Mr Dillon Popat
Bsc, MRes
PhD Student
Molecular Endocrinology
William Harvey Research Institute
Research
Adrenal, GPCR, Pharmacology, Endocrinology
PhD Title
Molecular characterisation of the MC2R/MRAP complex and its antagonists for the treatment of ACTH excess in pituitary and neuroendocrine tumours
Interests
My project involves the development of novel antagonists to the hormone ACTH which acts on the adrenal gland. I want to use advanced in vitro models to recapitulate the adrenal. Using this model I will test out the antagonists and do subsequent hormone ELISA's or use advanced mass spectrometry techniques.
GPCR Biology, Adrenal biology, biosensor assays, ELISA, hormone profiling.