Dr Caroline Roney

Caroline Roney

Reader in Computational Medicine

School of Engineering & Materials Science
Queen Mary University of London
www.sems.qmul.ac.uk/staff/c.roney

Research

Computational Medicine, Cardiac Arrhythmia, Biophysical Modelling, Machine learning, Signal Processing, Image Processing

Cardiovascular Models

Interests

Interested in the integration of AI and machine learning techniques with in vitro organ-chip models with a particular focus on cardiovascular applications.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2025

Recovering intrinsic conduction velocity and action potential duration from electroanatomic mapping data using curvature

Medical Image Analysis, Elsevier vol. 107 (Pt A) 
16-09-2025
Uncertainty should be the rule, not the exception: Integrating fibre orientation variability in cardiac electrophysiology modelling

The Journal of Physiology, Wiley 
04-09-2025
Advancing personalised treatment selection for atrial fibrillation: An in silico approach

Journal of Pharmacological and Toxicological Methods, Elsevier vol. 135, 107854-107854.  
01-09-2025
Ganglionated plexi ablation impact on atrial fibrillation mechanisms and outcomes in patients with low scar burden
Honarbakhsh S, Roney C, Al-Aidarous S, Horrach CV, Lambiase PD, Hunter RJ
Ep Europace, Oxford University Press (Oup) vol. 27 (9) 
25-08-2025
Three-dimensional left atrial strain from retrospective gated computed tomography: Comparison with speckle-tracking echocardiography in patients with aortic stenosis
Sillett C, Androshchuk V, Long E, Baptiste TMG, Strocchi M, Lemus JAS, Lee AW, Roney CH et al.
Journal of Cardiovascular Computed Tomography, Elsevier 
01-08-2025
High Density Evaluation of the Arrhythmogenic Substrate in Atrial Fibrillation (HEAT-AF)
Valli H, Ehnesh M, Coveney S, Jones DG, Chen Z, Hussain W, Markides V, Nanthakumar K et al.
Heart Rhythm O2, Elsevier 
01-07-2025
Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications
Horrach CV, Bevis L, Nwanna C, Zolotarev AM, Ehnesh M, Misghina SB, Al‐Aidarous S, Honarbakhsh S et al.
The Journal of Physiology, Wiley 
28-05-2025
Is regional atrial strain a useful surrogate of regional atrial fibrosis in atrial cardiomyopathy?
Lee AWC, Sillett C, Solis-Lemus JA, Iglesias CK, Hopman LHGA, Hua A, Wheen P, Qayyum A et al.
European Heart Journal - Imaging Methods and Practice, Oxford University Press (Oup) vol. 3 (2) 
28-05-2025
Rhythm control benefits left ventricular function compared with rate control in patients with atrial fibrillation: A computational study
Barrows RK, Augustin CM, Gsell MAF, Roney CH, Lemus JAS, Xu H, Young AA, Rajani R et al.
Heart Rhythm O2, Elsevier vol. 6 (7), 1011-1019.  
09-05-2025
Performance of atrial conduction velocity algorithms with error-prone clinical measurements for the identification of atrial fibrosis
Gharaviri A, Vigneswaran V, Vickneson K, Roney C, Corrado C, Coveney S, Maciunas K, Bodagh N et al.
Computers in Biology and Medicine, Elsevier vol. 191 
17-04-2025
Synthetic fibrosis distributions for data augmentation in predicting atrial fibrillation ablation outcomes: an in silico study
Zolotarev AM, Johnson K, Mohammad Y, Alwazzan O, Slabaugh G, Roney CH
Frontiers in Cardiovascular Medicine, Frontiers vol. 12 
11-04-2025
PO-FP-077 INVESTIGATING BORDER ZONE EFFECTS ON VENTRICULAR LOCAL ACTIVATION TIME USING IMAGING AND ELECTRICAL DATA DIGITAL TWINS
Cheng F, Tonko J, Rauseo E, Misghina SB, Barrera C, Vigmond EJ, Slabaugh G, Aung N et al.
Heart Rhythm, Elsevier vol. 22 (4), s113-s113.  
01-04-2025
PO-05-069 IN-SILICO TRIAL OF AMIODARONE IN ALTERING THE ARRHYTHMOGENICITY OF ATRIAL FIBRILLATION PATIENTS
Lee AW, Corrado C, Strocchi M, Hopman LH, Roney CH, Götte M, Plank G, Niederer SA
Heart Rhythm, Elsevier vol. 22 (4), s593-s594.  
01-04-2025
PO-05-045 PATIENT-SPECIFIC BIATRIAL MODELS RECREATED FROM CLINICAL DATA ENABLE PERSONALIZED AF THERAPY
Horrach CV, Coveney S, Jaffery OA, Ehnesh M, Niederer SA, Honarbakhsh S, Narayan SM, Roney CH
Heart Rhythm, Elsevier vol. 22 (4) 
01-04-2025
PO-05-068 DIGITAL TWIN STUDY ON ELECTROLYTE IMBALANCE AND THE INITIATION AND TERMINATION OF ATRIAL FIBRILLATION
Corrado C, Roney CH, Narayan SM, Giles WR, Niederer SA
Heart Rhythm, Elsevier vol. 22 (4) 
01-04-2025
PO-03-140 UNIPOLAR VOLTAGE MAPPING UNMASKS THE ARRHYTHMOGENIC ATRIAL SUBSTRATE AS DEPICTED BY CMR LGE
Valli H, Ehnesh M, Chen Z, Hussain W, Jones DG, Mohiaddin R, Wong T, Roney CH et al.
Heart Rhythm, Elsevier vol. 22 (4) 
01-04-2025
PO-05-017 A CONSENSUS BASED ELECTRO-OPTIC FLOW ABLATION STRATEGY FOR PERSISTENT AF
Jaffery OA, Barrera CE, Zolotarev A, Good WW, Rodero C, Slabaugh G, Vigmond EJ, Niederer S et al.
Heart Rhythm, Elsevier vol. 22 (4), s568-s569.  
01-04-2025
PO-03-005 PERSONALIZED ATRIAL FIBRILLATION TREATMENT USING PATIENT-SPECIFIC DIGITAL TWINS FROM NON-INVASIVE ELECTROCARDIOGRAPHIC IMAGING
Martín CH, Martínez-Pérez M, Lipe IL, López RM, Rodriguez MM, Arciniegas JPS, Alabau RM, Fambuena-Santos C et al.
Heart Rhythm, Elsevier vol. 22 (4) 
01-04-2025
PO-02-215 LINKING REGIONAL EPICARDIAL ADIPOSE TISSUE WITH REGIONAL MECHANICAL FUNCTION IN ATRIAL FIBRILLATION PATIENTS
Sillett C, Baptiste T, Razeghi O, Lee AW, Solis-Lemus JA, Roney CH, Feng R, Ganesan P et al.
Heart Rhythm, Elsevier vol. 22 (4) 
01-04-2025
PO-05-041 ARTIFICIALLY GENERATED FIBROSIS DISTRIBUTIONS IMPROVE PREDICTION OF ATRIAL FIBRILLATION ABLATION OUTCOME
Zolotarev A, Johnson KP, Alwazzan O, Vigmond EJ, Narayan SM, Slabaugh G, Niederer SA, Roney CH
Heart Rhythm, Elsevier vol. 22 (4) 
01-04-2025
Compositional Segmentation of Cardiac Images Leveraging Metadata
Khan A, Asad M, Benning M, Roney C, Slabaugh G
2025 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV). 
06-03-2025
CAMS: Convolution and Attention-Free Mamba-Based Cardiac Image Segmentation
Khan A, Asad M, Benning M, Roney C, Slabaugh G
2025 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV). 
06-03-2025
The Accuracy of Cardiac Surface Conduction Velocity Measurements
Vigmond EJ, Massé S, Roney CH, Bayer JD, Nanthakumar K
Jacc Clinical Electrophysiology, Elsevier vol. 11 (4), 694-705.  
15-01-2025
Identification of atrial myopathy and atrial fibrillation recurrence after ablation using 3D left atrial phasic strain from retrospective gated computed tomography
Sillett C, Razeghi O, Baptiste TMG, Lee AWC, Lemus JAS, Rodero C, Roney CH, Feng R et al.
European Heart Journal - Imaging Methods and Practice, Oxford University Press (Oup) vol. 3 (1) 
13-01-2025
Peak frequency can be effectively used to characterize scar in atrial fibrillation
Al-Aidarous S, Horrach CV, Roney C, Butcher C, Hunter RJ, Honarbakhsh S
Heart Rhythm O2, Elsevier vol. 6 (4), 434-443.  
09-01-2025
An Ensemble of 3D Residual Encoder UNet Models for Solving Multi-class Bi-atrial Segmentation Challenge
Zolotarev A, Johnson K, Khan A, Slabaugh G, Roney C
In Statistical Atlases and Computational Models of The Heart. Workshop, Cmrxrecon and Mbas Challenge Papers., Springer Nature 209-213.  
01-01-2025

2024

Quantification of atrial cardiomyopathy disease severity by electroanatomic voltage mapping and cardiac magnetic resonance imaging
Sim I, Lemus JAS, O'Shea C, Razeghi O, Whitaker J, Mukherjee R, O'Hare D, Fitzpatrick N et al.
Journal of Cardiovascular Electrophysiology, Wiley vol. 36 (2), 467-479.  
30-12-2024
Vector field heterogeneity as a novel omnipolar mapping metric for functional substrate characterization in scar-related ventricular tachycardias
Tonko JB, Ruipérez-Campillo S, Cabero-Vidal G, Cabrera-Borrego E, Roney C, Jiménez-Jáimez J, Millet J, Castells F et al.
Heart Rhythm, Elsevier vol. 22 (5), 1218-1228.  
07-11-2024
Compositional Segmentation of Cardiac Images Leveraging Metadata
Khan A, Asad M, Benning M, Roney C, Slabaugh G
In Arxiv 
30-10-2024
In-silico insights into personalised therapy selection of anti-arrhythmic drugs and ablation using patient-specific biatrial models for atrial fibrillation
Misghina S, Rauseo E, Barrera CE, Vigmond EJ, Slabaugh G, Aung N, Petersen SE, Munroe PB et al.
ESC 2024. 
28-10-2024
An in-silico comparison of anatomical and substrate based AF ablation using electro and optical flow mapping
Jaffery OA, Zolotarev A, Barera CE, Rodero C, Niederer S, Slabaugh G, Good WW, Roney CH
European Heart Journal, Oxford University Press (Oup) vol. 45 (Supplement_1), ehae666.579-ehae666.579.  
28-10-2024
Biventricular modelling for investigating ventricular arrhythmias in silico
Cheng F, Rauseo E, Misghina S, Barrera C, Vigmond E, Slabaugh G, Aung N, Petersen S et al.
ESC 2024. 
28-10-2024
The effect of fixed and functional remodelling on conduction velocity, wavefront propagation, and rotational activity formation in atrial fibrillation
Honarbakhsh S, Horrach CV, Lambiase PD, Roney C, Hunter RJ
Ep Europace, Oxford University Press (Oup) vol. 26 (10) 
16-09-2024
Autonomic modulation impacts conduction velocity dynamics and wavefront propagation in the left atrium
Honarbakhsh S, Roney C, Horrach CV, Lambiase PD, Hunter RJ
Ep Europace, Oxford University Press (Oup) vol. 26 (9) 
30-08-2024
Improving Access to Psilocybin-Assisted Therapy: Barriers, Challenges, and Recommendations
Tsang V, Roney C
European Psychiatry : The Journal of The Association of European Psychiatrists vol. 67 (Suppl 1), S601-S601.  
01-08-2024
Observable Atrial and Ventricular Fibrillation Episode Durations Are Conformant With a Power Law Based on System Size and Spatial Synchronization
Dharmaprani D, Tiver K, Shahrbabaki SS, Jenkins EV, Chapman D, Strong C, Quah JX, Tonchev I et al.
Circulation Arrhythmia and Electrophysiology, Wolters Kluwer vol. 17 (7) 
28-06-2024
CAMS: Convolution and Attention-Free Mamba-based Cardiac Image Segmentation
Khan A, Asad M, Benning M, Roney C, Slabaugh G
In Arxiv 
09-06-2024
Omnipolar conduction velocity mapping for ventricular substrate characterization: Impact of CV estimation method and EGM type on in vivo conduction velocity measurements
Tonko JB, Ehnesh M, Vigmond E, Chow A, Roney C, Lambiase PD
Heart Rhythm, Elsevier vol. 21 (12), 2499-2508.  
06-06-2024
Crop and Couple: Cardiac Image Segmentation Using Interlinked Specialist Networks
Khan A, Asad M, Benning M, Roney C, Slabaugh G
2024 IEEE International Symposium on Biomedical Imaging (ISBI). 
30-05-2024
Effects of different types of fibrotic remodelling in areas of low voltage on atrial fibrillation dynamics: an in-silico study
Horrach CV, Jaffery OA, Hunter RJ, Honarbakhsh S, Roney C
Ep Europace, Oxford University Press (Oup) vol. 26 (Supplement_1) 
24-05-2024
Peak frequency can be effectively used to characterize atrial remodelling in atrial fibrillation
Al-Aidarous S, Horrach CV, Roney C, Butcher C, Hunter R, Honarbakhsh S
Ep Europace, Oxford University Press (Oup) vol. 26 (Supplement_1) 
24-05-2024
Enhancing OpenEP: atrial conduction velocity and conduction velocity heterogeneity quantification through EP Workbench
Vigneswaran V, Gharaviri AG, Klis MK, Bodagh NB, Sim IS, Roney CR, Kotadia IK, Niederer SN et al.
Ep Europace, Oxford University Press (Oup) vol. 26 (Supplement_1) 
24-05-2024
A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
Jaffery OA, Melki L, Slabaugh G, Good WW, Roney CH
Arrhythmia & Electrophysiology Review, Radcliffe Cardiology vol. 13 
20-05-2024
PO-05-033 PATIENT-SPECIFIC BIATRIAL MODELLING FRAMEWORK FOR PREDICTING ATRIAL FIBRILLATION OUTCOMES
Misghina SB, Solis-Lemus JA, Lopez-Barrera CE, Rauseo E, Vigmond EJ, Niederer SA, Aung N, Munroe PB et al.
Heart Rhythm, Elsevier vol. 21 (5), s565-s566.  
01-05-2024
PO-05-163 TOWARDS AUTOMATED GENERATION OF ABLATION LESION MASKS: A UNISON OF ELECTRO AND OPTIC FLOW MAPPING
Jaffery OA, Barrera CE, Rodero C, Zolotarev A, Good WW, Slabaugh G, Niederer S, Vigmond EJ et al.
Heart Rhythm Society. 
01-05-2024
PO-05-119 PEAK FREQUENCY CAN BE EFFECTIVELY USED TO CHARACTERIZE ATRIAL REMODELING IN ATRIAL FIBRILLATION
Al-Aidarous S, Horrach CV, Roney CH, Butcher C, Hunter RJ, Honarbakhsh S
Heart Rhythm, Elsevier vol. 21 (5), s529-s530.  
01-05-2024
PO-05-025 ANATOMICAL AND PHYSIOLOGICAL FEATURES IMPROVE AF ABLATION OUTCOME PREDICTION: A COMBINED DEEP LEARNING AND IN-SILICO APPROACH
Zolotarev A, Rodero C, Narayan SM, Vigmond EJ, Plank G, Niederer SA, Roney CH
Heart Rhythm, Elsevier vol. 21 (5), s561-s562.  
01-05-2024
PO-06-114 REDEFINING ATRIAL SUBSTRATE ASSESSMENT IN THE OMNIPOLAR MAPPING ERA
Valli H, Ehnesh M, Chen Z, Hussain W, Jones DG, Wong T, Roney CH, Haldar S
Heart Rhythm, Elsevier vol. 21 (5) 
01-05-2024
PO-05-031 THE DETERMINATION OF ABLATION TARGETS IN PATIENT-SPECIFIC ATRIAL MODELS IS INFLUENCED BY THE DATA USED FOR CALIBRATION.
Ehnesh M, Valli H, Zolotarev A, Jaffery OA, Barrera CL, Vigmond EJ, Haldar S, Roney CH
Heart Rhythm, Elsevier vol. 21 (5), s564-s565.  
01-05-2024
Multi-view Cardiac Image Segmentation via Trans-Dimensional Priors
Khan A, Asad M, Benning M, Roney C, Slabaugh G
In Arxiv 
25-04-2024
A three-dimensional left atrial motion estimation from retrospective gated computed tomography: application in heart failure patients with atrial fibrillation
Sillett C, Razeghi O, Lee AWC, Lemus JAS, Roney C, Mannina C, de Vere F, Ananthan K et al.
Frontiers in Cardiovascular Medicine, Frontiers vol. 11 
26-03-2024
Crop and Couple: cardiac image segmentation using interlinked specialist networks
Khan A, Asad M, Benning M, Roney C, Slabaugh G
In Arxiv 
14-02-2024
Does spatiotemporal dispersion indicate a patient-unique fingerprint or a generic characteristic of persistent atrial fibrillation?
Roney C, Honarbakhsh S
Heart Rhythm, Elsevier vol. 21 (5), 553-554.  
01-02-2024
Spatial and temporal relationship between focal and rotational activations and their relationship to structural remodeling in patients with persistent atrial fibrillation
Honarbakhsh S, Roney C, Wharmby A, Vidal Horrach C, Hunter RJ
Heart Rhythm, Elsevier vol. 21 (6), 752-761.  
28-01-2024
High Prevalence of New Clinically Significant Findings in Patients With Embolic Stroke of Unknown Source Evaluated by Cardiac Magnetic Resonance Imaging
Kotadia ID, O'Dowling R, Aboagye A, Crawley RJ, Bodagh N, Gharaviri A, O'Hare D, Solis‐Lemus JA et al.
Journal of The American Heart Association, Wolters Kluwer vol. 13 (3) 
19-01-2024
Predicting Atrial Fibrillation Treatment Outcome with Siamese Multi-modal Fusion and Cardiac Digital Twins
Zolotarev AM, Khan AKR, Slabaugh G, Roney CH
Medical Imaging with Deep Learning. 
01-01-2024
Misclassification Loss for Segmentation of the Aortic Vessel Tree
Khan A, Asad M, Zolotarev A, Roney C, Mathur A, Benning M, Slabaugh G
In Segmentation of The Aorta. Towards The Automatic Segmentation, Modeling, and Meshing of The Aortic Vessel Tree From Multicenter, Springer Nature 67-79.  
01-01-2024

2023

Constructing bilayer and volumetric atrial models at scale
Roney CH, Lemus JAS, Barrera CL, Zolotarev A, Ulgen O, Kerfoot E, Bevis L, Misghina S et al.
Interface Focus, The Royal Society vol. 13 (6), 20230038-20230038.  
15-12-2023
A Semi-automatic Pipeline for Generation of Large Cohorts of Four-Chamber Heart Meshes
Strocchi M, Rodero C, Roney CH, Mendonca Costa C, Plank G, Lamata P, Niederer SA
Methods in Molecular Biology, Springer Nature vol. 2735, 117-127.  
02-12-2023
Deep neural network architectures for cardiac image segmentation
El-Taraboulsi J, Cabrera CP, Roney C, Aung N
Artificial Intelligence in The Life Sciences, Elsevier vol. 4 
01-12-2023
Abstract 13321: Novel Regional Analysis of Left Atrial Strain From Computed Tomography Separates Patients With Persistent versus Paroxysmal Atrial Fibrillation
Sillett C, Razeghi O, Lee A, Lemus JAS, Roney C, Ganesan P, Feng R, Chubb H et al.
Circulation, Wolters Kluwer vol. 148 (Suppl_1), a13321-a13321.  
07-11-2023
AF and in-hospital mortality in COVID-19 patients
Kotadia ID, Dias M, Roney C, Parker RA, O’Dowling R, Bodagh N, Lemus-Solis J-A, O’Hare D et al.
Heart Rhythm O2, Elsevier vol. 4 (11), 700-707.  
16-10-2023
Subject-Specific Ablation of Pathologic Conduction Patterns Beyond the Pulmonary Veins: A Personalised Modelling Approach
Jaffery OA, Horrach CV, Lagalante DJ, Thomas G, Slabaugh G, Melki L, Good WW, Roney CH
2023 Computing in Cardiology Conference (CinC). 
04-10-2023
Patient-Specific Atrial Fibrillation Simulation Prediction Depend on Rhythm Used for Calibration
Horrach CV, Jaffery OA, Hunter RJ, Honarbakhsh S, Roney C
2023 Computing in Cardiology Conference (CinC). 
04-10-2023
Atrial Fibrosis Distribution Generation Based on the Diffusion Models
Zolotarev AM, Roney CH
2023 Computing in Cardiology Conference (CinC). 
04-10-2023
The Impact of Electrogram Type and Conduction Velocity Estimation Techniques on Assessments of Conduction Velocity During Ventricular Substrate Mapping
Ehnesh M, Tonko J, Zolotarev AM, Vigmond EJ, Lambiase PD, Roney C
2023 Computing in Cardiology Conference (CinC). 
04-10-2023
Biatrial Modelling for In Silico Prediction of Atrial Fibrillation Inducibility
Misghina SB, Solis-Lemus JA, Vigmond EJ, Niederer SA, Roney CH
2023 Computing in Cardiology Conference (CinC). 
04-10-2023
A personalized real-time virtual model of whole heart electrophysiology
Gillette K, Gsell MAF, Strocchi M, Grandits T, Neic A, Manninger M, Scherr D, Roney CH et al.
Ep Europace, Oxford University Press vol. 25 (Suppl 1), euad122.541-euad122.541.  
24-05-2023
In silico biatrial fibrosis ablation improves atrial fibrillation outcome
Roney C, Alonso JSL, Sim I, Ulgen O, Rodero C, Strocchi M, Kotadia I, Honarbakhsh S et al.
Ep Europace, Oxford University Press (Oup) vol. 25 (Supplement_1) 
24-05-2023
Atrial fibrillation and in-hospital mortality in Covid-19 patients
Kotadia I, Dias M, Roney C, Parker RA, O'dowling R, O'hare D, Solis-Lemus JA, Sim I et al.
Ep Europace, Oxford University Press (Oup) vol. 25 (Supplement_1) 
24-05-2023
In Atrial Fibrillation, Omnipolar Voltage Maps More Accurately Delineate Scar Than Bipolar Voltage Maps
Butcher C, Roney C, Wharmby A, Ahluwalia N, Chow A, Lambiase PD, Hunter RJ, Honarbakhsh S
Jacc Clinical Electrophysiology, Elsevier vol. 9 (8), 1500-1512.  
18-05-2023
Evaluation of an open-source pipeline to create patient-specific left atrial models: A reproducibility study
Solís-Lemus JA, Baptiste T, Barrows R, Sillett C, Gharaviri A, Raffaele G, Razeghi O, Strocchi M et al.
Computers in Biology and Medicine, Elsevier vol. 162, 107009-107009.  
16-05-2023
PO-03-103 OMNIPOLAR VOLTAGE MAPPING DURING AF EFFECTIVELY OVERCOMES THE IMPACT WAVEFRONT COLLISION AND FRACTIONATION HAS ON BIPOLAR VOLTAGE MAPS AND MORE EFFECTIVELY IDENTIFIES SITES OF PV RECONNECTION AT PREVIOUS WIDE AREA CIRCUMFERENTIAL LINES COMPARED TO BIPOLAR VOLTAGE MAPS
Butcher C, Roney CH, Ahluwalia N, Wharmby AL, Chow AW, Lambiase PD, Hunter RJ, Honarbakhsh S
Heart Rhythm, Elsevier vol. 20 (5) 
01-05-2023
PO-01-095 REGIONAL DIFFERENCES IN ATRIAL FIBER STRAINS IN HEART FAILURE PATIENTS WITH AND WITHOUT ATRIAL FIBRILLATION
Sillett C, Razeghi O, Lee AW, Solis-Lemus JA, Roney CH, Ennis D, Rinaldi CA, Rajani R et al.
Heart Rhythm, Elsevier vol. 20 (5) 
01-05-2023
PO-01-215 ATRIAL FIBRILLATION OUTCOME IS IMPROVED BY BIATRIAL SUBSTRATE ABLATION IN A LARGE VIRTUAL TRIAL
Roney CH, Solis-Lemus JA, Honarbakhsh S, Sim I, Rodero C, Strocchi M, Kotadia I, Narayan SM et al.
Heart Rhythm, Elsevier vol. 20 (5), s164-s165.  
01-05-2023
PO-02-172 CONDUCTION VELOCITY AND CONDUCTION VELOCITY DYNAMICS IN THE LEFT ATRIUM ARE IMPACTED BY STRUCTURAL AND AUTONOMIC MODULATION AND SITES OF CONDUCTION VELOCITY HETEROGENEITY CORRELATE TO RE-ENTRY ACTIVITY IN ATRIAL FIBRILLATION
Honarbakhsh S, Roney CH, Wharmby AL, Abbass H, Whittaker-Axon S, Lambiase PD, Hunter RJ
Heart Rhythm, Elsevier vol. 20 (5), s300-s301.  
01-05-2023
Atrial fibrillation ablation outcome prediction with a machine learning fusion framework incorporating cardiac computed tomography
Razeghi O, Kapoor R, Alhusseini MI, Fazal M, Tang S, Roney CH, Rogers AJ, Lee A et al.
Journal of Cardiovascular Electrophysiology, Wiley vol. 34 (5), 1164-1174.  
27-04-2023
Evaluation of an Open-Source Pipeline to Create Patient-Specific Left Atrial Models: A Reproducibility Study
Solis-Lemus JA, Baptiste T, Barrows R, Sillett C, Gharaviri A, Raffaele G, Razeghi O, Strocchi M et al.
In Arxiv 
17-01-2023
Quantifying the impact of shape uncertainty on predicted arrhythmias
Corrado C, Roney CH, Razeghi O, Lemus JAS, Coveney S, Sim I, Williams SE, O'Neill MD et al.
Computers in Biology and Medicine, Elsevier vol. 153, 106528-106528.  
03-01-2023
Effect of Varying Pericardial Boundary Conditions on Whole Heart Function: A Computational Study
Ghebryal J, Rodero C, Barrows RK, Strocchi M, Roney CH, Augustin CM, Plank G, Niederer SA
In Functional Imaging and Modeling of The Heart, Springer Nature 545-554.  
01-01-2023

2022

Fiber Organization Has Little Effect on Electrical Activation Patterns During Focal Arrhythmias in the Left Atrium
He J, Pertsov AM, Cherry EM, Fenton FH, Roney CH, Niederer SA, Zang Z, Mangharam R
Ieee Transactions On Biomedical Engineering, Institute of Electrical and Electronics Engineers vol. 70 (5), 1611-1621.  
18-11-2022
Fiber Organization has Little Effect on Electrical Activation Patterns during Focal Arrhythmias in the Left Atrium
He J, Pertsov AM, Cherry EM, Fenton FH, Roney CH, Niederer SA, Zang Z, Mangharam R
In Arxiv 
29-10-2022
Calibrating cardiac electrophysiology models using latent Gaussian processes on atrial manifolds
Coveney S, Roney CH, Corrado C, Wilkinson RD, Oakley JE, Niederer SA, Clayton RH
Scientific Reports, Nature Research vol. 12 (1), 16572-16572.  
04-10-2022
A personalized real-time virtual model of whole heart electrophysiology
Gillette K, Gsell MAF, Strocchi M, Grandits T, Neic A, Manninger M, Scherr D, Roney CH et al.
Frontiers in Physiology, Frontiers Media vol. 13, 907190-907190.  
23-09-2022
The inspection paradox: An important consideration in the evaluation of rotor lifetimes in cardiac fibrillation
Jenkins EV, Dharmaprani D, Schopp M, Quah JX, Tiver K, Mitchell L, Xiong F, Aguilar M et al.
Frontiers in Physiology, Frontiers Media vol. 13, 920788-920788.  
06-09-2022
Atrial conduction velocity mapping: clinical tools, algorithms and approaches for understanding the arrhythmogenic substrate
Coveney S, Cantwell C, Roney C
Medical & Biological Engineering & Computing, Springer Nature vol. 60 (9), 2463-2478.  
22-07-2022
Calibrating cardiac electrophysiology models using latent Gaussian processes on atrial manifolds
Coveney S, Roney CH, Corrado C, Wilkinson RD, Oakley JE, Niederer SA, Clayton RH
In Arxiv 
08-06-2022
OpenEP-Py and OpenEP-GUI: An interactive platform for the visualisation and analysis of clinical and simulated cardiac electrophysiology data
Smith P, Bishop M, Rajan J, Kerfoot E, Sim I, Kotadia I, O’hare D, Fitzpatrick N et al.
Ep Europace, Oxford University Press (Oup) vol. 24 (Supplement_1) 
19-05-2022
Interpolation of electrophysiology parameters using OpenEP: technology development and clinical application
Williams S, Roney C, Connolly A, Smith P, Bishop M, Niederer S, Whitaker J, Corrado C et al.
Ep Europace, Oxford University Press (Oup) vol. 24 (Supplement_1) 
19-05-2022
Atrial tissue characterisation using electroanatomic voltage mapping and cardiac magnetic resonance imaging
Sim I, Razeghi O, Lemus JS, Mukherjee R, O’hare D, O’neill L, Kotadia I, Roney C et al.
Ep Europace, Oxford University Press (Oup) vol. 24 (Supplement_1) 
19-05-2022
PO-616-05 THE INSPECTION PARADOX: AN IMPORTANT CONSIDERATION IN THE EVALUATION OF ROTOR LIFETIMES IN CARDIAC FIBRILLATION
Jenkins E, Dharmaprani D, Schopp M, Quah J, Tiver K, Xiong F, Aguilar M, Akar FG et al.
Heart Rhythm, Elsevier vol. 19 (5), s112-s112.  
28-04-2022
PO-664-05 LOCAL AREA STRAINS FROM RETROSPECTIVE GATED COMPUTED TOMOGRAPHY IMAGING TO DETECT ATRIAL FIBRILLATION
Sillett C, Razeghi O, Strocchi M, Roney CH, O'Brien H, Ennis D, Haberland U, Rajani R et al.
Heart Rhythm, Elsevier vol. 19 (5), s297-s298.  
28-04-2022
Detection of focal source and arrhythmogenic substrate from body surface potentials to guide atrial fibrillation ablation
Feng Y, Roney CH, Bayer JD, Niederer SA, Hocini M, Vigmond EJ
Plos Computational Biology, Public Library of Science (Plos) vol. 18 (3) 
21-03-2022
Predicting Atrial Fibrillation Recurrence by Combining Population Data and Virtual Cohorts of Patient-Specific Left Atrial Models
Roney CH, Sim I, Yu J, Beach M, Mehta A, Alonso Solis-Lemus J, Kotadia I, Whitaker J et al.
Circulation Arrhythmia and Electrophysiology, Wolters Kluwer vol. 15 (2) 
28-01-2022
Atrial CARdiac Magnetic resonance imaging in patients with embolic stroke of unknown source without documented Atrial Fibrillation (CARM-AF): Study design and clinical protocol
Kotadia ID, O’Dowling R, Aboagye A, Sim I, O’Hare D, Lemus-Solis J-A, Roney CH, Dweck M et al.
Heart Rhythm O2, Elsevier vol. 3 (2), 196-203.  
20-01-2022
A Workflow for Probabilistic Calibration of Models of Left Atrial Electrophysiology
Coveney S, Corrado C, Roney C, Wilkinson RD, Oakley JE, Niederer SA, Clayton RH
2022 Computing in Cardiology Conference (CinC). 
07-01-2022
In Vivo Analysis of Conduction Pattern Dynamics: System Development and Application Using OpenEP
Gharaviri A, O'Neill L, Smith P, Roney CH, Grubb N, Wright M, O'Neill M, Williams SE
2022 Computing in Cardiology Conference (CinC). 
07-01-2022
The Effect of Heart Rate and Atrial Contraction on Left Ventricular Function
Barrows RK, Strocchi M, Augustin CM, Gsell MAF, Roney CH, Solis-Lemus JA, Xu H, Gillette KK et al.
2022 Computing in Cardiology Conference (CinC). 
07-01-2022
The Inspection Paradox: An Important Consideration in the Evaluation of Rotor Lifetimes in Cardiac Fibrillation
Jenkins E, Dharmaprani D, Schopp M, Quah JX, Tiver K, Mitchell L, Xiong F, Aguilar M et al.
Heart Lung and Circulation, Elsevier vol. 31, s133-s134.  
01-01-2022

2021

Applications of multimodality imaging for left atrial catheter ablation
Roney CH, Sillett C, Whitaker J, Lemus JAS, Sim I, Kotadia I, O'Neill M, Williams SE et al.
European Heart Journal - Cardiovascular Imaging, Oxford University Press (Oup) vol. 23 (1), 31-41.  
08-11-2021
Late Gadolinium Enhancement Cardiovascular Magnetic Resonance Assessment of Substrate for Ventricular Tachycardia With Hemodynamic Compromise
Whitaker J, Neji R, Kim S, Connolly A, Aubriot T, Calvo JJ, Karim R, Roney CH et al.
Frontiers in Cardiovascular Medicine, Frontiers vol. 8 
26-10-2021
11 Clinical associations and pathological mechanisms of reduced atrial conduction velocity
O’Hare D, O’Neill L, Sim I, Kotadia I, Bendikas R, Roney C, Niederer S, Solis Lemus J et al.
Oral abstracts. 
01-10-2021
Time-Averaged Wavefront Analysis Demonstrates Preferential Pathways of Atrial Fibrillation, Predicting Pulmonary Vein Isolation Acute Response
Roney CH, Child N, Porter B, Sim I, Whitaker J, Clayton RH, Laughner JI, Shuros A et al.
Frontiers in Physiology, Frontiers vol. 12 
27-09-2021
B-PO02-137 OPEN-SOURCE PLATFORM FOR ANALYSIS OF FIBROSIS BEFORE AND AFTER A PULMONARY VEIN ISOLATION PROCEDURE
Solis-Lemus JA, Roney CH, Razeghi O, Sim I, Kotadia I, Mukherjee R, Williams SE, O'Neill M et al.
Heart Rhythm, Elsevier vol. 18 (8) 
01-08-2021
B-PO03-022 INTEGRATING ATRIAL CARDIAC MAGNETIC RESONANCE IMAGING AND ELECTROANATOMIC MAPPING DATA USING UNIVERSAL ATRIAL CO-ORDINATES AND OPENEP (AN OPEN-SOURCE FRAMEWORK FOR ELECTROPHYSIOLOGY RESEARCH)
Williams SE, Roney CH, Sim I, Kotadia I, Solis-Lemus JA, Razeghi O, Corrado C, Wright MJ et al.
Heart Rhythm, Elsevier vol. 18 (8) 
01-08-2021
B-PO03-096 DIELECTRIC IMAGING ACCURATELY MEASURES REGIONAL CARDIAC CHAMBER WALL THICKNESS - AN IN VIVO STUDY
Kotadia I, Williams ISM, Roney CH, Solis-Lemus J, Razeghi O, Daniel C, Clutton SGE, Grant RGL et al.
Heart Rhythm, Elsevier vol. 18 (8), s227-s228.  
27-07-2021
B-PO05-007 RAPID AND ROBUST MAPPING OF CLINICAL DATA ON PERSONALIZED VOLUMETRIC ATRIAL GEOMETRIES
Ali SY, Millare B, Bradley R, Ali RL, Boyle PM, Salvador M, Fedele M, Aronis KN et al.
Heart Rhythm, Elsevier vol. 18 (8), s374-s374.  
27-07-2021
B-PO05-012 PREDICTING ATRIAL FIBRILLATION RECURRENCE BY COMBINING POPULATION DATA & PATIENT-SPECIFIC MODELING
Roney CH, Sim I, Yu J, Beach M, Mehta A, Solis-Lemus J, Kotadia I, Whitaker J et al.
Heart Rhythm, Elsevier vol. 18 (8), s375-s376.  
27-07-2021
The Effect of Ventricular Myofibre Orientation on Atrial Dynamics
Strocchi M, Augustin CM, Gsell MAF, Karabelas E, Neic A, Gillette K, Roney CH, Razeghi O et al.
International Conference on Functional Imaging and Modeling of the Heart. 
18-06-2021
Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate
Bifulco SF, Scott GD, Sarairah S, Birjandian Z, Roney CH, Niederer SA, Mahnkopf C, Kuhnlein P et al.
Elife, Elife vol. 10 
04-05-2021
OpenEP: A Cross-Platform Electroanatomic Mapping Data Format and Analysis Platform for Electrophysiology Research
Williams SE, Roney CH, Connolly A, Sim I, Whitaker J, O’Hare D, Kotadia I, O’Neill L et al.
Frontiers in Physiology, Frontiers vol. 12 
26-02-2021
Using machine learning to identify local cellular properties that support re-entrant activation in patient-specific models of atrial fibrillation
Corrado C, Williams S, Roney C, Plank G, O’Neill M, Niederer S
Ep Europace, Oxford University Press (Oup) vol. 23 (Supplement_1), i12-i20.  
12-01-2021
Anisotropic cardiac conduction
Kotadia I, Whitaker J, Roney C, Niederer S, O’Neill M, Bishop M, Wright M
Arrhythmia and Electrophysiology Review vol. 9 
01-01-2021
Optimisation of Left Atrial Feature Tracking Using Retrospective Gated Computed Tomography Images
Sillett C, Razeghi O, Strocchi M, Roney CH, O’Brien H, Ennis DB, Haberland U, Rajani R et al.
 
01-01-2021
Using the Universal Atrial Coordinate System for MRI and Electroanatomic Data Registration in Patient-Specific Left Atrial Model Construction and Simulation
Beach M, Sim I, Mehta A, Kotadia I, O’Hare D, Whitaker J, Solis-Lemus JA, Razeghi O et al.
 
01-01-2021

2020

Fully Automatic Atrial Fibrosis Assessment Using a Multilabel Convolutional Neural Network
Razeghi O, Sim I, Roney CH, Karim R, Chubb H, Whitaker J, O’Neill L, Mukherjee R et al.
Circulation: Cardiovascular Imaging, American Heart Association vol. 13 (12), e011512-e011512.  
15-12-2020
Clinical translation of patient-specific organ level cardiac models
Costa CM, Roney C, Strocchi M, Razeghi O, Niederer S
In Modeling and Simulating Cardiac Electrical Activity, Iop Publishing 
01-12-2020
Abstract 14899: Personalized Computational Modeling Identifies Embolic Stroke of Undetermined Source Patients With Potential Arrhythmic Substrate
Bifulco S, Scott GD, Sarairah S, Birjandian Z, Roney C, Niederer SA, Mahnkopf C, Kuhnlein P et al.
Circulation, Wolters Kluwer vol. 142 (Suppl_3) 
17-11-2020
Left atrial enhancement correlates with myocardial conduction velocity in patients with persistent atrial fibrillation
Ali RL, Qureshi NA, Liverani S, Roney CH, Kim S, Lim PB, Tweedy JH, Cantwell CD et al.
Frontiers in Physiology, Frontiers Media 
12-11-2020
CemrgApp: An interactive medical imaging application with image processing, computer vision, and machine learning toolkits for cardiovascular research
Razeghi O, Solís-Lemus JA, Lee AWC, Karim R, Corrado C, Roney CH, de Vecchi A, Niederer SA
Softwarex, Elsevier vol. 12 
01-07-2020
P920Understanding arrhythmia mechanisms in patients with atrial septal defects
O\neill L, Sim I, O\hare D, Whitaker J, Mukherjee R, Roney C, Razeghi O, Niederer S et al.
Ep Europace, Oxford University Press (Oup) vol. 22 (Supplement_1) 
01-06-2020
Constructing a Human Atrial Fibre Atlas
Roney CH, Bendikas R, Pashakhanloo F, Corrado C, Vigmond EJ, McVeigh ER, Trayanova NA, Niederer SA
Annals of Biomedical Engineering, Springer Nature vol. 49 (1), 233-250.  
26-05-2020
An audit of uncertainty in multi-scale cardiac electrophysiology models
Clayton RH, Aboelkassem Y, Cantwell CD, Corrado C, Delhaas T, Huberts W, Lei CL, Ni H et al.
Philosophical Transactions of The Royal Society a Mathematical Physical and Engineering Sciences, The Royal Society vol. 378 (2173) 
25-05-2020
Creation and application of virtual patient cohorts of heart models
Niederer SA, Aboelkassem Y, Cantwell CD, Corrado C, Coveney S, Cherry EM, Delhaas T, Fenton FH et al.
Philosophical Transactions of The Royal Society a Mathematical Physical and Engineering Sciences, The Royal Society vol. 378 (2173) 
25-05-2020
Gaussian process manifold interpolation for probabilistic atrial activation maps and uncertain conduction velocity
Coveney S, Corrado C, Roney CH, OHare D, Williams SE, ONeill MD, Niederer SA, Clayton RH et al.
Philosophical Transactions of The Royal Society a Mathematical Physical and Engineering Sciences, The Royal Society vol. 378 (2173) 
25-05-2020
Ventricular fibrillation mechanism and global fibrillatory organization are determined by gap junction coupling and fibrosis pattern
Handa BS, Li X, Baxan N, Roney CH, Shchendrygina A, Mansfield CA, Jabbour RJ, Pitcher DS et al.
Cardiovascular Research, Oxford University Press (Oup) vol. 117 (4), 1078-1090.  
13-05-2020
Gaussian Process Manifold Interpolation for Probabilistic Atrial Activation Maps and Uncertain Conduction Velocity
Coveney S, Corrado C, Roney CH, O'Hare D, Williams SE, O'Neill MD, Niederer SA, Clayton RH et al.
In Arxiv 
22-04-2020
Challenges Associated with Interpreting Mechanisms of AF
Roney CH, Wit AL, Peters NS
Arrhythmia & Electrophysiology Review, Radcliffe Cardiology vol. 8 (4), 273-284.  
11-02-2020
Constructing Realistic Canine Bilayer Biatrial Mesh for the Modeling and Simulation of Atria Fibrillation
Saha M, Roney C, Xiong F, Cochet H, Tan S, Niederer S, Vigmond E, Nattel S
2020 Computing in Cardiology Conference (CinC). 
16-01-2020
Robust Atrial Ectopic Beat Classification From Surface ECG Using Second-Order Blind Source Separation
Feng Y, Roney C, Hocini M, Niederer S, Vigmond E
2020 Computing in Cardiology Conference (CinC). 
16-01-2020
Constructing Virtual Patient Cohorts for Simulating Atrial Fibrillation Ablation
Roney CH, Beach M, Mehta A, Sim I, Corrado C, Bendikas R, Solis-Lemus JA, Razeghi O et al.
2020 Computing in Cardiology Conference (CinC). 
16-01-2020
Software Framework to Quantify Pulmonary Vein Isolation Atrium Scar Tissue
Solis-Lemus JA, Razeghi O, Roney C, Sim I, Mukherjee R, Williams S, O'Neill M, Niederer S
2020 Computing in Cardiology Conference (CinC). 
16-01-2020
In silico Comparison of Left Atrial Ablation Techniques That Target the Anatomical, Structural, and Electrical Substrates of Atrial Fibrillation
Roney CH, Beach ML, Mehta AM, Sim I, Corrado C, Bendikas R, Solis-Lemus JA, Razeghi O et al.
Frontiers in Physiology vol. 11 
01-01-2020
Probabilistic Interpolation of Uncertain Local Activation Times on Human Atrial Manifolds
Coveney S, Clayton RH, Corrado C, Roney CH, Wilkinson RD, Oakley JE, Lindgren F, Williams SE et al.
Ieee Transactions On Biomedical Engineering vol. 67 
01-01-2020
Quantifying atrial anatomy uncertainty from clinical data and its impact on electro-physiology simulation predictions
Corrado C, Razeghi O, Roney C, Coveney S, Williams S, Sim I, O’Neill M, Wilkinson R et al.
Medical Image Analysis vol. 61 
01-01-2020
Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium
Strocchi M, Gsell MAF, Augustin CM, Razeghi O, Roney CH, Prassl AJ, Vigmond EJ, Behar JM et al.
Journal of Biomechanics vol. 101 
01-01-2020
Using cardiac ionic cell models to interpret clinical data
Corrado C, Avezzù A, Lee AWC, Mendoca Costa C, Roney CH, Strocchi M, Bishop M, Niederer SA
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 
01-01-2020

2019

An Automated Platform to Standardize Position in the Left Atrium and Map Electrophysiological Data
Meo M, Duchateau J, Bayer J, Pambrun T, Roney CH, Vigmond EJ, Derval N, Denis A et al.
2019 Computing in Cardiology Conference (CinC). 
30-12-2019
Myocardial Transmural Electrical Disruption Affects Electrogram Pattern
Saha M, Roney C, Cochet H, Niederer S, Vigmond E, Nattel S
2019 Computing in Cardiology Conference (CinC). 
30-12-2019
Standardised Framework for Quantitative Analysis of Fibrillation Dynamics
Li X, Roney CH, Handa BS, Chowdhury RA, Niederer SA, Peters NS, Ng FS
Scientific Reports, Springer Nature vol. 9 (1) 
13-11-2019
4969Enhanced gap junction coupling organised and terminated acute ventricular fibrillation in ex-vivo perfused hearts
Handa BS, Li X, Roney C, Pitcher D, Chowdhury RA, Peter NS, Ng FS
European Heart Journal, Oxford University Press (Oup) vol. 40 (Supplement_1) 
01-10-2019
58 Characterisation of the structural and electrical impact of an atrial septal defect
O’Neill L, Sim I, O’Hare D, Flyod C, Roney C, Whitaker J, Mukherjee R, Razeghi O et al.
Brian Maurer Young Investigator Award. 
01-10-2019
Myocardial Transmural Electrical Disruption Affects Electrogram Pattern
Saha M, Roney C, Cochet H, Niederer S, Vigmond E, Nattel S
 
01-09-2019
An Automated Platform to Standardize Position in the Left Atrium and Map Electrophysiological Data
Meo M, Hocini M, Haïssaguerre M, Dubois R, Duchâteau J, Bayer J, Pambrun T, Roney CH et al.
 
01-09-2019
Fundamentals of cardiac mapping
Ng FS, Roney C, Cantwell CD, Peters NS
In Cardiac Mapping 70-83.  
05-04-2019
A technique for measuring anisotropy in atrial conduction to estimate conduction velocity and atrial fibre direction
Roney CH, Whitaker J, Sim I, O’Neill L, Mukherjee RK, Razeghi O, Vigmond EJ, Wright M et al.
Computers in Biology and Medicine vol. 104 
01-01-2019
Acetylcholine Delays Atrial Activation to Facilitate Atrial Fibrillation
Bayer JD, Boukens BJ, Krul SPJ, Roney CH, Driessen AHG, Berger WR, van den Berg NWE, Verkerk AO et al.
Frontiers in Physiology vol. 10 
01-01-2019
Cardiac propagation pattern mapping with vector field for helping tachyarrhythmias diagnosis with clinical tridimensional electro-anatomical mapping tools
Dallet C, Roney C, Martin R, Kitamura T, Puyo S, Duchateau J, Dumas-Pomier C, Ravon G et al.
Ieee Transactions On Biomedical Engineering vol. 66 
01-01-2019
Left atrial effective conducting size predicts atrial fibrillation vulnerability in persistent but not paroxysmal atrial fibrillation
Williams SE, O’Neill L, Roney CH, Julia J, Metzner A, Reißmann B, Mukherjee RK, Sim I et al.
Journal of Cardiovascular Electrophysiology 
01-01-2019
Preventing recurrence through analysing recurrence
Roney CH, Bishop MJ
Journal of Cardiovascular Electrophysiology vol. 30 
01-01-2019
Reproducibility of Atrial Fibrosis Assessment Using CMR Imaging and an Open Source Platform
Sim I, Razeghi O, Karim R, Chubb H, Whitaker J, O’Neill L, Mukherjee RK, Roney CH et al.
Jacc: Cardiovascular Imaging vol. 12 
01-01-2019
Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes
Roney CH, Pashaei A, Meo M, Dubois R, Boyle PM, Trayanova NA, Cochet H, Niederer SA et al.
Medical Image Analysis vol. 55 
01-01-2019

2018

Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes
Roney CH, Pashaei A, Meo M, Dubois R, Boyle PM, Trayanova NA, Cochet H, Niederer SA et al.
In Arxiv 
15-10-2018
116Inter and intra-observer reproducibility of atrial fibrosis assessment using late gadolinium enhanced cardiac magnetic resonance imaging
Sim I, Razeghi O, O'Neill L, Whitaker J, Mukherjee R, Roney C, Razavi R, O'Neill M et al.
Ep Europace vol. 20 (suppl_4), iv50-iv51.  
01-10-2018
Analytical approaches for myocardial fibrillation signals
Handa BS, Roney CH, Houston C, Qureshi NA, Li X, Pitcher DS, Chowdhury RA, Lim PB et al.
Computers in Biology and Medicine vol. 102 
01-01-2018
Characterisation of re-entrant circuit (or rotational activity) in vitro using the HL1-6 myocyte cell line
Houston C, Tzortzis KN, Roney C, Saglietto A, Pitcher DS, Cantwell CD, Chowdhury RA, Ng FS et al.
Journal of Molecular and Cellular Cardiology vol. 119 
01-01-2018
Determinants of new wavefront locations in cholinergic atrial fibrillation
Roney CH, Ng FS, Debney MT, Eichhorn C, Nachiappan A, Chowdhury RA, Qureshi NA, Cantwell CD et al.
Europace vol. 20 
01-01-2018
Patient-specific simulations predict efficacy of ablation of interatrial connections for treatment of persistent atrial fibrillation
Roney CH, Williams SE, Cochet H, Mukherjee RK, O’Neill L, Sim I, Whitaker J, Razeghi O et al.
Europace vol. 20 
01-01-2018
Repolarization abnormalities unmasked with exercise in sudden cardiac death survivors with structurally normal hearts
Leong KMW, Ng FS, Roney C, Cantwell C, Shun-Shin MJ, Linton NWF, Whinnett ZI, Lefroy DC et al.
Journal of Cardiovascular Electrophysiology vol. 29 
01-01-2018
Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation: Results from the STARLIGHT Study
Child N, Clayton RH, Roney CH, Laughner JI, Shuros A, Neuzil P, Petru J, Jackson T et al.
Circulation: Arrhythmia and Electrophysiology vol. 11 
01-01-2018
Variability in pulmonary vein electrophysiology and fibrosis determines arrhythmia susceptibility and dynamics
Roney CH, Bayer JD, Cochet H, Meo M, Dubois R, Jaïs P, Vigmond EJ
Plos Computational Biology vol. 14 
01-01-2018
Wavelength and fibrosis affect phase singularity locations during atrial fibrillation
Saha M, Roney CH, Bayer JD, Meo M, Cochet H, Dubois R, Vigmond EJ
Frontiers in Physiology vol. 9 
01-01-2018

2017

P4350Slowing of conduction by acetylcholine shortens the wavelength for reentrant atrial arrhythmias
Bayer JD, Boukens BJ, Roney CH, Vigmond EJ, Krul SPJ, Driessen AHG, Berger WR, Van Den Berg NWE et al.
European Heart Journal, Oxford University Press (Oup) vol. 38 (suppl_1) 
01-08-2017
Rotor Tracking Using Phase of Electrograms Recorded During Atrial Fibrillation
Roney CH, Cantwell CD, Qureshi NA, Chowdhury RA, Dupont E, Lim PB, Vigmond EJ, Tweedy JH et al.
Annals of Biomedical Engineering vol. 45 
01-01-2017
Spatial Resolution Requirements for Accurate Identification of Drivers of Atrial Fibrillation
Roney CH, Cantwell CD, Bayer JD, Qureshi NA, Lim PB, Tweedy JH, Kanagaratnam P, Peters NS et al.
Circulation: Arrhythmia and Electrophysiology vol. 10 
01-01-2017
ST-elevation magnitude correlates with right ventricular outflow tract conduction delay in Type I Brugada ECG
Leong KMW, Ng FS, Yao C, Roney C, Taraborrelli P, Linton NWF, Whinnett ZI, Lefroy DC et al.
Circulation: Arrhythmia and Electrophysiology vol. 10 
01-01-2017
The combination of pulmonary vein electrophysiology and atrial fibrosis determines driver location
Roney CH, Bayer JD, Dubois R, Meo M, Cochet H, Jäis P, Vigmond EJ
 
01-01-2017

2016

Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms
Roney CH, Bayer JD, Zahid S, Meo M, Boyle PM, Trayanova NA, Haïssaguerre M, Dubois R et al.
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of The Working Groups On Cardiac Pacing, Arrhyt vol. 18 
01-01-2016
Novel radiofrequency ablation strategies for terminating atrial fibrillation in the left atrium: A simulation study
Bayer JD, Roney CH, Pashaei A, Jaïs P, Vigmond EJ
Frontiers in Physiology vol. 7 
01-01-2016

2015

67 Dynamic Characterisation of the Electrophysiological Substrate in Brugada Syndrome During Physiological Autonomic Stimulation
Leong KMW, Ng FS, Roney C, Lim PB, Peters NS, Varnava A, Kanagaratnam P
Heart, Bmj vol. 101 (Suppl 4) 
01-06-2015
A technique for visualising three-dimensional left atrial cardiac activation data in two dimensions with minimal distance distortion
Roney CH, Tzortzis KN, Cantwell CD, Qureshi NA, Ali RL, Lim PB, Siggers JH, Ng FS et al.
 
01-01-2015
Automated fiducial point selection for reducing registration error in the co-localisation of left atrium electroanatomic and imaging data
Ali RL, Cantwell CD, Qureshi NA, Roney CH, Lim PB, Sherwin SJ, Siggers JH, Peters NS
 
01-01-2015
Influence of left atrial geometry on rotor core trajectories in a model of atrial fibrillation
Tzortzis KN, Roney CH, Qureshi NA, Ng FS, Lim PB, Sherwin SJ, Peters NS, Cantwell CD
 
01-01-2015
Techniques for automated local activation time annotation and conduction velocity estimation in cardiac mapping
Cantwell CD, Roney CH, Ng FS, Siggers JH, Sherwin SJ, Peters NS
Computers in Biology and Medicine vol. 65 
01-01-2015

2014

A novel method for quantifying localised correlation of late-gadolinium intensity with conduction velocity
Ali RL, Cantwell CD, Roney CH, Qureshi NA, Lim PB, Siggers JH, Sherwin SJ, Peters NS
 
01-01-2014
A novel method for rotor tracking using bipolar electrogram phase
Roney CH, Cantwell CD, Siggers JH, Ng FS, Peters NS
 
01-01-2014
A software platform for the comparative analysis of electroanatomic and imaging data including conduction velocity mapping
Cantwell CD, Roney CH, Ali RL, Qureshi NA, Lim PB, Peters NS
 
01-01-2014
An automated algorithm for determining conduction velocity, wavefront direction and origin of focal cardiac arrhythmias using a multipolar catheter
Roney CH, Cantwell CD, Qureshi NA, Ali RL, Chang ETY, Lim PB, Sherwin SJ, Peters NS et al.
 
01-01-2014

2013

The contact electrogram and its architectural determinants in atrial fibrillation
Zaman JA, Al-Aidarous S, Patel PM, Debney MT, Roney C, Chang ET, Chowdhury RA, Peters N
The Lancet, Elsevier vol. 381 
01-02-2013

2012

117 Conduction block induced by acidosis in HL-1 mouse atrial myocytes can be reversed by administering the gap junctional coupler rotigaptide
Al-Aidarous SI, Roney CH, Peters FMD, Ng FS, Chowdhury RA, Peters NS
Heart, Bmj vol. 98 (Suppl 1) 
01-05-2012

Right atrial dilatation associates with conduction velocity, incidence of arrhythmias and clinical outcomes in pulmonary hypertension

In Medrxiv 
Computational Modeling Identifies Embolic Stroke of Undetermined Source Patients with Potential Arrhythmic Substrate
Bifulco SF, Scott GD, Sarairah S, Birjandian Z, Roney CH, Niederer SA, Mahnkopf C, Kuhnlein P et al.
In Medrxiv 
Fiber Organization has Little Effect on Electrical Activation Patterns during Focal Arrhythmias in the Left Atrium.
He J, Pertsov AM, Cherry EM, Fenton FH, Roney CH, Niederer SA, Zang Z, Mangharam R
In Arxiv 
Spatial and temporal relationship between focal and rotational drivers and their relationship to structural remodeling in patients with persistent AF
Honarbakhsh S, Roney C, Wharmby A, Horrach CV, Hunter RJ
In Medrxiv 
The Accuracy of Cardiac Surface Conduction Velocity Measurements
Vigmond EJ, Roney C, Bayer J, Nanthakumar K
In Medrxiv 

Grants

solid heart iconGrants of specific relevance to Predictive in vitro Models
bullet iconDevelopment and Validation of Smartphone-Based Tools for Characterisation of Gait - QMUL-HUMA KTP
Caroline Roney, Zion Tse, James Scales, Greg Slabaugh, Dylan Morrissey, Stuart Miller and Trevor Prior
£227,485 Innovate UK
01-08-2024 - 31-07-2026
solid heart iconEPSRC Centre for Doctoral Training in Next Generation Organ-on-a-Chip Technology (COaCT)
Hazel Screen, Martin Knight, Thomas Iskratsch, Caroline Roney, Yi Sui, David Lee, Julia Shelton, Zion Tse, John Connelly, Adrian Biddle and Lucy Norling
£7,066,811 Engineering and Physical Sciences Research Council 
Grant Summary

01-07-2024 - 30-09-2032
bullet iconMapping populations to patients: designing optimal ablation therapy for atrial fibrillation through simulation and deep learning of digital twins (UKRI Future Leaders Fellowship)
Caroline Roney
£1,224,259 Medical Research Council
01-11-2022 - 31-05-2027

bullet iconSimulation and Mapping of Atrial Fibrillation Sources: Enhancing Catheter Ablation Strategies
Caroline Roney
£15,000 RHYTHM AI LTD
19-05-2025 - 31-08-2025
bullet iconSimplifying range of movement measurement in humans at home
Dylan Morrissey, Stuart Miller and Caroline Roney
£158,222 Huma Therapeutics Limited
01-03-2023 - 30-11-2023
bullet iconVirtual Atria with Personalised Electrophysiology for Atrial Fibrillation Therapy Planning
Caroline Roney and Thomas Iskratsch
£25,000 Acutus Medical UK Ltd
01-10-2022 - 30-09-2025
bullet iconFellowship: Predicting atrial fibrillation mechanisms through deep learning
Caroline Roney
£95,574 MRC Medical Research Council
18-10-2021 - 31-10-2022