Dr Abish Stephen
Lecturer
Research
Bioreactors, Volatile Organic Compounds, Oral Microbiome, Co-culture, Microbial Ecology, Disease Biomarkers
Interests
Dr. Abish Stephen is an expert in developing microcosm bioreactors tailored for volatile metabolomics, providing insights into microbial metabolic interactions. His research focuses on elucidating the oral microbiome’s influence on local and systemic diseases, using advanced co-culture models to study ecological interactions between bacteria and fungi. By integrating genomic, transcriptomic, and metabolomic analyses of these models, Dr. Stephen is pioneering approaches to identify biomarkers for the early detection of cancer. His work bridges microbiology, bioinformatics, and systems biology, advancing understanding of the human microbiome’s role in health and disease.Publications
2024
Picolo M, Stephen A and Baysan A (2024). The antimicrobial effect of different vitamin D compounds on Streptococcus mutans and their impact on glycosyltransferase expression. Taylor & Francis Journal of Oral Microbiology vol. 16, (1) 2023
Nibali L, Stephen AS, Allaker RP, Di Pino A, Terranova V, Pisano M, Di Marca S, Ferrara V, Scicali R, Purrello F, Donos N, Regolo M and Malatino L (2023). Associations between Host Genetic Variants and Subgingival Microbiota in Patients with the Metabolic Syndrome. MDPI International Journal of Molecular Sciences vol. 24, (23) McPolin-Hall E, Stephen A, Pardieu C, Allaker R, Philpott M, Bhogal R, Pople J and Hannen R (2023). O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models. Oxford University Press (OUP) British Journal of Dermatology vol. 189, (1) e6-e6. Sadler E, Stephen AS, Allaker RP and Crick CR (2023). Engineering Biofouling Resistant Materials Through the Systematic Adaptation of Surface Morphology. Advanced Materials Interfaces vol. 10, (12) 2022
Stephen AS, Nicolas CS, Lloret F and Allaker RP (2022). In vitro effectiveness of pomegranate extract present in pet oral hygiene products against canine oral bacterial species. Veterinary World Veterinary World vol. 15, (7) 1714-1718. Nibali L, Stephen A, Hagi-Pavli E, Allaker R, Pino AD, Terranova V, Pisano M, Marca SD, Ferrara V, Scicali R, Giordano M, Purrello F, Donos N and Malatino L (2022). Analysis of gingival crevicular fluid biomarkers in patients with metabolic syndrome. Elsevier Journal of Dentistry vol. 118, 2021
Stephen AS, Dhadwal N, Nagala V, Gonzales‐Marin C, Gillam DG, Bradshaw DJ, Burnett GR and Allaker RP (2021). Interdental and subgingival microbiota may affect the tongue microbial ecology and oral malodour in health, gingivitis and periodontitis. Wiley Journal of Periodontal Research vol. 56, (6) 1174-1184. Karen-Ng LP, James EL, Stephen A, Bennett MH, Mycielska ME and Parkinson EK (2021). The Extracellular Metabolome Stratifies Low and High Risk Potentially Premalignant Oral Keratinocytes and Identifies Citrate as a Potential Non-Invasive Marker of Tumour Progression. MDPI Cancers vol. 13, (16) Gillam DG, PLASTARGIAS I, Stephen A, AL-MUTAIRI R and Allaker RP (2021). The Relationship between both Partial and Complete Denture Wearers and the Presence of Oral Malodour and the Effect of Denture Cleansers on the Oral Microbiota. Advances in Dentistry & Oral Health vol. 13, (5) 2018
Yuan Z, Memarzadeh K, Stephen AS, Allaker RP, Brown RA and Huang J (2018). Development of a 3D Collagen Model for the In Vitro Evaluation of Magnetic-assisted Osteogenesis. Springer Nature Scientific Reports vol. 8, (1) Waite RD, Stewart JE, Stephen AS and Allaker RP (2018). Activity of a nitric oxide-generating wound treatment system against wound pathogen biofilms. Elsevier International Journal of Antimicrobial Agents vol. 52, (3) 338-343. 2017
Allaker RP and Stephen AS (2017). Use of Probiotics and Oral Health. SpringerLink Curr Oral Health Rep vol. 4, (4) 309-318. Stephen AS, Gonzalez-Marin C, Gillam DG, Burnett GR, Bradshaw DJ and Allaker RP (2017). The role of periodontal niches in influencing the tongue microbiota: relationship with periodontitis and oral malodour. Journal of Oral Microbiology vol. 9, (sup1) 1325201-1325201. 2016
Stephen AS, Millhouse E, Sherry L, Aduse-Opoku J, Culshaw S, Ramage G, Bradshaw DJ, Burnett GR and Allaker RP (2016). In Vitro Effect of Porphyromonas gingivalis Methionine Gamma Lyase on Biofilm Composition and Oral Inflammatory Response. Public Library of Science (PLoS) PLoS ONE vol. 11, (12) e0169157-e0169157. STEPHEN AS (2016). The relationship between Oral Malodour and Chronic Periodontitis: Role of Volatile Sulfur Compounds. 2014
Stephen AS, Naughton DP, Pizzey RL, Bradshaw DJ and Burnett GR (2014). In vitro growth characteristics and volatile sulfur compound production of Solobacterium moorei. Elsevier Anaerobe vol. 26, 53-57. 2011
Burnett GR, Stephen AS, Pizzey RL and Bradshaw DJ (2011). In vitro effects of novel toothpaste actives on components of oral malodour. Elsevier International Dental Journal vol. 61, (Suppl 3) 67-73.