Prof Conrad Bessant

Conrad Bessant

Professor of Bioinformatics

School of Biological and Behavioural Sciences
Queen Mary University of London
bezzlab.github.io/

Research

Bioinformatics, Data science, Machine learning, Proteomics, Artificial intelligence

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2023

Comparison of multiple modalities for drug response prediction with learning curves using neural networks and XGBoost
Branson N, Cutillas PR, Bessant C
Bioinformatics Advances, Oxford University Press (Oup) vol. 4 (1) 
23-12-2023
Automated and reproducible cell identification in mass cytometry using neural networks
Saihi H, Bessant C, Alazawi W
Briefings in Bioinformatics, Oxford University Press 
02-11-2023
Inferring Compensatory Kinase Networks in Yeast using Prolog
Elder GA, Bessant C
Electronic Proceedings in Theoretical Computer Science, Open Publishing Association vol. 385, 260-273.  
12-09-2023
Community detection in empirical kinase networks identifies new potential members of signalling pathways
De Los Angeles Colomina Basanta C, Bazzi M, Hijazi M, Bessant C, Cutillas PR
Plos Computational Biology, Public Library of Science (Plos) vol. 19 (6) 
23-06-2023
CO51 Understanding the Lived Experience of Patients By Mining Online Health Boards
Bessant C, Abdollahyan M, Smeraldi F
Value in Health, Elsevier vol. 26 (6), s23-s24.  
01-06-2023
Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease
Waller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C, Alazawi W
Clinical and Molecular Hepatology, The Korean Association For The Study of The Liver vol. 29 (2), 417-432.  
01-04-2023
Deriving Meaningful Aspects of Health Related to Physical Activity in Chronic Disease: Concept Elicitation Using Machine Learning–Assisted Coding of Online Patient Conversations
Byrom B, Bessant C, Smeraldi F, Abdollahyan M, Bridges Y, Chowdhury M, Tahsin A
Value in Health, Elsevier vol. 26 (7), 1057-1066.  
16-02-2023

2022

PCR3 Assessing Concept Saturation and Sample Representativeness When Using Social Media Data to Inform Concept Elicitation Studies
Bessant C, Bridges Y, Chowdhury M, Tahsin A, Abdollahyan M, Smeraldi F, Byrom B
Value in Health, Elsevier vol. 25 (12) 
01-12-2022
POSB338 Identification of Meaningful Aspects of Physical Activity: Concept Elicitation By AI-Assisted Coding of Online Patient Conversations
Bridges Y, Chowdhury M, Tahsin A, Bessant C, Abdollahyan M, Smeraldi F, Byrom B
Value in Health, Elsevier vol. 25 (1) 
01-01-2022

2021

Analysis of mental and physical disorders associated with COVID-19 in online health forums: a natural language processing study
Patel R, Smeraldi F, Abdollahyan M, Irving J, Bessant C
Bmj Open, Bmj vol. 11 (11) 
01-11-2021

2020

Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
Gomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C, Dalli J
Nature Communications, Springer Science and Business Media Llc vol. 11 (1) 
27-10-2020
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al.
Npj Breast Cancer, Nature Research (Part of Springer Nature) vol. 6 (1) 
21-08-2020
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer.
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al.
Npj Breast Cancer vol. 6 (1) 
21-08-2020
Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring
Hijazi M, Smith R, Rajeeve V, Bessant C, Cutillas PR
Nature Biotechnology, Nature Research 
20-01-2020
Investigating Comorbidity of Mental and Physical Disorders in Online Health Forums
Abdollahyan M, Smeraldi F, Patel R, Bessant C
Proceedings of the 3rd International Conference on Applications of Intelligent Systems. 
07-01-2020

2019

Abstract C088: Chemical phosphoproteomics systematically identifies circuitries of kinase networks in cancer cells and predicts their response to kinase inhibitors
Cutillas PR, Hijazi M, Smith R, Bessant C, Britton D
 
01-12-2019

2018

THU0052 A circulating protein signature correlates with synovial pathotypes in rheumatoid arthritis patients
Ruiz-Romero C, Picchi F, Fernández-Puente P, González-Rodríguez L, Hands R, Calamia V, Camacho-Encina M, Bessant C et al.
 
01-06-2018
SAT0074 Identification of a protein panel useful for the prediction of response to methotrexate in rheumatoid arthritis patients
Ruiz-Romero C, Picchi F, González-Rodríguez L, Fernández-Puente P, Hands R, Calamia V, Camacho-Encina M, Bessant C et al.
 
01-06-2018
High throughput discovery of protein variants using proteomics informed by transcriptomics
Saha S, Matthews DA, Bessant C
Nucleic Acids Research, Oxford University Press (Oup) vol. 46 (10) 
30-04-2018
Visualising the Topological Structure of Health-Related Message Board User Networks
Abdollahyan Maryam, Mondragón Raúl J., Bessant Conrad, Smeraldi Fabrizio
 
01-01-2018
Identification of a Panel of Circulating Proteins Associated to Synovial Pathotypes in Early Rheumatoid Arthritis Patients
Ruiz-Romero C, Picchi F, Fernandez P, Gonzalez L, Hands R, Calamia V, Camacho M, Bessant C et al.
 
01-01-2018
Identification of a Protein Profile Useful to Predict Response to Methotrexate in Early Rheumatoid Arthritis Patients
Ruiz-Romero C, Picchi F, Gonzalez L, Hands R, Calamia V, Fernandez P, Camacho M, Paz R et al.
 
01-01-2018

2017

Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers.
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al.
Cancer Discov 
01-12-2017
PITDB: a database of translated genomic elements
SAHA S, Chatzimichali E, Matthews D, Bessant C
Nucleic Acids Research, Oxford University Press 
09-10-2017
Abstract 5558: Deconstruction of a human tumor microenvironment
Balkwill FR, Pearce OM, Delaine-Smith R, Maniati E, Nichols S, Wang J, Bessant C, Knight M
 
01-07-2017
Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti.
Maringer K, Yousuf A, Heesom KJ, Fan J, Lee D, Fernandez-Sesma A, Bessant C, Matthews DA et al.
Bmc Genomics vol. 18 (1), 101-101.  
19-01-2017
Acknowledgements
Bessant C
New Developments in Mass Spectrometry vol. 2017-January (5) 
01-01-2017

2016

Chapter 16 Proteomics Informed by Transcriptomics
Saha S, Matthews D, Bessant C
In Proteome Informatics, Royal Society of Chemistry (Rsc) 385-405.  
15-11-2016
Chapter 1 Introduction to Proteome Informatics
Bessant C
In Proteome Informatics, Royal Society of Chemistry (Rsc) 1-14.  
15-11-2016
Proteome Informatics

 
15-11-2016
Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational study
Walton C, Montoya MPB, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Waring RH et al.
European Journal of Clinical Nutrition, Nature Publishing Group: Open Access Hybrid Model Option B vol. 70, 1052-1056.  
11-05-2016
Evaluation of gas chromatography mass spectrometry and pattern recognition for the identification of bladder cancer from urine headspace
Cauchi M, Weber CM, Bolt BJ, Spratt PB, Bessant C, Turner DC, Willis CM, Britton LE et al.
Analytical Methods, Royal Society of Chemistry (Rsc) vol. 8 (20), 4037-4046.  
01-01-2016
Ensemble-based support vector machine classifiers as an efficient tool for quality assessment of beef fillets from electronic nose data
Mohareb F, Papadopoulou O, Panagou E, Nychas G-J, Bessant C
Analytical Methods, Royal Society of Chemistry (Rsc) vol. 8 (18), 3711-3721.  
01-01-2016

2015

Novel application of heuristic optimisation enables the creation and thorough evaluation of robust support vector machine ensembles for machine learning applications
Chatzimichali EA, Bessant C
Metabolomics, Springer Nature vol. 12 (1) 
21-11-2015
The mzqLibrary - An open source Java library supporting the HUPO-PSI quantitative proteomics standard
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S et al.
Proteomics vol. 15 (18), 3152-3162.  
01-09-2015
Galaxy Integrated Omics: Web-based Standards-Compliant Workflows for Proteomics Informed by Transcriptomics*[S]
Fan J, Saha S, Barker G, Heesom KJ, Ghali F, Jones AR, Matthews DA, Bessant C
Molecular & Cellular Proteomics, Elsevier vol. 14 (11), 3087-3093.  
12-08-2015
The mzqLibrary – An open source Java library supporting the HUPO‐PSI quantitative proteomics standard
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S et al.
Proteomics, Wiley vol. 15 (18), 3152-3162.  
14-07-2015
Comparison of GC-MS, HPLC-MS and SIFT-MS in conjunction with multivariate classification for the diagnosis of Crohn's disease in urine
Cauchi M, Fowler DP, Walton C, Turner C, Waring RH, Ramsden DB, Hunter JO, Teale P et al.
Analytical Methods, Royal Society of Chemistry (Rsc) vol. 7 (19), 8379-8385.  
01-01-2015

2014

A tutorial for software development in quantitative proteomics using PSI standard formats.
Gonzalez-Galarza FF, Qi D, Fan J, Bessant C, Jones AR
Biochim Biophys Acta vol. 1844 (1 Pt A), 88-97.  
01-01-2014
Building Bioinformatics Solutions
Bessant C, Oakley D, Shadforth I
 
01-01-2014
Current trends in machine-learning methods applied to spectroscopic cancer diagnosis
Sattlecker M, Stone N, Bessant C
Trac Trends in Analytical Chemistry, Elsevier/Science Direct vol. 59, 17-25.  
01-01-2014
Application of gas chromatography mass spectrometry (GC–MS) in conjunction with multivariate classification for the diagnosis of gastrointestinal diseases
Cauchi M, Fowler DP, Walton C, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C et al.
Metabolomics, Springer Us vol. 10 (6), 1113-1120.  
01-01-2014
Building Bioinformatics Solutions 2nd Edition
Bessant C, Oakley D, Shadforth I
 
01-01-2014
A tutorial for software development in quantitative proteomics using PSI standard formats
Gonzalez-Galarza FF, Qi D, Fan J, Bessant C, Jones AR
Biochimica Et Biophysica Acta-Proteins and Proteomics vol. 1844 (1), 88-97.  
01-01-2014

2013

Analysis of volatile organic compounds of bacterial origin in chronic gastrointestinal diseases.
Walton C, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Waring RH et al.
Inflamm Bowel Dis vol. 19 (10), 2069-2078.  
01-09-2013
The mzQuantML data standard for mass spectrometry-based quantitative studies in proteomics.
Walzer M, Qi D, Mayer G, Uszkoreit J, Eisenacher M, Sachsenberg T, Gonzalez-Galarza FF, Fan J et al.
Mol Cell Proteomics vol. 12 (8), 2332-2340.  
01-08-2013
Computational approaches to selected reaction monitoring assay design.
Bessant C, Fan J
Methods Mol Biol vol. 1007, 219-235.  
01-01-2013
Computational approaches to selected reaction monitoring assay design
Bessant C, Fan J
Methods in Molecular Biology vol. 1007, 219-235.  
01-01-2013

2012

De novo derivation of proteomes from transcriptomes for transcript and protein identification.
Evans VC, Barker G, Heesom KJ, Fan J, Bessant C, Matthews DA
Nat Methods vol. 9 (12), 1207-1211.  
01-12-2012
A critical appraisal of techniques, software packages, and standards for quantitative proteomic analysis.
Gonzalez-Galarza FF, Lawless C, Hubbard SJ, Fan J, Bessant C, Hermjakob H, Jones AR
Omics vol. 16 (9), 431-442.  
01-09-2012
MRMaid 2.0: mining PRIDE for evidence-based SRM transitions.
Fan J, Mohareb F, Bond NJ, Lilley KS, Bessant C
Omics vol. 16 (9), 483-488.  
01-09-2012
Diversity and distribution of sulphate-reducing bacteria in human faeces from healthy subjects and patients with inflammatory bowel disease.
Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH, Ramsden DB, Hunter JO et al.
Fems Immunol Med Microbiol vol. 65 (1), 55-68.  
01-06-2012
Colorimetric analysis of agonistic/antagonistic actions on estrogen receptor using peptide-functionalized gold nanoparticle sensor
Ikeno S, Sano K, Cauchi M, Takatsuji Y, Bessant C, Haruyama T
 
17-05-2012
MRMaid: The SRM Assay Design Tool for Arabidopsis and Other Species.
Fan J, Mohareb F, Jones AME, Bessant C
Front Plant Sci vol. 3 
01-01-2012

2011

Application of multiple response optimization design to quantum dot-encoded microsphere bioconjugates hybridization assay.
Thiollet S, Bessant C, Morgan SL
Anal Biochem vol. 414 (1), 23-30.  
01-07-2011
A comparison of artificial neural networks and partial least squares modelling for the rapid detection of the microbial spoilage of beef fillets based on Fourier transform infrared spectral fingerprints.
Panagou EZ, Mohareb FR, Argyri AA, Bessant CM, Nychas G-JE
Food Microbiol vol. 28 (4), 782-790.  
01-06-2011
Evaluation of a gas sensor array and pattern recognition for the identification of bladder cancer from urine headspace.
Weber CM, Cauchi M, Patel M, Bessant C, Turner C, Britton LE, Willis CM
Analyst vol. 136 (2), 359-364.  
21-01-2011
Current perspectives and recommendations for the development of mass spectrometry methods for the determination of allergens in foods.
Johnson PE, Baumgartner S, Aldick T, Bessant C, Giosafatto V, Heick J, Mamone G, O'Connor G et al.
J Aoac Int vol. 94 (4), 1026-1033.  
01-01-2011
The quantification of pollutants in drinking water by use of artificial neural networks.
Cauchi M, Bianco L, Bessant C
Nat. Comput. vol. 10, 77-90.  
01-01-2011
Support vector machine ensembles for breast cancer type prediction from mid-FTIR micro-calcification spectra
Sattlecker M, Baker R, Stone N, Bessant C
Chemometrics and Intelligent Laboratory Systems, Elsevier vol. 107, 363-370.  
01-01-2011
Assessment of robustness and transferability of classification models built for cancer diagnostics using Raman spectroscopy
Sattlecker M, Stone N, Smith J, Bessant C
Journal of Raman Spectroscopy, Wiley Online Library vol. 42, 897-903.  
01-01-2011
Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data Darius M. Dziuda John Wiley and Sons, 2010, p. 327 ISBN: 978-0-470-16373-3
Bessant C
Proteomics, Wiley-Vch Verlag vol. 11, 3768-3768.  
01-01-2011
Experiences in Pattern Recognition for Machine Olfaction
Bessant C
, American Institute of Physics 
01-01-2011

2010

Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis.
Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S et al.
J Clin Microbiol vol. 48 (11), 4235-4238.  
01-11-2010
Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics.
Sattlecker M, Bessant C, Smith J, Stone N
Analyst vol. 135 (5), 895-901.  
01-05-2010
Free computational resources for designing selected reaction monitoring transitions.
Cham Mead JA, Bianco L, Bessant C
Proteomics vol. 10 (6), 1106-1126.  
01-03-2010
Linking Bistable Dynamics to Metabolic P Systems
Pagliarini R, Bianco L, Manca V, Bessant C
Eighth Brainstorming Week on Membrane Computing Universidad de Sevilla, Seville, Spain 1 Feb 2010 - 5 Feb 2010. 
05-02-2010
Mining proteomic MS/MS data for MRM transitions.
Chem Mead JA, Bianco L, Bessant C
Methods Mol Biol vol. 604, 187-199.  
01-01-2010
MRMaid-DB: a repository of published SRM transitions.
Cham JA, Bianco L, Barton C, Bessant C
J Proteome Res vol. 9 (1), 620-625.  
01-01-2010
Discerning data analysis methods to clarify agonistic/antagonistic actions on the ion flux assay of ligand-gated ionotropic glutamate receptor on engineered post-synapse model cells
Tetsuya H
Journal of Biosensors & Bioelectronics 
01-01-2010
Tissular model/sensor seamless system for qualified analysis and its characterization
Tanoue C, Asakawa H, Cauchi M, Bessant C, Ikeno S, Haruyama T
Biochemical Engineering Journal, Elsevier vol. 52, 110-115.  
01-01-2010
Electronic-nose technology in diagnosis of TB patients using sputum samples
Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S et al.
Journal of Clinical Microbiology, Am Soc Microbiol 
01-01-2010
ABUNDANCE OF SULPHATE REDUCING BACTERIA IN INFLAMMATORY BOWEL DISEASE
Jia W, Griffiths L, Whitehead B, Basser SJ, Dawson C, Turner C, Bessant C, Fowler D et al.
 
01-01-2010

2009

Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers.
Spooner AD, Bessant C, Turner C, Knobloch H, Chambers M
Analyst vol. 134 (9), 1922-1927.  
01-09-2009
Comparison of novel decoy database designs for optimizing protein identification searches using ABRF sPRG2006 standard MS/MS data sets.
Blanco L, Mead JA, Bessant C
J Proteome Res vol. 8 (4), 1782-1791.  
01-04-2009
Fourier transform infrared spectroscopic studies of T-cell lymphoma, B-cell lymphoid and myeloid leukaemia cell lines.
Babrah J, McCarthy K, Lush RJ, Rye AD, Bessant C, Stone N
Analyst vol. 134 (4), 763-768.  
01-04-2009
MRMaid, the web-based tool for designing multiple reaction monitoring (MRM) transitions.
Mead JA, Bianco L, Ottone V, Barton C, Kay RG, Lilley KS, Bond NJ, Bessant C
Mol Cell Proteomics vol. 8 (4), 696-705.  
01-04-2009
Dyes assay for measuring physicochemical parameters.
Moczko E, Meglinski IV, Bessant C, Piletsky SA
Anal Chem vol. 81 (6), 2311-2316.  
15-03-2009
Recent developments in public proteomic MS repositories and pipelines.
Mead JA, Bianco L, Bessant C
Proteomics vol. 9 (4), 861-881.  
01-02-2009
Development of a Workflow for Protein Sequence Analysis Based on the Taverna Workbench Software.
Monteiro MB, Pintado ME, Malcata FX, Bessant C, Moreira PR
 
01-01-2009
Chemometric profiling of pre-climacteric Sri Lankan mango fruit (< i> Mangifera indica L.)
Thanaraj T, Terry LA, Bessant C
Food Chemistry, Elsevier vol. 112, 786-794.  
01-01-2009
Protein folding location determines binding of manganese versus copper
Tottey S, Robinson N, Waldron K, Firbank S, Bessant C
Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology, Pergamon vol. 153, S159-S159.  
01-01-2009

2008

Metalloprotein metal pools: identification and quantification by coupling native and non-native separations through principal component analysis
Robinson N, Waldron K, Tottey S, Bessant C
Protocol Exchange, Springer Nature 
12-11-2008
Protein-folding location can regulate manganese-binding versus copper- or zinc-binding.
Tottey S, Waldron KJ, Firbank SJ, Reale B, Bessant C, Sato K, Cheek TR, Gray J et al.
Nature vol. 455 (7216), 1138-1142.  
23-10-2008
OSPACS: Ultrasound image management system.
Stott W, Ryan A, Jacobs IJ, Menon U, Bessant C, Jones C
Source Code Biol Med vol. 3 
20-06-2008
Simultaneous Quantitative Determination of Cadmium, Lead, and Copper on Carbon-Ink Screen-Printed Electrodes by Differential Pulse Anodic Stripping Voltammetry and Partial Least Squares Regression
Cauchi M, Bessant C, Setford S
Electroanalysis, Wiley Online Library vol. 20, 2571-2577.  
01-01-2008
Using Bioinformatics to Increase Speed and Reduce Uncertainty in Protein Biomarker Discovery
Mead J, Bianco L, Bessant C
Cranfield Multi-Strand Conference: Creating Wealth Through Research and Innovation vol. 6, 118-118.  
01-01-2008

2007

Public proteomic MS repositories and pipelines: available tools and biological applications.
Mead JA, Shadforth IP, Bessant C
Proteomics vol. 7 (16), 2769-2786.  
01-08-2007
FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines
Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C, Stone N
Diagnostic Optical Spectroscopy in Biomedicine IV. 
05-07-2007
A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data.
Kumuthini J, Jouffe L, Bessant C
 
01-01-2007
Proposed minimum reporting standards for data analysis in metabolomics
Goodacre R, Broadhurst D, Smilde AK, Kristal BS, Baker JD, Beger R, Bessant C, Connor S et al.
Metabolomics, Springer Us vol. 3, 231-241.  
01-01-2007
Microarray Analysis Software and its Applications
Bessant C
Handbook of Biosensors and Biochips, John Wiley & Sons, Ltd 
01-01-2007
FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines [6628-28]
Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C, Stone N
Proceedings-Spie The International Society For Optical Engineering, International Society For Optical Engineering; 1999 vol. 6628, 6628-6628.  
01-01-2007
FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines
Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C, Stone N
 
01-01-2007
Gene regulatory network of human adipocyte differentiation
Kumuthini J, Bessant C, Wilson P, Crowther D
Bmc Systems Biology, Biomed Central Ltd vol. 1, P57-P57.  
01-01-2007
Session 1-Microarray and Systems Biology I (Networks)-A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data
Kumuthini J, Jouffe L, Bessant C
Lecture Notes in Computer Science vol. 4414, 28-28.  
01-01-2007
Fourier transform infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines
Babrah J, Lush R, Rye A, McCarthy K, Bessant C, Stone N
 
01-01-2007

2006

Genome annotating proteomics pipelines: available tools.
Shadforth I, Bessant C
Expert Rev Proteomics vol. 3 (6), 621-629.  
01-12-2006
GAPP: a fully automated software for the confident identification of human peptides from tandem mass spectra.
Shadforth I, Xu W, Crowther D, Bessant C
J Proteome Res vol. 5 (10), 2849-2852.  
01-10-2006
Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells.
Ernst W, Trummer E, Mead J, Bessant C, Strelec H, Katinger H, Hesse F
Biotechnol J vol. 1 (6), 639-650.  
01-06-2006
Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum.
Fend R, Kolk AHJ, Bessant C, Buijtels P, Klatser PR, Woodman AC
J Clin Microbiol vol. 44 (6), 2039-2045.  
01-06-2006
Mapping the Arabidopsis organelle proteome.
Dunkley TPJ, Hester S, Shadforth IP, Runions J, Weimar T, Hanton SL, Griffin JL, Bessant C et al.
Proc Natl Acad Sci U S A vol. 103 (17), 6518-6523.  
25-04-2006
VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS
Saini S, Bessant C, Lee-davey J, Malecha MM
 
22-03-2006
Quantitative proteomic approach to study subcellular localization of membrane proteins.
Sadowski PG, Dunkley TPJ, Shadforth IP, Dupree P, Bessant C, Griffin JL, Lilley KS
Nat Protoc vol. 1 (4), 1778-1789.  
01-01-2006
Mapping the Arabidopsis organelle proteome
Lilley KS, Hawes C, Hanton SL, Dunkley TPJ, Runions J, Hester S, Weimar T, Shadforth IP et al.
Proceedings of The National Academy of Sciences of The United States of America, Editor No Identificado, 6518-6523.  
01-01-2006

2005

Protein and peptide identification algorithms using MS for use in high-throughput, automated pipelines.
Shadforth I, Crowther D, Bessant C
Proteomics vol. 5 (16), 4082-4095.  
01-11-2005
i-Tracker: for quantitative proteomics using iTRAQ.
Shadforth IP, Dunkley TPJ, Lilley KS, Bessant C
Bmc Genomics vol. 6 
20-10-2005
Determination of partial amino acid composition from tandem mass spectra for use in peptide identification strategies.
Shadforth I, Todd K, Crowther D, Bessant C
Proteomics vol. 5 (7), 1787-1796.  
01-05-2005
VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS
SAINI S, BESSANT C, LEE-DAVEY J, MALECHA M, others
 
07-01-2005
Confident protein identification using the average peptide score method coupled with search-specific, ab initio thresholds.
Shadforth I, Dunkley T, Lilley K, Crowther D, Bessant C
Rapid Commun Mass Spectrom vol. 19 (22), 3363-3368.  
01-01-2005
the focus of attention in financial reporting
Mead JA, Bianco L, Bessant C
Abacus 
01-01-2005

2004

Monitoring haemodialysis using electronic nose and chemometrics.
Fend R, Bessant C, Williams AJ, Woodman AC
Biosens Bioelectron vol. 19 (12), 1581-1590.  
15-07-2004
Voltammetric detection of metabolites in physiological fluids
Saini S, Bessant C, Lee-Davey J, Malecha MM
 
28-06-2004
Simultaneous quantification of analytes in quaternary mixtures using dual pulse staircase voltammetry and genetically optimised neural networks.
Richards E, Bessant C, Saini S
Analyst vol. 129 (4), 355-358.  
01-04-2004
DIAGNOSIS BY SENSING VOLATILE COMPONENTS
Saini S, Bessant C, Liedtke C, Leiferkus J
 
14-01-2004
Search-Space Reduction of a Non-Redundant Peptide Database.
Shadforth I, Crowther D, Bessant C
 
01-01-2004
An Overview of Soft Computing Techniques Used in the Drug Discovery Process.
Oduguwa A, Tiwari A, Roy R, Bessant C
 
01-01-2004

2003

Identification of oil contaminants on polymer coated beverage cans using fluorescence spectroscopy.
Malecha M, Bessant C, Saini S
Appl Spectrosc vol. 57 (8), 1042-1048.  
01-08-2003
A liquid handling system for the automated acquisition of data for training, validating and testing calibration models
Richards E, Bessant C, Saini S
Sensors and Actuators B: Chemical, Elsevier vol. 88, 149-154.  
01-01-2003
Neural networks for the calibration of voltammetric data
Bessant C, Richards E
Nature-Inspired Methods in Chemometrics: Genetic Algorithms and Artificial Neural Networks: Genetic Algorithms and Artificial NE, Elsevier vol. 23, 257-257.  
01-01-2003

2002

DIAGNOSIS BY SENSING VOLATILE COMPONENTS
SAINI S, BESSANT C, LIEDTKE C, LEIFERKUS J, others
 
01-11-2002
Principal components analysis for the visualisation of multidimensional chemical data acquired by scanning Raman microspectroscopy.
Malecha M, Bessant C, Saini S
Analyst vol. 127 (9), 1261-1266.  
01-09-2002
Diagnosis by sensing volatile components
Saini S, Bessant C, Liedtke C, Leiferkus J
 
19-04-2002
Multivariate data analysis in electroanalytical chemistry
Richards E, Bessant C, Saini S
Electroanalysis, Wiley Online Library vol. 14, 1533-1542.  
01-01-2002
Optimisation of a neural network model for calibration of voltammetric data
Richards E, Bessant C, Saini S
Chemometrics and Intelligent Laboratory Systems, Elsevier vol. 61, 35-49.  
01-01-2002
Identification of oil contaminants on polymer coated beverage cans using Raman spectroscopy
Malecha M, Bessant C, Perry D, Saini S
Analyst, Royal Society of Chemistry vol. 127, 297-303.  
01-01-2002

2001

Simultaneous resolution of overlapping tailing peaks of Isomers using dual detector diode array liquid Chromatography electrospray mass spectrometry
Brereton RG, Bessant C
Aegean Analytical Chemistry Conference. 
31-12-2001
Sniffing out disease using the artificial nose.
Saini S, Barr H, Bessant C
Biologist (London) vol. 48 (5), 229-233.  
01-10-2001
Chemometric evaluation of synchronous scan fluorescence spectroscopy for the determination of regulatory conformance and usage history of insulation oils
Bessant C, Ritchie L, Saini S, Pahlavanpour B, Wilson G
Applied Spectroscopy, Society For Applied Spectroscopy vol. 55, 840-846.  
01-01-2001

2000

A ten channel fibre-optic device for distributed sensing of underground hydrocarbon leakage.
Ritchie LJ, Ferguson CP, Bessant C, Saini S
J Environ Monit vol. 2 (6), 670-673.  
01-12-2000
ANALYSIS OF MIXTURES
SAINI S, BESSANT C
 
14-04-2000
A chemometric analysis of dual pulse staircase voltammograms obtained in mixtures of ethanol, fructose and glucose
Bessant C, Saini S
Journal of Electroanalytical Chemistry, Elsevier vol. 489, 76-83.  
01-01-2000

1999

Simultaneous determination of ethanol, fructose, and glucose at an unmodified platinum electrode using artificial neural networks
Bessant C, Saini S
Analytical Chemistry, Acs Publications vol. 71, 2806-2813.  
01-01-1999
Integrated processing of triply coupled diode array liquid chromatography electrospray mass spectrometric signals by chemometric methods
Brereton R, others
Analyst, Royal Society of Chemistry vol. 124, 1733-1744.  
01-01-1999

1997

An object oriented approach to electroanalytical technique implementation
Bessant C, Saini S
Electroanalysis, Wiley Online Library vol. 9, 926-931.  
01-01-1997

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconAI driven Omics Data Integration and Transfer Learning for Target and Biomarker Identification
Conrad Bessant
£127,935 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2024 - 30-09-2028
bullet iconBBSRC AIDD CTP CASE Award: Syed Zayyan Masud
Conrad Bessant
£21,600 Nxera Pharma UK Ltd
01-10-2024 - 30-09-2028
solid heart iconMechanisms underlying preterm birth in women with HIV in rural Zimbabwe
Andrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 Medical Research Council
01-05-2024 - 30-04-2027
bullet iconMartina Occhetta CTP Studentship - Exscientia Funded
Conrad Bessant and Emma Tjong
£8,600 EXSCIENTIA LIMITED
01-10-2023 - 30-09-2027
bullet iconTG: Target identification from multiomics data using systems biology and machine learning approaches
Conrad Bessant
£125,917 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2023 - 30-09-2027
bullet iconCTP Training Grant: Lewis Palmer
Conrad Bessant
£123,829 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2022 - 12-11-2026
bullet iconBBSRC AIDD CTP CASE Award: Lewis Palmer: “Prioritising Drug Targets in non-canonical pathways from multi-omic data
Conrad Bessant
£10,400 Merck
26-09-2022 - 25-09-2026
bullet iconSurvey and BIOinformatic review of fluid-tissue proteomics: novel biomarkers for ALS
Andrea Malaspina and Conrad Bessant
£191,284 Barts and the London Charity
01-09-2020 - 30-09-2025

bullet iconIdentifying regulatory nodes and vulnerablities of molecular networks using graph theory and machine learning analysis of proteomics data
Pedro Rodriguez Cutillas and Conrad Bessant
£45,554 Alan Turing Institute, The
01-03-2020 - 31-01-2021
bullet iconAlan Turing Institute Enrichment Placement Scheme - George Elder
Conrad Bessant
£1,746 Alan Turing Institute, The
01-01-2020 - 30-06-2020
bullet iconAutomatic Learning in Cancer Research using Artificial Intelligence
Trevor Graham and Conrad Bessant
£178,177 Alan Turing Institute, The
01-10-2018 - 31-03-2022
bullet iconBid for MRC Industrial Strategy PhD Studentship 2018
Conrad Bessant
£93,462 MRC Medical Research Council
01-10-2018 - 31-03-2022