Dr Jianmin Chen
Lecturer in Inflammation and Cardiovascular Medicine; Versus Arthritis Career Development Fellow
The William Harvey Research Institute
Queen Mary University of London
Queen Mary University of London
Research
Cardiomyopathy, HFpEF, Rheumatoid arthritis, Immune cells, Metabolism, Inflammation
Interests
I am interested in modeling the impact of arthritic synovial inflammation on the heart using interconnected organ-on-a-chip systems. Microfluidics which are introduced through an ibidi pump-based system can connect the two organ models, enabling the study of complex multicellular interactions driving cardiac fibrosis. This model will provide valuable insights into disease mechanisms and serve as a platform for screening and evaluating new therapeutics for both arthritis treatment and cardiac protection.Publications
2024

Peh HY and Chen J
Pharmacology & Therapeutics, Elsevier vol. 265
18-11-2024

Suffee N, Le Goff W and Chen J
Frontiers in Immunology, Frontiers vol. 15
01-03-2024
2023

Chen J, Oggero S, Cecconello C, Dalli J, Hayat H, Hjiej Andaloussi A, Sanni S, Jonassen TE and Perretti M
Pharmacological Research, Elsevier vol. 198
21-11-2023

Chen J, Austin-Williams S, O'Riordan CE, Claria-Ribas P, Sugimoto MA, Norling LV, Thiemermann C and Perretti M
Journal of Innate Immunity, Karger Publishers vol. 15 (1), 548-561.
01-01-2023
2022

Costa VV, Sugimoto MA, Hubner J, Bonilha CS, Queiroz-Junior CM, Gonçalves-Pereira MH, Chen J, Gobbetti T, Rodrigues GOL, Bambirra JL, Passos IB, Lopes CEM, Moreira TP, Bonjour K, Melo RC, Oliveira MA, Andrade MVM, Sousa LP, Souza DG, da Costa Santiago H, Perretti M and Teixeira MM
Elife, Elife vol. 11
16-03-2022

Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Moreira SAM, Rathod K, Chen J, Bubb K, Colas R, Khambata RS, Dalli J and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 179 (7), 1450-1469.
14-02-2022
2021

Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP, Filomena F, Nuredini G, Ibrahim AS, Khambata RS, Gupta AK, Moon JC, Kapil V and Ahluwalia A
British Journal of Pharmacology, Wiley vol. 179 (20), 4757-4777.
06-10-2021

Chen J, Norling LV, Mesa JG, Silva MDP, Burton SE, Reutelingsperger C, Perretti M and Cooper D
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 118 (38)
15-09-2021

de Gaetano M, Tighe C, Gahan K, Zanetti A, Chen J, Newson J, Cacace A, Marai M, Gaffney A, Brennan E, Kantharidis P, Cooper ME, Leroy X, Perretti M, Gilroy D, Godson C and Guiry PJ
Journal of Medicinal Chemistry, American Chemical Society (Acs) vol. 64 (13), 9193-9216.
17-06-2021
2020

Chen J, Purvis GSD, Collotta D, Zoubi SA, Sugimoto MA, Cacace A, Martin L, Colas RA, Collino M, Dalli J and Thiemermann C
Frontiers in Immunology, Frontiers Media vol. 11, 2080-2080.
02-09-2020

Aziz Q, Chen J, Moyes AJ, Li Y, Anderson NA, Ang R, Aksentijevic D, Sebastian S, Hobbs AJ, Thiemermann C and Tinker A
Journal of Molecular Medicine, Springer Science and Business Media Llc
06-07-2020

Kieswich JE, Chen J, Alliouachene S, Caton PW, McCafferty K, Thiemermann C and Yaqoob MM
Bio-Protocol, Bio-Protocol vol. 10 (18)
01-01-2020
2019

Yun Y, Chen J, Liu R, Chen W, Liu C, Wang R, Hou Z, Yu Z, Sun Y, IJzerman AP, Heitman LH, Yin X and Guo D
Biochemical Pharmacology, Elsevier vol. 164, 45-52.
21-03-2019
2018

Al Zoubi S, Chen J, Murphy C, Martin L, Chiazza F, Collotta D, Yaqoob MM, Collino M and Thiemermann C
Frontiers in Immunology, Frontiers vol. 9
18-12-2018

Kieswich JE, Chen J, Alliouachene S, Caton PW, McCafferty K, Thiemermann C and Yaqoob MM
Bmc Nephrology, Springer Nature vol. 19 (1)
01-12-2018

de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, Cacace A, Hams E, Maingot C, McLoughlin A, Brennan E, Leroy X, Loscher CE, Fallon P, Perretti M, Godson C and Guiry PJ
European Journal of Medicinal Chemistry, Elsevier vol. 162, 80-108.
23-10-2018

Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C and Ahluwalia A
Faseb J, fj201701303-fj201701303.
28-06-2018

Khan AI, Kapoor A, Chen J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M and Thiemermann C
Shock vol. 49 (6), 675-681.
01-06-2018
2017

Purvis GSD, Chiazza F, Chen J, Loiola RA, Martin L, Fountoulakis N, Gnudi L, Collino M, Thiemermann C and Solito E
Diabetologia, Springer Verlag
30-10-2017

Johnson FL, Patel NSA, Purvis GSD, Chiazza F, Chen J, Sordi R, Hache G, Merezhko VV, Collino M, Yaqoob MM and Thiemermann C
J Am Heart Assoc vol. 6 (7)
03-07-2017

Martin L, Gombert A, Chen J, Liebens J, Verleger J, Kalder J, Marx G, Jacobs M, Thiemermann C and Schuerholz T
Front Immunol, Frontiers Media vol. 8, 681-681.
12-06-2017
2016

Chen J and Thiemermann C
Critical Care Medicine, Wolters Kluwer vol. 44 (6), 1256-1257.
01-06-2016

Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N, Perretti M, Hobbs A, Collino M, Yaqoob M and THIEMERMANN C
Journal of The American Society of Nephrology, American Society of Nephrology
06-05-2016

Zhang W, Zhao X, Xiao Y, Chen J, Han P, Zhang J, Fu H and Kang YJ
Metallomics, Oxford University Press (Oup) vol. 8 (7), 654-662.
01-01-2016
2014

Gobbetti T, Coldewey SM, Chen J, McArthur S, le Faouder P, Cenac N, Flower RJ, Thiemermann C and Perretti M
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 111 (52), 18685-18690.
15-12-2014

Chen J, Chiazza F, Collino M, Patel NSA, Coldewey SM and Thiemermann C
Plos One, Public Library of Science (Plos) vol. 9 (6)
19-06-2014
2013

Sun X, Cai J, Fan X, Han P, Xie Y, Chen J, Xiao Y and Kang YJ
Plos One, Public Library of Science (Plos) vol. 8 (8)
13-08-2013
2012

Xie Y, Chen J, Han P, Yang P, Hou J and Kang YJ
Experimental Biology and Medicine, Frontiers vol. 237 (7), 853-859.
01-07-2012
Grants

Jianmin Chen
£5,000 WHRF William Harvey Research Foundation
14-10-2024 - 13-08-2027

Mauro Perretti, Jianmin Chen and Sharmilee Gnanapavan
£261,605 WHRL William Harvey Research Limited
01-09-2024 - 28-02-2027

Jianmin Chen
£13,904 WHRL William Harvey Research Limited
01-08-2024 - 31-07-2025

Jianmin Chen and Dianne Cooper
£75,000 Barts and the London Charity
18-04-2024 - 31-05-2025

Jianmin Chen and Federica Marelli-Berg
£121,068 HRUK Heart Research UK
01-01-2023 - 30-06-2026

Jianmin Chen
£469,692 AR-UK Versus Arthritis
18-08-2022 - 17-07-2027

Dianne Cooper and Jianmin Chen
£49,919 Barts and the London Charity
17-10-2022 - 31-01-2024