Prof Daniel Pennington
Professor of Molecular Biology and Centre Lead for Immunobiology
Centre for Immunobiology, Blizard Institute, School of Medicine
Queen Mary University of London
Queen Mary University of London
Research
Immunology, T cells
Interests
Expertise: my lab runs several thymic organ culture models, e.g. using the stromal OP9-DL1 cell line, hanging drop thymic organ culture, and standard organ cultures. We are interested in exploring the use of the Emulate Centre.Publications
2024

Gelmetti M, Tomas I, Ragazzini R, Cautela M, Campinoti S, Torre M, Watt FM, Bonfanti P, Pennington D and Sequeira I
Journal of Investigative Dermatology, Elsevier vol. 144 (12)
01-12-2024

Wiesheu R, Edwards SC, Hedley A, Hall H, Tosolini M, Fares da Silva MGF, Sumaria N, Castenmiller SM, Wardak L, Optaczy Y, Lynn A, Hill DG, Hayes AJ, Hay J, Kilbey A, Shaw R, Whyte D, Walsh PJ, Michie AM, Graham GJ, Manoharan A, Halsey C, Blyth K, Wolkers MC, Miller C, Pennington DJ, Jones GW, Fournie J-J, Bekiaris V and Coffelt SB
The Embo Journal, Springer Nature vol. 43 (14), 2878-2907.
30-05-2024

Sumaria N, Fiala GJ, Inácio D, Curado-Avelar M, Cachucho A, Pinheiro R, Wiesheu R, Kimura S, Courtois L, Blankenhaus B, Darrigues J, Suske T, Almeida ARM, Minguet S, Asnafi V, Lhermitte L, Mullighan CG, Coffelt SB, Moriggl R, Barata JT, Pennington DJ and Silva-Santos B
Nature Immunology, Springer Nature vol. 25 (7), 1207-1217.
27-05-2024

Hirani P, McDermott J, Rajeeve V, Cutillas PR, Jones JL, Pennington DJ, Wight TN, Santamaria S, Alonge KM and Pearce OMT
Cancer Research Communications, American Association For Cancer Research (Aacr) vol. 4 (4), 970-985.
03-04-2024
2023

Murtough S, Babu D, Webb CM, Picard HLD, McGinty LA, Chao-Chu J, Pink R, Silver AR, Smart HL, Field JK, Woodland P, Risk JM, Blaydon DC, Pennington DJ and Kelsell DP
Gastro Hep Advances, Elsevier vol. 3 (3), 385-395.
26-12-2023

Hindle S, Taggart E, Blowes L, Pennington D, Singh B, Caley M and Connelly J
Journal of Investigative Dermatology, Elsevier vol. 143 (5)
01-05-2023

Mann BT, Sanz M, Ryan P, Bosque A, Pennington D, Hackstein H and Soriano-Sarabia N
The Journal of Immunology, The American Association of Immunologists vol. 210 (1_Supplement), 167.15-167.15.
01-05-2023

Hirani P, Alonge KM, Pennington DJ, Cutillas PR, Wight TN and Pearce OM
Cancer Research, American Association For Cancer Research (Aacr) vol. 83 (7_Supplement), 5841-5841.
04-04-2023

Sanz M, Mann BT, Ryan PL, Bosque A, Pennington DJ, Hackstein H and Soriano-Sarabia N
Frontiers in Immunology, Frontiers vol. 14
31-03-2023
2022

Murtough S, Ramos Del Caño L, Delaney P, Webb C, Colom B, Jones P, Blaydon D, Kelsell D, Babu D and Pennington D
, Morressier
22-09-2022

Anene CA, Taggart E, Harwood CA, Pennington DJ and Wang J
Frontiers in Genetics, Frontiers vol. 13
01-04-2022
2021

Pennington D, Sumaria N and Martin S
Science Signaling, American Association For The Advancement of Science
20-07-2021

Ng KE, Delaney PJ, Thenet D, Murtough S, Webb CM, Zaman N, Tsisanova E, Mastroianni G, Walker SLM, Westaby JD, Pennington DJ, Pink R, Kelsell DP and Tinker A
Cell and Tissue Research, Springer Nature vol. 386 (1), 79-98.
08-07-2021

Park JE, JebaMercy G, Pazhanchamy K, Guo X, Ngan SC, Liou KCK, Lynn SE, Ng SS, Meng W, Lim SC, Leow MK-S, Richards AM, Pennington DJ, de Kleijn DPV, Sorokin V, Ho HH, McCarthy NE and Sze SK
Atherosclerosis, Elsevier vol. 324, 58-68.
25-03-2021

Pennington D, Lynch L, Silva-Santos B, Lopes N, McIntyre C, Martin S, Sumaria N and Raverdeau M
Nature Immunology, Nature Research, 179-192.
18-01-2021
2020

Galson JD, Schaetzle S, Bashford-Rogers RJM, Raybould MIJ, Kovaltsuk A, Kilpatrick GJ, Minter R, Finch DK, Dias J, James LK, Thomas G, Lee W-YJ, Betley J, Cavlan O, Leech A, Deane CM, Seoane J, Caldas C, Pennington DJ, Pfeffer P and Osbourn J
Frontiers in Immunology, Frontiers vol. 11
15-12-2020

Clohosey ML, Mann BT, Ryan PL, Apanasovich TV, Maggirwar SB, Pennington DJ and Soriano-Sarabia N
Cells, Mdpi vol. 9 (12)
01-12-2020

Chao-Chu J, Murtough S, Zaman N, Pennington DJ, Blaydon DC and Kelsell DP
Journal of Investigative Dermatology, Elsevier vol. 141 (4), 722-726.
17-10-2020

Galson JD, Schaetzle S, Bashford-Rogers RJM, Raybould MIJ, Kovaltsuk A, Kilpatrick GJ, Minter R, Finch DK, Dias J, James L, Thomas G, Lee W-YJ, Betley J, Cavlan O, Leech A, Deane CM, Seoane J, Caldas C, Pennington D, Pfeffer P and Osbourn J
, Cold Spring Harbor Laboratory
20-05-2020
2019

Edelblum K, Gustafsson K, Pennington DJ, Willcox BE and Ribot JC
Frontiers in Immunology, Frontiers vol. 10
25-10-2019

Webb C, Murtough S, Chikh A, Picard HLD, Wang J, Pink R, Risk JM, Fitzgerald RC, Pennington DJ and Kelsell DP
Journal of Investigative Dermatology, Elsevier vol. 139 (5)
01-05-2019

Sumaria N, Martin S and Pennington DJ
Immunology, Wiley vol. 156 (4), 299-304.
21-01-2019
2017

Grandjean CL, Sumaria N, Martin S and Pennington DJ
Scientific Reports, Springer Nature vol. 7 (1)
06-09-2017

CABRERA CP, MANSON J, SHEPHERD JM, TORRANCE HD, WATSON D, LONGHI MP, HOTI M, PATEL MB, O'DWYER M, NOURSHARGH S, PENNINGTON DJ, BARNES MR and BROHI K
Plos Medicine, Public Library of Science (Plos)
17-07-2017

Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB, O'Dwyer M, Nourshargh S, Pennington DJ, Barnes MR and Brohi K
Plos Med vol. 14 (7)
01-07-2017

Sumaria N, Grandjean CL, Silva-Santos B and Pennington DJ
Cell Rep, Cell Press vol. 19 (12), 2469-2476.
20-06-2017

Muñoz-Ruiz M, Sumaria N, Pennington DJ and Silva-Santos B
Trends in Immunology, Elsevier vol. 38 (5), 336-344.
09-03-2017

Fechter K, Dorronsoro A, Jakobsson E, Ferrin I, Lang V, Sepulveda P, Pennington DJ and Trigueros C
Plos One, Public Library of Science vol. 12 (1), e0169362-e0169362.
11-01-2017
2016

Ryan PL, Sumaria N, Holland CJ, Bradford CM, Izotova N, Grandjean CL, Jawad AS, Bergmeier LA and PENNINGTON DJ
Proceedings of The National Academy of Sciences, National Academy of Sciences vol. 113 (50), 14378-14383.
28-11-2016

Manson J, Cole E, De’Ath HD, Vulliamy P, Meier U, Pennington D and Brohi K
Critical Care vol. 20 (1)
07-06-2016

Muñoz-Ruiz M, Ribot JC, Grosso AR, Gonçalves-Sousa N, Pamplona A, Pennington DJ, Regueiro JR, Fernández-Malavé E and Silva-Santos B
Nature Immunology
04-04-2016

Stoenchev KV and Pennington DJ
In Encyclopedia of Immunobiology, Elsevier 76-84.
01-01-2016
2015

Torrance H, Brohi K, Warnes G, Owen H, Hinds C, Pennington D and O'Dwyer M
Intensive Care Medicine Experimental, Springer Nature vol. 3 (Suppl 1)
01-10-2015

Rei M, Pennington DJ and Silva-Santos B
Cancer Research, American Association For Cancer Research (Aacr) vol. 75 (5), 798-802.
01-03-2015
2014

Turner MD, Nedjai B, Hurst T and Pennington DJ
Biochim Biophys Acta vol. 1843 (11), 2563-2582.
01-11-2014

Rei M, Gonçalves-Sousa N, Lança T, Thompson RG, Mensurado S, Balkwill FR, Kulbe H, Pennington DJ and Silva-Santos B
Proc Natl Acad Sci U S A vol. 111 (34), E3562-E3570.
26-08-2014

Dorronsoro A, Ferrin I, Salcedo JM, Jakobsson E, Fernández-Rueda J, Lang V, Sepulveda P, Fechter K, Pennington D and Trigueros C
Eur J Immunol vol. 44 (2), 480-488.
01-02-2014
2013

Schmolka N, Serre K, Grosso AR, Rei M, Pennington DJ, Gomes AQ and Silva-Santos B
Nat Immunol vol. 14 (10), 1093-1100.
01-10-2013

Prinz I, Silva-Santos B and Pennington DJ
Eur J Immunol vol. 43 (8), 1988-1994.
01-08-2013

Coquet JM, Ribot JC, Bąbała N, Middendorp S, van der Horst G, Xiao Y, Neves JF, Fonseca-Pereira D, Jacobs H, Pennington DJ, Silva-Santos B and Borst J
J Exp Med vol. 210 (4), 715-728.
08-04-2013
2012

Michel M-L, Pang DJ, Haque SFY, Potocnik AJ, Pennington DJ and Hayday AC
Proc Natl Acad Sci U S A vol. 109 (43), 17549-17554.
23-10-2012

Pang DJ, Neves JF, Sumaria N and Pennington DJ
Immunology vol. 136 (3), 283-290.
01-07-2012
2011

Turchinovich G and Pennington DJ
Trends Immunol vol. 32 (12), 567-573.
01-12-2011

Mahtani-Patching J, Neves JF, Pang DJ, Stoenchev KV, Aguirre-Blanco AM, Silva-Santos B and Pennington DJ
Sci Signal vol. 4 (182)
19-07-2011
2010

Cárcamo-Orive I, Gaztelumendi A, Delgado J, Tejados N, Dorronsoro A, Fernández-Rueda J, Pennington DJ and Trigueros C
J Bone Miner Res vol. 25 (10), 2115-2125.
01-10-2010

Afifi A, Raja SG, Pennington DJ and Tsang VT
Interact Cardiovasc Thorac Surg vol. 11 (3), 287-291.
01-09-2010

Sengupta N, MacFie TS, MacDonald TT, Pennington D and Silver AR
Pathol Res Pract vol. 206 (1), 1-8.
15-01-2010
2009

Ribot JC, deBarros A, Pang DJ, Neves JF, Peperzak V, Roberts SJ, Girardi M, Borst J, Hayday AC, Pennington DJ and Silva-Santos B
Nat Immunol vol. 10 (4), 427-436.
01-04-2009

McKnight A and Pennington DJ
In Encyclopedia of Life Sciences, John Wiley & Sons, Ltd: Chichester.
01-01-2009
2008

Sancho D, Mourão-Sá D, Joffre OP, Schulz O, Rogers NC, Pennington DJ, Carlyle JR and Reis e Sousa C
J Clin Invest vol. 118 (6), 2098-2110.
01-06-2008

Hunt KA, Zhernakova A, Turner G, Heap GAR, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R, Takeuchi F, McLaren WM, Holmes GKT, Howdle PD, Walters JRF, Sanders DS, Playford RJ, Trynka G, Mulder CJJ, Mearin ML, Verbeek WHM, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP and McArdle WL
Nat Genet vol. 40 (4), 395-402.
01-04-2008
2007

Hayday AC and Pennington DJ
Nat Immunol vol. 8 (2), 137-144.
01-02-2007
2006

Pennington DJ, Silva-Santos B, Silberzahn T, Escorcio-Correia M, Woodward MJ, Roberts SJ, Smith AL, Dyson PJ and Hayday AC
Nature vol. 444 (7122), 1073-1077.
21-12-2006
2005

Pennington DJ, Silva-Santos B, Correia M and Hayday AC
Immunology vol. 116, 88-88.
01-12-2005

Pennington DJ, Silva-Santos B and Hayday AC
Curr Opin Immunol vol. 17 (2), 108-115.
01-04-2005

Silva-Santos B, Pennington DJ and Hayday AC
Science vol. 307 (5711), 925-928.
11-02-2005

Pennington DJ, Vermijlen D, Wise EL, Clarke SL, Tigelaar RE and Hayday AC
Adv Immunol vol. 87, 27-59.
01-01-2005
2003

Comalada M, Xaus J, Valledor AF, López-López C, Pennington DJ and Celada A
Am J Physiol Cell Physiol vol. 285 (5), C1235-C1245.
01-11-2003

Pennington DJ, Silva-Santos B, Shires J, Theodoridis E, Pollitt C, Wise EL, Tigelaar RE, Owen MJ and Hayday AC
Nat Immunol vol. 4 (10), 991-998.
01-10-2003

Hayday AC, Pennington DJ and Giuggio VM
Semin Immunol vol. 15 (4), 201-208.
01-08-2003

Trigueros C, Hozumi K, Silva-Santos B, Bruno L, Hayday AC, Owen MJ and Pennington DJ
Eur J Immunol vol. 33 (7), 1968-1977.
01-07-2003

Aliberti J, Schulz O, Pennington DJ, Tsujimura H, Reis e Sousa C, Ozato K and Sher A
Blood vol. 101 (1), 305-310.
01-01-2003
2002

Saurin AT, Pennington DJ, Raat NJH, Latchman DS, Owen MJ and Marber MS
Cardiovasc Res vol. 55 (3), 672-680.
15-08-2002

Leask A, Abraham DJ, Finlay DR, Holmes A, Pennington D, Shi-Wen X, Chen Y, Venstrom K, Dou X, Ponticos M, Black C, Bernabeu C, Jackman JK, Findell PR and Connolly MK
Arthritis Rheum vol. 46 (7), 1857-1865.
01-07-2002

Schulz O, Pennington DJ, Hodivala-Dilke K, Febbraio M and Reis e Sousa C
J Immunol vol. 168 (12), 6057-6065.
15-06-2002

Holmes A, Shi-Wen X, Ponticos M, Rajkumar V, Pennington D, Mukerjee D, Abraham DJ and Black CM
Rheumatology vol. 41, 58-58.
01-04-2002
2001

Castrillo A, Pennington DJ, Otto F, Parker PJ, Owen MJ and Boscá L
J Exp Med vol. 194 (9), 1231-1242.
05-11-2001
2000

Saurin AT, Pennington DJ, Raat H, Owen MJ and Marber MS
Circulation vol. 102 (18), 155-155.
31-10-2000

Shi-wen X, Pennington D, Holmes A, Leask A, Bradham D, Beauchamp JR, Fonseca C, du Bois RM, Martin GR, Black CM and Abraham DJ
Exp Cell Res vol. 259 (1), 213-224.
25-08-2000

Buckland J, Pennington DJ, Bruno L and Owen MJ
European Journal of Immunology vol. 30 (3)
03-05-2000

Buckland J, Pennington DJ, Bruno L and Owen MJ
Eur J Immunol vol. 30 (1), 8-18.
01-01-2000
1999

Holmes A, Fonseca C, Pennington D, Shiwen X, Rajkumar V, Black C and Abraham D
Arthritis Rheum vol. 42 (9), S203-S203.
01-09-1999
1997

Pennington DJ, Jenkins SA, Brady HJ, Miles CG, Dzierzak EA and Abraham DJ
Genes Funct vol. 1 (5-6), 321-335.
01-12-1997
1995

Brady HJ, Abraham DJ, Pennington DJ, Miles CG, Jenkins S and Dzierzak EA
J Virol vol. 69 (12), 7622-7629.
01-12-1995

ABRAHAM D, PENNINGTON D, MILES C, JENKINS S, BRADY H and DZIERZAK E
J Cell Biochem, 200-200.
02-04-1995
1994

Brady HJ, Pennington DJ and Dzierzak EA
J Gen Virol vol. 75 ( Pt 10), 2549-2558.
01-10-1994

Brady HJ, Miles CG, Pennington DJ and Dzierzak EA
Proc Natl Acad Sci U S A vol. 91 (1), 365-369.
04-01-1994
1993

Brady HJ, Pennington DJ, Miles CG and Dzierzak EA
Embo J vol. 12 (13), 4923-4932.
15-12-1993

Brady HJ, Miles CG, Pennington DJ and Dzierzak EA
Leukemia vol. 7 Suppl 2, S61-S65.
01-08-1993

DZIERZAK EA, MILES C, PENNINGTON D and BRADY HJM
J Cell Biochem, 249-249.
29-03-1993
Grants

Adrian Martineau, Daniel Pennington and Christopher Griffiths
£3,718,611 Barts and the London Charity
01-01-2025 - 31-12-2027

Daniel Pennington
£316,680 Barts and the London Charity
15-01-2024 - 14-01-2027

Daniel Pennington
£615,373 BBSRC Biotechnology and Biological Sciences Research Council
01-02-2023 - 31-01-2026

Catherine Harwood, Jun Wang, Daniel Pennington and Irene Leigh
£531,092 Barts and the London Charity
26-09-2022 - 01-04-2024

Daniel Pennington
£43,447 Alan Turing Institute, The
01-10-2019 - 31-03-2023

Karim Brohi, Michael Barnes and Daniel Pennington
£874,564 MRC Medical Research Council
01-01-2019 - 31-12-2022

Daniel Pennington
£464,812 BBSRC Biotechnology and Biological Sciences Research Council
01-08-2018 - 30-09-2022