Dr Ezra Aksoy
PhD, MSc, BSc, FHEALecturer
The William Harvey Research Institute
Queen Mary University of London
Queen Mary University of London
Research
intestinal immunity, intestinal repair and regeneration, host-microbiome interactions, nutrient sensing pathways, phosphoinositol 3-kinase biology, inflammasome
Interests
Our group is seeking cell signalling targets as biomarkers in immune and epithelial cells in the intestine that impact immune inflammation and regeneration processes. We use in vitro and ex vivo models to test and identify new drug targets associated with process driven inflammation and immune responses.Publications
2021
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Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS, Gonzalez-Nuñez M, Austin-Williams SN, Cooper D, Vázquez-Martínez L, Fu T, De Rossi G, Golding M, Voisin M-B, Boulanger CM, Kubota Y, Muller WA, Tooze SA, Nightingale TD, Collinson L, Perretti M, Aksoy E and Nourshargh S
Immunity, Elsevier vol. 54 (9), 1989-2004.e9.
06-08-2021
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Thibault B, Ramos‐Delgado F, Pons‐Tostivint E, Therville N, Cintas C, Arcucci S, Cassant‐Sourdy S, Reyes‐Castellanos G, Tosolini M, Villard AV, Cayron C, Baer R, Bertrand‐Michel J, Pagan D, Ferreira Da Mota D, Yan H, Falcomatà C, Muscari F, Bournet B, Delord J, Aksoy E, Carrier A, Cordelier P, Saur D, Basset C and Guillermet‐Guibert J
Embo Molecular Medicine, Springer Nature vol. 13 (7)
25-05-2021
2020
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Wood TE, Aksoy E and Hachani A
Frontiers in Cellular and Infection Microbiology, Frontiers vol. 10
19-10-2020
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Ferguson MS, Chard Dunmall LS, Gangeswaran R, Marelli G, Tysome JR, Burns E, Whitehead MA, Aksoy E, Alusi G, Hiley C, Ahmed J, Vanhaesebroeck B, Lemoine NR and Wang Y
Molecular Therapy, Elsevier (Cell Press) vol. 28 (5), 1263-1275.
27-02-2020
2019
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Aksoy E
Journal of Leukocyte Biology, Oxford University Press (Oup) vol. 106 (6), 1193-1195.
17-09-2019
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Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte J-S, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P and Marot G
Cell, Elsevier vol. 177 (5), 1201-1216.e19.
25-04-2019
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Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P and Marot G
Cell vol. 178 (1), 263-263.
25-04-2019
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Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X, Norris S, Marshall JL, Clear A, Gribben J, MacDonald TT, Buckley CD, Korbonits M and Haworth O
Cell Reports, Elsevier vol. 27 (5), 1461-1471.e4.
01-04-2019
2018
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Aksoy E, Saveanu L and Manoury B
Frontiers in Immunology, Frontiers Media Sa vol. 9
15-11-2018
2015
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Simeoli R, Mattace Raso G, Lama A, Pirozzi C, Santoro A, Di Guida F, Sanges M, Aksoy E, Calignano A, D'Arienzo A and Meli R
Journal of Nutrition, Elsevier vol. 145 (6), 1202-1210.
29-04-2015
2014
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Bontems P, Aksoy E, Burette A, Segers V, Deprez C, Mascart F and Cadranel S
Helicobacter, Wiley vol. 19 (3), 157-167.
24-03-2014
2013
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Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno-Martin I, Nock G, Filloux A, Beyaert R, Flamand V and Vanhaesebroeck B
Nature Immunology, Springer Nature vol. 14 (8), 877-877.
19-07-2013
2012
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Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM, Nock G, Filloux A, Beyaert R, Flamand V and Vanhaesebroeck B
Nature Immunology, Springer Nature vol. 13 (11), 1045-1054.
30-09-2012
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AKSOY-POISTER E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM, Nock G, Filloux A, Beyaert R, Flamand V and Vanhaesebroeck B
Nat Immunol. vol. 13 (11), 1045-1054.
01-01-2012
2011
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Johnson J, Molle C, Aksoy E, Goldman M, Goriely S and Willems F
Molecular Immunology, Elsevier vol. 48 (12-13), 1484-1493.
07-05-2011
2010
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Langlet C, Springael C, Johnson J, Thomas S, Flamand V, Leitges M, Goldman M, Aksoy E and Willems F
European Journal of Immunology, Wiley vol. 40 (2), 505-515.
26-01-2010
2008
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Goriely S, Aksoy E, De Wit D, Goldman M and Willems F
In Hematology, Immunology and Infectious Disease: Neonatology Questions and Controversies 106-134.
01-01-2008
2007
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Johnson J, Albarani V, Nguyen M, Goldman M, Willems F and Aksoy E
Journal of Biological Chemistry, Elsevier vol. 282 (20), 15022-15032.
12-02-2007
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Moore F, Buonocore S, Aksoy E, Ouled-Haddou N, Goriely S, Lazarova E, Paulart F, Heirman C, Vaeremans E, Thielemans K, Goldman M and Flamand V
The Journal of Immunology, The American Association of Immunologists vol. 178 (3), 1301-1311.
01-02-2007
2006
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Aksoy E, Albarani V, Nguyen M, Laes J-F, Ruelle J-L, De Wit D, Willems F, Goldman M and Goriely S
Blood, American Society of Hematology vol. 109 (7), 2887-2893.
30-11-2006
2005
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Aksoy E, Berghe WV, Detienne S, Amraoui Z, Fitzgerald KA, Haegeman G, Goldman M and Willems F
European Journal of Immunology, Wiley vol. 35 (7), 2200-2209.
06-06-2005
2004
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Aksoy E, Zouain CS, Vanhoutte F, Fontaine J, Pavelka N, Thieblemont N, Willems F, Ricciardi-Castagnoli P, Goldman M, Capron M, Ryffel B and Trottein F
Journal of Biological Chemistry, Elsevier vol. 280 (1), 277-283.
01-11-2004
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Vosters O, Beuneu C, Nagy N, Movahedi B, Aksoy E, Salmon I, Pipeleers D, Goldman M and Verhasselt V
Diabetologia, Springer Nature vol. 47 (4), 660-668.
19-03-2004
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Aksoy E, Goldman M and Willems F
The International Journal of Biochemistry & Cell Biology, Elsevier vol. 36 (2), 183-188.
01-02-2004
2002
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Aksoy E, Amraoui Z, Goriely S, Goldman M and Willems F
European Journal of Immunology, Wiley vol. 32 (11), 3040-3049.
16-10-2002
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Tonon S, Goriely S, Aksoy E, Pradier O, Del Giudice G, Trannoy E, Willems F, Goldman M and De Wit D
European Journal of Immunology, Wiley vol. 32 (11), 3118-3125.
16-10-2002
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Ismaili J, Rennesson J, Aksoy E, Vekemans J, Vincart B, Amraoui Z, Van Laethem F, Goldman M and Dubois PM
The Journal of Immunology, The American Association of Immunologists vol. 168 (2), 926-932.
15-01-2002
2001
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Vanderheyde N, Aksoy E, Amraoui Z, Vandenabeele P, Goldman M and Willems F
The Journal of Immunology, The American Association of Immunologists vol. 167 (7), 3565-3569.
01-10-2001
2000
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Willems F, Amraoui Z, Vanderheyde N, Verhasselt V, Aksoy E, Scaffidi C, Peter ME, Krammer PH and Goldman M
Blood, American Society of Hematology vol. 95 (11), 3478-3482.
01-06-2000
Grants
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Ezra Aksoy
£11,630 Royal Society
01-04-2022 - 31-03-2025
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Ezra Aksoy
£10,000 February Foundation, The
01-08-2020 - 31-07-2021
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Ezra Aksoy
£49,704 Barts and the London Charity
16-09-2019 - 31-01-2022
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Ezra Aksoy
£156,364 EU Commission - Horizon 2020
01-05-2017 - 30-04-2019
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Ezra Aksoy
£551,150 MRC Medical Research Council
01-06-2015 - 16-06-2019
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Ezra Aksoy
£27,227 EU European Commission - Other
01-06-2015 - 14-12-2018