Dr Christopher Chapman

Christopher Chapman

Lecturer in Bioengineering

School of Engineering and Materials Science
Queen Mary University of London

Research

bioelectronics, biosensing, medical devices, conducting polymers

Cancer Models, Neuronal Models

Interests

Interested in pairing bioelectronic sensors to in vitro models to achieve real-time readout from the in vitro model system. Investigating coupling multiple modalities of recordings such as impedance, pH, and biomarker sensing to the in vitro systems.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

P07.15.A ELECTROACTIVE DRUG DELIVERY DEVICE FOR TARGETED INTRATUMORAL THERAPY
KILLILEA J, Lee A, Miceli G, Cuttaz E, Van Der Auweraert I, Kontrimaite U, Landeira-Suquia L, De Ferm R et al.
Neuro-Oncology, Oxford University Press (Oup) vol. 27 (Supplement_3), iii80-iii80.  
03-10-2025
“Spin‐Rinse and Repeat”: Facile Processing to Improve Cytocompatibility of Poly(3,4‐Ethyelenedioxythiophene): Polystyrene Sulfonate Composites for Bioelectronics
Killilea J, Lee A, Cuttaz EA, Miceli GC, Suquia LL, Goding JA, Chapman CAR, Green RA
Advanced Nanobiomed Research, Wiley vol. 5 (5) 
13-04-2025

2024

3D printed electro-responsive system with programmable drug release
Alkahtani ME, Sun S, Chapman CAR, Gaisford S, Orlu M, Elbadawi M, Basit AW
Materials Today Advances, Elsevier vol. 23 
01-08-2024
Polymer Bioelectronics: A Solution for Both Stimulating and Recording Electrodes
Cuttaz EA, Bailey ZK, Chapman CAR, Goding JA, Green RA
Advanced Healthcare Materials, Wiley vol. 13 (24) 
31-05-2024
Surgical identification of brain tumour margins through impedance monitoring and electrocorticography and the potential for their combined use: A systematic review
Georgiannakis A, Chapman CAR, Paraskevopoulos D
Neurosurgical Review, Springer Nature vol. 47 (1) 
01-01-2024

2023

Controlled electroactive release from solid-state conductive elastomer electrodes
Chapman CAR, Fernandez-Patel S, Jahan N, Cuttaz EA, Novikov A, Goding JA, Green RA
Materials Today Bio, Elsevier vol. 23 
28-11-2023
Electroactive Polymers for On‐Demand Drug Release
Alkahtani ME, Elbadawi M, Chapman CAR, Green RA, Gaisford S, Orlu M, Basit AW
Advanced Healthcare Materials, Wiley vol. 13 (3) 
12-11-2023
Surface electromyography using dry polymeric electrodes
Steenbergen N, Busha I, Morgan A, Mattathil C, Pinto AL, Spyridakos F, Sokolovskiy I, Tahirbegi B et al.
Apl Bioengineering, Aip Publishing vol. 7 (3) 
01-09-2023
A Pilot In Vivo Study of Flexible Fully Polymeric Nerve Cuff Electrodes*
Cuttaz EA, Syed O, Chapman CAR, Goding JA, Bailey ZK, Portillo-Lara R, Green RA
2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
01-07-2023

2022

Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology
Rapeaux A, Syed O, Cuttaz E, Chapman CAR, Green RA, Constandinou TG
Journal of Visualized Experiments, Myjove (185) 
12-07-2022
Preparation of Rat Sciatic Nerve for Ex Vivo Neurophysiology
Rapeaux A, Syed O, Cuttaz E, Chapman CAR, Green RA, Constandinou TG
Journal of Visualized Experiments, Myjove (185) 
12-07-2022

2021

Flexible Networks of Patterned Conducting Polymer Nanowires for Fully Polymeric Bioelectronics
Chapman CAR, Cuttaz EA, Tahirbegi B, Novikov A, Petkos K, Koutsoftidis S, Drakakis EM, Goding JA et al.
Advanced Nanobiomed Research, Wiley vol. 2 (3) 
04-12-2021
Flexible Nanowire Conductive Elastomers for Applications in Fully Polymeric Bioelectronic Devices *
Cuttaz EA, Chapman CAR, Goding JA, Vallejo-Giraldo C, Syed O, Green RA
2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
01-11-2021
Mind the gap: State-of-the-art technologies and applications for EEG-based brain–computer interfaces
Portillo-Lara R, Tahirbegi B, Chapman CAR, Goding JA, Green RA
Apl Bioengineering, Aip Publishing vol. 5 (3) 
20-07-2021
Stretchable, Fully Polymeric Electrode Arrays for Peripheral Nerve Stimulation
Cuttaz EA, Chapman CAR, Syed O, Goding JA, Green RA
Advanced Science, Wiley vol. 8 (8) 
05-02-2021
Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation
Aristovich K, Donega M, Fjordbakk C, Tarotin I, Chapman CAR, Viscasillas J, Stathopoulou T-R, Crawford A et al.
Journal of Neuroscience Methods, Elsevier vol. 352 
28-01-2021

2020

Stretchable bioelectronics: Mitigating the challenges of the percolation threshold in conductive elastomers
Novikov A, Goding J, Chapman C, Cuttaz E, Green RA
Apl Materials, Aip Publishing vol. 8 (10) 
01-10-2020
Actively controlled local drug delivery using conductive polymer-based devices
Chapman CAR, Cuttaz EA, Goding JA, Green RA
Applied Physics Letters, Aip Publishing vol. 116 (1) 
03-01-2020
3D Cell Culture Systems for the Development of Neural Interfaces
Syed O, Chapman C, Vallejo-Giraldo C, Genta M, Goding J, Kanelos E, Green R
In Neural Interface Engineering, Springer Nature 201-236.  
01-01-2020

2019

Optimisation of bioimpedance measurements of neuronal activity with an ex vivo preparation of Cancer pagurus peripheral nerves
Chapman CAR, Smith TM, Kelly M, Avery J, Rouanet T, Aristovich K, Chew DJ, Holder DS
Journal of Neuroscience Methods, Elsevier vol. 327 
13-08-2019
Model-based geometrical optimisation and in vivo validation of a spatially selective multielectrode cuff array for vagus nerve neuromodulation
Aristovich K, Donega M, Fjordbakk C, Tarotin I, Chapman C, Viscasillas J, Stathopoulou T-R, Crawford A et al.
In Arxiv 
29-03-2019
Optimal frequency range for electrical impedance tomography of neural activity in peripheral nerve
Hope J, Aristovich K, Chapman C, Vanholsbeeck F, McDaid A
2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)
23-03-2019
Extracting impedance changes from a frequency multiplexed signal during neural activity in sciatic nerve of rat: preliminary study in vitro
Hope J, Aristovich K, Chapman CAR, Volschenk A, Vanholsbeeck F, McDaid A
Physiological Measurement, Iop Publishing vol. 40 (3) 
01-03-2019
Extracting impedance changes from a frequency multiplexed signal during neural activity in sciatic nerve of rat: preliminary study in-vitro
Hope J, Aristovich K, Chapman CAR, Volschenk A, Vanholsbeeck F, McDaid A
In Arxiv 
07-01-2019
Mechanically Robust Soft Bioelectronics: Towards Conductive Elastomers with a Low Percolation Threshold
Novikov A, Goding J, Chapman C, Cuttaz E, Green R
In Ssrn Electronic Journal 
01-01-2019

2018

Electrode fabrication and interface optimization for imaging of evoked peripheral nervous system activity with electrical impedance tomography (EIT)
Chapman CAR, Aristovich K, Donega M, Fjordbakk CT, Stathopoulou T-R, Viscasillas J, Avery J, Perkins JD et al.
Journal of Neural Engineering, Iop Publishing vol. 16 (1) 
16-11-2018

2017

Multifunctional Neural Interfaces for Closed‐Loop Control of Neural Activity
Chapman CAR, Goshi N, Seker E
Advanced Functional Materials, Wiley vol. 28 (12) 
28-08-2017
Nanostructure Introduces Artifacts in Quantitative Immunofluorescence by Influencing Fluorophore Intensity
Chapman CAR, Zhu X, Chen H, Yanik AA, Lein PJ, Seker E
Scientific Reports, Springer Nature vol. 7 (1) 
27-03-2017
Neural Interfaces: Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance (Adv. Funct. Mater. 3/2017)
Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ, Seker E
Advanced Functional Materials, Wiley vol. 27 (3) 
01-01-2017

2016

Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance
Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ, Seker E
Advanced Functional Materials, Wiley vol. 27 (3) 
12-12-2016
Mechanisms of Reduced Astrocyte Surface Coverage in Cortical Neuron-Glia Co-cultures on Nanoporous Gold Surfaces
Chapman CAR, Chen H, Stamou M, Lein PJ, Seker E
Cellular and Molecular Bioengineering, Springer Nature vol. 9 (3), 433-442.  
31-05-2016
Utilizing dynamic laser speckle to probe nanoscale morphology evolution in nanoporous gold thin films
Chapman CAR, Ly S, Wang L, Seker E, Matthews MJ
Optics Express, Optica Publishing Group vol. 24 (5), 5323-5333.  
02-03-2016
Engineering on-chip nanoporous gold material libraries via precision photothermal treatment
Chapman CAR, Wang L, Biener J, Seker E, Biener MM, Matthews MJ
Nanoscale, Royal Society of Chemistry (Rsc) vol. 8 (2), 785-795.  
01-01-2016
Substrate topography guides pore morphology evolution in nanoporous gold thin films
Chapman CAR, Daggumati P, Gott SC, Rao MP, Seker E
Scripta Materialia, Elsevier vol. 110, 33-36.  
01-01-2016

2015

Nanoporous Gold as a Neural Interface Coating: Effects of Topography, Surface Chemistry, and Feature Size
Chapman CAR, Chen H, Stamou M, Biener J, Biener MM, Lein PJ, Seker E
Acs Applied Materials & Interfaces, American Chemical Society (Acs) vol. 7 (13), 7093-7100.  
02-03-2015

2013

Microfabrication of nanoporous gold patterns for cell-material interaction studies.
Daggumati P, Kurtulus O, Chapman CAR, Dimlioglu D, Seker E
Journal of Visualized Experiments, Myjove (77) 
15-07-2013
Microfabrication of Nanoporous Gold Patterns for Cell-material Interaction Studies
Daggumati P, Kurtulus O, Chapman CAR, Dimlioglu D, Seker E
Journal of Visualized Experiments, Myjove (77) 
15-07-2013

Simple surface treatment of conjugated polymers for enhanced cell adhesion using UV-Ozone
Westwood MM, Gilhooly-Finn PA, Trueman RP, Mumtaz A, Gregory H, Daoud JPA, Dey A, Palgrave R et al.
In Chemrxiv 
Neuromodulation of a peripheral nerve using fully polymeric cuff electrodes: Understanding predictability of selective stimulation
Bailey Z, Nairac Z, Cuttaz EA, M’Rad IB, Chapman CAR, Rapeaux A, Goding J, Roche A et al.
In Biorxiv 

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconOligodendronics: Engineering biology for scalable neural interfaces
Christopher Chapman
£403,666 ARIA Advanced Research and Invention Agency 
Grant Summary

01-07-2025 - 31-12-2026
bullet iconDevelopment of multimodal tumour margin detection paradigm for use in neurosurgical oncology
Christopher Chapman
£74,990 Barts and the London Charity 
Grant Summary

31-03-2025 - 31-03-2026


solid heart iconCustomizable conducting elastomers for bioelectronics sensors
Christopher Chapman
£20,000 Royal Society 
Grant Summary

01-10-2024 - 30-09-2025