Prof Conrad Bessant

Conrad Bessant

Professor of Bioinformatics

School of Biological and Behavioural Sciences
Queen Mary University of London

Research

Bioinformatics, Data science, Machine learning, Proteomics, Artificial intelligence

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2023

Branson N, Cutillas PR and Bessant C (2023). Comparison of multiple modalities for drug response prediction with learning curves using neural networks and XGBoost. Oxford University Press (OUP)  Bioinformatics Advances  vol. 4, (1)  
Saihi H, Bessant C and Alazawi W (2023). Automated and reproducible cell identification in mass cytometry using neural networks. Oxford University Press  Briefings in Bioinformatics   
Elder GA and Bessant C (2023). Inferring Compensatory Kinase Networks in Yeast using Prolog. Open Publishing Association  Electronic Proceedings in Theoretical Computer Science  vol. 385, 260-273.  
De Los Angeles Colomina Basanta C, Bazzi M, Hijazi M, Bessant C and Cutillas PR (2023). Community detection in empirical kinase networks identifies new potential members of signalling pathways. Public Library of Science (PLoS)  PLOS Computational Biology  vol. 19, (6)  
Bessant C, Abdollahyan M and Smeraldi F (2023). CO51 Understanding the Lived Experience of Patients By Mining Online Health Boards. Elsevier  Value in Health  vol. 26, (6) s23-s24.  
Byrom B, Bessant C, Smeraldi F, Abdollahyan M, Bridges Y, Chowdhury M and Tahsin A (2023). Deriving Meaningful Aspects of Health Related to Physical Activity in Chronic Disease: Concept Elicitation Using Machine Learning–Assisted Coding of Online Patient Conversations. Elsevier  Value in Health  vol. 26, (7) 1057-1066.  

2022

Bessant C, Bridges Y, Chowdhury M, Tahsin A, Abdollahyan M, Smeraldi F and Byrom B (2022). PCR3 Assessing Concept Saturation and Sample Representativeness When Using Social Media Data to Inform Concept Elicitation Studies. Elsevier  Value in Health  vol. 25, (12)  
Waller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C and Alazawi W (2022). Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease. The Korean Association for the Study of the Liver  Clinical and Molecular Hepatology  vol. 29, (2) 417-432.  
Bridges Y, Chowdhury M, Tahsin A, Bessant C, Abdollahyan M, Smeraldi F and Byrom B (2022). POSB338 Identification of Meaningful Aspects of Physical Activity: Concept Elicitation By AI-Assisted Coding of Online Patient Conversations. Elsevier  Value in Health  vol. 25, (1)  

2021

Patel R, Smeraldi F, Abdollahyan M, Irving J and Bessant C (2021). Analysis of mental and physical disorders associated with COVID-19 in online health forums: a natural language processing study. BMJ  BMJ Open  vol. 11, (11)  

2020

Gomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C and Dalli J (2020). Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Springer Nature  Nature Communications  vol. 11, (1)  
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C (2020). Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. Nature Research (part of Springer Nature)  npj Breast Cancer  vol. 6, (1)  
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C (2020). Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. NPJ Breast Cancer  vol. 6, (1)  
Hijazi M, Smith R, Rajeeve V, Bessant C and Cutillas PR (2020). Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring. Nature Research  Nature Biotechnology   

2018

Saha S, Matthews DA and Bessant C (2018). High throughput discovery of protein variants using proteomics informed by transcriptomics. Oxford University Press (OUP)  Nucleic Acids Research  vol. 46, (10)  

2017

Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, Cutillas PR, Lockley M, Bessant C, Knight M and Balkwill FR (2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov   
SAHA S, Chatzimichali E, Matthews D and Bessant C (2017). PITDB: a database of translated genomic elements. Oxford University Press  Nucleic Acids Research   
Maringer K, Yousuf A, Heesom KJ, Fan J, Lee D, Fernandez-Sesma A, Bessant C, Matthews DA and Davidson AD (2017). Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti. BMC Genomics  vol. 18, (1) 101-101.  
Bessant C (2017). Acknowledgements. New Developments in Mass Spectrometry  vol. 2017-January, (5)  

2016

Saha S, Matthews D and Bessant C (2016). Chapter 16 Proteomics Informed by Transcriptomics. Proteome Informatics  Royal Society of Chemistry (RSC)   
Bessant C (2016). Chapter 1 Introduction to Proteome Informatics. Proteome Informatics  Royal Society of Chemistry (RSC)   
(2016). Proteome Informatics., Editors: Bessant C. The Royal Society of Chemistry   
Walton C, Montoya MPB, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C, Naylor SJ and Hunter JO (2016). Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational study. Nature Publishing Group: Open Access Hybrid Model Option B  European Journal of Clinical Nutrition  vol. 70, 1052-1056.  
Cauchi M, Weber CM, Bolt BJ, Spratt PB, Bessant C, Turner DC, Willis CM, Britton LE, Turner C and Morgan G (2016). Evaluation of gas chromatography mass spectrometry and pattern recognition for the identification of bladder cancer from urine headspace. Royal Society of Chemistry (RSC)  Analytical Methods  vol. 8, (20) 4037-4046.  
Mohareb F, Papadopoulou O, Panagou E, Nychas G-J and Bessant C (2016). Ensemble-based support vector machine classifiers as an efficient tool for quality assessment of beef fillets from electronic nose data. Royal Society of Chemistry (RSC)  Analytical Methods  vol. 8, (18) 3711-3721.  

2015

Chatzimichali EA and Bessant C (2015). Novel application of heuristic optimisation enables the creation and thorough evaluation of robust support vector machine ensembles for machine learning applications. Springer Nature  Metabolomics  vol. 12, (1)  
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR (2015). The mzqLibrary - An open source Java library supporting the HUPO-PSI quantitative proteomics standard. Proteomics  vol. 15, (18) 3152-3162.  
Fan J, Saha S, Barker G, Heesom KJ, Ghali F, Jones AR, Matthews DA and Bessant C (2015). Galaxy Integrated Omics: Web-based Standards-Compliant Workflows for Proteomics Informed by Transcriptomics*[S]. Elsevier  Molecular & Cellular Proteomics  vol. 14, (11) 3087-3093.  
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR (2015). The mzqLibrary – An open source Java library supporting the HUPO‐PSI quantitative proteomics standard. Wiley  Proteomics  vol. 15, (18) 3152-3162.  
Cauchi M, Fowler DP, Walton C, Turner C, Waring RH, Ramsden DB, Hunter JO, Teale P, Cole JA and Bessant C (2015). Comparison of GC-MS, HPLC-MS and SIFT-MS in conjunction with multivariate classification for the diagnosis of Crohn's disease in urine. Royal Society of Chemistry (RSC)  Analytical Methods  vol. 7, (19) 8379-8385.  

2014

Gonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR (2014). A tutorial for software development in quantitative proteomics using PSI standard formats. Biochim Biophys Acta  vol. 1844, (1 Pt A) 88-97.  
Bessant C, Oakley D and Shadforth I (2014). Building Bioinformatics Solutions. Oxford University Press   
Cauchi M, Fowler DP, Walton C, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH and others (2014). Application of gas chromatography mass spectrometry (GC–MS) in conjunction with multivariate classification for the diagnosis of gastrointestinal diseases. Springer US  Metabolomics  vol. 10, (6) 1113-1120.  
Sattlecker M, Stone N and Bessant C (2014). Current trends in machine-learning methods applied to spectroscopic cancer diagnosis. Elsevier/Science Direct  TrAC Trends in Analytical Chemistry  vol. 59, 17-25.  
Bessant C, Oakley D and Shadforth I (2014). Building Bioinformatics Solutions 2nd Edition. Oxford University Press   
Gonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR (2014). A tutorial for software development in quantitative proteomics using PSI standard formats. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS  vol. 1844, (1) 88-97.  

2013

Walton C, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C and Hunter JO (2013). Analysis of volatile organic compounds of bacterial origin in chronic gastrointestinal diseases. Inflamm Bowel Dis  vol. 19, (10) 2069-2078.  
Walzer M, Qi D, Mayer G, Uszkoreit J, Eisenacher M, Sachsenberg T, Gonzalez-Galarza FF, Fan J, Bessant C, Deutsch EW, Reisinger F, Vizcaíno JA, Medina-Aunon JA, Albar JP, Kohlbacher O and Jones AR (2013). The mzQuantML data standard for mass spectrometry-based quantitative studies in proteomics. Mol Cell Proteomics  vol. 12, (8) 2332-2340.  
Bessant C and Fan J (2013). Computational approaches to selected reaction monitoring assay design. Methods Mol Biol  vol. 1007, 219-235.  
Bessant C and Fan J (2013). Computational approaches to selected reaction monitoring assay design. Methods in Molecular Biology  vol. 1007, 219-235.  

2012

Evans VC, Barker G, Heesom KJ, Fan J, Bessant C and Matthews DA (2012). De novo derivation of proteomes from transcriptomes for transcript and protein identification. Nat Methods  vol. 9, (12) 1207-1211.  
Gonzalez-Galarza FF, Lawless C, Hubbard SJ, Fan J, Bessant C, Hermjakob H and Jones AR (2012). A critical appraisal of techniques, software packages, and standards for quantitative proteomic analysis. OMICS  vol. 16, (9) 431-442.  
Fan J, Mohareb F, Bond NJ, Lilley KS and Bessant C (2012). MRMaid 2.0: mining PRIDE for evidence-based SRM transitions. OMICS  vol. 16, (9) 483-488.  
Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH, Ramsden DB, Hunter JO, Cauchi M, Bessant C, Fowler DP, Walton C, Turner C and Cole JA (2012). Diversity and distribution of sulphate-reducing bacteria in human faeces from healthy subjects and patients with inflammatory bowel disease. FEMS Immunol Med Microbiol  vol. 65, (1) 55-68.  
Fan J, Mohareb F, Jones AME and Bessant C (2012). MRMaid: The SRM Assay Design Tool for Arabidopsis and Other Species. Front Plant Sci  vol. 3,  

2011

Thiollet S, Bessant C and Morgan SL (2011). Application of multiple response optimization design to quantum dot-encoded microsphere bioconjugates hybridization assay. Anal Biochem  vol. 414, (1) 23-30.  
Panagou EZ, Mohareb FR, Argyri AA, Bessant CM and Nychas G-JE (2011). A comparison of artificial neural networks and partial least squares modelling for the rapid detection of the microbial spoilage of beef fillets based on Fourier transform infrared spectral fingerprints. Food Microbiol  vol. 28, (4) 782-790.  
Weber CM, Cauchi M, Patel M, Bessant C, Turner C, Britton LE and Willis CM (2011). Evaluation of a gas sensor array and pattern recognition for the identification of bladder cancer from urine headspace. Analyst  vol. 136, (2) 359-364.  
Johnson PE, Baumgartner S, Aldick T, Bessant C, Giosafatto V, Heick J, Mamone G, O'Connor G, Poms R, Popping B, Reuter A, Ulberth F, Watson A, Monaci L and Mills ENC (2011). Current perspectives and recommendations for the development of mass spectrometry methods for the determination of allergens in foods. J AOAC Int  vol. 94, (4) 1026-1033.  
Cauchi M, Bianco L and Bessant C (2011). The quantification of pollutants in drinking water by use of artificial neural networks. Nat. Comput.  vol. 10, 77-90.  
Sattlecker M, Baker R, Stone N and Bessant C (2011). Support vector machine ensembles for breast cancer type prediction from mid-FTIR micro-calcification spectra. Elsevier  Chemometrics and Intelligent Laboratory Systems  vol. 107, 363-370.  
Sattlecker M, Stone N, Smith J and Bessant C (2011). Assessment of robustness and transferability of classification models built for cancer diagnostics using Raman spectroscopy. Wiley Online Library  Journal of Raman Spectroscopy  vol. 42, 897-903.  
Bessant C (2011). Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data Darius M. Dziuda John Wiley and Sons, 2010, p. 327 ISBN: 978-0-470-16373-3. WILEY-VCH Verlag  Proteomics  vol. 11, 3768-3768.  
Bessant C (2011). Experiences in Pattern Recognition for Machine Olfaction. American Institute of Physics   

2010

Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and Reither K (2010). Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis. J Clin Microbiol  vol. 48, (11) 4235-4238.  
Sattlecker M, Bessant C, Smith J and Stone N (2010). Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics. Analyst  vol. 135, (5) 895-901.  
Cham Mead JA, Bianco L and Bessant C (2010). Free computational resources for designing selected reaction monitoring transitions. Proteomics  vol. 10, (6) 1106-1126.  
Chem Mead JA, Bianco L and Bessant C (2010). Mining proteomic MS/MS data for MRM transitions. Methods Mol Biol  vol. 604, 187-199.  
Cham JA, Bianco L, Barton C and Bessant C (2010). MRMaid-DB: a repository of published SRM transitions. J Proteome Res  vol. 9, (1) 620-625.  
Tetsuya H (2010). Discerning data analysis methods to clarify agonistic/antagonistic actions on the ion flux assay of ligand-gated ionotropic glutamate receptor on engineered post-synapse model cells. Journal of Biosensors & Bioelectronics   
Tanoue C, Asakawa H, Cauchi M, Bessant C, Ikeno S and Haruyama T (2010). Tissular model/sensor seamless system for qualified analysis and its characterization. Elsevier  Biochemical Engineering Journal  vol. 52, 110-115.  
Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and others (2010). Electronic-nose technology in diagnosis of TB patients using sputum samples. Am Soc Microbiol  Journal of Clinical Microbiology   

2009

Spooner AD, Bessant C, Turner C, Knobloch H and Chambers M (2009). Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers. Analyst  vol. 134, (9) 1922-1927.  
Blanco L, Mead JA and Bessant C (2009). Comparison of novel decoy database designs for optimizing protein identification searches using ABRF sPRG2006 standard MS/MS data sets. J Proteome Res  vol. 8, (4) 1782-1791.  
Babrah J, McCarthy K, Lush RJ, Rye AD, Bessant C and Stone N (2009). Fourier transform infrared spectroscopic studies of T-cell lymphoma, B-cell lymphoid and myeloid leukaemia cell lines. Analyst  vol. 134, (4) 763-768.  
Mead JA, Bianco L, Ottone V, Barton C, Kay RG, Lilley KS, Bond NJ and Bessant C (2009). MRMaid, the web-based tool for designing multiple reaction monitoring (MRM) transitions. Mol Cell Proteomics  vol. 8, (4) 696-705.  
Moczko E, Meglinski IV, Bessant C and Piletsky SA (2009). Dyes assay for measuring physicochemical parameters. Anal Chem  vol. 81, (6) 2311-2316.  
Mead JA, Bianco L and Bessant C (2009). Recent developments in public proteomic MS repositories and pipelines. Proteomics  vol. 9, (4) 861-881.  
Thanaraj T, Terry LA and Bessant C (2009). Chemometric profiling of pre-climacteric Sri Lankan mango fruit (< i> Mangifera indica L.). Elsevier  Food Chemistry  vol. 112, 786-794.  
Tottey S, Robinson N, Waldron K, Firbank S and Bessant C (2009). Protein folding location determines binding of manganese versus copper. Pergamon  Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology  vol. 153, S159-S159.  

2008

Robinson N, Waldron K, Tottey S and Bessant C (2008). Metalloprotein metal pools: identification and quantification by coupling native and non-native separations through principal component analysis. Springer Nature  Protocol Exchange   
Tottey S, Waldron KJ, Firbank SJ, Reale B, Bessant C, Sato K, Cheek TR, Gray J, Banfield MJ, Dennison C and Robinson NJ (2008). Protein-folding location can regulate manganese-binding versus copper- or zinc-binding. Nature  vol. 455, (7216) 1138-1142.  
Stott W, Ryan A, Jacobs IJ, Menon U, Bessant C and Jones C (2008). OSPACS: Ultrasound image management system. Source Code Biol Med  vol. 3,  
Cauchi M, Bessant C and Setford S (2008). Simultaneous Quantitative Determination of Cadmium, Lead, and Copper on Carbon-Ink Screen-Printed Electrodes by Differential Pulse Anodic Stripping Voltammetry and Partial Least Squares Regression. Wiley Online Library  Electroanalysis  vol. 20, 2571-2577.  
Mead J, Bianco L and Bessant C (2008). Using Bioinformatics to Increase Speed and Reduce Uncertainty in Protein Biomarker Discovery. Cranfield Multi-Strand Conference: Creating Wealth Through Research and Innovation  vol. 6, 118-118.  

2007

Mead JA, Shadforth IP and Bessant C (2007). Public proteomic MS repositories and pipelines: available tools and biological applications. Proteomics  vol. 7, (16) 2769-2786.  
Goodacre R, Broadhurst D, Smilde AK, Kristal BS, Baker JD, Beger R, Bessant C, Connor S, Capuani G, Craig A and others (2007). Proposed minimum reporting standards for data analysis in metabolomics. Springer US  Metabolomics  vol. 3, 231-241.  
Bessant C (2007). Microarray Analysis Software and its Applications. John Wiley & Sons, Ltd  Handbook of Biosensors and Biochips   
Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N (2007). FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines [6628-28]. International Society for Optical Engineering; 1999  PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING  vol. 6628, 6628-6628.  
Kumuthini J, Bessant C, Wilson P and Crowther D (2007). Gene regulatory network of human adipocyte differentiation. BioMed Central Ltd  BMC Systems Biology  vol. 1, P57-P57.  
Kumuthini J, Jouffe L and Bessant C (2007). Session 1-Microarray and Systems Biology I (Networks)-A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data. Lecture Notes in Computer Science  vol. 4414, 28-28.  

2006

Shadforth I and Bessant C (2006). Genome annotating proteomics pipelines: available tools. Expert Rev Proteomics  vol. 3, (6) 621-629.  
Shadforth I, Xu W, Crowther D and Bessant C (2006). GAPP: a fully automated software for the confident identification of human peptides from tandem mass spectra. J Proteome Res  vol. 5, (10) 2849-2852.  
Ernst W, Trummer E, Mead J, Bessant C, Strelec H, Katinger H and Hesse F (2006). Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells. Biotechnol J  vol. 1, (6) 639-650.  
Fend R, Kolk AHJ, Bessant C, Buijtels P, Klatser PR and Woodman AC (2006). Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum. J Clin Microbiol  vol. 44, (6) 2039-2045.  
Dunkley TPJ, Hester S, Shadforth IP, Runions J, Weimar T, Hanton SL, Griffin JL, Bessant C, Brandizzi F, Hawes C, Watson RB, Dupree P and Lilley KS (2006). Mapping the Arabidopsis organelle proteome. Proc Natl Acad Sci U S A  vol. 103, (17) 6518-6523.  
Saini S, Bessant C, Lee-davey J and Malecha MM (2006). VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS. 
Sadowski PG, Dunkley TPJ, Shadforth IP, Dupree P, Bessant C, Griffin JL and Lilley KS (2006). Quantitative proteomic approach to study subcellular localization of membrane proteins. Nat Protoc  vol. 1, (4) 1778-1789.  
Lilley KS, Hawes C, Hanton SL, Dunkley TPJ, Runions J, Hester S, Weimar T, Shadforth IP, Bessant C, Dupree P and others (2006). Mapping the Arabidopsis organelle proteome. Editor no identificado  Proceedings of the National Academy of Sciences of the United States of America  6518-6523.  

2005

Shadforth I, Crowther D and Bessant C (2005). Protein and peptide identification algorithms using MS for use in high-throughput, automated pipelines. Proteomics  vol. 5, (16) 4082-4095.  
Shadforth IP, Dunkley TPJ, Lilley KS and Bessant C (2005). i-Tracker: for quantitative proteomics using iTRAQ. BMC Genomics  vol. 6,  
Shadforth I, Todd K, Crowther D and Bessant C (2005). Determination of partial amino acid composition from tandem mass spectra for use in peptide identification strategies. Proteomics  vol. 5, (7) 1787-1796.  
SAINI S, BESSANT C, LEE-DAVEY J, MALECHA M and others (2005). VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS. 
Shadforth I, Dunkley T, Lilley K, Crowther D and Bessant C (2005). Confident protein identification using the average peptide score method coupled with search-specific, ab initio thresholds. Rapid Commun Mass Spectrom  vol. 19, (22) 3363-3368.  
Mead JA, Bianco L and Bessant C (2005). the focus of attention in financial reporting. Abacus   

2004

Fend R, Bessant C, Williams AJ and Woodman AC (2004). Monitoring haemodialysis using electronic nose and chemometrics. Biosens Bioelectron  vol. 19, (12) 1581-1590.  
Saini S, Bessant C, Lee-Davey J and Malecha MM (2004). Voltammetric detection of metabolites in physiological fluids. Google Patents   
Richards E, Bessant C and Saini S (2004). Simultaneous quantification of analytes in quaternary mixtures using dual pulse staircase voltammetry and genetically optimised neural networks. Analyst  vol. 129, (4) 355-358.  
Saini S, Bessant C, Liedtke C and Leiferkus J (2004). DIAGNOSIS BY SENSING VOLATILE COMPONENTS. 

2003

Malecha M, Bessant C and Saini S (2003). Identification of oil contaminants on polymer coated beverage cans using fluorescence spectroscopy. Appl Spectrosc  vol. 57, (8) 1042-1048.  
Richards E, Bessant C and Saini S (2003). A liquid handling system for the automated acquisition of data for training, validating and testing calibration models. Elsevier  Sensors and Actuators B: Chemical  vol. 88, 149-154.  
Bessant C and Richards E (2003). Neural networks for the calibration of voltammetric data. Elsevier  Nature-inspired methods in chemometrics: genetic algorithms and artificial neural networks: genetic algorithms and artificial ne  vol. 23, 257-257.  

2002

SAINI S, BESSANT C, LIEDTKE C, LEIFERKUS J and others (2002). DIAGNOSIS BY SENSING VOLATILE COMPONENTS. 
Malecha M, Bessant C and Saini S (2002). Principal components analysis for the visualisation of multidimensional chemical data acquired by scanning Raman microspectroscopy. Analyst  vol. 127, (9) 1261-1266.  
Saini S, Bessant C, Liedtke C and Leiferkus J (2002). Diagnosis by sensing volatile components. Google Patents   
Richards E, Bessant C and Saini S (2002). Multivariate data analysis in electroanalytical chemistry. Wiley Online Library  Electroanalysis  vol. 14, 1533-1542.  
Richards E, Bessant C and Saini S (2002). Optimisation of a neural network model for calibration of voltammetric data. Elsevier  Chemometrics and intelligent laboratory systems  vol. 61, 35-49.  
Malecha M, Bessant C, Perry D and Saini S (2002). Identification of oil contaminants on polymer coated beverage cans using Raman spectroscopy. Royal Society of Chemistry  Analyst  vol. 127, 297-303.  

2001

Saini S, Barr H and Bessant C (2001). Sniffing out disease using the artificial nose. Biologist (London)  vol. 48, (5) 229-233.  
Bessant C, Ritchie L, Saini S, Pahlavanpour B and Wilson G (2001). Chemometric evaluation of synchronous scan fluorescence spectroscopy for the determination of regulatory conformance and usage history of insulation oils. Society for Applied Spectroscopy  Applied spectroscopy  vol. 55, 840-846.  

2000

Ritchie LJ, Ferguson CP, Bessant C and Saini S (2000). A ten channel fibre-optic device for distributed sensing of underground hydrocarbon leakage. J Environ Monit  vol. 2, (6) 670-673.  
SAINI S and BESSANT C (2000). ANALYSIS OF MIXTURES. 
Bessant C and Saini S (2000). A chemometric analysis of dual pulse staircase voltammograms obtained in mixtures of ethanol, fructose and glucose. Elsevier  Journal of electroanalytical chemistry  vol. 489, 76-83.  

1999

Bessant C and Saini S (1999). Simultaneous determination of ethanol, fructose, and glucose at an unmodified platinum electrode using artificial neural networks. ACS Publications  Analytical Chemistry  vol. 71, 2806-2813.  
Brereton R and others (1999). Integrated processing of triply coupled diode array liquid chromatography electrospray mass spectrometric signals by chemometric methods. Royal Society of Chemistry  Analyst  vol. 124, 1733-1744.  

1997

Bessant C and Saini S (1997). An object oriented approach to electroanalytical technique implementation. Wiley Online Library  Electroanalysis  vol. 9, 926-931.  

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconAI driven Omics Data Integration and Transfer Learning for Target and Biomarker Identification
Conrad Bessant
£127,935 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2024 - 30-09-2028)
bullet iconBBSRC AIDD CTP CASE Award: Syed Zayyan Masud
Conrad Bessant
£21,600 Nxera Pharma UK Ltd (01-10-2024 - 30-09-2028)
bullet iconMechanisms underlying preterm birth in women with HIV in rural Zimbabwe
Andrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 MRC Medical Research Council (01-05-2024 - 30-04-2027)
bullet iconMartina Occhetta CTP Studentship - Exscientia Funded
Conrad Bessant and Emma Tjong
£8,600 EXSCIENTIA LIMITED (01-10-2023 - 30-09-2027)
bullet iconTG: Target identification from multiomics data using systems biology and machine learning approaches
Conrad Bessant
£125,917 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2023 - 30-09-2027)
bullet iconCTP Training Grant: Lewis Palmer
Conrad Bessant
£123,829 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2022 - 12-11-2026)
bullet iconBBSRC AIDD CTP CASE Award: Lewis Palmer: “Prioritising Drug Targets in non-canonical pathways from multi-omic data
Conrad Bessant
£10,400 Merck (26-09-2022 - 25-09-2026)
bullet iconSurvey and BIOinformatic review of fluid-tissue proteomics: novel biomarkers for ALS
Andrea Malaspina and Conrad Bessant
£188,946 Barts and the London Charity (01-09-2020 - 31-08-2025)


bullet iconIdentifying regulatory nodes and vulnerablities of molecular networks using graph theory and machine learning analysis of proteomics data
Pedro Rodriguez Cutillas and Conrad Bessant
£45,554 Alan Turing Institute, The (01-03-2020 - 31-01-2021)
bullet iconAlan Turing Institute Enrichment Placement Scheme - George Elder
Conrad Bessant
£1,746 Alan Turing Institute, The (01-01-2020 - 30-06-2020)
bullet iconAutomatic Learning in Cancer Research using Artificial Intelligence
Trevor Graham and Conrad Bessant
£178,177 Alan Turing Institute, The (01-10-2018 - 31-03-2022)
bullet iconBid for MRC Industrial Strategy PhD Studentship 2018
Conrad Bessant
£93,462 MRC Medical Research Council (01-10-2018 - 31-03-2022)