwalia A and Davidson SM
Basic Research in Cardiology, Springer Nature vol. 113 (3) 
17-04-2018
Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Stanford SC, Teixeira MM, Wonnacott S and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 175 (7), 987-993.  
09-03-2018
Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology.
AHLUWALIA A
British Journal of Pharmacology, Wiley vol. 175, 407-411.  
19-01-2018

2017

Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting
Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A, Alam S, Brown M, Henderson H, de Leeuw W, Marsh J, Moher D, van Oort E, Rawle F, Riederer BM, Sanchez-Morgado J, Sena ES, Struthers C, Westmore M, Avey MT, Kalman R, O’Connor A, Sargeant J, Petrie A and Smith A
Bmc Veterinary Research, Springer Nature vol. 13 (1) 
07-11-2017
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017.
Kapil V
Bmc Pharmacol Toxicol vol. 18 (Suppl 1), 64-64.  
10-10-2017
NGF protects endothelial cells from indomethacin-induced injury through activation of mitochondria and upregulation of IGF-1
Ahluwalia A, Jones MK, Hoa N and Tarnawski AS
Cellular Signalling, Elsevier vol. 40, 22-29.  
24-08-2017
Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials.
Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A and Jones DA
Jrsm Cardiovasc Dis, Sage Journals vol. 6, 20480040177-20480040177.  
16-08-2017
Updating the guidelines for data transparency in the British Journal of Pharmacology – data sharing and the use of scatter plots instead of bar charts
George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Wonnacott S and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 174 (17), 2801-2804.  
11-08-2017
Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention
Campo G, Pavasini R, Morciano G, Lincoff MA, Gibson MC, Kitakaze M, Lonborg J, Ahluwalia A, Ishii H, Frenneaux M, Ovize M, Galvani M, Atar D, Ibanez B, Cerisano G, Biscaglia S, Neil BJ, Asakura M, Engstrom T, Jones DA, Dawson D, Ferrari R, Pinton P and Ottani F
Data in Brief, Elsevier vol. 14, 197-205.  
18-07-2017
Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1.
Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Cutillas PR, Ahluwalia A and Corder R
Sci Rep vol. 7 (1), 4956-4956.  
10-07-2017
Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials
Campo G, Pavasini R, Morciano G, Lincoff AM, Gibson CM, Kitakaze M, Lonborg J, Ahluwalia A, Ishii H, Frenneaux M, Ovize M, Galvani M, Atar D, Ibanez B, Cerisano G, Biscaglia S, Neil BJ, Asakura M, Engstrom T, Jones DA, Dawson D, Ferrari R, Pinton P and Ottani F
International Journal of Cardiology, Elsevier vol. 244, 59-66.  
13-06-2017
The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque
AHLUWALIA A
Proceedings of The National Academy of Sciences of Usa, National Academy of Sciences 
02-01-2017
Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation
Jones DA, Rathod KS and Ahluwalia A
In Nitric Oxide: Biology and Pathobiology: Third Edition 195-211.  
01-01-2017
Chapter 15 Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation
Jones DA, Rathod KS and Ahluwalia A
In Nitric Oxide, Elsevier 195-211.  
01-01-2017

2016

Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study
Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK, Deaner A, Poulter N, Caulfield MJ, Mathur A and Ahluwalia A
Bmj Open, Bmj vol. 6 (12) 
01-12-2016
Accelerated resolution underlies sex differences in the inflammatory response in human
AHLUWALIA A
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 127 (1), 169-182.  
28-11-2016
Nerve growth factor is critical requirement for in vitro angiogenesis in gastric endothelial cells
Ahluwalia A, Jones MK, Brzozowski T and Tarnawski AS
Ajp Gastrointestinal and Liver Physiology, American Physiological Society vol. 311 (5), g981-g987.  
13-10-2016
Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention.
Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A and Ahluwalia A
Heart, Bmj Publishing Group 
28-09-2016
Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy
Hoa NT, Ge L, Martini F, Chau V, Ahluwalia A, Kruse CA and Jadus MR
Expert Opinion On Therapeutic Targets, Taylor & Francis vol. 20 (10), 1155-1167.  
13-07-2016
Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim‐Shapiro DB, Lajous M, Larsen FJ, Lefer DJ, McClure LA, Nolan BT, Pluta R, Schechter A, Wang C, Ward MH and Harman JL
Journal of The American Heart Association, Wolters Kluwer vol. 5 (7) 
06-07-2016
In vivo imaging of porcine gastric enteric nervous system using confocal laser endomicroscopy &molecular neuronal probe
Samarasena JB, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ and Tarnawski AS
Journal of Gastroenterology and Hepatology, Wiley vol. 31 (4), 802-807.  
01-04-2016
Preliminary Findings on the Association Between Symptoms of Depression and Adherence to Antiretroviral Therapy in Individuals Born Inside Versus Outside of Canada
Ivanova E, Coroiu A, Ahluwalia A, Alexandrov E and Lafreniere KD
Journal of The Association of Nurses in Aids Care, Wolters Kluwer vol. 27 (4), 512-523.  
13-02-2016
Needs and Supports in Transitional Housing for People Living with HIV/AIDS in Ontario, Canada
Aguinaldo JP, Ahluwalia A, Hambly K, Koornstra J, Rankin B and Roesslein K
Journal of Social Service Research, Taylor & Francis vol. 42 (3), 352-362.  
05-02-2016
Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence
Gee LC and Ahluwalia A
Current Hypertension Reports, Springer Nature vol. 18 (2) 
27-01-2016
A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer?
Rathod KS, Velmurugan S and Ahluwalia A
Molecular Nutrition and Food Research vol. 60 (1), 185-202.  
01-01-2016

2015

Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study 1–3
Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V, Chowdhury TA, Curtis M, Kuhnle GG, Wade WG and Ahluwalia A
American Journal of Clinical Nutrition, Elsevier vol. 103 (1), 25-38.  
25-11-2015
Abstract 10110: Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis
Fernandes D, Khambata R and Ahluwalia A
Circulation, Wolters Kluwer vol. 132 (suppl_3) 
10-11-2015
Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation
Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM and Thorpe CM
Infection and Immunity, American Society For Microbiology vol. 84 (1), 138-148.  
19-10-2015
A ‘green’ diet‐based approach to cardiovascular health? Is inorganic nitrate the answer?
Rathod KS, Velmurugan S and Ahluwalia A
Molecular Nutrition & Food Research, Wiley vol. 60 (1), 185-202.  
13-09-2015
EUS-guided in vivo imaging of the porcine esophageal enteric nervous system by using needle-based confocal laser endomicroscopy
Samarasena JB, Tarnawski AS, Ahluwalia A, Shinoura S, Choi KD, Lee JG and Chang KJ
Gastrointestinal Endoscopy, Elsevier vol. 82 (6), 1116-1120.  
28-08-2015
Erratum

British Journal of Pharmacology, Wiley vol. 172 (18), 4600-4600.  
27-08-2015
Experimental design and analysis and their reporting: new guidance for publication in BJP
Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SPA, Giembycz MA, Gilchrist A, Hoyer D, Insel PA, Izzo AA, Lawrence AJ, MacEwan DJ, Moon LDF, Wonnacott S, Weston AH and McGrath JC
British Journal of Pharmacology, Wiley vol. 172 (14), 3461-3471.  
26-06-2015
Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532))
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A
Free Radical Biology and Medicine vol. 84 
29-05-2015
Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease
Tolstanova G, Deng X, Ahluwalia A, Paunovic B, Prysiazhniuk A, Ostapchenko L, Tarnawski A, Sandor Z and Szabo S
Digestive Diseases and Sciences, Springer Nature vol. 60 (10), 2963-2975.  
14-05-2015
Erratum to “Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex” [Free Radic. Biol. Med. 65 (2013) 1521–1532]
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A
Free Radical Biology and Medicine, Elsevier vol. 84 
02-05-2015
“Repurposing” of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension
Khambata RS, Ghosh SM and Ahluwalia A
Antioxidants & Redox Signaling, Mary Ann Liebert vol. 23 (4), 340-353.  
01-04-2015
Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis
Lara J, Ashor AW, Oggioni C, Ahluwalia A, Mathers JC and Siervo M
European Journal of Nutrition, Springer Nature vol. 55 (2), 451-459.  
13-03-2015
Confocal laser endomicroscopy: A new gold standard for the assessment of mucosal healing in ulcerative colitis
Macé V, Ahluwalia A, Coron E, Le Rhun M, Boureille A, Bossard C, Mosnier J, Matysiak‐Budnik T and Tarnawski AS
Journal of Gastroenterology and Hepatology, Wiley vol. 30 (S1), 85-92.  
01-03-2015
Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study
Kapil V, Khambata RS, Robertson A, Caulfield MJ and Ahluwalia A
Hypertension, Lippincott Williams and Wilkins vol. 65 (2), 320-327.  
21-02-2015
Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, Van Eijl S, Webb AJ, Westwood MA, Parmar MK, Mathur A and Ahluwalia A
Circulation Research vol. 116 (3), 437-447.  
01-01-2015

2014

Randomized Phase 2 Trial of Intracoronary Nitrite During Acute Myocardial Infarction
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, van Eijl S, Webb AJ, Westwood MA, Parmar MK, Mathur A and Ahluwalia A
Circulation Research, Wolters Kluwer vol. 116 (3), 437-447.  
15-12-2014
Angiogenesis in gastric mucosa: An important component of gastric erosion and ulcer healing and its impairment in aging
Tarnawski AS, Ahluwalia A and Jones MK
Journal of Gastroenterology and Hepatology, Wiley vol. 29 (S4), 112-123.  
01-12-2014
Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients
Kapil V, Khambata RS, Robertson A, Caulfield MJ and Ahluwalia A
Hypertension, Wolters Kluwer vol. 65 (2), 320-327.  
24-11-2014
P200 Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia
Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T and Ahluwalia A
Nitric Oxide, Elsevier vol. 42 
01-11-2014
P175 Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity
Rathod K, Ghosh S, Khambata R and Ahluwalia A
Nitric Oxide, Elsevier vol. 42 
01-11-2014
P141 The safety and efficacy of intra-coronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): A single centre, randomised, double-blind controlled trial
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood MA, Webb AJ, Mathur A and Ahluwalia A
Nitric Oxide, Elsevier vol. 42, 127-128.  
01-11-2014
Endothelial C-type natriuretic peptide maintains vascular homeostasis.
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock A-S, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A and Hobbs AJ
J Clin Invest vol. 124 (9), 4039-4051.  
01-09-2014
Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB
Ahluwalia A, Baatar D, Jones MK and Tarnawski AS
Ajp Gastrointestinal and Liver Physiology, American Physiological Society vol. 307 (6), g602-g610.  
24-07-2014
Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health.
Kapil V, Weitzberg E, Lundberg JO and Ahluwalia A
Nitric Oxide vol. 38, 45-57.  
30-04-2014
Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health
Kapil V, Weitzberg E, Lundberg JO and Ahluwalia A
Nitric Oxide - Biology and Chemistry vol. 38 (1), 45-57.  
30-04-2014
STAT3 and Importins Are Novel Mediators of Early Molecular and Cellular Responses in Experimental Duodenal Ulceration
Khomenko T, Deng X, Ahluwalia A, Tarnawski A, Patel KN, Sandor Z and Szabo S
Digestive Diseases and Sciences, Springer Nature vol. 59 (2), 297-306.  
03-01-2014
Increased susceptibility of aging gastric mucosa to injury: The mechanisms and clinical implications
Tarnawski AS, Ahluwalia A and Jones MK
World Journal of Gastroenterology, Baishideng Publishing Group vol. 20 (16), 4467-4482.  
01-01-2014
VEGF and colon cancer growth beyond angiogenesis: does VEGF directly mediate colon cancer growth via a non-angiogenic mechanism?
Ahluwalia A, Jones MK, Matysiak-Budnik T and Tarnawski AS
Current Pharmaceutical Design, Bentham Science Publishers vol. 20 (7), 1041-1044.  
01-01-2014

2013

Key role of endothelial importin-α in VEGF expression and gastric angiogenesis: novel insight into aging gastropathy
Ahluwalia A, Jones MK and Tarnawski AS
Ajp Gastrointestinal and Liver Physiology, American Physiological Society vol. 306 (4), g338-g345.  
19-12-2013
Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex.
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A
Free Radic Biol Med vol. 65, 1521-1532.  
01-12-2013
Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene
Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAI, Jegard J, Montoya A, Cutillas P, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Ahluwalia A and Corder R
Life Sciences, Elsevier vol. 93 (25-26) 
01-12-2013
Activation of neuronal transient receptor potential vanilloid 1 channel underlies 20-hydroxyeicosatetraenoic acid-induced vasoactivity: role for protein kinase A.
Bubb KJ, Wen H, Panayiotou CM, Finsterbusch M, Khan FJ, Chan MV, Priestley JV, Baker MD and Ahluwalia A
Hypertension vol. 62 (2), 426-433.  
01-08-2013
Aberrant, ectopic expression of VEGF and VEGF receptors 1 and 2 in malignant colonic epithelial cells. Implications for these cells growth via an autocrine mechanism
Ahluwalia A, Jones MK, Szabo S and Tarnawski AS
Biochemical and Biophysical Research Communications, Elsevier vol. 437 (4), 515-520.  
04-07-2013
An imbalance between VEGF and endostatin underlies impaired angiogenesis in gastric mucosa of aging rats
Ahluwalia A, Jones MK, Deng X, Sandor Z, Szabo S and Tarnawski AS
Ajp Gastrointestinal and Liver Physiology, American Physiological Society vol. 305 (4), g325-g332.  
20-06-2013
Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential.
Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S, Yousuf M, Benjamin N, Webb AJ, Caulfield MJ, Hobbs AJ and Ahluwalia A
Hypertension vol. 61 (5), 1091-1102.  
01-05-2013
Physiological role for nitrate-reducing oral bacteria in blood pressure control.
Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E and Ahluwalia A
Free Radic Biol Med vol. 55, 93-100.  
01-02-2013
Letter by Ahluwalia and Hobbs Regarding Article, Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics
Ahluwalia A and Hobbs AJ
Circulation vol. 127 (2), E275-E275.  
01-01-2013
The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial.
Jones DA, Andiapen M, Van-Eijl TJA, Webb AJ, Antoniou S, Schilling RJ, Ahluwalia A and Mathur A
Bmj Open vol. 3 (4) 
01-01-2013
CXCL5 limits macrophage foam cell formation in atherosclerosis
Rousselle A, Qadri F, Leukel L, Yilmaz R, Fontaine J-F, Sihn G, Bader M, Ahluwalia A and Duchene J
Journal of Clinical Investigation vol. 123 (3), 1343-1347.  
01-01-2013
Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ, Poole A and Ahluwalia A
Free Radical Biology and Medicine vol. 65, 1521-1532.  
01-01-2013

2012

Abstract 18898: Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P, Hartley O, Ahluwalia A and Corder R
Circulation, Wolters Kluwer vol. 126 (suppl_21) 
20-11-2012
Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.
Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS and Ahluwalia A
Br J Pharmacol vol. 167 (4), 805-817.  
01-10-2012
Sexual dimorphism in rodent models of hypertension and atherosclerosis.
Bubb KJ, Khambata RS and Ahluwalia A
Br J Pharmacol vol. 167 (2), 298-312.  
01-09-2012
Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase.
Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A and Hobbs AJ
Circulation vol. 125 (23), 2922-2932.  
12-06-2012
Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers.
Bahra M, Kapil V, Pearl V, Ghosh S and Ahluwalia A
Nitric Oxide vol. 26 (4), 197-202.  
15-05-2012
20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel.
Wen H, Östman J, Bubb KJ, Panayiotou C, Priestley JV, Baker MD and Ahluwalia A
J Biol Chem vol. 287 (17), 13868-13876.  
20-04-2012
Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves.
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD, Perretti M, Ahluwalia A, Priestley JV, Chavakis T, Imhof BA, Feltri ML and Nourshargh S
Faseb J vol. 26 (3), 1064-1076.  
01-03-2012
Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P, Hartley O, Ahluwalia A and Corder R
Circulation vol. 126 (21) 
01-01-2012
Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP
Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V and Ahluwalia A
Circulation vol. 126 (21) 
01-01-2012
Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide
Moyes AJ, Khambata RS, Ahluwalia A and Hobbs AJ
Circulation vol. 126 (21) 
01-01-2012
Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib
Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV, Magun BE and Jandhyala DM
Frontiers in Cellular and Infection Microbiology, Frontiers vol. 2 
01-01-2012

2011

Kallikrein-kinin system in inflammation
Duchene J and Ahluwalia A
, 261-272.  
30-11-2011
16 Kallikrein-kinin system in infl ammation
Duchene J and Ahluwalia A
In Kinins, De Gruyter 261-272.  
16-11-2011
Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
Paunovic B, Deng X, Khomenko T, Ahluwalia A, Tolstanova G, Tarnawski A, Szabo S and Sandor Z
Journal of Pharmacology and Experimental Therapeutics, Elsevier vol. 339 (2), 430-437.  
12-08-2011
Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons
Florkiewicz RZ, Ahluwalia A, Sandor Z, Szabo S and Tarnawski AS
Biochemical and Biophysical Research Communications, Elsevier vol. 409 (3), 494-499.  
11-05-2011
Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin.
Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ and Ahluwalia A
Arterioscler Thromb Vasc Biol vol. 31 (5), 1075-1083.  
01-05-2011
Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/AIDS in Ontario: Results From the Positive Spaces, Healthy Places Study
Monette LE, Rourke SB, Gibson K, Bekele TM, Tucker R, Greene S, Sobota M, Koornstra J, Byers S, Marks E, Bacon J, Watson JR, Hwang SW, Ahluwalia A, Dunn JR, Guenter D, Hambly K, Bhuiyan S and Positive Spaces Healthy Places Team
Canadian Journal of Public Health, Springer Nature vol. 102 (3), 215-219.  
01-05-2011
Response to Inorganic Nitrate for Blood Pressure Lowering?
Kapil V, Benjamin N, Hobbs A and Ahluwalia A
Hypertension vol. 57 (2), E3-E3.  
01-02-2011
Social determinants of health associated with hepatitis C co-infection among people living with HIV: results from the Positive Spaces, Healthy Places study.
Rourke SB, Sobota M, Tucker R, Bekele T, Gibson K, Greene S, Price C, Koornstra JJJ, Monette L, Byers S, Watson J, Hwang SW, Guenter D, Dunn J, Ahluwalia A, Wilson MG and Bacon J
Open Medicine vol. 5 (3), e120-e131.  
01-01-2011

2010

Inorganic nitrate and the cardiovascular system.
Kapil V, Webb AJ and Ahluwalia A
Heart vol. 96 (21), 1703-1709.  
01-11-2010
Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice.
Yamashiro K, Milsom AB, Duchene J, Panayiotou C, Urabe T, Hattori N and Ahluwalia A
J Cereb Blood Flow Metab vol. 30 (8), 1494-1503.  
01-08-2010
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N, Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ and Ahluwalia A
Hypertension vol. 56 (2), 274-281.  
01-08-2010
PTEN silencing reverses aging-related impairment of angiogenesis in microvascular endothelial cells
Tarnawski AS, Pai R, Tanigawa T, Matysiak-Budnik T and Ahluwalia A
Biochemical and Biophysical Research Communications, Elsevier vol. 394 (2), 291-296.  
01-03-2010
Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice
Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ, Cuzzocrea S, Hobbs AJ, Thiemermann C and Ahluwalia A
Nitric Oxide-Biol Ch vol. 22 (2), 141-148.  
15-02-2010
A Role of Matrix Metalloproteinase-8 in Atherosclerosis: Correction

Circulation Research, Wolters Kluwer vol. 106 (1) 
08-01-2010
Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System
WEBB A, Webb A and Ahluwalia A
In Nitric Oxide Biology and Pathobiology, Academic Press, Editors: Ignarro LJ. 555-586.  
01-01-2010
Chapter 17 Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System
Webb A and Ahluwalia A
In Nitric Oxide, Elsevier 555-586.  
01-01-2010
Mechanisms of nitrite reduction in ischemia in the cardiovascular system
Webb AJ and Ahluwalia A
In Nitric Oxide: Biology and Pathobiology, Elsevier, Editors: Ignarro L. 555-586.  
01-01-2010

2009

Nitrate and nitrite in biology, nutrition and therapeutics
Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, Kim-Shapiro DB, Kozlov AV, Lancaster JR, Lefer DJ, McColl K, McCurry K, Patel RP, Petersson J, Rassaf T, Reutov VP, Richter-Addo GB, Schechter A, Shiva S, Tsuchiya K and van Faassen EE
Nat Chem Biol vol. 5 (12), 865-869.  
01-12-2009
Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis.
Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P, Marrelli A, Pitzalis C, Cipollone F, Schanstra J, Bascands J-L, Hobbs AJ, Perretti M and Ahluwalia A
Arterioscler Thromb Vasc Biol vol. 29 (11), 1757-1763.  
01-11-2009
A role of matrix metalloproteinase-8 in atherosclerosis.
Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung K-Y, Xiao Q, Scotland RS, Hodgkinson CP, Smith K, Willeit J, López-Otín C, Simpson IA, Kiechl S, Ahluwalia A, Xu Q and Ye S
Circ Res vol. 105 (9), 921-929.  
23-10-2009
Between skepticism and empowerment: the experiences of peer research assistants in HIV/AIDS, housing and homelessness community‐based research
Greene S, Ahluwalia A, Watson J, Tucker R, Rourke SB, Koornstra J, Sobota M, Monette L and Byers S
International Journal of Social Research Methodology, Taylor & Francis vol. 12 (4), 361-373.  
01-10-2009
“Under My Umbrella”: The housing experiences of HIV positive parents who live with and care for their children in Ontario
Greene S, Tucker R, Rourke SB, Monette L, Koornstra J, Sobota M, Byers S, Hwang S, Dunn J, Guenter D, Ahluwalia A and Watson J
Archives of Women's Mental Health, Springer Nature vol. 13 (3), 223-232.  
16-09-2009
BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE
Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A and Ahluwalia A
Basic Clin Pharmacol vol. 105, 31-31.  
01-08-2009
ORAL INORGANIC NITRATE PROTECTS AGAINST ENDOTHELIAL ISCHAEMIA-REPERFUSION INJURY IN HUMANS
Okorie M, Akram F, Loukogeorgakis S, Webb A, Deanfield J, Benjamin N, Hobbs A, MacAllister R and Ahluwalia A
Basic Clin Pharmacol vol. 105, 26-26.  
01-08-2009
The kinin B(1) receptor and inflammation: new therapeutic target for cardiovascular disease.
Duchene J and Ahluwalia A
Curr Opin Pharmacol vol. 9 (2), 125-131.  
01-04-2009
Design and development of novel non-peptide agonists at natriuretic peptide receptor-C
Hobbs AJ, Gane P, Lumsden N, Nobles M, Rebstock A-S, Simone M, Villar I, Worthington R, Xiao F, Ahluwalia A and Selwood D
Faseb Journal vol. 23 
01-01-2009
Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy
Klein J, Gonzalez J, Duchene J, Esposito L, Pradere JP, Neau E, Delage C, Calise D, Ahluwalia A, Carayon P, Pesquero JB, Bader M, Schanstra JP and Bascands JL
Faseb J vol. 23 (1), 134-142.  
01-01-2009

2008

Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF
Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, Szabo S and Sandor Z
Journal of Pharmacology and Experimental Therapeutics, Elsevier vol. 328 (3), 749-757.  
05-12-2008
Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia: role for xanthine oxidoreductase and endothelial nitric oxide synthase.
Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FMJ, Perrett D, Raimondo C, Khoshbin E, Ahmed Z, Uppal R, Benjamin N, Hobbs AJ and Ahluwalia A
Circ Res vol. 103 (9), 957-964.  
24-10-2008
Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor
Villar IC, Hobbs AJ and Ahluwalia A
J Endocrinol vol. 197 (3), 447-462.  
01-06-2008
ZAK: a MAP3Kinase that transduces Shiga toxin‐ and ricin‐induced proinflammatory cytokine expression
Jandhyala DM, Ahluwalia A, Obrig T and Thorpe CM
Cellular Microbiology, Hindawi vol. 10 (7), 1468-1477.  
10-03-2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A
Hypertension vol. 51 (3), 784-790.  
01-03-2008
Acute blood pressure lowering and vasoprotective effects of dietary nitrate
Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin B, Macallister R, Hobbs A and Abluwalia A
Faseb Journal vol. 22 
01-01-2008
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite.
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ and Ahluwalia A
Hypertension, American Heart Association vol. 51, 784-790.  
01-01-2008

2007

A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5.
Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M and Ahluwalia A
J Immunol vol. 179 (7), 4849-4856.  
01-10-2007
12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1.
Sexton A, McDonald M, Cayla C, Thiemermann C and Ahluwalia A
Faseb J vol. 21 (11), 2695-2703.  
01-09-2007
Aging Gastropathy—Novel Mechanisms: Hypoxia, Up-regulation of Multifunctional Phosphatase PTEN, and Proapoptotic Factors
Tarnawski A, Pai R, Deng X, Ahluwalia A, Khomenko T, Tanigawa T, Akahoshi T, Sandor Z and Szabo S
Gastroenterology, Elsevier vol. 133 (6), 1938-1947.e1.  
21-08-2007
Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor
Villar IC, Panayiotou CM, Sheraz A, Madhani M, Scotland RS, Nobles M, Kemp-Harper B, Ahluwalia A and Hobbs AJ
Cardiovasc Res vol. 74 (3), 515-525.  
01-06-2007
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase.
Tripatara P, Patel NSA, Webb A, Rathod K, Lecomte FMJ, Mazzon E, Cuzzocrea S, Yaqoob MM, Ahluwalia A and Thiemermann C
J Am Soc Nephrol vol. 18 (2), 570-580.  
01-02-2007

2006

Distinct pathways regulate endothelium derived hyperpolarising factor-mediated responses in rat mesenteric arteries
Villar IC, Ahluwalia A and Hobbs AJ
Acta Pharmacol Sin vol. 27 (9), 1276-1276.  
01-09-2006
Novel aspects of endothelium-dependent regulation of vascular tone
Villar IC, Francis S, Webb A, Hobbs AJ and Ahluwalia A
Kidney Int vol. 70 (5), 840-853.  
01-09-2006

2005

C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression
Scotland RS, Cohen M, Foster P, Lovell M, Mathur A, Ahluwalia A and Hobbs AJ
P Natl Acad Sci Usa vol. 102 (40), 14452-14457.  
04-10-2005
Xanthine oxidase activity provides an alternative source of no during ischaemia from inorganic nitrite in rat blood vessels
Webb A, Qureshi S, Benjamin N, Perrett D and Ahluwalia A
Brit J Clin Pharmaco vol. 59 (5), 631-632.  
01-05-2005
Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor
Ahluwalia A and Hobbs AJ
Trends Pharmacol Sci vol. 26 (3), 162-167.  
01-03-2005
autoregulatory role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function.
Vo PA, Lad B, Tomlinson JAP, Francis S and Ahluwalia A
J Biol Chem vol. 280 (8), 7236-7243.  
25-02-2005
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice - Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo
Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, Hobbs AJ and Ahluwalia A
Circulation vol. 111 (6), 796-803.  
15-02-2005
C-type natniuretic peptide in vascular physiology and disease
Scotland RS, Ahluwalia A and Hobbs AJ
Pharmacol Therapeut vol. 105 (2), 85-93.  
01-02-2005
Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo
Ahluwalia A, SCOTLAND RS, Andersen J, Chauhan S, Moncada S, Nilsson H, Hobbs AJ and Madhani M
Circulation vol. 111 (6), 796-803.  
01-02-2005
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo.
AHLUWALIA A, Scotland RS, Hobbs AJ, Moncada S, Chauhan S, Andresen J, Nilsson H and Madhani M
Circulation vol. 111 (6), 796-803.  
01-01-2005
role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function.
AHLUWALIA A, Francis S, Tomlinson JA, Lad B and Vo PA
J Biol Chem vol. 25280 (8), 7236-7243.  
01-01-2005
C-type natriuretic peptide inhibits leukocyte recruitment and platelet aggregation
AHLUWALIA A, Mathur A, Lovell M, Hobbs AJ, Cohen M and Scotland RS
Pnas vol. 102 (40), 14452-14457.  
01-01-2005

2004

Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction.
Scotland RS, Chauhan S, Davis C, De Felipe C, Hunt S, Kabir J, Kotsonis P, Oh U and Ahluwalia A
Circ Res vol. 95 (10), 1027-1034.  
12-11-2004
Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction
AHLUWALIA A, Oh U, Kabir J, De Felipe C, Chauhan S, Scotland RS, Davis C, Hunt S and Kotsonis P
Circ Res vol. 95 (10), 1027-1034.  
01-11-2004
C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor.
Chauhan SD, Hobbs AJ and Ahluwalia A
Int J Biochem Cell Biol vol. 36 (10), 1878-1881.  
01-10-2004
Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage
Webb A, Bond R, McLean P, Uppal R, Benjamin N and Ahluwalia A
P Natl Acad Sci Usa vol. 101 (37), 13683-13688.  
14-09-2004
Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury - Novel cardioprotective role for endothelium-derived C-type natriuretic peptide
Hobbs A, Foster P, Prescott C, Scotland R and Ahluwalia A
Circulation vol. 110 (10), 1231-1235.  
01-09-2004
Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms.
Ahluwalia A, MacAllister RJ and Hobbs AJ
Basic Res Cardiol vol. 99 (2), 83-89.  
01-03-2004
DICHOTOMOUS ROLE OF THE ENDOTHELIUM IN LPS-INDUCED ENDOTHELIAL DYSFUNCTION
AHLUWALIA A
Shock, Wolters Kluwer vol. 21 (Supplement) 
01-03-2004
Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment
Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S and Hobbs AJ
P Natl Acad Sci Usa vol. 101 (5), 1386-1391.  
03-02-2004
Protease-activated receptor (PAR)-2 causes endothelium-dependant, NO-independant coronary vasodilatation: involvement of C-fibres and EDHF.
AHLUWALIA A, Sarkar D, Aston D and McLean P
Circ. Res vol. 90, 465-472.  
01-01-2004
Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide.
AHLUWALIA A, Hobbs A, Prescott C, Scotland R and Foster P
Circulation vol. 110 (10), 1231-1235.  
01-01-2004
Inhibition of leukocyte-endothelial cell interactions by nitric oxide via a cGMP-mediated down-regulation of P-selectin expression.
Ahluwalia A, PERRETTI M, Mathur A, Moncada S, McLean PG, Hobbs AJ, Scotland RS and Foster P
Proceedings of The National Academy of Sciences Usa vol. 101, 1386-1391.  
01-01-2004

2003

To b'EET or not to b'EET? That is the question!
Ahluwalia A
Clin Sci (Lond) vol. 105 (4), 399-401.  
01-10-2003
Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor
Chauhan SD, Nilsson H, Ahluwalia A and Hobbs AJ
P Natl Acad Sci Usa vol. 100 (3), 1426-1431.  
04-02-2003
Protection against liposaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice.
AHLUWALIA A, Hobbs AJ, Seggara G, Chauhan SD, Vo PA and MacAllister RJ
Faseb J vol. 17 (6), 773-775.  
01-01-2003
NO contributes to EDHF-like responses in rat small arteries: a role for NO stores.
Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R and Ahluwalia A
Cardiovasc Res vol. 57 (1), 207-216.  
01-01-2003

2002

Mechanisms underlying the vasorelaxant activity of C-type natriuretic peptide (CNP) in rat mesenteric resistance arteries
Chauhan SD, MacAllister RJ, Hobbs AJ and Ahluwalia A
Faseb J vol. 16 (4), A572-A572.  
20-03-2002
Protease-activated receptor (PAR)-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia-reperfusion injury, involvement of lipoxygenase products, VR1 receptors and C-fibers
McLean P and Ahluwalia A
Faseb J vol. 16 (4), A569-A569.  
20-03-2002
Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation - Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors, and C-fibers
McLean PG, Aston D, Sarkar D and Ahluwalia A
Circ Res vol. 90 (4), 465-472.  
08-03-2002
Regulation of GTP Cyclohydrolase I by Estrogen
Hesslinger C, Chen Z, Ahluwalia A, Selwood DL, Vallance P, Pfeilschifter J and Hingorani AD
In Chemistry and Biology of Pteridines and Folates, Springer Nature 157-161.  
01-01-2002

2001

An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide.
Scotland RS, Chauhan S, Vallance PJ and Ahluwalia A
Hypertension vol. 38 (4), 833-839.  
01-10-2001
Nepadutant Menarini Richerche.
Ahluwalia A
Curr Opin Investig Drugs vol. 2 (7), 919-922.  
01-07-2001
An EDHF-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of eNOS-derived nitric oxide
Ahluwalia A, SCOTLAND RS, Vallance PJ and Chauhan S
Hypertension vol. 38 (4), 833-839.  
01-01-2001

2000

Kinin B1 receptors and the cardiovascular system: regulation of expression and function
McLean PG, Perretti M and Ahluwalia A
Cardiovascular Research, Oxford University Press (Oup) vol. 48 (2), 194-210.  
01-11-2000
Association between Kinin B1 Receptor Expression and Leukocyte Trafficking across Mouse Mesenteric Postcapillary Venules
McLean PG, Ahluwalia A and Perretti M
Journal of Experimental Medicine, Rockefeller University Press vol. 192 (3), 367-380.  
31-07-2000
Endogenous factors involved in regulation of tone of arterial vasa vasorum: implications for conduit vessel physiology
Scotland RS, Vallance PJT and Ahluwalia A
Cardiovascular Research, Oxford University Press (Oup) vol. 46 (3), 403-411.  
01-06-2000
The Microcirculation and Inflammation: Site of Action for Glucocorticoids
PERRETTI M and AHLUWALIA A
Microcirculation, Wiley vol. 7 (3), 147-161.  
01-06-2000
Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia
Bogle RG, McLean PG, Ahluwalia A and Vallance P
British Journal of Pharmacology, Wiley vol. 130 (1), 118-124.  
01-05-2000
Kinin B1 receptors as novel anti-inflammatory targets
McLean PG, Perretti M and Ahluwalia A
Expert Opinion On Therapeutic Targets, Taylor & Francis vol. 4 (2), 127-141.  
01-04-2000
Evidence that no may contribute to EDHF-like responses in rat mesenteric and hepatic small arteries
Chauhan SD, MacAllister RJ, Clapp LH and Ahluwalia A
British Journal of Pharmacology vol. 129 
01-01-2000
Activation of sensory C-fibres partially mediates the vascular myogenic response
Ahluwalia A and Scotland R
Faseb Journal vol. 14 (4), A143-A143.  
01-01-2000

1999

Cholinergic Contraction Is Altered in nNOS Knockouts
KAKUYAMA M, AHLUWALIA A, RODRIGO J and VALLANCE P
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society vol. 160 (6), 2072-2078.  
01-12-1999
Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology
Scotland R, Vallance P and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 128 (6), 1229-1234.  
01-11-1999
Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des‐Arg9bradykinin‐induced coronary vasodilation
McLean PG, Perretti M and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 128 (2), 275-282.  
01-09-1999
B1 receptors as a new inflammatory target. Could this B the 1?
Ahluwalia A and Perretti M
Trends in Pharmacological Sciences, Elsevier vol. 20 (3), 100-104.  
01-03-1999
On the regulation of tone in vasa vasorum
Scotland R, Vallance P and Ahluwalia A
Cardiovascular Research, Oxford University Press (Oup) vol. 41 (1), 237-245.  
01-01-1999
The involvement of kinin B1 receptors in the hypotensive response to endotoxin in rats
McLean PG, Perretti M and Ahluwalia A
British Journal of Pharmacology vol. 127, U62-U62.  
01-01-1999
Investigation of the α1 adrenoceptor subtype(s) mediating contraction in the human internal mammary artery
Varsani M, MacAllister R, Ahluwalia A and Marshall I
British Journal of Pharmacology vol. 127 
01-01-1999

1998

Impaired IL‐1β‐induced neutrophil accumulation in tachykinin NK1 receptor knockout mice
Ahluwalia A, De Felipe C, O'Brien J, Hunt SP and Perretti M
British Journal of Pharmacology, Wiley vol. 124 (6), 1013-1015.  
01-07-1998
Ovalbumin‐induced neurogenic inflammation in the bladder of sensitized rats
Ahluwalia A, Giuliani S, Scotland R and Maggi CA
British Journal of Pharmacology, Wiley vol. 124 (1), 190-196.  
01-05-1998
Topical glucocorticoids and the skin‐mechanisms of action: an update
Ahluwalia A
Mediators of Inflammation, Wiley vol. 7 (3), 183-193.  
01-01-1998
Endothelium‐dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store
Kakuyama M, Vallance P and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 123 (2), 310-316.  
01-01-1998
Investigation of endotoxin-inducible B1 and constitutive B2 kinin receptors mediating coronary vasodilation in the rat isolated heart.
McLean PG, Perretti M and Ahluwalia A
Naunyn-Schmiedebergs Archives of Pharmacology vol. 358 (1), R335-R335.  
01-01-1998

1997

Modification of Delivery System Enhances MHC Nonrestricted Immunogenicity of V3 Loop Region of HIV‐1 gp120
Ahluwalia A, Gokulan K, Nath I and Rao DN
Microbiology and Immunology, Wiley vol. 41 (10), 779-784.  
01-10-1997
Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins.
Ahluwalia A and Vallance P
Journal of Pharmacology and Experimental Therapeutics vol. 281 (1), 9-14.  
01-04-1997
Allergic inflammation in the rat urinary bladder: Involvement of mast cells and C-fibres
Ahluwalia A, Giuliani S and Maggi CA
British Journal of Pharmacology vol. 122 
01-01-1997
Regulation of the cardiovascular system by non-adrenergic non-chollnergic nerves
Ahluwalia A and Cellek S
Current Opinion in Nephrology & Hypertension, Wolters Kluwer vol. 6 (1), 74-79.  
01-01-1997
Comparison of vascular reactivity of porcine aorta and its vasa vasorum
Scotland RS, Vallance PJ and Ahluwalia A
Circulation vol. 96 (8), 908-908.  
01-01-1997
P-30 Non-adrenergic non-cholinergic relaxation of the rabbit mesenteric small artery: Involvement of NO
Kakuyama M, Vallance PJ and Ahluwalia A
Journal of Pharmacological Sciences, Elsevier vol. 75 
01-01-1997

1996

Investigation of notalgia paraesthetica using laser Doppler velocimetry and immunohistochemistry before and after treatment with topical capsaicin
Halpern SM, Ahluwalia A, Makunura CN and Jordan S
Journal of The European Academy of Dermatology and Venereology, Wiley vol. 7 (3), 228-234.  
01-11-1996
Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide
Ahluwalia A and Vallance P
American Journal of Physiology, American Physiological Society vol. 271 (3), h969-h976.  
01-09-1996
Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1
Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK and Flower RJ
British Journal of Pharmacology, Wiley vol. 117 (6), 1145-1154.  
01-03-1996
Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse.
Ahluwalia A and Perretti M
The Journal of Immunology, The American Association of Immunologists vol. 156 (1), 269-274.  
01-01-1996
Reactivity of the vasa vasorum
Ahluwalia A and Vallance PJ
Circulation vol. 94 (8), 3443-3443.  
01-01-1996

1995

Demonstration of a ‘septide‐sensitive’ inflammatory response in rat skin
Ahluwalia A, Giuliani S and Maggi CA
British Journal of Pharmacology, Wiley vol. 116 (4), 2170-2174.  
01-10-1995
Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1
Ahluwalia A, Newbold P, Brain SD and Flower RJ
European Journal of Pharmacology, Elsevier vol. 283 (1-3), 193-198.  
01-09-1995
TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1
AHLUWALIA A, NEWBOLD P and FLOWER RJ
British Journal of Pharmacology vol. 114, P61-P61.  
01-01-1995
DEMONSTRATION OF A SEPTIDE-SENSITIVE INFLAMMATORY RESPONSE IN RAT SKIN
AHLUWALIA A, GIULIANI S and MAGGI CA
British Journal of Pharmacology vol. 114, P41-P41.  
01-01-1995

1994

Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse
Ahluwalia A and Perretti M
European Journal of Pharmacology, Elsevier vol. 264 (3), 407-415.  
01-11-1994
Induction of lipocortin 1 by topical steroid in rat skin
Ahluwalia A, Mohamed RW and Flower RJ
Biochemical Pharmacology, Elsevier vol. 48 (8), 1647-1654.  
01-10-1994
Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder
Ahluwalia A, Maggi CA, Santicioli P, Lecci A and Giuliani S
British Journal of Pharmacology, Wiley vol. 111 (4), 1017-1022.  
01-04-1994
Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors.
Ahluwalia A and Perretti M
Journal of Pharmacology and Experimental Therapeutics vol. 268 (3), 1526-1531.  
01-03-1994
CHARACTERIZATION OF CAPSAICIN-INDUCED VASODILATION OF THE PERFUSED RABBIT EAR AND ITS MODULATION BY DEXAMETHASONE
AHLUWALIA A and FLOWER RJ
British Journal of Pharmacology vol. 112, U104-U104.  
01-01-1994

1993

Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.
Perretti M, Ahluwalia A, Harris JG, Goulding NJ and Flower RJ
The Journal of Immunology, The American Association of Immunologists vol. 151 (8), 4306-4314.  
15-10-1993
Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors.
Perretti M, Ahluwalia A, Flower RJ and Manzini S
Immunology vol. 80 (1), 73-77.  
01-09-1993
Investigations into the mechanism of vasoconstrictor action of the topical steroid betamethasone‐17‐valerate in the rat
Ahluwalia A and Flower RJ
British Journal of Pharmacology, Wiley vol. 108 (2), 544-548.  
01-02-1993
DUAL-ACTION OF PROSTAGLANDINS (PGS) IN THE MOUSE SKIN EDEMA TEST
AHLUWALIA A, FLOWER RJ and PERRETTI M
British Journal of Pharmacology vol. 109, P5-P5.  
01-01-1993
Topical betamethasone‐17‐valerate inhibits heat‐induced vasodilatation in man
AHLUWALIA A and FLOWER RJ
British Journal of Dermatology, Oxford University Press (Oup) vol. 128 (1), 45-48.  
01-01-1993

1992

Steroid inhibition of oedema formation in the rat skin
Ahluwalia A, Peers SH and Flower RJ
British Journal of Pharmacology, Wiley vol. 106 (3), 628-631.  
01-07-1992
TOPICAL STEROIDS AND ACE INHIBITORS - A COMMON LINK
AHLUWALIA A and FLOWER RJ
British Journal of Pharmacology vol. 106, P5-P5.  
01-01-1992

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconContinuum-Lint QM Abbott funding
Anthony Mathur and Amrita Ahluwalia
£174,960
01-12-2024 - 30-09-2025
bullet iconFeasibility study to determine the potential for a food fortification platform to provide population scale mitigation of heart disease risk
Amrita Ahluwalia and Anthony Mathur
£120,848 Innovate UK
01-10-2024 - 31-12-2025
bullet iconQMUL 4th Intake 2024, 4 Year PhD Studentship (5th) Scheme
Amrita Ahluwalia
£479,408 BHF British Heart Foundation
01-10-2024 - 30-09-2028
bullet iconEnhancing Cardiovascular cGMP to Target Hypertensive Heart Failure in Females
Amrita Ahluwalia
£139,727 NHMRC National Health and Medical Research Council (Australia)
02-04-2024 - 01-04-2027
bullet iconQMUL 3rd intake, 2023 4-Year PhD Studentship (5th) Scheme
Amrita Ahluwalia
£479,924 BHF British Heart Foundation
01-10-2023 - 30-09-2027
bullet iconA randomised trial assessing the duration of anti-coagulation treatment for LV thrombus QMUL Part
Daniel Jones and Amrita Ahluwalia
£277,790 Barts and the London Charity
01-03-2023 - 28-02-2026
bullet iconQMUL 2nd intake 2022 - 4 Year PhD Studentship (5th) Scheme
Amrita Ahluwalia
£447,561 BHF British Heart Foundation
01-10-2022 - 30-09-2026
bullet iconRandomised Control Trial: Cryoballoon/Radio frequency ablation of a trial fibrillation versus medical treatment for heart failureTreatment
Amrita Ahluwalia
£975,493 BHF British Heart Foundation
01-09-2022 - 28-02-2028
bullet iconClinical Investigation of the Tricento Tricuspid Valve for TR in Patients with Carcinoid HD
Andreas Baumbach, Anthony Mathur, Ruth Bowles and Amrita Ahluwalia
£369,055 Barts and the London Charity
01-08-2022 - 31-07-2025
bullet iconAssessment of nitrite/nitrate in biological samples
Amrita Ahluwalia
£150,000 WHRL William Harvey Research Limited
01-07-2022 - 31-12-2025
bullet iconEvaluation of Sirolimus Drug Eluting Balloon(SELUTION SLRTM)for Treatment of De-Novo Coronary Artery Disease in an All-comers Patient Population(SELUTIONCADUK-I)
Amrita Ahluwalia
£270,250 Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust
01-02-2022 - 31-05-2026
bullet iconBHF 4 Year PhD Studentships (2021 - 2024 intakes)
Amrita Ahluwalia
£444,465 BHF British Heart Foundation
01-10-2021 - 30-09-2025
bullet iconTherapeutic utility of targeting C-type natriuretic peptide to maintain endothelial integrity
Adrian Hobbs and Amrita Ahluwalia
£334,632 MRC Medical Research Council
05-10-2020 - 31-07-2025

bullet iconA Multi Site, Placebo Controlled, Double Blind Randomised Clinical Trial Evaluating The Effectiveness Of Sodium Zirconium Cyclosilicate Versus Placebo To Enable Safe Optimisation Of RASi Therapy In Patients With Diabetic Kidney Disease QM
Amrita Ahluwalia
£217,020 BH NHS Barts Health NHS
01-04-2022 - 30-09-2024
bullet iconDiNOmo-HF Crowdfunding: Investigation of Dietary Nitrate Optimisation by hyperuricaeamia stratification of Heart Failure
Amrita Ahluwalia and Christopher Primus
£5,000 Barts and the London Charity
01-01-2021 - 31-12-2021
bullet iconBHF 4-Year PhD Studentship Award
Amrita Ahluwalia
£594,796 BHF British Heart Foundation
01-10-2020 - 30-09-2024
bullet iconTherapeutics or Clinical Pharmacology- Krishnaraj Sinhji Rathod
Amrita Ahluwalia
£507,914 NIHR National Institute for Health Research
02-10-2019 - 01-10-2023
bullet iconBHF 4-Year PhD Studentship Award (3rd Intake 2019 OF 4th Scheme)
Amrita Ahluwalia
£653,416 BHF British Heart Foundation
01-10-2019 - 30-09-2023
bullet iconA Multi site, placebo controlled, double blind randomised clinical trial evaluating the effectiveness of sodium zirconium cyclosilicate versus placebo to enable safe optimisation of RASi therapy in patients with diabetic kidney disease.
Kieran McCafferty and Amrita Ahluwalia
£559,581 AZ AstraZeneca UK Limited
01-09-2019 - 31-12-2021
bullet iconInorganic nitrate treatment reduces inflammation in humans: assessment of mechanisms
Amrita Ahluwalia, Rob Krams, Federica Marelli-Berg and Jacqueline Cooper
£206,297 BHF British Heart Foundation
19-08-2019 - 18-02-2022
bullet iconAnalysis of the microbiome in patients with stable angina
Amrita Ahluwalia and Krishnaraj Rathod
£49,966 Barts and the London Charity
01-06-2019 - 31-05-2020
bullet iconA phase 2, Randomized, 3 Arm Parallel Group, Placebo and Active-Controlled Study of the Effect of PL-8177 Administered via Sub-cutaneous Injection in Healthy Male Volunteers on Inflammatory Onset and Resolution
Amrita Ahluwalia and Jesmond Dalli
£545,919 Palatin Technologies
01-05-2019 - 30-04-2022
bullet iconTRP13/17 Effect of inorganic nitrate on contrast-induced nephropathy in patients undergoing coronary angiograph/ percutaneous coronary intervention for Acute Coronary Syndrome (ACS): A randomised single-centre, double-blind placebo-controlled trial
Amrita Ahluwalia, Anthony Mathur and Daniel Jones
£144,825 HRUK Heart Research UK
25-10-2018 - 31-12-2022
bullet iconAssessment of the effects of nutritional extracts upon endothelial cell function
Amrita Ahluwalia
£95,939 WHRL William Harvey Research Limited
18-10-2018 - 31-12-2021
bullet iconBHF 4-Year PhD Studentship Award- 2nd intake
Amrita Ahluwalia
£652,264 BHF British Heart Foundation
01-10-2018 - 30-09-2022
bullet iconBHF 4-Year PhD Studentship Award
Amrita Ahluwalia
£692,452 BHF British Heart Foundation
01-10-2017 - 28-02-2022
bullet iconInvestigation of Dietary Nitrate Optimisation by hyperuricaemia
Amrita Ahluwalia and Christopher Primus
£186,644 Willoughby Trustees
01-10-2017 - 28-02-2021
bullet iconGeneration of a floxed Xdh gene knockout mourse
Amrita Ahluwalia
£39,000 Barts and the London Charity
01-08-2017 - 31-07-2018
bullet iconDelineating physiological and pathological regulatory roles for C-type natriuretic peptide in cardiac structure and function
Adrian Hobbs and Amrita Ahluwalia
£817,911 BHF British Heart Foundation
01-10-2016 - 28-02-2022
bullet iconPhenotyping of the xanthine dehydrogenase knockout mouse: effects on nitrite reduction
Amrita Ahluwalia
£41,875 WHRL William Harvey Research Limited
01-09-2015 - 31-08-2018
bullet iconCreating global leadership in cardiovascular care, research and education
Amrita Ahluwalia
£10,276,879 Barts and the London Charity
01-07-2015 - 31-03-2024