Preoperative activation of the renineangiotensin system and myocardial injury in noncardiac surgery: exploratory mechanistic analysis of the SPACE randomised controlled trial
Ackland G
British Journal of Anaesthesia, Elsevier 
19-12-2024

Chronic pain: a modifiable target to reduce perioperative cardiovascular morbidity
Sikandar S and Ackland GL
British Journal of Anaesthesia, Elsevier 
01-12-2024

Perioperative myocardial injury
Hughes C, Ackland G and Shelley B
Bja Education, Elsevier vol. 24 (10), 352-360.  
01-08-2024

Adenosine signalling to astrocytes coordinates brain metabolism and function
Theparambil SM, Kopach O, Braga A, Nizari S, Hosford PS, Sagi-Kiss V, Hadjihambi A, Konstantinou C, Esteras N, Gutierrez Del Arroyo A, Ackland GL, Teschemacher AG, Dale N, Eckle T, Andrikopoulos P, Rusakov DA, Kasparov S and Gourine AV
Nature, Springer Nature vol. 632 (8023), 139-146.  
03-07-2024

Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury: A Phase 2a Intervention Design Study
Thomas M, Hayes K, White P, Baumer T, Beattie C, Ramesh A, Culliford L, Ackland GL and Pickering AE
Neurocritical Care, Springer Nature vol. 41 (3), 1009-1019.  
28-06-2024

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response
Mi Y, Burnham KL, Charles PD, Heilig R, Vendrell I, Whalley J, Torrance HD, Antcliffe DB, May SM, Neville MJ, Berridge G, Hutton P, Geoghegan CG, Radhakrishnan J, Nesvizhskii AI, Yu F, Davenport EE, McKechnie S, Davies R, O’Callaghan DJP, Patel P, del Arroyo AG, Karpe F, Gordon AC, Ackland GL, Hinds CJ, Fischer R, Knight JC, Webster N and Galley H
Science Translational Medicine, American Association For The Advancement of Science (Aaas) vol. 16 (750) 
05-06-2024

The BJA Editorial Fellowship 2024: a barometer for the state of academic anaesthesiology, perioperative, pain, and critical care medicine
Vail EA and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 133 (1), 3-6.  
13-05-2024

Ward monitoring 4.0: real-time metabolic insights from continuous glucose monitoring into perioperative organ dysfunction
Janssen H, Jhanji S, Oliver NS, Ackland GL, Investigators FTG, Korbonits M, Henson S, Yeung J, Pearse R, Shelley B, Hiller L, Jacob P, Noblet J, Jefford M, del Arroyo AG, Samman A, Alharbi S, Ahuja S and Dias P
British Journal of Anaesthesia, Elsevier vol. 132 (5), 843-848.  
05-03-2024

Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin–angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial
del Arroyo AG, Patel A, Abbott TEF, Begum S, Dias P, Somanath S, Middleditch A, Cleland S, Brealey D, Pearse RM, Ackland GL, Ackland G, Martin T, Fernandez M, Seidu F, Pakats M-L, Mahr O, MacDonald N, Dos Santos F, Garcia AA, Uddin R, Begum S, Pearse R, Subhedar E, Wan Y, Shahid T, Gooneratne M, Trainer C and Griffiths B
British Journal of Anaesthesia, Elsevier vol. 132 (5), 857-866.  
09-02-2024

Transcriptional response of the heart to vagus nerve stimulation.
Kellett DO, Aziz Q, Humphries JD, Korsak A, Braga A, Del Arroyo AG, Crescente M, Tinker A, Ackland GL and Gourine AV
Physiol Genomics vol. 56 (2), 167-178.  
01-02-2024

Pathophysiological mechanisms underlying increased circulating cardiac troponin in noncardiac surgery: a narrative review
Bollen Pinto B and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 132 (4), 653-666.  
22-01-2024

Cystatin C or creatinine for pre-operative assessment of kidney function and risk of post-operative acute kidney injury: a secondary analysis of the METS cohort study
Prowle JR, Croal B, Abbott TEF, Cuthbertson BH, Wijeysundera DN, Myles PS, Shulman MA, Wallace S, Farrington C, Thompson B, Ellis M, Borg B, Kerridge RK, Douglas J, Brannan J, Pretto J, Godsall MG, Beauchamp N, Allen S, Kennedy A, Wright E, Malherbe J, Ismail H, Riedel B, Melville A, Sivakumar H, Murmane A, Kenchington K, Kirabiyik Y and Gurunathan U
Clinical Kidney Journal, Oxford University Press (Oup) vol. 17 (1) 
04-01-2024

Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study.
Polok K, Biccard BM, Chan MTV, Archbold RA, Wang CY, Sigamani A, Urrútia G, Cruz P, Srinathan SK, Szalay D, Harlock J, Tittley JG, Elias F, Jacka MJ, Malaga G, Berwanger O, Studzińska D, Górka J, Montes FR, Chow CK, Ackland GL, Dubois L, Sapsford RJ, Williams C, Cortés OL, Devereaux PJ and Szczeklik W
Polish Archives of Internal Medicine, &Quot;Medycyna Praktyczna&Quot; Spolka Jawna vol. 134 (2) 
02-01-2024

Transauricular nerve stimulation in acute ischaemic stroke requiring mechanical thrombectomy: Protocol for a phase 2A, proof-of-concept, sham-controlled randomised trial
Ackland GL, Martin T, Joseph M, Dias P, Hameed R, del Arroyo AG, Hewson R, Abbott TEF, Spooner O and Bhogal P
Plos One, Public Library of Science (Plos) vol. 18 (12) 
22-12-2023

Transcriptional response of the heart to vagus nerve stimulation.
Kellett DO, Aziz Q, Humphries JD, Korsak A, Braga A, Gutierrez Del Arroyo A, Crescente M, Tinker A, Ackland GL and Gourine AV
Physiol Genomics 
04-12-2023

ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation
Lurati Buse G, Bollen Pinto B, Abelha F, Abbott TEF, Ackland G, Afshari A, De Hert S, Fellahi JL, Giossi L, Kavsak P, Longrois D, M'Pembele R, Nucaro A, Popova E, Puelacher C, Richards T, Roth S, Sheka M, Szczeklik W, Van Waes J, Walder B and Chew MS
European Journal of Anaesthesiology vol. 40 (12), 888-927.  
01-12-2023

Discontinuation vs. continuation of renin–angiotensin system inhibition before non-cardiac surgery: the SPACE trial
Ackland G
European Heart Journal, Oxford University Press 
07-11-2023

Heart rate recovery after orthostatic challenge and cardiopulmonary exercise testing in older individuals: prospective multicentre observational cohort study
James A, Bruce D, Tetlow N, Patel ABU, Black E, Whitehead N, Ratcliff A, Humphreys AJ, MacDonald N, McDonnell G, Raobaikady R, Thirugnanasambanthar J, Ravindran JI, Minto G, Abbott TEF, Jhanji S, Milliken D and Ackland GL
Bja Open, Elsevier vol. 8 
03-11-2023

One-year Outcomes after Discharge from Noncardiac Surgery and Association between Predischarge Complications and Death after Discharge: Analysis of the VISION Prospective Cohort Study
Roshanov PS, Chan MTV, Borges FK, Conen D, Wang CY, Xavier D, Berwanger O, Marcucci M, Sessler DI, Szczeklik W, Spence J, Alonso-Coello P, Fernández C, Pearse RM, Malaga G, Garg AX, Srinathan SK, Jacka MJ, Tandon V, McGillion M, Popova E, Sigamani A, Abraham V, Biccard BM, Villar JC, Chow CK, Polanczyk CA, Tiboni M, Whitlock R and Ackland GL
Anesthesiology, Wolters Kluwer vol. 140 (1), 8-24.  
15-09-2023

Study protocol for IMPRoVE: a multicentre prospective observational cohort study of the incidence, impact and mechanisms of perioperative right ventricular dysfunction in non-cardiac surgery
Keast T, McErlane J, Kearns R, McKinlay S, Raju I, Watson M, Robertson KE, Berry C, Greenlaw N, Ackland G, McCall P and Shelley B
Bmj Open, Bmj vol. 13 (9) 
01-09-2023

Immediate and sustained increases in the activity of vagal preganglionic neurons during exercise and after exercise training
Korsak A, Kellett DO, Aziz Q, Anderson C, D’Souza A, Tinker A, Ackland GL and Gourine AV
Cardiovascular Research, Oxford University Press (Oup) vol. 119 (13), 2329-2341.  
30-07-2023

Human neutrophils communicate remotely via calcium-dependent glutamate-induced glutamate release
Kopach O, Sylantyev S, Bard L, Michaluk P, Heller JP, del Arroyo AG, Ackland GL, Gourine AV and Rusakov DA
Iscience, Elsevier vol. 26 (7) 
28-06-2023

Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury (EBB-TBI): Protocol for a Phase 2a Intervention Design Study
Thomas M, Hayes K, White P, Ramesh A, Culliford L, Ackland G and Pickering A
Neurocritical Care, Springer Nature vol. 40 (2), 795-806.  
12-06-2023

Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery
Edwards MR, Forbes G, Walker N, Morton DG, Mythen MG, Murray D, Anderson I, Mihaylova B, Thomson A, Taylor M, Hollyman M, Phillips R, Young K, Kahan BC, Pearse RM and Grocott MPW
Trials, Springer Nature vol. 24 (1) 
06-05-2023

Effect of transauricular nerve stimulation on perioperative pain: a single-blind, analyser-masked, randomised controlled trial
Patel ABU, Bibawy PPWM, Althonayan JIM, Majeed Z, Gan WL, Abbott TEF and Ackland GL
British Journal of Anaesthesia, Elsevier 
22-02-2023

Arterial cannulation with ultrasound: clinical trial protocol for a randomised controlled trial comparing handheld ultrasound versus palpation technique for radial artery cannulation
Lan-Pak-Kee V, Ackland GL, Egan TC, Abbott TE, Elsheikh F, Investigators TACWU, Barrett S, Gooneratne M, May SM, Mitchard M, O'Neill T, Overend J, Abbott TE, Pang C-L, Radhakrishnan A, Reynolds T, Vadher M, Verma P, Wikner M and Wood A
Bja Open, Elsevier vol. 4 
01-12-2022

Sex-specific differences in cardiac function, inflammation and injury during early polymicrobial sepsis
Walker SLM, Muthoo C, Sanchez J, Del Arroyo AG and Ackland GL
Intensive Care Medicine Experimental, Springer Nature vol. 10 (1) 
20-06-2022

Trans-auricular vagus nerve stimulation to reduce perioperative pain and morbidity: protocol for a single-blind analyser-masked randomised controlled trial
Patel ABU, Bibawy PPWM, Majeed Z, Gan WL and Ackland GL
Bja Open, Elsevier vol. 2 
01-06-2022

IL-1ra polymorphisms and risk of epidural-related maternal fever (EPIFEVER-2): study protocol for a multicentre, observational mechanistic cohort study
Ali A, Weber V, Thompson SJ, Abbott TEF, Harmston R, David AL, Ackland GL and investigators FTE
International Journal of Obstetric Anesthesia, Elsevier vol. 50 
18-03-2022

Hypotension as a marker or mediator of perioperative organ injury: a review
Ackland G and ABBOTT T
British Journal of Anaesthesia, Elsevier 
09-02-2022

Reply to: Monitors are not a treatment.
Abbott TEF and Ackland GL
Eur J Anaesthesiol vol. 39 (2), 180-180.  
01-02-2022

Metformin and mortality after surgery: a systematic review and meta-analysis
Jones TF, Iakovou D, Makariou N, Fowler AJ and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 128 (4), e277-e279.  
26-01-2022

2 The Inflammatory Response to Surgery
Ackland GL, Walker SLM and Jones TF
In Perioperative Medicine, Elsevier 9-15.  
01-01-2022

Interleukin-1 receptor antagonist and risk of caesarean delivery after onset of labour: a Mendelian randomisation analysis.
Ackland G, Van Duijvenboden S, ABBOTT T, Gutierrez Del Arroyo A, Wilson M and David A
British Journal of Anaesthesia, Elsevier 
18-11-2021

The potential for autonomic neuromodulation to reduce perioperative complications and pain: a systematic review and meta-analysis
Patel ABU, Weber V, Gourine AV and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 128 (1), 135-149.  
18-11-2021

Immunomodulation of innate immunity by brachial plexus blockade: a crossover study
May SM, Chiang E, Reyes A, Martir G, Patel A, Karmali S, Patel S, West S, del Arroyo AG, Gourine AV and Ackland GL
British Journal of Anaesthesia vol. 127 (3), e116-e118.  
17-11-2021

Neuromodulation of innate immunity by remote ischaemic conditioning in humans: Experimental cross-over study
May SM, Chiang E, Reyes A, Martir G, Patel A, Karmali S, Patel S, West S, del Arroyo AG, Gourine AV and Ackland GL
Brain Behavior & Immunity - Health, Elsevier vol. 16 
15-07-2021

Proteomic signatures for perioperative oxygen delivery in skin after major elective surgery: mechanistic sub-study of a randomised controlled trial
Heywood WE, Bliss E, Bahelil F, Cyrus T, Crescente M, Jones T, Iqbal S, Paredes LG, Toner AJ, Del Arroyo AG, O'Toole EA, Mills K and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 127 (4), 511-520.  
06-07-2021

Preprints in perioperative medicine: immediacy for the greater good
Pearse RM, Ackland GL, Asai T and Hemmings HC
British Journal of Anaesthesia, Elsevier vol. 126 (5), 915-918.  
29-03-2021

Preoperative lymphopaenia, mortality, and morbidity after elective surgery: systematic review and meta-analysis
Schroth J, Weber V, Jones TF, Del Arroyo AG, Henson SM and Ackland GL
British Journal of Anaesthesia, Elsevier 
29-03-2021

International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020)
Farmer AD, Strzelczyk A, Finisguerra A, Gourine AV, Gharabaghi A, Hasan A, Burger AM, Jaramillo AM, Mertens A, Majid A, Verkuil B, Badran BW, Ventura-Bort C, Gaul C, Beste C, Warren CM, Quintana DS, Hämmerer D, Freri E, Frangos E, Tobaldini E, Kaniusas E, Rosenow F, Capone F, Panetsos F, Ackland GL, Kaithwas G, O'Leary GH, Genheimer H and Jacobs HIL
Frontiers in Human Neuroscience, Frontiers vol. 14 
23-03-2021

Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study
Abbott TEF, Howell S, Pearse RM and Ackland GL
European Journal of Anaesthesiology vol. 38 (5), 468-476.  
12-01-2021

Reducing the dose of neuromuscular blocking agents with adjuncts: a systematic review and meta-analysis
Weber V, Abbott TEF and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 126 (3), 608-621.  
17-11-2020

Selective optogenetic stimulation of efferent fibers in the vagus nerve of a large mammal
Booth LC, Yao ST, Korsak A, Farmer DGS, Hood SG, McCormick D, Boesley Q, Connelly AA, McDougall SJ, Korim WS, Guild S-J, Mastitskaya S, Le P, Teschemacher AG, Kasparov S, Ackland GL, Malpas SC, McAllen RM, Allen AM, May CN and Gourine AV
Brain Stimulation, Elsevier vol. 14 (1), 88-96.  
17-11-2020

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers
Shrimpton AJ, Walker SLM and Ackland GL
Bja Education, Elsevier vol. 20 (11), 362-367.  
27-08-2020

MicroRNA signatures of perioperative myocardial injury after elective noncardiac surgery: a prospective observational mechanistic cohort study
May S, Abbott TEF, Gutierrez Del Arroyo A, Reyes A, Martir G, Stephens RCM, Brealey D, Cuthbertson B, Wijeysundera D, Pearse R and Ackland G
British Journal of Anaesthesia, Elsevier vol. 125 (5), 661-671.  
25-07-2020

MicroRNA signatures of perioperative myocardial injury after elective noncardiac surgery: a prospective observational mechanistic cohort study
May SM, Abbott TEF, Del Arroyo AG, Reyes A, Martir G, Stephens RCM, Brealey D, Cuthbertson BH, Wijeysundera DN, Pearse RM and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 125 (5), 661-671.  
24-07-2020

A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study
Riedel B, Li MHG, Lee CHA, Ismail H, Cuthbertson BH, Wijeysundera DN, Ho KM, Wallace S, Thompson B, Ellis M, Borg B, Kerridge RK, Douglas J, Brannan J, Pretto J, Godsall MG, Beauchamp N, Allen S, Kennedy A, Wright E, Malherbe J, Melville A, Sivakumar H, Murmane A, Kenchington K, Kirabiyik Y, Gurunathan U and Stonell C
British Journal of Anaesthesia 
18-07-2020

Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure
Machhada A, Hosford PS, Dyson A, Ackland GL, Mastitskaya S and Gourine AV
Jacc Basic to Translational Science 
01-07-2020

Prospective observational study of postoperative infection and outcomes after noncardiac surgery: analysis of prospective data from the VISION cohort
Wan YI, Patel A, ABBOTT TEF, Achary C, Macdonald N, Duceppe E, Sessler DI, Szczeklik W, Ackland GL, Devereaux PJ and Pearse RM
British Journal of Anaesthesia, Elsevier Bv 
30-05-2020

The effect of general anaesthetics on brain lactate release
Hadjihambi A, Karagiannis A, Theparambil SM, Ackland GL and Gourine AV
European Journal of Pharmacology, Elsevier vol. 881 
19-05-2020

Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study
Ackland GL, ABBOTT T, Jones TF, Leuwer M, Pearse R, Niebrzegowska E, Wragg A, Archbold A, Kam E, Everingham K, Bodger P, Creary T, Bloom B, Carter A, MacDonald N, Shah N, Mrozek K, Richardson A, Fowler A, Rob Z, Ackland G, Stephens R, Reyes A, Paredes LG, Sultan P, Cain D, Whittle J, Edwards M, Woldman S and Gutierrez del Arroyo A
British Journal of Anaesthesia, Elsevier 
05-03-2020

Preoperative n-terminal pro-b-type natriuretic peptide and cardiovascular events after noncardiac surgery: A cohort study
Duceppe E, Patel A, Chan MTV, Berwanger O, Ackland G, Kavsak PA, Rodseth R, Biccard B, Chow CK, Borges FK, Guyatt G, Pearse R, Sessler DI, Heels-Ansdell D, Kurz A, Wang CY, Szczeklik W, Srinathan S, Garg AX, Pettit S, Sloan EN, Januzzi JL, McQueen M, Buse GL, Mills NL, Zhang L, Sapsford R, Paré G, Walsh M and Whitlock R
Annals of Internal Medicine vol. 172 (2), 96-104.  
21-01-2020

40 What happens to the autonomic nervous system in critical illness?
Ackland GL
In Evidence-Based Practice of Critical Care, Elsevier 279-284.e1.  
01-01-2020

Integration of the Duke Activity Status Index into Preoperative Risk Evaluation: A Multicentre Prospective Cohort Study
Wijeysundera D, Beattie WS, Hillis G, ABBOTT T, Shulman M, Ackland G, Mazer D, Myles P, Pearse R and Cuthbertson B
British Journal of Anaesthesia, Elsevier 
19-12-2019

Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA, Cuthbertson BH, Wijeysundera D and Pearse RM
Plos One, Public Library of Science (Plos) vol. 14 (12) 
05-12-2019

Inotropes and Vasopressors for Shock
Patel ABU and Ackland GL
Deckermed Transitional Year Weekly Curriculum™, Decker 
06-11-2019

Elevated heart rate after non-cardiac surgery: post-hoc analysis of a prospective observational cohort study
Patel ABU, May SM, Reyes A, Martir G, Brealey D, Stephens RCM, Abbott TEF and Ackland GL
, Cold Spring Harbor Laboratory 
02-11-2019

Salvaging remote ischaemic preconditioning as a therapy for perioperative acute kidney injury
Zarbock A, Kellum JA, Gourine AV and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 124 (1), 8-12.  
17-10-2019

P3509Leukocyte derived tumour necrosis factor modulates cardiac function in health and disease
Walker S, Del Arroyo AG, Sanchez J and Ackland GL
European Heart Journal, Oxford University Press (Oup) vol. 40 (Supplement_1) 
01-10-2019

Redefining the perioperative stress response: a narrative review
Manou-Stathopoulou V, Korbonits M and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 123 (5), 570-583.  
20-09-2019

Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data
Stephens TJ, Peden CJ, Haines R, Grocott MPW, Murray D, Cromwell D, Johnston C, Hare S, Lourtie J, Drake S, Martin GP and Pearse RM
Bmj Quality and Safety, Bmj Publishing Group 
12-09-2019

Acquired loss of cardiac vagal activity is associated with myocardial injury in patients undergoing noncardiac surgery: prospective observational mechanistic cohort study
May SM, Reyes A, Martir G, Reynolds J, Paredes LG, Karmali S, Stephens RCM, Brealey D and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 123 (6), 758-767.  
03-09-2019

A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT
Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Everingham K, Kocman D, Lourtie J, Drake S, Girling A, Lilford R, Rivett K, Wells D, Mahajan R, Holt P, Yang F, Walker S, Richardson G, Kerry S, Anderson I, Murray D, Cromwell D, Phull M, Grocott MP, Bion J and Pearse RM
Health and Social Care Delivery Research, National Institute For Health and Care Research vol. 7 (32), 1-96.  
01-09-2019

NMDA receptor modulation of glutamate release in activated neutrophils
del Arroyo AG, Hadjihambi A, Sanchez J, Turovsky E, Kasymov V, Cain D, Nightingale TD, Lambden S, Grant SGN, Gourine AV and Ackland GL
Ebiomedicine, Elsevier Bv 
01-08-2019

Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA, Cuthbertson BH, Wijeysundera D and Pearse RM
Plos One vol. 14 (8) 
01-08-2019

Association between complications and death within 30 days after noncardiac surgery.
The Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators
Canadian Medical Association Journal, Joule Inc. vol. 191 (30), E830-E837.  
28-07-2019

Type 2 diabetes is associated with the accumulation of senescent T cells
Lau EYM, Carroll EC, Callender LA, Hood GA, Berryman V, Pattrick M, Finer S, Hitman GA, Ackland GL and Henson SM
Clinical & Experimental Immunology, Wiley 
28-06-2019

Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study
Bartoszko J, Thorpe KE, Laupacis A, Wijeysundera DN, Myles PS, Shulman MA, Wallace S, Farrington C, Thompson B, Ellis M, Borg B, Kerridge RK, Douglas J, Brannan J, Pretto J, Godsall MG, Beauchamp N, Allen S, Kennedy A, Wright E, Malherbe J, Ismail H, Riedel B, Melville A, Sivakumar H, Murmane A, Kenchington K, Kirabiyik Y, Gurunathan U and Stonell C
British Journal of Anaesthesia 
19-06-2019

Electroencephalography-guided anaesthetic administration does not impact postoperative delirium among older adults undergoing major surgery: an independent discussion of the ENGAGES trial
Ackland GL and Pryor KO
British Journal of Anaesthesia, Elsevier vol. 123 (2), 112-117.  
10-05-2019

Chronotropic incompetence and myocardial injury after non-cardiac surgery: planned secondary analysis of a prospective observational international cohort study
ABBOTT TEF, PEARSE RM, beattie S, Phull M, Beilstein C, Raj A, Grocott M, Cuthbertson B, Wijeysundera D and ACKLAND GL
Bja: British Journal of Anaesthesia, Elsevier vol. 123 (1), 17-26.  
04-05-2019

Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery: A stepped-wedge cluster randomised trial
PEARSE RM, Peden C, STEPHENS T, Martin G, KAHAN B, Thomson A, Rivett K, Wells D, Richardson G, KERRY SM and Bion J
Lancet, Elsevier 
25-04-2019

Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery
Sessler DI, Bloomstone JA, Aronson S, Berry C, Gan TJ, Kellum JA, Plumb J, Mythen MG, Grocott MPW, Edwards MR, Miller TE, workgroup TPQI, chairs P, Grocott MP, group P, Ackland GL, Brudney CS, Cecconi M, Ince C, Irwin MG, Lacey J, Pinsky MR, group PBP, Sanders R, Hughes F, Bader A and Thompson A
British Journal of Anaesthesia, Elsevier vol. 122 (5), 563-574.  
27-02-2019

Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine
Ackland GL, Brudney CS, Cecconi M, Ince C, Irwin MG, Lacey J, Pinsky MR, Grocott MP, Mythen MG, Edwards MR, Miller TE, workgroup PQI, chairs P, group P, Ackland GL, group PBP, Sanders R, Hughes F, Bader A, Thompson A, Hoeft A, Williams D and Shaw AD
British Journal of Anaesthesia, Elsevier vol. 122 (5), 542-551.  
14-02-2019

Intra-operative heart rate and postoperative outcomes – rowing against the tide?
Pinto BB, Filipovic M and Ackland G
European Journal of Anaesthesiology, Wolters Kluwer vol. 36 (2), 90-92.  
01-02-2019

Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery
McEvoy MD, Gupta R, Koepke EJ, Feldheiser A, Michard F, Levett D, Thacker JKM, Hamilton M, Grocott MPW, Mythen MG, Miller TE, Edwards MR, Ackland GL, Brudney CS, Cecconi M, Ince C, Irwin MG, Lacey J, Pinsky MR, Sanders R, Hughes F, Bader A, Thompson A, Hoeft A, Williams D, Shaw AD, Sessler DI, Aronson S, Berry C and Gan TJ
British Journal of Anaesthesia 
03-01-2019

Cardiac Vagus and Exercise.
Gourine AV and Ackland GL
Physiology (Bethesda) vol. 34 (1), 71-80.  
01-01-2019

Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery
ACKLAND GL
British Journal of Anaesthesia, Elsevier 
01-01-2019

Autonomic Dysfunction in Shock
Ackland GL
In Hemodynamic Monitoring, Springer Nature 71-80.  
01-01-2019

Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study
Abbott TEF, Pearse RM, Cuthbertson BH, Wijeysundera DN and Ackland GL
British Journal of Anaesthesia 
01-01-2019

Role of leucocyte caspase-1 activity in epidural-related maternal fever: a single-centre, observational, mechanistic cohort study
del Arroyo AG, Sanchez J, Patel S, Phillips S, Reyes A, Cubillos C, Fernando R, David AL, Reeve A, Sodha S, Ciechanowicz S, Olearo E, Dick J, Stewart A, Sultan P and Ackland GL
British Journal of Anaesthesia 
29-10-2018

Perioperative medicine and UK plc
Ackland GL, Galley HF, Shelley B and Lambert DG
British Journal of Anaesthesia 
26-10-2018

Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery
Ackland GL, Abbott TEF, Cain D, Edwards MR, Sultan P, Karmali SN, Fowler AJ, Whittle JR, MacDonald NJ, Reyes A, Paredes LG, Stephens RCM, Del Arroyo AG, Woldman S, Archbold RA, Wragg A, Kam E, Ahmad T, Khan AW, Niebrzegowska E and Pearse RM
British Journal of Anaesthesia 
01-10-2018

Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery
TORRANCE H, LONGBOTTOM R, VIVIAN M, Lalabekyan B, ABBOTT TEF, ACKLAND GL, HINDS CJ, PEARSE RM and O'DWYER M
Plos One, Public Library of Science (Plos) vol. 13 (9) 
13-09-2018

MicroRNA profiles are associated with lymphocyte count after a major traumatic injury: a potential role for immunometabolism?
Jones TF, Torrance HDT, Owen HC, Brohi K, Barnes MR, Knight JC, Hinds CJ, Ackland GL and O’Dwyer MJ
British Journal of Anaesthesia, Elsevier vol. 121 (2), e23-e24.  
01-08-2018

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study
Wijeysundera D, PEARSE R, shulman M, ABBOTT TEF, Torres E, Ambosta A, Bernard C, Granton J, Thorpe K, Grocott M, Farrington C, Myles P and Cuthbertson B
Lancet, Elsevier vol. 391 (10140), 2631-2640.  
29-06-2018

Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners
WALKER S, ABBOTT TEF, Brown K, PEARSE R and ACKLAND G
Peerj, Peerj Inc. 
29-06-2018

Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost–consequence analysis
Lurati Buse G, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC, Sigamani A, Sessler DI, Berwanger O, Biccard BM, Pearse R, Urrútia G, Szczeklik RW, Garutti I, Srinathan S, Malaga G, Abraham V, Chow CK, Jacka MJ, Tiboni M, Ackland G, Macneil D, Sapsford R, Leuwer M, Le Manach Y and Devereaux PJ
Canadian Journal of Surgery vol. 61 (3), 185-194.  
01-06-2018

Serial holter recordings in non-cardiac surgery patients reveal postoperative autonomic impairment within 48 hours
May S, Karmali S, Reyes A, Paredes LG, Martir G, Stephens R, Brealey D and Ackland G
British Journal of Anaesthesia, Elsevier vol. 120 (5), e16-e17.  
01-05-2018

Arterial pulse pressure and postoperative morbidity in high-risk surgical patients.
ackland GL, ABBOTT T, Pearse RM, Karmali S, Whittle J and Minto G
British Journal of Anaesthesia, Elsevier vol. 120 (1), 94-100.  
01-01-2018

A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study
ABBOTT T, pearse RM, Archbold RA, Ahmad T, Niebrzegowska E, Wragg A, Rodseth R, Devereaux PJ and Ackland G
Anesthesia and Analgesia, Lippincott, Williams & Wilkins vol. 126 (6), 1936-1945.  
26-10-2017

Autonomic regulation of systemic inflammation in humans: a multi-center, blinded observational cohort study.
ACKLAND GL, Minto G, Clark M, Whittle J, Stephens RCM, Owen T, Prabhu P and del Arroyo AG
, Editors: Kelley K. Brain, Behavior, and Immunity, Elsevier 
11-08-2017

Heart rate variability in critical care medicine: a systematic review
Karmali SN, Sciusco A, May SM and Ackland GL
Intensive Care Medicine Experimental, Springer Nature vol. 5 (1) 
12-07-2017

Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery
ABBOTT T, pearse R, ahmad T and ackland G
British Journal of Anaesthesia, Oup vol. 119 (1), 78-86.  
28-06-2017

Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients.
ABBOTT T, Lee A, Pearse R, Ackland G and Minto G
British Journal of Anaesthesia, Oup vol. 119 (1), 87-94.  
28-06-2017

Vagal determinants of exercise capacity
Machhada A, Trapp S, Marina N, Stephens RCM, Whittle J, Lythgoe MF, Kasparov S, Ackland GL and Gourine AV
Nature Communications, Springer Nature vol. 8 (1) 
18-05-2017

Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients: A Prospective Observational Cohort Study.
Biccard BM, Scott DJA, Chan MTV, Archbold A, Wang C-Y, Sigamani A, Urrútia G, Cruz P, Srinathan SK, Szalay D, Harlock J, Tittley JG, Rapanos T, Elias F, Jacka MJ, Malaga G, Abraham V, Berwanger O, Montes FR, Heels-Ansdell DM, Hutcherson MT, Chow CK, Polanczyk CA, Szczeklik W, Ackland GL, Dubois L, Sapsford RJ, Williams C, Cortés OL and Le Mananch Y
Ann Surg 
08-05-2017

Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery.
Writing Committee for the VISION Study Investigators , Devereaux PJ, Biccard BM, Sigamani A, Xavier D, Chan MTV, Srinathan SK, Walsh M, Abraham V, Pearse R, Wang CY, Sessler DI, Kurz A, Szczeklik W, Berwanger O, Villar JC, Malaga G, Garg AX, Chow CK, Ackland G, Patel A, Borges FK, Belley-Cote EP, Duceppe E, Spence J, Tandon V, Williams C, Sapsford RJ, Polanczyk CA and Tiboni M
Jama vol. 317 (16), 1642-1651.  
25-04-2017

Acute kidney injury and mortality 1 year after major non-cardiac surgery
O'Connor ME, Hewson RW, Kirwan CJ, Ackland GL, Pearse RM and Prowle JR
British Journal of Surgery, Wiley 
20-02-2017

Postoperative goal-directed therapy and development of acute kidney injury following major elective noncardiac surgery: post-hoc analysis of POM-O randomized controlled trial
Patel A, Prowle JR, Ackland GL and Investigators P-OS
Clinical Kidney Journal, Oxford University Press (Oup) vol. 10 (3), 348-356.  
12-01-2017

Reply: Glucagon-like peptide-1 mediates cardioprotection by remote ischaemic conditioning.
Basalay M, Mastitskaya S, Mrochek A, Ackland GL, Arroyo AGD, Sanchez J, Sjoquist P-O, Pernow J, Gourine AV and Gourine A
Cardiovasc Res vol. 113 (1), 13-14.  
09-01-2017

Mechanisms of CO2/H+ Sensitivity of Astrocytes
Turovsky E, Theparambil SM, Kasymov V, Deitmer JW, del Arroyo AG, Ackland GL, Corneveaux JJ, Allen AN, Huentelman MJ, Kasparov S, Marina N and Gourine AV
Journal of Neuroscience, Society For Neuroscience vol. 36 (42), 10750-10758.  
19-10-2016

Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning
Basalay MV, Mastitskaya S, Mrochek A, Ackland GL, del Arroyo AG, Sanchez J, Sjoquist P-O, Pernow J, Gourine AV and Gourine A
Cardiovascular Research, Oxford University Press (Oup) vol. 112 (3), 669-676.  
04-10-2016

Baroreflex impairment and morbidity after major surgery
Toner A, Jenkins N and Ackland GL
, Editors: Myles PS. British Journal of Anaesthesia, Oxford University Press (Oup): Policy B - Oxford Open Option B vol. 117 (3), 324-331.  
19-08-2016

Molecular Mechanisms Linking Autonomic Dysfunction and Impaired Cardiac Contractility in Critical Illness.
Ackland GL, Whittle J, Toner A, Machhada A, Del Arroyo AG, Sciuso A, Jenkins N, Dyson A, Struthers R, Sneyd JR, Minto G, Singer M, Shah AM and Gourine AV
Crit Care Med vol. 44 (8), e614-e624.  
01-08-2016

Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study
Abbott TEF, Ackland GL, Archbold RA, Wragg A, Kam E, Ahmad T, Khan AW, Niebrzegowska E, Rodseth RN, Devereaux PJ and Pearse RM
, Editors: Hemmings HC. British Journal of Anaesthesia vol. 117 (2), 172-181.  
01-08-2016

Big Data: A Cheerleader for Translational Perioperative Medicine.
Ackland GL and Stephens RCM
Anesth Analg vol. 122 (6), 1744-1747.  
01-06-2016

Inflammation and Epidural-Related Maternal Fever
Sultan P, David AL, Fernando R and Ackland GL
Anesthesia & Analgesia vol. 122 (5), 1546-1553.  
01-05-2016

Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery.
Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Croal BL, Granton JT, Thorpe KE, Grocott MPW, Farrington C, Myles PS, Cuthbertson BH and Investigators METSS
Bmj Open vol. 6 (3), e010359-e010359.  
11-03-2016

Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease
Nelson A, Otto J, Whittle J, Stephens RCM, Martin DS, Prowle JR and Ackland GL
Open Heart, Bmj vol. 3 (1) 
01-02-2016

Astrocytes and Brain Hypoxia
Marina N, Kasymov V, Ackland GL, Kasparov S and Gourine AV
Advances in Experimental Medicine and Biology, Springer Nature vol. 903, 201-207.  
01-01-2016

Non-inferiority of retrospective data collection for assessing perioperative morbidity
Patel ABU, Reyes A and Ackland GL
Peerj, Peerj vol. 3 
01-12-2015

Association between intraoperative heart rate and postoperative myocardial injury in patients following non-cardiac surgery.
Abbott T, Ackland GL, Wragg A, Rodseth R, Archbold A and Pearse RM
Intensive Care Med Exp vol. 3 (Suppl 1), A751-A751.  
01-12-2015

Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis
Whittle J, Nelson A, Otto JM, Stephens RCM, Martin DS, Sneyd JR, Struthers R, Minto G and Ackland GL
Open Heart, Bmj vol. 2 (1) 
01-10-2015

Randomized controlled trial of vagal modulation by sham feeding in elective non-gastrointestinal (orthopaedic) surgery
Karmali S, Jenkins N, Sciusco A, John J, Haddad F, Ackland GL and Investigators P-XS
British Journal of Anaesthesia, Elsevier vol. 115 (5), 727-735.  
30-08-2015

Vagal Modulation of Atrial Fibrillation
Machhada A, Gourine AV and Ackland GL
Journal of The American College of Cardiology, Elsevier vol. 66 (8), 977-978.  
01-08-2015

Functional Oxygen Sensitivity of Astrocytes
Angelova PR, Kasymov V, Christie I, Sheikhbahaei S, Turovsky E, Marina N, Korsak A, Zwicker J, Teschemacher AG, Ackland GL, Funk GD, Kasparov S, Abramov AY and Gourine AV
Journal of Neuroscience, Society For Neuroscience vol. 35 (29), 10460-10473.  
22-07-2015

Metabolic dysfunction in lymphocytes promotes postoperative morbidity.
Edwards MR, Sultan P, del Arroyo AG, Whittle J, Karmali SN, Moonesinghe SR, Haddad FS, Mythen MG, Singer M and Ackland GL
Clinical Science, Portland Press vol. 129 (5), 423-437.  
11-06-2015

Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve
Machhada A, Ang R, Ackland GL, Ninkina N, Buchman VL, Lythgoe MF, Trapp S, Tinker A, Marina N and Gourine AV
Heart Rhythm, Elsevier vol. 12 (11), 2285-2293.  
05-06-2015

Contemporary Perioperative Management of Adult Familial Dysautonomia (Riley-Day Syndrome)
Milne A, Mon WY, Down J, Obichere A and Ackland GL
A & a Case Reports, Wolters Kluwer vol. 4 (9), 111-113.  
01-05-2015

Individualised targeted haemodynamic therapy in high-risk surgical patients - authors' reply.
Ackland GL, Cecconi M and Pearse RM
The Lancet. Respiratory Medicine, Elsevier vol. 3 (4), e14-e15.  
01-04-2015

Presepsin: solving a soluble (CD14) problem in sepsis?
Ackland GL and Prowle JR
Intensive Care Medicine, Springer Nature vol. 41 (2), 351-353.  
22-01-2015

Man is the new mouse: Elective surgery as a key translational model for multi-organ dysfunction and sepsis
Cain DJ, del Arroyo AG and Ackland GL
Journal of The Intensive Care Society, Sage Publications vol. 16 (2), 154-163.  
07-01-2015

Heart Failure and Perioperative Care
Ackland GL
Asa Refresher Courses in Anesthesiology, Wolters Kluwer vol. 43 (1), 7-14.  
01-01-2015

Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial
Ackland GL, Iqbal S, Paredes LG, Toner A, Lyness C, Jenkins N, Bodger P, Karmali S, Whittle J, Reyes A, Singer M, Hamilton M, Cecconi M, Pearse RM, Mallett SV, Omar RZ and group FTP-OS
The Lancet Respiratory Medicine, Elsevier vol. 3 (1), 33-41.  
16-12-2014

Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning
Barsukevich V, Basalay M, Sanchez J, Mrochek A, Whittle J, Ackland GL, Gourine AV and Gourine A
Basic Research in Cardiology, Springer Nature vol. 110 (1) 
02-12-2014

Chronic kidney disease: a gateway for perioperative medicine
Ackland GL and Laing CM
British Journal of Anaesthesia, Elsevier vol. 113 (6), 902-905.  
10-07-2014

Effect of a Perioperative, Cardiac Output–Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review
Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, Grocott MPW, Ahern A, Griggs K, Scott R, Hinds C and Rowan K
Jama, American Medical Association (Ama) vol. 311 (21), 2181-2190.  
04-06-2014

Myocardial Injury after Noncardiac Surgery
Botto F, Alonso-Coello P, Chan MTV, Villar JC, Xavier D, Srinathan S, Guyatt G, Cruz P, Graham M, Wang CY, Berwanger O, Pearse RM, Biccard BM, Abraham V, Malaga G, Hillis GS, Rodseth RN, Cook D, Polanczyk CA, Szczeklik W, Sessler DI, Sheth T, Ackland GL, Leuwer M, Garg AX, Lemanach Y, Pettit S, Heels-Ansdell D, Luratibuse G and Walsh M
Anesthesiology, Wolters Kluwer vol. 120 (3), 564-578.  
01-03-2014

Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine
Cain DJ, del Arroyo AG and Ackland GL
Intensive Care Medicine Experimental, Springer Nature vol. 2 (1) 
27-02-2014

Administration of intrapulmonary sodium polyacrylate to induce lung injury for the development of a porcine model of early acute respiratory distress syndrome
Henderson WR, Barnbrook J, Dominelli PB, Griesdale DE, Arndt T, Molgat-Seon Y, Foster G, Ackland GL, Xu J, Ayas NT and Sheel AW
Intensive Care Medicine Experimental, Springer Nature vol. 2 (1) 
26-02-2014

Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study
Fragkou PC, Torrance HD, Pearse RM, Ackland GL, Prowle JR, Owen HC, Hinds CJ and O'Dwyer MJ
Crit Care vol. 18 (5), 014-0541.  
01-01-2014

Cardiopulmonary Exercise Capacity and Preoperative Markers of Inflammation
Sultan P, Edwards MR, del Arroyo AG, Cain D, Sneyd JR, Struthers R, Minto G and Ackland GL
Mediators of Inflammation, Hindawi vol. 2014 (1) 
01-01-2014

The relationships between anesthesia, hemodynamics and outcome
Abbott T and Ackland GL
In Perioperative Hemodynamic Monitoring and Goal Directed Therapy, Cambridge University Press (Cup) 224-230.  
01-01-2014

Peripheral Neural Detection of Danger–Associated and Pathogen–Associated Molecular Patterns
Ackland GL, Kazymov V, Marina N, Singer M and Gourine AV
Critical Care Medicine, Wolters Kluwer vol. 41 (6), e85-e92.  
17-05-2013

Autonomic Dysfunction Is the Motor of Chronic Critical Illness
Toner A, Whittle J and Ackland GL
In Annual Update in Intensive Care and Emergency Medicine 2013, Springer Nature 199-209.  
01-01-2013

Perioperative fluid therapy.
Pearse and Ackland
Praxis, Hogrefe Publishing Group vol. 101 (17), 1113-1118.  
01-08-2012

Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones
Mastitskaya S, Marina N, Gourine A, Gilbey MP, Spyer KM, Teschemacher AG, Kasparov S, Trapp S, Ackland GL and Gourine AV
Cardiovascular Research, Oxford University Press (Oup) vol. 95 (4), 487-494.  
27-06-2012

Remote ischaemic pre‐ and delayed postconditioning – similar degree of cardioprotection but distinct mechanisms
Basalay M, Barsukevich V, Mastitskaya S, Mrochek A, Pernow J, Sjöquist P, Ackland GL, Gourine AV and Gourine A
Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, Wiley vol. 97 (8), 908-917.  
31-05-2012

Perioperative fluid therapy
Pearse RM and Ackland GL
The Bmj, Bmj vol. 344 (apr26 1) 
26-04-2012

Microvascular and macrovascular flow are uncoupled in early polymicrobial sepsis
Dyson A, Cone S, Singer M and Ackland GL
British Journal of Anaesthesia, Elsevier vol. 108 (6), 973-978.  
30-03-2012

In Response
Ackland GL
Anesthesia & Analgesia, Wolters Kluwer vol. 114 (3) 
01-03-2012

Preoperative muscle weakness as defined by handgrip strength and postoperative outcomes: a systematic review
Sultan P, Hamilton MA and Ackland GL
Bmc Anesthesiology, Springer Nature vol. 12 (1) 
17-01-2012

Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic Surgery
Ackland GL, Moran N, Cone S, Grocott MPW and Mythen MG
Survey of Anesthesiology, Wolters Kluwer vol. 55 (6), 287-288.  
01-12-2011

Chemical labelling of active serum thioester proteins for quantification
Holm L, Ackland GL, Edwards MR, Breckenridge RA, Sim RB and Offer J
Immunobiology, Elsevier vol. 217 (2), 256-264.  
23-07-2011

Reply from the authors
Ackland GL
British Journal of Anaesthesia, Elsevier vol. 106 (5) 
01-05-2011

Biomarkers to guide perioperative management
Edwards M, Whittle J and Ackland GL
Postgraduate Medical Journal, Oxford University Press (Oup) vol. 87 (1030), 542-549.  
17-01-2011

Morbidity following complex EVAR
Cross J, Edwards M, Harrison S, Richards T and Ackland G
International Journal of Surgery, Wolters Kluwer vol. 9 (7) 
01-01-2011

Arterial Hyperoxia and In-Hospital Mortality After Resuscitation From Cardiac Arrest
Ackland GL, Dyson A and Singer M
Jama, American Medical Association (Ama) vol. 304 (13), 1440-1441.  
06-10-2010

Revised cardiac risk index and postoperative morbidity after elective orthopaedic surgery: a prospective cohort study
Ackland GL, Harris S, Ziabari Y, Grocott M, Mythen M and Investigators S
British Journal of Anaesthesia, Elsevier vol. 105 (6), 744-752.  
28-09-2010

Beta-adrenoreceptor modulation of metabolic, endocrine and immunologic function during critical illness.
Barnes SJ and Ackland GL
Endocrine Metabolic & Immune Disorders - Drug Targets, Bentham Science Publishers vol. 10 (3), 292-300.  
01-09-2010

Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic Surgery
Ackland GL, Moran N, Cone S, Grocott MPW and Mythen MG
Anesthesia & Analgesia, Wolters Kluwer vol. 112 (6), 1375-1381.  
31-08-2010

Defining higher-risk surgery
Ackland GL and Edwards M
Current Opinion in Critical Care, Wolters Kluwer vol. 16 (4), 339-346.  
01-08-2010

Low-molecular-weight polyethylene glycol improves survival in experimental sepsis*
Ackland GL, Del Arroyo AG, Yao ST, Stephens RC, Dyson A, Klein NJ, Singer M and Gourine AV
Critical Care Medicine, Wolters Kluwer vol. 38 (2), 629-636.  
01-02-2010

Cardioprotection, attenuated systemic inflammation, and survival benefit of β1-adrenoceptor blockade in severe sepsis in rats*
Ackland GL, Yao ST, Rudiger A, Dyson A, Stidwill R, Poputnikov D, Singer M and Gourine AV
Critical Care Medicine, Wolters Kluwer vol. 38 (2), 388-394.  
01-02-2010

β1-Adrenoceptor distribution in the rat brain: An immunohistochemical study
Paschalis A, Churchill L, Marina N, Kasymov V, Gourine A and Ackland G
Neuroscience Letters, Elsevier vol. 458 (2), 84-88.  
15-04-2009

The Pivotal Role of Beta-adrenoreceptors in Critical Illness Pathophysiology
Ackland GL and Patterson AJ
In Intensive Care Medicine, Springer Nature 151-161.  
01-01-2009

Strain-specific and pathogen-specific physiologic and genomic differences in murine inflammatory cardiac dysfunction
Ackland G, Agrawal R, Hou C and Patterson A
Critical Care, Springer Nature vol. 13 (Suppl 1) 
01-01-2009

False-Positive Presentation of Battle’s Sign During Hepatic Encephalopathy
Ackland GL, O’Beirne J, Platts AR and Ward SC
Neurocritical Care, Springer Nature vol. 9 (2) 
18-06-2008

Dehydration Induced by Bowel Preparation in Older Adults Does Not Result in Cognitive Dysfunction
Ackland GL, Harrington J, Downie P, Holding JW, Singh-Ranger D, Griva K, Mythen MG and Newman SP
Anesthesia & Analgesia, Wolters Kluwer vol. 106 (3), 924-929.  
01-03-2008

Physiological and pathophysiological roles of extracellular ATP in chemosensory control of breathing
Ackland GL, Kasymov V and Gourine AV
Biochemical Society Transactions, Portland Press vol. 35 (5), 1264-1268.  
25-10-2007

Pre‐operative high sensitivity C‐reactive protein and postoperative outcome in patients undergoing elective orthopaedic surgery
Ackland GL, Scollay JM, Parks RW, De Beaux I and Mythen MG
Anaesthesia, Wiley vol. 62 (9), 888-894.  
09-08-2007

Acute, Severe Hypoglycemia Occurring During General Anesthesia in a Nondiabetic Adult
Ackland GL, Smith M and McGlennan AP
Anesthesia & Analgesia, Wolters Kluwer vol. 105 (2), 553-554.  
01-08-2007

Novel biomarkers in critical care: utility or futility?
Ackland GL and Mythen MG
Critical Care, Springer Nature vol. 11 (6) 
01-01-2007

Physiology of the Gastrointestinal Tract Including Splanchnic Blood Flow and Tonometry
Ackland G and Mythen M
In Gastrointestinal and Colorectal Anesthesia, Taylor & Francis 1-12.  
18-09-2006

Perioperative beta-blockade: beyond myocardial ischaemia
Ackland G
British Journal of Hospital Medicine, Mark Allen Group vol. 67 (5), 276-276.  
01-05-2006

Less Is Not More: A Lack of Evidence for Intraoperative Fluid Restriction Improving Outcome After Major Elective Gastrointestinal Surgery
Hamilton MA, Mythen MG and Ackland GL
Anesthesia & Analgesia, Wolters Kluwer vol. 102 (3), 970-971.  
01-03-2006

NEUROPHYSIOLOGY | Overview
Spyer KM, Ackland GL and Gourine AV
In Encyclopedia of Respiratory Medicine, Elsevier 131-138.  
01-01-2006

NEUROPHYSIOLOGY
Spyer KM, Ackland GL and Gourine AV
In Encyclopedia of Respiratory Medicine: Volume 1-4 
01-01-2006

Low-dose Propofol Infusion for Controlling Acute Hyperspasticity after Withdrawal of Intrathecal Baclofen Therapy
Ackland GL and Fox R
Anesthesiology, Wolters Kluwer vol. 103 (3), 663-665.  
01-09-2005

Negative Pressure Pulmonary Edema as an Unsuspected Imitator of Acute Lung Injury/ARDS
Ackland GL and Mythen MG
Chest Journal, Elsevier vol. 127 (5), 1867-1868.  
01-05-2005

Assessment of preoperative fluid depletion using bioimpedance analysis
Ackland GL, Singh-Ranger D, Fox S, McClaskey B, Down JF, Farrar D, Sivaloganathan M and Mythen MG
British Journal of Anaesthesia, Elsevier vol. 92 (1), 134-136.  
01-01-2004

Effect of low‐dose volatile anaesthetics on ventilation during acute hypoxia
Ackland G
Anaesthesia, Wiley vol. 57 (12), 1224-1226.  
18-11-2002

Physical incompatibility between atracurium and intravenous diclofenac
Ackland G
Anaesthesia, Wiley vol. 56 (3), 294-294.  
01-03-2001

Understanding gastrointestinal perfusion in critical care: so near, and yet so far
Ackland G, Grocott MP and Mythen MG
Critical Care, Springer Nature vol. 4 (5) 
01-01-2000

Red nucleus inhibits breathing during hypoxia in neonates1Paper presented at the conference of Neural Control of Breathing: Molecular to Organismal Perspectives, Madison, WI, 21–25 July 1996.1
Ackland GL, Noble R and Hanson MA
Respiratory Physiology & Neurobiology, Elsevier vol. 110 (2-3), 251-260.  
01-11-1997

Unilateral cooling in the region of locus coeruleus blocks the fall in respiratory output during hypoxia in anaesthetized neonatal sheep
Moore PJ, Ackland GL and Hanson MA
Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, Wiley vol. 81 (6), 983-994.  
01-11-1996

Red nucleus lesions abolish the biphasic respiratory response to isocapnic hypoxia in decerebrate young rabbits.
Waites BA, Ackland GL, Noble R and Hanson MA
The Journal of Physiology, Wiley vol. 495 (1), 217-225.  
15-08-1996

Is the Ventilatory Decline Seen in Newborns during Hypoxaemia Centrally Mediated?
Ackland GL, Moore PJ and Hanson MA
Advances in Experimental Medicine and Biology, Springer Nature vol. 360, 345-348.  
01-01-1994

CLASSICAL AND QUANTUM SIMULATION OF THE SURFACE-PROPERTIES OF ALPHA-AL2O3 - DISCUSSION
THOMAS JM, MACKRODT WC and ACKLAND G
 
01-01-1992