Dr Christoph Engl
Senior Lecturer in Microbiology
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
Bacteria, Cell Biology, Molecular Biology, Single cell imaging and spectroscopy
Interests
My lab is interested in understanding how bacteria adapt to and shape their environment. We study the biology and behaviour of bacterial cells from single molecules and single cells to population level.Publications
2022
Kotta-Loizou I, Giuliano MG, Jovanovic M, Schaefer J, Ye F, Zhang N, Irakleidi DA, Liu X, Zhang X, Buck M and Engl C (2022). The RNA repair proteins RtcAB regulate transcription activator RtcR via its CRISPR-associated Rossmann fold domain. Cell Press iScience 105425-105425.
Bashir T, Brackston RD, Waite C, Kotta-Loizou I, Carey MR, Engl C, Buck M and Schumacher J (2022). Molecular Origins of Transcriptional Heterogeneity in Diazotrophic Klebsiella oxytoca. American Society for Microbiology mSystems e0059622-e0059622.
2021
Giuliano MG and Engl C (2021). The Lifecycle of Ribosomal RNA in Bacteria. RNA Damage and Repair Springer Nature
2020
Mahbub M, Hemm L, Yang Y, Kaur R, Carmen H, Engl C, Huokko T, Riediger M, Watanabe S, Liu L-N, Wilde A, Hess WR and Mullineaux CW (2020). mRNA localization, reaction centre biogenesis and thylakoid membrane targeting in cyanobacteria. Springer Nature Nature Plants vol. 6, (9) 1179-1191.
Engl C, Jovanovic G, Brackston RD, Kotta-Loizou I and Buck M (2020). The route to transcription initiation determines the mode of transcriptional bursting in E. coli. Nature Research (part of Springer Nature) Nature Communications vol. 11,
2019
Kotta-Loizou I, Jovanovic M, Schaefer J, Engl C, Zhang N and Buck M (2019). A CRISPR-associated Rossmann fold (CARF) domain regulates transcription of an RNA repair system in Escherichia coli. Microbiology Society Access Microbiology vol. 1, (1A)
2018
Engl C (2018). Noise in bacterial gene expression. Portland Press Biochemical Society Transactions vol. 47, (1) 209-217.
Finch EA, Caruso T and ENGL CM (2018). Effects of Paenibacillus polymyxa inoculation on below-ground nematode communities and plant growth. Elsevier Soil Biology and Biochemistry vol. 121, 1-7.
2017
George TS, Giles CD, Menezes-Blackburn D, Condron LM, Gama-Rodrigues AC, Jaisi D, Lang F, Neal AL, Stutter MI, Almeida DS, Bol R, Cabugao KG, Celi L, Cotner JB, Feng G, Goll DS, Hallama M, Krueger J, Plassard C, Rosling A, Darch T, Fraser T, Giesler R, Richardson AE, Tamburini F, Shand CA, Lumsdon DG, Zhang H, Blackwell MSA and Wearing C (2017). Correction to: Organic phosphorus in the terrestrial environment: a perspective on the state of the art and future priorities (Plant and Soil, (2018), 427, 1-2, (191-208), 10.1007/s11104-017-3391-x). Plant and Soil vol. 427, (1-2) 209-211.
George TS, Giles CD, Menezes-Blackburn D, Condron LM, Gama-Rodrigues AC, Jaisi D, Lang F, Neal AL, Stutter MI, Almeida DS, Bol R, Cabugao KG, Celi L, Cotner JB, Feng G, Goll DS, Hallama M, Krueger J, Plassard C, Rosling A, Darch T, Fraser T, Giesler R, Richardson AE, Tamburini F, Shand CA, Lumsdon DG, Zhang H, Blackwell MSA and Wearing C (2017). Organic phosphorus in the terrestrial environment: a perspective on the state of the art and future priorities. Plant and Soil
Sihto H-M, Stephan R, Engl C, Chen J and Johler S (2017). Effect of food-related stress conditions and loss of agr and sigB on seb promoter activity in S. aureus. Food Microbiology vol. 65, 205-212.
2016
Engl C, Schaefer J, Kotta-Loizou I and Buck M (2016). Cellular and molecular phenotypes depending upon the RNA repair system RtcAB of Escherichia coli. Nucleic Acids Research gkw628-gkw628.
2015
Schaefer J, Engl C, Zhang N, Lawton E and Buck M (2015). Genome wide interactions of wild-type and activator bypass forms of σ54. Nucleic Acids Research vol. 43, (15) 7280-7291.
ENGL CHRISTOPH (2015). In Vitro and In Vivo Methodologies for Studying the Sigma 54-Dependent Transcription. Bacterial Transcriptional Control
2014
Engl C, Waite CJ, McKenna JF, Bennett MH, Hamann T and Buck M (2014). Chp8, a Diguanylate Cyclase from Pseudomonas syringae pv. Tomato DC3000, Suppresses the Pathogen-Associated Molecular Pattern Flagellin, Increases Extracellular Polysaccharides, and Promotes Plant Immune Evasion. mBio vol. 5, (3) e01168-14-e01168-14.
2013
Mehta P, Jovanovic G, Lenn T, Bruckbauer A, Engl C, Ying L and Buck M (2013). Dynamics and stoichiometry of a regulated enhancer-binding protein in live Escherichia coli cells. Springer Nature Nature Communications vol. 4, (1)
2012
Johler S, Moser M, Engl C, Tasara T, Corti S, Chen J and Stephan R (2012). A Coagulase- and α-Glucosidase-Negative Variant of Staphylococcus aureus: a Challenge for Routine Microbiological Diagnostics. American Society for Microbiology Journal of Clinical Microbiology vol. 50, (5) 1827-1828.
2011
Engl C, Beek AT, Bekker M, de Mattos JT, Jovanovic G and Buck M (2011). Dissipation of Proton Motive Force is not Sufficient to Induce the Phage Shock Protein Response in Escherichia coli. Springer Nature Current Microbiology vol. 62, (5) 1374-1385.
2010
Huvet M, Toni T, Sheng X, Thorne T, Jovanovic G, Engl C, Buck M, Pinney JW and Stumpf MPH (2010). The Evolution of the Phage Shock Protein Response System: Interplay between Protein Function, Genomic Organization, and System Function. Oxford University Press (OUP) Molecular Biology and Evolution vol. 28, (3) 1141-1155.
Lenn T, Gkekas CN, Bernard L, Engl C, Jovanovic G, Buck M and Ying L (2010). Measuring the stoichiometry of functional PspA complexes in living bacterial cells by single molecule photobleaching. Royal Society of Chemistry (RSC) Chem. Commun. vol. 47, (1) 400-402.
Joly N, Engl C, Jovanovic G, Huvet M, Toni T, Sheng X, Stumpf MPH and Buck M (2010). Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology. Oxford University Press (OUP) FEMS Microbiology Reviews vol. 34, (5) 797-827.
Jovanovic G, Engl C, Mayhew AJ, Burrows PC and Buck M (2010). Properties of the phage-shock-protein (Psp) regulatory complex that govern signal transduction and induction of the Psp response in Escherichia coli. Microbiology Society Microbiology vol. 156, (10) 2920-2932.
2009
Joly N, Burrows PC, Engl C, Jovanovic G and Buck M (2009). A Lower-Order Oligomer Form of Phage Shock Protein A (PspA) Stably Associates with the Hexameric AAA+ Transcription Activator Protein PspF for Negative Regulation. Elsevier Journal of Molecular Biology vol. 394, (4) 764-775.
Jovanovic G, Engl C and Buck M (2009). Physical, functional and conditional interactions between ArcAB and phage shock proteins upon secretin‐induced stress in Escherichia coli. Wiley Molecular Microbiology vol. 74, (1) 16-28.
Huvet M, Toni T, Tan H, Jovanovic G, Engl C, Buck M and Stumpf MPH (2009). Model-based evolutionary analysis: the natural history of phage-shock stress response. Portland Press Biochemical Society Transactions vol. 37, (4) 762-767.
Engl C, Jovanovic G, Lloyd LJ, Murray H, Spitaler M, Ying L, Errington J and Buck M (2009). In vivo localizations of membrane stress controllers PspA and PspG inEscherichia coli. Wiley Molecular Microbiology vol. 73, (3) 382-396.