Dr Chloe Stewart

Chloe Stewart
PhD, MPharm

Postdoctoral Research Assistant

School of Engineering & Materials Science
Queen Mary University of London
ORCID LinkedIn

Research

Organ-chip models, Hydrogels, Biomaterials, Spatial patterning, Musculoskeletal

Underpinning Bioengineering, Musculoskeletal Models

Interests

I use manufacturing techniques to recapitulate complex tissue environments within human organ-on-a-chip models. The spatial arrangement of human tissue varies both within and across tissues and is critical to maintaining normal function. To ensure that organ-chip models can capture the intricate variation in tissue architecture, I utilise novel approaches to incorporate spatial heterogeneity and cross-tissue interfaces into these models for enhanced physiological relevance and greater predictive power.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2024

Stewart CL, Hook AL, Zelzer M, Marlow M and Piccinini AM (2024). Cellular and microenvironmental cues that promote macrophage fusion and foreign body response. Frontiers  Frontiers in Immunology  vol. 15,  
Stewart CL, Hook AL, Zelzer M, Marlow M and Piccinini AM (2024). PLGA‐PEG‐PLGA hydrogels induce cytotoxicity in conventional in vitro assays. Wiley  Cell Biochemistry and Function  vol. 42, (5)