Prof Conrad Bessant
Professor of Bioinformatics
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
Bioinformatics, Data science, Machine learning, Proteomics, Artificial intelligence
Publications
Publications of specific relevance to Predictive in vitro Models
2023
Branson N, Cutillas PR and Bessant C (2023). Comparison of multiple modalities for drug response prediction with learning curves using neural networks and XGBoost. Oxford University Press (OUP) Bioinformatics Advances vol. 4, (1)
Saihi H, Bessant C and Alazawi W (2023). Automated and reproducible cell identification in mass cytometry using neural networks. Oxford University Press Briefings in Bioinformatics
Elder GA and Bessant C (2023). Inferring Compensatory Kinase Networks in Yeast using Prolog. Open Publishing Association Electronic Proceedings in Theoretical Computer Science vol. 385, 260-273.
De Los Angeles Colomina Basanta C, Bazzi M, Hijazi M, Bessant C and Cutillas PR (2023). Community detection in empirical kinase networks identifies new potential members of signalling pathways. Public Library of Science (PLoS) PLOS Computational Biology vol. 19, (6)
Bessant C, Abdollahyan M and Smeraldi F (2023). CO51 Understanding the Lived Experience of Patients By Mining Online Health Boards. Elsevier Value in Health vol. 26, (6) s23-s24.
Byrom B, Bessant C, Smeraldi F, Abdollahyan M, Bridges Y, Chowdhury M and Tahsin A (2023). Deriving Meaningful Aspects of Health Related to Physical Activity in Chronic Disease: Concept Elicitation Using Machine Learning–Assisted Coding of Online Patient Conversations. Elsevier Value in Health vol. 26, (7) 1057-1066.
2022
Bessant C, Bridges Y, Chowdhury M, Tahsin A, Abdollahyan M, Smeraldi F and Byrom B (2022). PCR3 Assessing Concept Saturation and Sample Representativeness When Using Social Media Data to Inform Concept Elicitation Studies. Elsevier Value in Health vol. 25, (12)
Waller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C and Alazawi W (2022). Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease. The Korean Association for the Study of the Liver Clinical and Molecular Hepatology vol. 29, (2) 417-432.
Bridges Y, Chowdhury M, Tahsin A, Bessant C, Abdollahyan M, Smeraldi F and Byrom B (2022). POSB338 Identification of Meaningful Aspects of Physical Activity: Concept Elicitation By AI-Assisted Coding of Online Patient Conversations. Elsevier Value in Health vol. 25, (1)
2021
Patel R, Smeraldi F, Abdollahyan M, Irving J and Bessant C (2021). Analysis of mental and physical disorders associated with COVID-19 in online health forums: a natural language processing study. BMJ BMJ Open vol. 11, (11)
2020
Gomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C and Dalli J (2020). Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Springer Nature Nature Communications vol. 11, (1)
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C (2020). Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. Nature Research (part of Springer Nature) npj Breast Cancer vol. 6, (1)
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C (2020). Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. NPJ Breast Cancer vol. 6, (1)
Hijazi M, Smith R, Rajeeve V, Bessant C and Cutillas PR (2020). Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring. Nature Research Nature Biotechnology
2018
Saha S, Matthews DA and Bessant C (2018). High throughput discovery of protein variants using proteomics informed by transcriptomics. Oxford University Press (OUP) Nucleic Acids Research vol. 46, (10)
2017
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, Cutillas PR, Lockley M, Bessant C, Knight M and Balkwill FR (2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov
SAHA S, Chatzimichali E, Matthews D and Bessant C (2017). PITDB: a database of translated genomic elements. Oxford University Press Nucleic Acids Research
Maringer K, Yousuf A, Heesom KJ, Fan J, Lee D, Fernandez-Sesma A, Bessant C, Matthews DA and Davidson AD (2017). Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti. BMC Genomics vol. 18, (1) 101-101.
Bessant C (2017). Acknowledgements. New Developments in Mass Spectrometry vol. 2017-January, (5)
2016
Saha S, Matthews D and Bessant C (2016). Chapter 16 Proteomics Informed by Transcriptomics. Proteome Informatics Royal Society of Chemistry (RSC)
Bessant C (2016). Chapter 1 Introduction to Proteome Informatics. Proteome Informatics Royal Society of Chemistry (RSC)
(2016). Proteome Informatics., Editors: Bessant C. The Royal Society of Chemistry
Walton C, Montoya MPB, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C, Naylor SJ and Hunter JO (2016). Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational study. Nature Publishing Group: Open Access Hybrid Model Option B European Journal of Clinical Nutrition vol. 70, 1052-1056.
Cauchi M, Weber CM, Bolt BJ, Spratt PB, Bessant C, Turner DC, Willis CM, Britton LE, Turner C and Morgan G (2016). Evaluation of gas chromatography mass spectrometry and pattern recognition for the identification of bladder cancer from urine headspace. Royal Society of Chemistry (RSC) Analytical Methods vol. 8, (20) 4037-4046.
Mohareb F, Papadopoulou O, Panagou E, Nychas G-J and Bessant C (2016). Ensemble-based support vector machine classifiers as an efficient tool for quality assessment of beef fillets from electronic nose data. Royal Society of Chemistry (RSC) Analytical Methods vol. 8, (18) 3711-3721.
2015
Chatzimichali EA and Bessant C (2015). Novel application of heuristic optimisation enables the creation and thorough evaluation of robust support vector machine ensembles for machine learning applications. Springer Nature Metabolomics vol. 12, (1)
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR (2015). The mzqLibrary - An open source Java library supporting the HUPO-PSI quantitative proteomics standard. Proteomics vol. 15, (18) 3152-3162.
Fan J, Saha S, Barker G, Heesom KJ, Ghali F, Jones AR, Matthews DA and Bessant C (2015). Galaxy Integrated Omics: Web-based Standards-Compliant Workflows for Proteomics Informed by Transcriptomics*[S]. Elsevier Molecular & Cellular Proteomics vol. 14, (11) 3087-3093.
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR (2015). The mzqLibrary – An open source Java library supporting the HUPO‐PSI quantitative proteomics standard. Wiley Proteomics vol. 15, (18) 3152-3162.
Cauchi M, Fowler DP, Walton C, Turner C, Waring RH, Ramsden DB, Hunter JO, Teale P, Cole JA and Bessant C (2015). Comparison of GC-MS, HPLC-MS and SIFT-MS in conjunction with multivariate classification for the diagnosis of Crohn's disease in urine. Royal Society of Chemistry (RSC) Analytical Methods vol. 7, (19) 8379-8385.
2014
Gonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR (2014). A tutorial for software development in quantitative proteomics using PSI standard formats. Biochim Biophys Acta vol. 1844, (1 Pt A) 88-97.
Bessant C, Oakley D and Shadforth I (2014). Building Bioinformatics Solutions. Oxford University Press
Cauchi M, Fowler DP, Walton C, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH and others (2014). Application of gas chromatography mass spectrometry (GC–MS) in conjunction with multivariate classification for the diagnosis of gastrointestinal diseases. Springer US Metabolomics vol. 10, (6) 1113-1120.
Sattlecker M, Stone N and Bessant C (2014). Current trends in machine-learning methods applied to spectroscopic cancer diagnosis. Elsevier/Science Direct TrAC Trends in Analytical Chemistry vol. 59, 17-25.
Bessant C, Oakley D and Shadforth I (2014). Building Bioinformatics Solutions 2nd Edition. Oxford University Press
Gonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR (2014). A tutorial for software development in quantitative proteomics using PSI standard formats. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS vol. 1844, (1) 88-97.
2013
Walton C, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C and Hunter JO (2013). Analysis of volatile organic compounds of bacterial origin in chronic gastrointestinal diseases. Inflamm Bowel Dis vol. 19, (10) 2069-2078.
Walzer M, Qi D, Mayer G, Uszkoreit J, Eisenacher M, Sachsenberg T, Gonzalez-Galarza FF, Fan J, Bessant C, Deutsch EW, Reisinger F, Vizcaíno JA, Medina-Aunon JA, Albar JP, Kohlbacher O and Jones AR (2013). The mzQuantML data standard for mass spectrometry-based quantitative studies in proteomics. Mol Cell Proteomics vol. 12, (8) 2332-2340.
Bessant C and Fan J (2013). Computational approaches to selected reaction monitoring assay design. Methods Mol Biol vol. 1007, 219-235.
Bessant C and Fan J (2013). Computational approaches to selected reaction monitoring assay design. Methods in Molecular Biology vol. 1007, 219-235.
2012
Evans VC, Barker G, Heesom KJ, Fan J, Bessant C and Matthews DA (2012). De novo derivation of proteomes from transcriptomes for transcript and protein identification. Nat Methods vol. 9, (12) 1207-1211.
Gonzalez-Galarza FF, Lawless C, Hubbard SJ, Fan J, Bessant C, Hermjakob H and Jones AR (2012). A critical appraisal of techniques, software packages, and standards for quantitative proteomic analysis. OMICS vol. 16, (9) 431-442.
Fan J, Mohareb F, Bond NJ, Lilley KS and Bessant C (2012). MRMaid 2.0: mining PRIDE for evidence-based SRM transitions. OMICS vol. 16, (9) 483-488.
Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH, Ramsden DB, Hunter JO, Cauchi M, Bessant C, Fowler DP, Walton C, Turner C and Cole JA (2012). Diversity and distribution of sulphate-reducing bacteria in human faeces from healthy subjects and patients with inflammatory bowel disease. FEMS Immunol Med Microbiol vol. 65, (1) 55-68.
Fan J, Mohareb F, Jones AME and Bessant C (2012). MRMaid: The SRM Assay Design Tool for Arabidopsis and Other Species. Front Plant Sci vol. 3,
2011
Thiollet S, Bessant C and Morgan SL (2011). Application of multiple response optimization design to quantum dot-encoded microsphere bioconjugates hybridization assay. Anal Biochem vol. 414, (1) 23-30.
Panagou EZ, Mohareb FR, Argyri AA, Bessant CM and Nychas G-JE (2011). A comparison of artificial neural networks and partial least squares modelling for the rapid detection of the microbial spoilage of beef fillets based on Fourier transform infrared spectral fingerprints. Food Microbiol vol. 28, (4) 782-790.
Weber CM, Cauchi M, Patel M, Bessant C, Turner C, Britton LE and Willis CM (2011). Evaluation of a gas sensor array and pattern recognition for the identification of bladder cancer from urine headspace. Analyst vol. 136, (2) 359-364.
Johnson PE, Baumgartner S, Aldick T, Bessant C, Giosafatto V, Heick J, Mamone G, O'Connor G, Poms R, Popping B, Reuter A, Ulberth F, Watson A, Monaci L and Mills ENC (2011). Current perspectives and recommendations for the development of mass spectrometry methods for the determination of allergens in foods. J AOAC Int vol. 94, (4) 1026-1033.
Cauchi M, Bianco L and Bessant C (2011). The quantification of pollutants in drinking water by use of artificial neural networks. Nat. Comput. vol. 10, 77-90.
Sattlecker M, Baker R, Stone N and Bessant C (2011). Support vector machine ensembles for breast cancer type prediction from mid-FTIR micro-calcification spectra. Elsevier Chemometrics and Intelligent Laboratory Systems vol. 107, 363-370.
Sattlecker M, Stone N, Smith J and Bessant C (2011). Assessment of robustness and transferability of classification models built for cancer diagnostics using Raman spectroscopy. Wiley Online Library Journal of Raman Spectroscopy vol. 42, 897-903.
Bessant C (2011). Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data Darius M. Dziuda John Wiley and Sons, 2010, p. 327 ISBN: 978-0-470-16373-3. WILEY-VCH Verlag Proteomics vol. 11, 3768-3768.
Bessant C (2011). Experiences in Pattern Recognition for Machine Olfaction. American Institute of Physics
2010
Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and Reither K (2010). Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis. J Clin Microbiol vol. 48, (11) 4235-4238.
Sattlecker M, Bessant C, Smith J and Stone N (2010). Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics. Analyst vol. 135, (5) 895-901.
Cham Mead JA, Bianco L and Bessant C (2010). Free computational resources for designing selected reaction monitoring transitions. Proteomics vol. 10, (6) 1106-1126.
Chem Mead JA, Bianco L and Bessant C (2010). Mining proteomic MS/MS data for MRM transitions. Methods Mol Biol vol. 604, 187-199.
Cham JA, Bianco L, Barton C and Bessant C (2010). MRMaid-DB: a repository of published SRM transitions. J Proteome Res vol. 9, (1) 620-625.
Tetsuya H (2010). Discerning data analysis methods to clarify agonistic/antagonistic actions on the ion flux assay of ligand-gated ionotropic glutamate receptor on engineered post-synapse model cells. Journal of Biosensors & Bioelectronics
Tanoue C, Asakawa H, Cauchi M, Bessant C, Ikeno S and Haruyama T (2010). Tissular model/sensor seamless system for qualified analysis and its characterization. Elsevier Biochemical Engineering Journal vol. 52, 110-115.
Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and others (2010). Electronic-nose technology in diagnosis of TB patients using sputum samples. Am Soc Microbiol Journal of Clinical Microbiology
2009
Spooner AD, Bessant C, Turner C, Knobloch H and Chambers M (2009). Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers. Analyst vol. 134, (9) 1922-1927.
Blanco L, Mead JA and Bessant C (2009). Comparison of novel decoy database designs for optimizing protein identification searches using ABRF sPRG2006 standard MS/MS data sets. J Proteome Res vol. 8, (4) 1782-1791.
Babrah J, McCarthy K, Lush RJ, Rye AD, Bessant C and Stone N (2009). Fourier transform infrared spectroscopic studies of T-cell lymphoma, B-cell lymphoid and myeloid leukaemia cell lines. Analyst vol. 134, (4) 763-768.
Mead JA, Bianco L, Ottone V, Barton C, Kay RG, Lilley KS, Bond NJ and Bessant C (2009). MRMaid, the web-based tool for designing multiple reaction monitoring (MRM) transitions. Mol Cell Proteomics vol. 8, (4) 696-705.
Moczko E, Meglinski IV, Bessant C and Piletsky SA (2009). Dyes assay for measuring physicochemical parameters. Anal Chem vol. 81, (6) 2311-2316.
Mead JA, Bianco L and Bessant C (2009). Recent developments in public proteomic MS repositories and pipelines. Proteomics vol. 9, (4) 861-881.
Thanaraj T, Terry LA and Bessant C (2009). Chemometric profiling of pre-climacteric Sri Lankan mango fruit (< i> Mangifera indica L.). Elsevier Food Chemistry vol. 112, 786-794.
Tottey S, Robinson N, Waldron K, Firbank S and Bessant C (2009). Protein folding location determines binding of manganese versus copper. Pergamon Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology vol. 153, S159-S159.
2008
Robinson N, Waldron K, Tottey S and Bessant C (2008). Metalloprotein metal pools: identification and quantification by coupling native and non-native separations through principal component analysis. Springer Nature Protocol Exchange
Tottey S, Waldron KJ, Firbank SJ, Reale B, Bessant C, Sato K, Cheek TR, Gray J, Banfield MJ, Dennison C and Robinson NJ (2008). Protein-folding location can regulate manganese-binding versus copper- or zinc-binding. Nature vol. 455, (7216) 1138-1142.
Stott W, Ryan A, Jacobs IJ, Menon U, Bessant C and Jones C (2008). OSPACS: Ultrasound image management system. Source Code Biol Med vol. 3,
Cauchi M, Bessant C and Setford S (2008). Simultaneous Quantitative Determination of Cadmium, Lead, and Copper on Carbon-Ink Screen-Printed Electrodes by Differential Pulse Anodic Stripping Voltammetry and Partial Least Squares Regression. Wiley Online Library Electroanalysis vol. 20, 2571-2577.
Mead J, Bianco L and Bessant C (2008). Using Bioinformatics to Increase Speed and Reduce Uncertainty in Protein Biomarker Discovery. Cranfield Multi-Strand Conference: Creating Wealth Through Research and Innovation vol. 6, 118-118.
2007
Mead JA, Shadforth IP and Bessant C (2007). Public proteomic MS repositories and pipelines: available tools and biological applications. Proteomics vol. 7, (16) 2769-2786.
Goodacre R, Broadhurst D, Smilde AK, Kristal BS, Baker JD, Beger R, Bessant C, Connor S, Capuani G, Craig A and others (2007). Proposed minimum reporting standards for data analysis in metabolomics. Springer US Metabolomics vol. 3, 231-241.
Bessant C (2007). Microarray Analysis Software and its Applications. John Wiley & Sons, Ltd Handbook of Biosensors and Biochips
Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N (2007). FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines [6628-28]. International Society for Optical Engineering; 1999 PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING vol. 6628, 6628-6628.
Kumuthini J, Bessant C, Wilson P and Crowther D (2007). Gene regulatory network of human adipocyte differentiation. BioMed Central Ltd BMC Systems Biology vol. 1, P57-P57.
Kumuthini J, Jouffe L and Bessant C (2007). Session 1-Microarray and Systems Biology I (Networks)-A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data. Lecture Notes in Computer Science vol. 4414, 28-28.
2006
Shadforth I and Bessant C (2006). Genome annotating proteomics pipelines: available tools. Expert Rev Proteomics vol. 3, (6) 621-629.
Shadforth I, Xu W, Crowther D and Bessant C (2006). GAPP: a fully automated software for the confident identification of human peptides from tandem mass spectra. J Proteome Res vol. 5, (10) 2849-2852.
Ernst W, Trummer E, Mead J, Bessant C, Strelec H, Katinger H and Hesse F (2006). Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells. Biotechnol J vol. 1, (6) 639-650.
Fend R, Kolk AHJ, Bessant C, Buijtels P, Klatser PR and Woodman AC (2006). Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum. J Clin Microbiol vol. 44, (6) 2039-2045.
Dunkley TPJ, Hester S, Shadforth IP, Runions J, Weimar T, Hanton SL, Griffin JL, Bessant C, Brandizzi F, Hawes C, Watson RB, Dupree P and Lilley KS (2006). Mapping the Arabidopsis organelle proteome. Proc Natl Acad Sci U S A vol. 103, (17) 6518-6523.
Saini S, Bessant C, Lee-davey J and Malecha MM (2006). VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS.
Sadowski PG, Dunkley TPJ, Shadforth IP, Dupree P, Bessant C, Griffin JL and Lilley KS (2006). Quantitative proteomic approach to study subcellular localization of membrane proteins. Nat Protoc vol. 1, (4) 1778-1789.
Lilley KS, Hawes C, Hanton SL, Dunkley TPJ, Runions J, Hester S, Weimar T, Shadforth IP, Bessant C, Dupree P and others (2006). Mapping the Arabidopsis organelle proteome. Editor no identificado Proceedings of the National Academy of Sciences of the United States of America 6518-6523.
2005
Shadforth I, Crowther D and Bessant C (2005). Protein and peptide identification algorithms using MS for use in high-throughput, automated pipelines. Proteomics vol. 5, (16) 4082-4095.
Shadforth IP, Dunkley TPJ, Lilley KS and Bessant C (2005). i-Tracker: for quantitative proteomics using iTRAQ. BMC Genomics vol. 6,
Shadforth I, Todd K, Crowther D and Bessant C (2005). Determination of partial amino acid composition from tandem mass spectra for use in peptide identification strategies. Proteomics vol. 5, (7) 1787-1796.
SAINI S, BESSANT C, LEE-DAVEY J, MALECHA M and others (2005). VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS.
Shadforth I, Dunkley T, Lilley K, Crowther D and Bessant C (2005). Confident protein identification using the average peptide score method coupled with search-specific, ab initio thresholds. Rapid Commun Mass Spectrom vol. 19, (22) 3363-3368.
Mead JA, Bianco L and Bessant C (2005). the focus of attention in financial reporting. Abacus
2004
Fend R, Bessant C, Williams AJ and Woodman AC (2004). Monitoring haemodialysis using electronic nose and chemometrics. Biosens Bioelectron vol. 19, (12) 1581-1590.
Saini S, Bessant C, Lee-Davey J and Malecha MM (2004). Voltammetric detection of metabolites in physiological fluids. Google Patents
Richards E, Bessant C and Saini S (2004). Simultaneous quantification of analytes in quaternary mixtures using dual pulse staircase voltammetry and genetically optimised neural networks. Analyst vol. 129, (4) 355-358.
Saini S, Bessant C, Liedtke C and Leiferkus J (2004). DIAGNOSIS BY SENSING VOLATILE COMPONENTS.
2003
Malecha M, Bessant C and Saini S (2003). Identification of oil contaminants on polymer coated beverage cans using fluorescence spectroscopy. Appl Spectrosc vol. 57, (8) 1042-1048.
Richards E, Bessant C and Saini S (2003). A liquid handling system for the automated acquisition of data for training, validating and testing calibration models. Elsevier Sensors and Actuators B: Chemical vol. 88, 149-154.
Bessant C and Richards E (2003). Neural networks for the calibration of voltammetric data. Elsevier Nature-inspired methods in chemometrics: genetic algorithms and artificial neural networks: genetic algorithms and artificial ne vol. 23, 257-257.
2002
SAINI S, BESSANT C, LIEDTKE C, LEIFERKUS J and others (2002). DIAGNOSIS BY SENSING VOLATILE COMPONENTS.
Malecha M, Bessant C and Saini S (2002). Principal components analysis for the visualisation of multidimensional chemical data acquired by scanning Raman microspectroscopy. Analyst vol. 127, (9) 1261-1266.
Saini S, Bessant C, Liedtke C and Leiferkus J (2002). Diagnosis by sensing volatile components. Google Patents
Richards E, Bessant C and Saini S (2002). Multivariate data analysis in electroanalytical chemistry. Wiley Online Library Electroanalysis vol. 14, 1533-1542.
Richards E, Bessant C and Saini S (2002). Optimisation of a neural network model for calibration of voltammetric data. Elsevier Chemometrics and intelligent laboratory systems vol. 61, 35-49.
Malecha M, Bessant C, Perry D and Saini S (2002). Identification of oil contaminants on polymer coated beverage cans using Raman spectroscopy. Royal Society of Chemistry Analyst vol. 127, 297-303.
2001
Saini S, Barr H and Bessant C (2001). Sniffing out disease using the artificial nose. Biologist (London) vol. 48, (5) 229-233.
Bessant C, Ritchie L, Saini S, Pahlavanpour B and Wilson G (2001). Chemometric evaluation of synchronous scan fluorescence spectroscopy for the determination of regulatory conformance and usage history of insulation oils. Society for Applied Spectroscopy Applied spectroscopy vol. 55, 840-846.
2000
Ritchie LJ, Ferguson CP, Bessant C and Saini S (2000). A ten channel fibre-optic device for distributed sensing of underground hydrocarbon leakage. J Environ Monit vol. 2, (6) 670-673.
SAINI S and BESSANT C (2000). ANALYSIS OF MIXTURES.
Bessant C and Saini S (2000). A chemometric analysis of dual pulse staircase voltammograms obtained in mixtures of ethanol, fructose and glucose. Elsevier Journal of electroanalytical chemistry vol. 489, 76-83.
1999
Bessant C and Saini S (1999). Simultaneous determination of ethanol, fructose, and glucose at an unmodified platinum electrode using artificial neural networks. ACS Publications Analytical Chemistry vol. 71, 2806-2813.
Brereton R and others (1999). Integrated processing of triply coupled diode array liquid chromatography electrospray mass spectrometric signals by chemometric methods. Royal Society of Chemistry Analyst vol. 124, 1733-1744.
1997
Bessant C and Saini S (1997). An object oriented approach to electroanalytical technique implementation. Wiley Online Library Electroanalysis vol. 9, 926-931.
Grants
AI driven Omics Data Integration and Transfer Learning for Target and Biomarker Identification
Conrad Bessant
£127,935 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2024 - 30-09-2028)
Conrad Bessant
£127,935 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2024 - 30-09-2028)
BBSRC AIDD CTP CASE Award: Syed Zayyan Masud
Conrad Bessant
£21,600 Nxera Pharma UK Ltd (01-10-2024 - 30-09-2028)
Conrad Bessant
£21,600 Nxera Pharma UK Ltd (01-10-2024 - 30-09-2028)
Mechanisms underlying preterm birth in women with HIV in rural Zimbabwe
Andrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 MRC Medical Research Council (01-05-2024 - 30-04-2027)
Andrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 MRC Medical Research Council (01-05-2024 - 30-04-2027)
Martina Occhetta CTP Studentship - Exscientia Funded
Conrad Bessant and Emma Tjong
£8,600 EXSCIENTIA LIMITED (01-10-2023 - 30-09-2027)
Conrad Bessant and Emma Tjong
£8,600 EXSCIENTIA LIMITED (01-10-2023 - 30-09-2027)
TG: Target identification from multiomics data using systems biology and machine learning approaches
Conrad Bessant
£125,917 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2023 - 30-09-2027)
Conrad Bessant
£125,917 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2023 - 30-09-2027)
CTP Training Grant: Lewis Palmer
Conrad Bessant
£123,829 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2022 - 12-11-2026)
Conrad Bessant
£123,829 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2022 - 12-11-2026)
BBSRC AIDD CTP CASE Award: Lewis Palmer: “Prioritising Drug Targets in non-canonical pathways from multi-omic data
Conrad Bessant
£10,400 Merck (26-09-2022 - 25-09-2026)
Conrad Bessant
£10,400 Merck (26-09-2022 - 25-09-2026)
Survey and BIOinformatic review of fluid-tissue proteomics: novel biomarkers for ALS
Andrea Malaspina and Conrad Bessant
£188,946 Barts and the London Charity (01-09-2020 - 31-08-2025)
Andrea Malaspina and Conrad Bessant
£188,946 Barts and the London Charity (01-09-2020 - 31-08-2025)
Identifying regulatory nodes and vulnerablities of molecular networks using graph theory and machine learning analysis of proteomics data
Pedro Rodriguez Cutillas and Conrad Bessant
£45,554 Alan Turing Institute, The (01-03-2020 - 31-01-2021)
Pedro Rodriguez Cutillas and Conrad Bessant
£45,554 Alan Turing Institute, The (01-03-2020 - 31-01-2021)
Alan Turing Institute Enrichment Placement Scheme - George Elder
Conrad Bessant
£1,746 Alan Turing Institute, The (01-01-2020 - 30-06-2020)
Conrad Bessant
£1,746 Alan Turing Institute, The (01-01-2020 - 30-06-2020)
Automatic Learning in Cancer Research using Artificial Intelligence
Trevor Graham and Conrad Bessant
£178,177 Alan Turing Institute, The (01-10-2018 - 31-03-2022)
Trevor Graham and Conrad Bessant
£178,177 Alan Turing Institute, The (01-10-2018 - 31-03-2022)
Bid for MRC Industrial Strategy PhD Studentship 2018
Conrad Bessant
£93,462 MRC Medical Research Council (01-10-2018 - 31-03-2022)
Conrad Bessant
£93,462 MRC Medical Research Council (01-10-2018 - 31-03-2022)