Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues
Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L, Golding M, Blacksell IA, Giblin MJ, Jaworska E, Bishop CL, Voisin M-B, Gaston-Massuet C, Fossati-Jimack L, Pitzalis C, Cooper D, Nightingale TD, Lopez-Otin C, Lewis MJ and Nourshargh S
Embo Reports, Springer Nature vol. 25 (9), 3842-3869.  
25-06-2024

β1-Integrin-Mediated Uptake of Chondrocyte Extracellular Vesicles Regulates Chondrocyte Homeostasis
Hussain MT, Austin-Williams S, Wright TD, Dhawan UK, Pinto AL, Cooper D and Norling LV
International Journal of Molecular Sciences, Mdpi vol. 25 (9) 
26-04-2024

The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing.
Fu H, Vuononvirta J, Fanti S, Bonacina F, D’Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi M, Grevitt P, Madeeha S, Egle S, Godinho S, Bombardieri M, Smith D, Cooper D, Asif I, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD and Marelli-Berg F
, Editors: Figliuolo ML. Nature Metabolism, Nature Research 
26-10-2023

A possible role for G-quadruplexes formation and DNA methylation at IMOOD gene promoter in Obsessive Compulsive Disorder
Sabatucci A, Girella A, Di Bartolomeo M, Pucci M, Vismara M, Benatti B, Blacksell IA, Cooper D, Dainese E, D'Acquisto F, Dell'Osso B and D'Addario C
Advances in Biological Regulation, Elsevier vol. 89 
01-08-2023

Being old and female is an inflammatory combination
Norling LV and Cooper D
Journal of Leukocyte Biology, Oxford University Press (Oup) vol. 114 (4), 299-300.  
04-07-2023

Peripheral control of psychiatric disorders: Focus on OCD. Are we there yet?
D'Acquisto F, D'Addario C, Cooper D, Pallanti S and Blacksell I
Comprehensive Psychiatry, Elsevier vol. 123 
06-04-2023

Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease
Poston RN, Chughtai J, Ujkaj D, Louis H, Leake DS and Cooper D
Biomedicines, Mdpi vol. 10 (12) 
30-11-2022

Galectin-9: A novel promoter of atherosclerosis progression
Krautter F, Hussain MT, Zhi Z, Lezama DR, Manning JE, Brown E, Marigliano N, Raucci F, Recio C, Chimen M, Maione F, Tiwari A, McGettrick HM, Cooper D, Fisher EA and Iqbal AJ
Atherosclerosis, Elsevier vol. 363, 57-68.  
19-11-2022

The immunomodulatory effects of social isolation in mice are linked to temperature control
Hamilton A, Rizzo R, Brod S, Ono M, Perretti M, Cooper D and D'Acquisto F
Brain Behavior and Immunity, Elsevier vol. 102, 179-194.  
22-02-2022

Methods for Assessing the Effects of Galectins on Leukocyte Trafficking and Clearance
Law HL and Cooper D
In Galectins, Springer Nature 581-601.  
01-01-2022

Galectin‐9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin‐dependent manner
Iqbal AJ, Krautter F, Blacksell IA, Wright RD, Austin‐Williams SN, Voisin M, Hussain MT, Law HL, Niki T, Hirashima M, Bombardieri M, Pitzalis C, Tiwari A, Nash GB, Norling LV and Cooper D
The Faseb Journal, Wiley vol. 36 (1) 
30-11-2021

Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis
Chen J, Norling LV, Mesa JG, Silva MDP, Burton SE, Reutelingsperger C, Perretti M and Cooper D
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 118 (38) 
15-09-2021

Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation
Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS, Gonzalez-Nuñez M, Austin-Williams SN, Cooper D, Vázquez-Martínez L, Fu T, De Rossi G, Golding M, Voisin M-B, Boulanger CM, Kubota Y, Muller WA, Tooze SA, Nightingale TD, Collinson L, Perretti M, Aksoy E and Nourshargh S
Immunity, Elsevier vol. 54 (9), 1989-2004.e9.  
06-08-2021

Cardiac Dysfunction in Rheumatoid Arthritis: The Role of Inflammation
Chen J, Norling LV and Cooper D
Cells, Mdpi vol. 10 (4) 
13-04-2021

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
Oggero S, de Gaetano M, Marcone S, Fitzsimons S, Pinto AL, Ikramova D, Barry M, Burke D, Montero‐Melendez T, Cooper D, Burgoyne T, Belton O, Norling LV, Brennan EP, Godson C and Perretti M
Journal of Extracellular Vesicles, Wiley vol. 10 (6) 
01-04-2021

CASTLE: cell adhesion with supervised training and learning environment
Gilbert SG, Krautter F, Cooper D, Chimen M, Iqbal AJ and Spill F
Journal of Physics D: Applied Physics, Iop Publishing vol. 53 (42), 424002-424002.  
29-07-2020

A pro-resolving role for Galectin-1 in acute inflammation
Norling L, Cooper D, Law H, Wright R and Iqbal A
Frontiers in Pharmacology, Frontiers Media vol. 11 (274) 
20-03-2020

Correction of Defective T-Regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α
Goldberg R, Scotta C, Cooper D, Nissim-Eliraz E, Nir E, Tasker S, Irving PM, Sanderson J, Lavender P, Ibrahim F, Corcoran J, Prevost T, Shpigel NY, Marelli-Berg F, Lombardi G and Lord GM
Gastroenterology, Elsevier vol. 156 (6), 1775-1787.  
30-01-2019

Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation
Gittens BR, Bodkin JV, Nourshargh S, Perretti M and Cooper D
The Journal of Immunology, The American Association of Immunologists vol. 198 (11), 4458-4469.  
01-06-2017

Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-ischemic pain by activation of pro-resolving pathways
Piovezan AP, Batisti AP, Benevides MLACS, Turnes BL, Martins DF, Kanis L, Duarte ECW, Cavalheiro AJ, Bueno PCP, Seed MP, Norling LV, Cooper D, Headland S, Souza PRPS and Perretti M
Journal of Ethnopharmacology, Elsevier vol. 204, 179-188.  
13-04-2017

OP028 Gut specific regulatory T cells – a new frontier for Crohn's disease therapy
Goldberg R, Scotta C, Cooper D, Eliraz E, Nir E, Irving P, Sanderson J, Shpigel N, Marelli-Berg F, Lombardi G and Lord G
Journal of Crohn's and Colitis, Oxford University Press (Oup) vol. 11 (suppl_1), s17-s17.  
26-01-2017

Immune resolution mechanisms in inflammatory arthritis.
Perretti M, Cooper D, Dalli J and Norling LV
Nat Rev Rheumatol vol. 13 (2), 87-99.  
05-01-2017

Expression of a chimeric antigen receptor specific for donor HLA class I enhances the potency of human regulatory T cells in preventing human skin transplant rejection.
Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM, Lechler RI, Maher J, Smyth LA and Lombardi G
Am J Transplant 
27-12-2016

Galectin-3-null mice display defective neutrophil clearance during acute inflammation.
Wright RD, Souza PR, Flak MB, Thedchanamoorthy P, Norling LV and Cooper D
, Editors: Montaner LJ. J Leukoc Biol, The Society For Leukocyte Biology 
12-10-2016

Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo
Iqbal AJ, Barrett TJ, Taylor L, McNeill E, Manmadhan A, Recio C, Carmineri A, Brodermann MH, White GE, Cooper D, DiDonato JA, Zamanian-Daryoush M, Hazen SL, Channon KM, Greaves DR and Fisher EA
Elife vol. 5 
30-08-2016

Abstract 575: Acute Exposure to Apolipoprotein AI Inhibits Macrophage and Macrophage Chemotaxis i n vitro and Recruitment i n vivo
Barrett TJ, Iqbal AJ, Taylor L, McNeill E, Manmadhan A, White GE, Cooper D, DiDonato JA, Hazen SL, Greaves DR and Fisher EA
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 36 (suppl_1) 
01-05-2016

Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment
Holloway PM, Durrenberger PF, Trutschl M, Cvek U, Cooper D, Orr AW, Perretti M, Getting SJ and Gavins FNE
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 35 (9), 1936-1944.  
25-06-2015

Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release
Komarowska I, Coe D, Wang G, Haas R, Mauro C, Kishore M, Cooper D, Nadkarni S, Fu H, Steinbruchel DA, Pitzalis C, Anderson G, Bucy P, Lombardi G, Breckenridge R and Marelli-Berg FM
Immunity, Elsevier vol. 42 (6), 1087-1099.  
01-06-2015

Glycobiology of leukocyte trafficking in inflammation.
Wright RD and Cooper D
Glycobiology vol. 24 (12), 1242-1251.  
01-12-2014

Methods for Assessing the Effects of Galectins on Leukocyte Trafficking
Gittens BR, Wright RD and Cooper D
Methods in Molecular Biology, Springer Nature vol. 1207, 133-151.  
25-08-2014

Resolution of inflammation: examples of peptidergic players and pathways.
Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D and Perretti M
Drug Discov Today vol. 19 (8), 1166-1171.  
01-08-2014

Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation.
Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ, Cooper D, Perretti M and Marelli-Berg FM
Nat Commun vol. 5 
14-03-2014

The role of Galectin-1 and Galectin-3 in the mucosal immune response to Citrobacter rodentium infection.
Curciarello R, Steele A, Cooper D, MacDonald TT, Kruidenier L and Kudo T
Plos One vol. 9 (9) 
01-01-2014

Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation
Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ, Cooper D, Perretti M and Marelli-Berg FM
Immunology vol. 143, 124-124.  
01-01-2014

Endogenous galectin-1 exerts tonic inhibition on experimental arthritis.
Iqbal AJ, Cooper D, Vugler A, Gittens BR, Moore A and Perretti M
J Immunol vol. 191 (1), 171-177.  
01-07-2013

Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function.
Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M and Fantuzzi G
Obesity (Silver Spring) vol. 21 (2), 310-319.  
01-02-2013

Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice.
Pang J, Rhodes DH, Pini M, Akasheh RT, Castellanos KJ, Cabay RJ, Cooper D, Perretti M and Fantuzzi G
Plos One vol. 8 (2) 
01-01-2013

The peritoneal tumour microenvironment of high-grade serous ovarian cancer.
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D, Ennis DP, Lockley M, McNeish IA, Nourshargh S and Balkwill FR
J Pathol vol. 227 (2), 136-145.  
01-06-2012

The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?
Cooper D, Iqbal AJ, Gittens BR, Cervone C and Perretti M
Ann N Y Acad Sci vol. 1253, 181-192.  
01-04-2012

Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes.
Nadkarni S, Cooper D, Brancaleone V, Bena S and Perretti M
Arterioscler Thromb Vasc Biol vol. 31 (11), 2749-2759.  
01-11-2011

Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo.
Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R, Perretti M and Cirino G
J Pharmacol Exp Ther vol. 337 (3), 830-837.  
01-06-2011

Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect.
Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Perretti M and Cooper D
Am J Pathol vol. 178 (3), 1201-1209.  
01-03-2011

Human RCAN3 gene expression and cell growth in endothelial cells
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D and Perretti M
Int J Mol Med vol. 26 (6), 913-918.  
01-12-2010

Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature.
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M and D'Acquisto F
Blood vol. 116 (20), 4288-4296.  
18-11-2010

Human RCAN3 gene expression and cell growth in endothelial cells.
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D and Perretti M
International Journal of Molecular Medicine, Spandidos Publications vol. 26 (6), 913-918.  
21-10-2010

Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization.
Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M and Flower RJ
Arterioscler Thromb Vasc Biol vol. 30 (9), 1718-1724.  
01-09-2010

Cell Adhesion Molecules
Ayoub SS, Norling LV, Leoni G, Cooper D and Perretti M
In Fundamentals of Inflammation, Cambridge University Press (Cup) 208-216.  
26-04-2010

A role for Galectin-9 in neutrophil trafficking
Cooper D, Iqbal AJ, Niki T, Hirashima M and Perretti M
Faseb Journal vol. 24 
01-04-2010

Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands
Hunter C, Kadakia TB, Cooper D, Perretti M, Schwartz RC and Brown SB
Thescientificworldjournal vol. 10, 1580-1596.  
01-01-2010

Human RCAN3 gene expression and cell growth in endothelial cells
Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D and Perretti M
International Journal of Molecular Medicine vol. 26 (6), 913-918.  
01-01-2010

Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate.
Cooper D, Ilarregui JM, Pesoa SA, Croci DO, Perretti M and Rabinovich GA
199-244.  
01-01-2010

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M and Serhan CN
Nature vol. 461 (7268), 1287-U125.  
29-10-2009

Endogenous galectins and the control of the host inflammatory response.
Norling LV, Perretti M and Cooper D
J Endocrinol vol. 201 (2), 169-184.  
01-05-2009

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles
Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY and Perretti M
Blood vol. 112 (6), 2512-2519.  
15-09-2008

Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow
Cooper D, Norling LV and Perretti M
J Leukocyte Biol vol. 83 (6), 1459-1466.  
01-06-2008

Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking
Norling LV, Sampaio ALF, Cooper D and Perretti M
Faseb J vol. 22 (3), 682-690.  
01-03-2008

Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.
Urquhart P, Rosignoli G, Cooper D, Motterlini R and Perretti M
J Pharmacol Exp Ther vol. 321 (2), 656-662.  
01-05-2007

Antiflammin-2 activates the human formyl-peptide receptor like 1.
Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E and Perretti M
Scientificworldjournal vol. 6, 1375-1384.  
25-10-2006

Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement
Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D and Perretti M
Blood vol. 107 (5), 2123-2130.  
01-03-2006

Angiotensin II type I receptors and the intestinal microvascular dysfunction induced by ischemia and reperfusion
COOPER D, Stokes KY, Wood KC, Russell J, Granger DN and Petnehazy T
Am J Physiol Gastrointest Liver Physiol vol. 290 (6), G1203-G1210.  
01-01-2006

Inflammation-induced modulation of cellular galectin-1 and –3 expression in a model of rat peritonitis
Perretti M, COOPER D, Gil CD, Oliani SM and Rosignoli G
Inflammation Research vol. 55 (3), 99-107.  
01-01-2006

Platelet-vessel wall interactions in the microcirculation
COOPER D, Granger DN and Tailor A
Microcirculation vol. 12 (3), 275-285.  
01-01-2005

15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation.
Paul-Clark MJ, Van Cao T, Moradi-Bidhendi N, Cooper D and Gilroy DW
J Exp Med vol. 200 (1), 69-78.  
05-07-2004

Leukocyte dependence of platelet adhesion in postcapillary venules
COOPER D, Granger DN, Williams M and Chitman KC
Ajp Heart and Circulatory Physiology vol. 286 (5), H1895-H1900.  
01-05-2004

Platelet-leukocyte-endothelial cell interactions following midline cerebral artery occlusion and reperfusion
Ishikawa M, Cooper D, Arumugam TV, Zhang JH, Nanda A and Granger DN
Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group vol. 24 (8), 907-915.  
01-01-2004

Time-dependent platelet-vessel wall interactions induced by intestinal ischemia-reperfusion
COOPER D, Williams M, Granger DN and Chitman KC
Am J Physiol Gastrointest Liver Physiol vol. 284 (6), G1027-G1033.  
01-06-2003

Molecular determinants of the prothrombogenic and inflammatory phenotype assumed by the postischemic cerebral microcirculation
COOPER D, Ishikawa M, Russell J, Zhang JH, Granger DN, Nanda A and Salter JW
Stroke vol. 34, 1777-1782.  
01-01-2003

Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules
COOPER D, Granger DN, McCord JM, Cerwinka WH, Krieglstein CF and Ross CR
Am J Physiol vol. 284, H535-H541.  
01-01-2003

Oxidative stress promotes blood cell-endothelial cell interactions in the microcirculation
COOPER D, Granger DN, Stokes KY and Tailor A
Cardiovasc Toxicol vol. 2, 165-180.  
01-01-2002

Hypercholesterolemia promotes inflammation and microvascular dysfunction: role of nitric oxide and superoxide
COOPER D, Stokes KY, Granger DN and Tailor A
Free Radic Biol Med vol. 33 (8), 1026-1036.  
01-01-2002

Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules
COOPER D, Granger DN, Feelisch M, Cernwinka WH and Krieglstein CF
Am J Physiol vol. 282, H1111-H1117.  
01-01-2002

Low venular shear rates promote leukocyte dependent recruitment of adherent platelets
COOPER D, Granger DN, Stokes KY, Tailor A and Russell JM
Am J Physiol vol. 284, G123-G129.  
01-01-2002

Rapid reconstitution of Epstein-Barr virus-specific T lymphocytes following allogeneic stem cell transplantation.
Marshall NA, Howe JG, Formica R, Krause D, Wagner JE, Berliner N, Crouch J, Pilip I, Cooper D, Blazar BR, Seropian S and Pamer EG
Blood, American Society of Hematology vol. 96 (8), 2814-2821.  
15-10-2000

The Identification of Endothelial Cell Autoantigens
Yazici ZA, Behrendt M, Cooper D, Goodfield M, Partridge L and Lindsey NJ
Journal of Autoimmunity, Elsevier vol. 15 (1), 41-49.  
01-08-2000