Targeting the tumour vasculature: from vessel destruction to promotion
Guelfi S, Hodivala-Dilke K and Bergers G
Nature Reviews Cancer, Springer Nature vol. 24 (10), 655-675.  
29-08-2024

Treatment with αvβ3-integrin-specific 29P attenuates pressure-overload induced cardiac remodelling after transverse aortic constriction in mice
Njegić A, Laid L, Zi M, Maniati E, Wang J, Chelu A, Wisniewski L, Hunter J, Prehar S, Stafford N, Gilon C, Hoffman A, Weinmüller M, Kessler H, Cartwright EJ and Hodivala-Dilke K
Journal of Molecular and Cellular Cardiology Plus, Elsevier vol. 8 
01-06-2024

Effects of senescence on the tumour microenvironment and response to therapy
Reynolds LE, Maallin S, Haston S, Martinez‐Barbera JP, Hodivala‐Dilke KM and Pedrosa A
The Febs Journal, Wiley vol. 291 (11), 2306-2319.  
01-11-2023

Author Correction: Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D’Amico G, Parsons M, Harwood C, Meier P and Hodivala-Dilke KM
Nature Communications, Springer Nature vol. 14 (1) 
06-09-2023

Primary tumor–derived systemic nANGPTL4 inhibits metastasis
Hübers C, Pari AAA, Grieshober D, Petkov M, Schmidt A, Messmer T, Heyer CM, Schölch S, Kapel SS, Gengenbacher N, Singhal M, Schieb B, Fricke C, Will R, Remans K, Utikal JS, Reissfelder C, Schlesner M, Hodivala-Dilke KM, Kersten S, Goerdt S, Augustin HG and Felcht M
Journal of Experimental Medicine, Rockefeller University Press vol. 220 (1) 
21-10-2022

ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning
D'Amico G, Fernandez I, Gómez-Escudero J, Kim H, Maniati E, Azman MS, Mardakheh FK, Serrels B, Serrels A, Parsons M, Squire A, Birdsey GM, Randi AM, Bolado-Carrancio A, Gangeswaran R, Reynolds LE, Bodrug N, Wang Y, Wang J, Meier P and Hodivala-Dilke KM
Development, The Company of Biologists vol. 149 (13) 
01-07-2022

Suppression of endothelial cell FAK expression reduces pancreatic ductal adenocarcinoma metastasis after gemcitabine treatmentEC FAK regulates gemcitabine treated liver metastasis
Roy-Luzarraga M, Reynolds LE, de Luxán-Delgado B, Maiques O, Wisniewski L, Newport E, Rajeeve V, Drake RJG, Gómez-Escudero J, Richards FM, Weller C, Dormann C, Meng Y-M, Vermeulen PB, Saur D, Sanz-Moreno V, Wong P-P, Géraud C, Cutillas PR and Hodivala-Dilke K
Cancer Research, American Association For Cancer Research (Aacr) vol. 82 (10), 1909-1925.  
29-03-2022

Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth
Newport E, Pedrosa AR, Lees D, Dukinfield M, Carter E, Gomez‐Escudero J, Casado P, Rajeeve V, Reynolds LE, Cutillas PR, Duffy SW, De Luxán Delgado B and Hodivala‐Dilke K
The Journal of Pathology, Wiley vol. 256 (2), 235-247.  
20-12-2021

Improved Immunotherapy Efficacy by Vascular Modulation
Newport EL, Pedrosa AR, Njegic A, Hodivala-Dilke KM and Muñoz-Félix JM
Cancers, Mdpi vol. 13 (20) 
17-10-2021

Correction to: Phosphorylation of pericyte FAK‑Y861 affects tumour cell apoptosis and tumour blood vessel regression
Lees DM, Reynolds LE, Pedrosa AR, Roy-Luzarraga M and Hodivala-Dilke KM
Angiogenesis, Springer Nature vol. 24 (3), 483-487.  
04-07-2021

Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression
Lees DM, Reynolds LE, Pedrosa AR, Roy-Luzarraga M and Hodivala-Dilke KM
Angiogenesis, Springer Nature vol. 24 (3), 471-482.  
17-03-2021

Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice
Delvecchio FR, Fincham REA, Spear S, Clear A, Roy-Luzarraga M, Balkwill FR, Gribben JG, Bombardieri M, Hodivala-Dilke K, Capasso M and Kocher HM
Cellular and Molecular Gastroenterology and Hepatology, Elsevier vol. 12 (5), 1543-1565.  
01-01-2021

Regulation of tumour progression and metastasis by Endothelial-FAK upon chemotherapy treatment
Roy-Luzarraga M, Reynolds L and Hodivala-Dilke K
Pancreatology, Elsevier vol. 20 (8) 
01-12-2020

Association of Low Tumor Endothelial Cell pY397–Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer
Roy-Luzarraga M, Abdel-Fatah T, Reynolds LE, Clear A, Taylor JG, Gribben JG, Chan S, Jones L and Hodivala-Dilke K
Jama Network Open, American Medical Association (Ama) vol. 3 (10) 
01-10-2020

Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma
Abdul Pari AA, Singhal M, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE, Terhardt D, Géraud C, Utikal J, Thomas M, Goerdt S, Hodivala-Dilke KM, Augustin HG and Felcht M
Cancer Research, American Association For Cancer Research (Aacr) vol. 80 (12), 2586-2598.  
15-06-2020

Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D’Amico G, Parsons M, Harwood C, Meier P and Hodivala-Dilke KM
Nature Communications, Springer Nature vol. 11 (1) 
04-06-2020

Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
Wong P-P, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O, Meng Y-M, Meng Q, Bodrug N, Dukinfield MS, Reynolds LE, Elia G, Clear A, Harwood C, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Matchett KP, Henderson NC, Szlosarek PW, Dreger SA, Smith S, Jones JL, Gribben JG, Cutillas PR and Meier P
Cell, Elsevier vol. 181 (6), 1346-1363.e21.  
29-05-2020

Cancer associated fibroblast FAK regulates malignant cell metabolism.
Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J, Newport E, Rajeeve V, Baker A-M, Roy-Luzarraga M, Graham TA, Foster J, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Balkwill FR, Sosabowski J, Cutillas PR, Frezza C, Sancho P and Hodivala-Dilke K
Nature Communications, Nature Research (Part of Springer Nature) vol. 11 (1), 1290-1290.  
10-03-2020

“Splitting the matrix”: intussusceptive angiogenesis meets MT1‐MMP
D'Amico G, Muñoz‐Félix JM, Pedrosa AR and Hodivala‐Dilke KM
Embo Molecular Medicine, Springer Nature vol. 12 (2) 
20-12-2019

Repurposing an anti‐cancer agent for the treatment of hypertrophic heart disease
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC, Margulies KB, Sanz‐Moreno V, Hobbs A and Hodivala‐Dilke K
The Journal of Pathology, Wiley vol. 249 (4), 523-535.  
30-10-2019

Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations
Li J, Fukase Y, Shang Y, Zou W, Muñoz-Félix JM, Buitrago L, van Agthoven J, Zhang Y, Hara R, Tanaka Y, Okamoto R, Yasui T, Nakahata T, Imaeda T, Aso K, Zhou Y, Locuson C, Nesic D, Duggan M, Takagi J, Vaughan RD, Walz T, Hodivala-Dilke K, Teitelbaum SL, Arnaout MA, Filizola M, Foley MA and Coller BS
Acs Pharmacology & Translational Science, American Chemical Society (Acs) vol. 2 (6), 387-401.  
02-08-2019

Tumour angiogenesis is differentially regulated by endothelial cell Focal Adhesion Kinase tyrosine-397 and -861 phosphorylation
Pedrosa A-R, BODRUG N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T and Hodivala-Dilke K
Cancer Research, American Association For Cancer Research 
12-06-2019

Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
Li Z, Solomonidis EG, Meloni M, Taylor RS, Duffin R, Dobie R, Magalhaes MS, Henderson BEP, Louwe PA, D’Amico G, Hodivala-Dilke KM, Shah AM, Mills NL, Simons BD, Gray GA, Henderson NC, Baker AH and Brittan M
European Heart Journal, Oxford University Press (Oup) vol. 40 (30), 2507-2520.  
04-06-2019

C-type natriuretic peptide co-ordinates cardiac structure and function
Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS and Hobbs AJ
European Heart Journal, Oxford University Press (Oup) vol. 41 (9), 1006-1020.  
21-03-2019

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia.
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A, Gadaleta E, Rhys HI, Kennedy PT, Hermida MA, Chang T-Y, Shaw PE, Reynolds LE, McKay TR, Wang H-W, Ribeiro PS, Plevin MJ, Lagos D, Lemoine NR, Rajan P, Graham TA, Chelala C, Hodivala-Dilke KM, Spendlove I and Sharp TV
Embo Mol Med 
21-06-2018

Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3
Weinmüller M, Rechenmacher F, Marelli UK, Reichart F, Kapp TG, Räder AFB, Di Leva FS, Marinelli L, Novellino E, Muñoz‐Félix JM, Hodivala‐Dilke K, Schumacher A, Fanous J, Gilon C, Hoffman A and Kessler H
Angewandte Chemie International Edition, Wiley vol. 56 (51), 16405-16409.  
23-11-2017

Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium‐specific FAK‐kinase dead mice
Alexopoulou AN, Lees DM, Bodrug N, Lechertier T, Fernandez I, D'Amico G, Dukinfield M, Batista S, Tavora B, Serrels B and Hodivala‐Dilke K
The Journal of Pathology, Wiley vol. 242 (3), 358-370.  
01-06-2017

Multiple roles of integrin-α3 at the neuromuscular junction
Ross JA, Webster RG, Lechertier T, Reynolds LE, Turmaine M, Bencze M, Jamshidi Y, Cetin H, Muntoni F, Beeson D, Hodilvala-Dilke K and Conti FJ
Journal of Cell Science, The Company of Biologists vol. 130 (10), 1772-1784.  
06-04-2017

Dual role of pericyte α6β1-integrin in tumour blood vessels
Reynolds LE, D'Amico G, Lechertier T, Papachristodoulou A, Muñoz-Félix JM, De Arcangelis A, Baker M, Serrels B and Hodivala-Dilke KM
Journal of Cell Science, The Company of Biologists vol. 130 (9), 1583-1595.  
13-03-2017

Correction: A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma

Clinical Cancer Research, American Association For Cancer Research (Aacr) vol. 23 (3), 870-870.  
31-01-2017

Exploring Novel Methods for Modulating Tumor Blood Vessels in Cancer Treatment
Wong P-P, Bodrug N and Hodivala-Dilke KM
Current Biology, Elsevier vol. 26 (21), r1161-r1166.  
01-11-2016

αvβ3 Integrin and tumour blood vessels—learning from the past to shape the future
Demircioglu F and Hodivala-Dilke K
Current Opinion in Cell Biology, Elsevier vol. 42, 121-127.  
27-07-2016

Molecular Pathways: Endothelial Cell FAK--A Target for Cancer Treatment
Roy-Luzarraga M and Hodivala-Dilke K
Clinical Cancer Research, American Association For Cancer Research vol. 22 (15), 3718-3724.  
04-06-2016

Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma
Di Maggio F, Arumugam P, Delvecchio FR, Batista S, Lechertier T, Hodivala-Dilke K and Kocher HM
Pancreatology, Elsevier 
01-06-2016

A promyelocytic leukemia protein-thrombospondin 2 axis and the risk of relapse in neuroblastoma.
Dvorkina M, Nieddu V, Chakelam S, Pezzolo A, Cantilena S, Leite AP, Chayka O, Regad T, Pistorio A, Sementa AR, Virasami A, Barton J, Montano X, Lechertier T, Brindle N, Morgenstern D, LE Bras M, Burns A, Saunders N, Hodivala-Dilke K, Bagella L, de The H, Anderson J, Sebire N, Pistoia V, Sala A and Salomoni P
Clinical Cancer Research, American Association For Cancer Research 
13-04-2016

Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC.
Martins VL, Caley MP, Moore K, Szentpetery Z, Marsh ST, Murrell DF, Kim MH, Avari M, McGrath JA, Cerio R, Kivisaari A, Kähäri VM, Hodivala-Dilke K, Brennan CH, Chen M, Marshall JF and O'Toole EA
J Natl Cancer Inst vol. 108 (1) 
16-10-2015

Interleukin-6 Stimulates Defective Angiogenesis
Gopinathan G, Milagre C, Pearce OMT, Reynolds LE, Hodivala-Dilke K, Leinster DA, Zhong H, Hollingsworth RE, Thompson R, Whiteford JR and Balkwill F
Cancer Research, American Association For Cancer Research (Aacr) vol. 75 (15), 3098-3107.  
01-08-2015

Abstract 4162: Interleukin–6 stimulates defective angiogenesis
Gopinathan G, Milagre C, Pearce OMT, Reynolds L, Hodivala-Dilke K, Leinster A, Zhong H, Hollingsworth RE, Thompson R, Whiteford JR and Balkwill F
Cancer Research, American Association For Cancer Research (Aacr) vol. 75 (15_Supplement), 4162-4162.  
01-08-2015

Dual-Action Combination Therapy Enhances Angiogenesis while Reducing Tumor Growth and Spread
Wong P-P, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford MRL, Scudamore CL, Cereser B, Crnogorac-Jurcevic T, McDonald S, Elia G, Hagemann T, Kocher HM and Hodivala-Dilke KM
Cancer Cell, Elsevier vol. 27 (1), 123-137.  
01-01-2015

The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
Birdsey GM, Shah AV, Dufton N, Reynolds LE, Almagro LO, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Göttgens B, Hodivala-Dilke K, Gerhardt H, Adams RH and Randi AM
Developmental Cell, Elsevier vol. 32 (1), 82-96.  
01-01-2015

Generation of point-mutant FAK knockin mice.
Tavora B, Batista S, Alexopoulou AN, Kostourou V, Fernandez I, Robinson SD, Lees DM, Serrels B and Hodivala-Dilke K
Genesis vol. 52 (11), 907-915.  
01-11-2014

Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.
Tavora B, Reynolds LE, Batista S, Demircioglu F, Fernandez I, Lechertier T, Lees DM, Wong P-P, Alexopoulou A, Elia G, Clear A, Ledoux A, Hunter J, Perkins N, Gribben JG and Hodivala-Dilke KM
Nature vol. 514 (7520), 112-116.  
02-10-2014

Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.
Batista S, Maniati E, Reynolds LE, Tavora B, Lees DM, Fernandez I, Elia G, Casanovas O, Lo Celso C, Hagemann T and Hodivala-Dilke K
Nat Commun vol. 5 
01-10-2014

Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer.
Alexopoulou AN, Ho-Yen CM, Papalazarou V, Elia G, Jones JL and Hodivala-Dilke K
Bmc Cancer vol. 14 
02-04-2014

Acute depletion of endothelial β3-integrin transiently inhibits tumor growth and angiogenesis in mice.
Steri V, Ellison TS, Gontarczyk AM, Weilbaecher K, Schneider JG, Edwards D, Fruttiger M, Hodivala-Dilke KM and Robinson SD
Circulation Research, American Heart Association vol. 114 (1), 79-91.  
03-01-2014

The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling
Shah AV, Birdsey GM, Reynolds LE, Dufton N, Almagro LO, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Goettgens B, Hodivala-Dilke K, Gerhardt H, Adams RH and Randi AM
Angiogenesis vol. 17 (3), 715-715.  
01-01-2014

Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.
Martino-Echarri E, Fernández-Rodríguez R, Rodríguez-Baena FJ, Barrientos-Durán A, Torres-Collado AX, Plaza-Calonge MDC, Amador-Cubero S, Cortés J, Reynolds LE, Hodivala-Dilke KM and Rodríguez-Manzaneque JC
Int J Cancer vol. 133 (10), 2315-2324.  
15-11-2013

Fascin 1 is dispensable for developmental and tumour angiogenesis.
Ma Y, Reynolds LE, Li A, Stevenson RP, Hodivala-Dilke KM, Yamashiro S and Machesky LM
Biol Open vol. 2 (11), 1187-1191.  
01-01-2013

Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice.
Jones DT, Lechertier T, Reynolds LE, Mitter R, Robinson SD, Kirn-Safran CB and Hodivala-Dilke KM
Dis Model Mech vol. 6 (1), 115-124.  
01-01-2013

Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.
Baker M, Reynolds LE, Robinson SD, Lees DM, Parsons M, Elia G and Hodivala-Dilke K
Plos One vol. 8 (5) 
01-01-2013

FAK-heterozygous mice display enhanced tumour angiogenesis.
Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR and Hodivala-Dilke K
Nat Commun vol. 4 
01-01-2013

Focal adhesion kinase and tumour angiogenesis.
Lechertier T and Hodivala-Dilke K
J Pathol vol. 226 (2), 404-412.  
01-01-2012

Gene expression analysis in human breast cancer associated blood vessels.
Jones DT, Lechertier T, Mitter R, Herbert JMJ, Bicknell R, Jones JL, Li J-L, Buffa F, Harris AL and Hodivala-Dilke K
Plos One vol. 7 (10) 
01-01-2012

Use of the mouse aortic ring assay to study angiogenesis.
Baker M, Robinson SD, Lechertier T, Barber PR, Tavora B, D'Amico G, Jones DT, Vojnovic B and Hodivala-Dilke K
Nat Protoc vol. 7 (1), 89-104.  
22-12-2011

The role of β3-integrins in tumor angiogenesis: context is everything.
Robinson SD and Hodivala-Dilke KM
Curr Opin Cell Biol vol. 23 (5), 630-637.  
01-10-2011

Abstract SY16-03: Dose matters and angiogenesis
Hodivala-Dilke KM
Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (8_Supplement) 
15-04-2011

Abstract 3479: Claudin-14: A novel regulator of angiogenesis
Baker M, Robinson SD, Hodivala-Dilke K and Ben-Yosef T
Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (8_Supplement), 3479-3479.  
15-04-2011

Abstract 517: Deficiency of FAK in the bone marrow compartment enhances tumour metastasis
Batista SA, Reynolds L, Tavora B and Hodivala-Dilke K
Cancer Research, American Association For Cancer Research (Aacr) vol. 71 (8_Supplement), 517-517.  
15-04-2011

Dose matters and angiogenesis
Hodivala-Dilke KM
Cancer Research vol. 71 
15-04-2011

Measuring angiogenesis in mice.
Tavora B, Batista S and Hodivala-Dilke K
Methods Mol Biol vol. 769, 351-358.  
01-01-2011

Endothelial FAK is required for tumour angiogenesis.
Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M, Parsons M and Hodivala-Dilke KM
Embo Mol Med vol. 2 (12), 516-528.  
01-12-2010

Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.
da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, Iruela-Arispe ML, Dipersio CM, Kreidberg JA and Hodivala-Dilke KM
Am J Pathol vol. 177 (3), 1534-1548.  
01-09-2010

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome (Corrigendum)
Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, Turnell AS, Kermorgant S, Imhof BA, Adams RH, Fisher EMC, Tybulewicz VLJ, Hart IR and Hodivala-Dilke KM
Nature vol. 466 (7304) 
15-07-2010

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.
Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, Turnell AS, Kermorgant S, Imhof BA, Adams R, Fisher EMC, Tybulewicz VLJ, Hart IR and Hodivala-Dilke KM
Nature vol. 465 (7299), 813-817.  
10-06-2010

Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.
Worth DC, Hodivala-Dilke K, Robinson SD, King SJ, Morton PE, Gertler FB, Humphries MJ and Parsons M
J Cell Biol vol. 189 (2), 369-383.  
19-04-2010

Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.
D'Amico G, Robinson SD, Germain M, Reynolds LE, Thomas GJ, Elia G, Saunders G, Fruttiger M, Tybulewicz V, Mavria G and Hodivala-Dilke KM
Plos One vol. 5 (3) 
22-03-2010

Deficiency of bone marrow beta3-integrin enhances non-functional neovascularization.
Watson AR, Pitchford SC, Reynolds LE, Direkze N, Brittan M, Alison MR, Rankin S, Wright NA and Hodivala-Dilke KM
J Pathol vol. 220 (4), 435-445.  
01-03-2010

Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis.
Germain M, De Arcangelis A, Robinson SD, Baker M, Tavora B, D'Amico G, Silva R, Kostourou V, Reynolds LE, Watson A, Jones JL, Georges-Labouesse E and Hodivala-Dilke K
J Pathol vol. 220 (3), 370-381.  
01-02-2010

Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis.
Robinson SD, Reynolds LE, Kostourou V, Reynolds AR, da Silva RG, Tavora B, Baker M, Marshall JF and Hodivala-Dilke KM
J Biol Chem vol. 284 (49), 33966-33981.  
04-12-2009

Regulation of lymphatic-blood vessel separation by endothelial Rac1.
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V and Hodivala-Dilke KM
Development vol. 136 (23), 4043-4053.  
01-12-2009

Will integrin inhibitors have proangiogenic effects in the clinic? Reply
Reynolds AR and Hodivala-Dilke KM
Nat Med vol. 15 (7), 727-727.  
01-07-2009

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.
Reynolds AR, Hart IR, Watson AR, Welti JC, Silva RG, Robinson SD, Da Violante G, Gourlaouen M, Salih M, Jones MC, Jones DT, Saunders G, Kostourou V, Perron-Sierra F, Norman JC, Tucker GC and Hodivala-Dilke KM
Nat Med vol. 15 (4), 392-400.  
01-04-2009

The role of cell adhesion pathways in angiogenesis.
Ramjaun AR and Hodivala-Dilke K
Int J Biochem Cell Biol vol. 41 (3), 521-530.  
01-03-2009

alpha v beta 3 integrin and angiogenesis: a moody integrin in a changing environment
Hodivala-Dilke K
Curr Opin Cell Biol vol. 20 (5), 514-519.  
01-10-2008

Integrins - The keys to unlocking angiogenesis
Silva R, D'Amico G, Hodivala-Dilke KM and Reynolds LE
Arterioscl Throm Vas vol. 28 (10), 1703-1713.  
01-10-2008

The role of beta 3-integrin on bone marrow-derived cells in inflammatory bowel diseases
Schier S, Watson A, Hodivala-Dilke K and Wright NA
Gastroenterology vol. 134 (4), A257-A257.  
01-04-2008

alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice.
Reynolds LE, Conti FJ, Silva R, Robinson SD, Iyer V, Rudling R, Cross B, Nye E, Hart IR, Dipersio CM and Hodivala-Dilke KM
J Clin Invest vol. 118 (3), 965-974.  
01-03-2008

Efficient, inducible Cre-recombinase activation in vascular endothelium
Claxton S, Kostourou V, Jadeja S, Chambon P, Hodivala-Dilke K and Fruttiger M
Genesis vol. 46 (2), 74-80.  
01-02-2008

Farnesyltransferase inhibitors target multiple endothelial cell functions in angiogenesis.
Scott AN, Hetheridge C, Reynolds AR, Nayak V, Hodivala-Dilke K and Mellor H
Angiogenesis vol. 11 (4), 337-346.  
01-01-2008

Regulation of COX-2-mediated signaling by alpha 3 type IV noncollagenous domain in tumor angiogenesis
Boosani CS, Mannam AP, Cosgrove D, Silva R, Hodivala-Dilke KM, Keshamouni VG and Sudhakar A
Blood vol. 110 (4), 1168-1177.  
15-08-2007

Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis.
Piqueras L, Reynolds AR, Hodivala-Dilke KM, Alfranca A, Redondo JM, Hatae T, Tanabe T, Warner TD and Bishop-Bailey D
Arterioscler Thromb Vasc Biol vol. 27 (1), 63-69.  
01-01-2007

Requirements for apoptotic cell contact in regulation of macrophage responses
Lucas M, Stuart LM, Zhang A, Hodivala-Dilke K, Febbraio M, Silverstein R, Savill J and Lacy-Hulbert A
J Immunol vol. 177 (6), 4047-4054.  
15-09-2006

Bone marrow-derived stromal cells express lineage-related messenger RNA species.
Direkze NC, Jeffery R, Hodivala-Dilke K, Hunt T, Playford RJ, Elia G, Poulsom R, Wright NA and Alison MR
Cancer Res vol. 66 (3), 1265-1269.  
01-02-2006

Generation of genetically modified embryonic stem cells for the development of knockout mouse animal model systems.
Robinson SD, Wilson S and Hodivala-Dilke KM
Methods Mol Med vol. 120, 465-477.  
01-01-2006

Primary mouse endothelial cell culture for assays of angiogenesis.
Reynolds LE and Hodivala-Dilke KM
Methods Mol Med vol. 120, 503-509.  
01-01-2006

Therapeutic expression of the platelet-specific integrin, alpha IIb beta 3, in a murine model for Glanzmann thrombasthenia
Fang J, Hodivala-Dilke K, Johnson BD, Du LM, Hynes RO, White GC and Wilcox DA
Blood vol. 106 (8), 2671-2679.  
15-10-2005

Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth
Lamagna C, Hodivala-Dilke KM, Imhof BA and Aurrand-Lions M
Cancer Res vol. 65 (13), 5703-5710.  
01-07-2005

Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion.
Brittan M, Braun KM, Reynolds LE, Conti FJ, Reynolds AR, Poulsom R, Alison MR, Wright NA and Hodivala-Dilke KM
J Pathol vol. 205 (1), 1-13.  
01-01-2005

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.
McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D, Chambon P, Grant SGN and Frame MC
Genes Dev vol. 18 (24), 2998-3003.  
15-12-2004

Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts.
Direkze NC, Hodivala-Dilke K, Jeffery R, Hunt T, Poulsom R, Oukrif D, Alison MR and Wright NA
Cancer Res vol. 64 (23), 8492-8495.  
01-12-2004

Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice.
Reynolds AR, Reynolds LE, Nagel TE, Lively JC, Robinson SD, Hicklin DJ, Bodary SC and Hodivala-Dilke KM
Cancer Res vol. 64 (23), 8643-8650.  
01-12-2004

Beta3-integrin regulates vascular endothelial growth factor-A-dependent permeability.
Robinson SD, Reynolds LE, Wyder L, Hicklin DJ and Hodivala-Dilke KM
Arterioscler Thromb Vasc Biol vol. 24 (11), 2108-2114.  
01-11-2004

Integrins and angiogenesis: unlocking the route to gene therapy.
Mistry A, Harbottle R, Hart S and Hodivala-Dilke KM
Curr Opin Mol Ther vol. 5 (6), 603-610.  
01-12-2003

Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis.
Alugupalli KR, Michelson AD, Joris I, Schwan TG, Hodivala-Dilke K, Hynes RO and Leong JM
Blood vol. 102 (8), 2843-2850.  
15-10-2003

Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes.
Wan H, Stone MG, Simpson C, Reynolds LE, Marshall JF, Hart IR, Hodivala-Dilke KM and Eady RAJ
J Cell Sci vol. 116 (Pt 20), 4239-4248.  
15-10-2003

Integrins in angiogenesis: multitalented molecules in a balancing act.
Hodivala-Dilke KM, Reynolds AR and Reynolds LE
Cell Tissue Res vol. 314 (1), 131-144.  
01-10-2003

alpha3beta1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis.
Conti FJA, Rudling RJ, Robson A and Hodivala-Dilke KM
J Cell Sci vol. 116 (Pt 13), 2737-2747.  
01-07-2003

Nanoparticle-mediated gene delivery to tumour neovasculature.
Reynolds AR, Moein Moghimi S and Hodivala-Dilke K
Trends Mol Med vol. 9 (1), 2-4.  
01-01-2003

Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted mice.
Direkze NC, Forbes SJ, Brittan M, Hunt T, Jeffery R, Preston SL, Poulsom R, Hodivala-Dilke K, Alison MR and Wright NA
Stem Cells vol. 21 (5), 514-520.  
01-01-2003

Diversity of desmoplakin expression in basal palm keratinocytes: A possible clue to the identification of epidermal stem cells
Wan H, Marshall J, Reynolds LE, Stone MG, McGrath JA, Hodivala-Dilke KM and Eady RAJ
J Invest Dermatol vol. 119 (3), 714-714.  
01-09-2002

CD36 or alphavbeta3 and alphavbeta5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ murine dendritic cells.
Schulz O, Pennington DJ, Hodivala-Dilke K, Febbraio M and Reis e Sousa C
J Immunol vol. 168 (12), 6057-6065.  
15-06-2002

Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies.
Francis SE, Goh KL, Hodivala-Dilke K, Bader BL, Stark M, Davidson D and Hynes RO
Arterioscler Thromb Vasc Biol vol. 22 (6), 927-933.  
01-06-2002

Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon.
Brittan M, Hunt T, Jeffery R, Poulsom R, Forbes SJ, Hodivala-Dilke K, Goldman J, Alison MR and Wright NA
Gut vol. 50 (6), 752-757.  
01-06-2002

Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon
Forbes SJ, Hunt T, Brittan M, Jeffery R, Poulsom R, Hodivala-Dilke K, Alison MR and Wright NA
Gut vol. 50, A35-A35.  
01-04-2002

Bone marrow derivation of intestinal subepithelial myofibroblasts in the mouse and human small intestine and colon
Brittan M, Hunt T, Jeffery R, Poulsom R, Forbes S, Hodivala-Dilke K, Alison M and Wright NA
Gastroenterology vol. 122 (4), A95-A96.  
01-04-2002

Primary mouse keratinocyte culture.
Hodivala-Dilke K
Methods Mol Biol vol. 188, 139-144.  
01-01-2002

Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins.
Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, Sheppard D, Hynes RO and Hodivala-Dilke KM
Nat Med vol. 8 (1), 27-34.  
01-01-2002

The diverse roles of integrins and their ligands in angiogenesis.
Hynes RO, Lively JC, McCarty JH, Taverna D, Francis SE, Hodivala-Dilke K and Xiao Q
Cold Spring Harb Symp Quant Biol vol. 67, 143-153.  
01-01-2002

Sticky science is skin deep
Hodivala-Dilke K
Journal of Cell Science, The Company of Biologists vol. 114 (20), 3582-3582.  
15-10-2001

Kidney from bone marrow in humans and mice.
Forbes SJ, Wyles SM, Ryan ED, Navaratnarasah S, Hodivala-Dilke KM, Jeffrey R, Hunt T, Alison MR, Cook T, Pusey C, Poulsom R and Wright NA
J Pathol vol. 195, 3A-3A.  
01-09-2001

Bone marrow contributes to renal parenchymal turnover and regeneration.
Poulsom R, Forbes SJ, Hodivala-Dilke K, Ryan E, Wyles S, Navaratnarasah S, Jeffery R, Hunt T, Alison M, Cook T, Pusey C and Wright NA
J Pathol vol. 195 (2), 229-235.  
01-09-2001

Bone marrow stem cells make hepatocytes with replicative potential.
Forbes SJ, Alison MR, Hodivala-Dilke KM, Jeffery R, Poulsom R and Wright NA
Gastroenterology vol. 120 (5), A62-A62.  
01-04-2001

Hepatocytes derived from bone marrow stem cells demonstrate polyploidisation
Forbes SJ, Hodivala-Dilke KM, Jeffery R, Alison MR, Poulsom R, Thomas H and Wright NA
J Hepatol vol. 34, 20-21.  
01-04-2001

Hepatocytes derived from bone marrow stem cells show polyploidization in humans and mice
Forbes SJ, Hodivala-Dilke KM, Jeffery R, Hunt T, Alison MR, Poulsom R and Wright NA
Gut vol. 48, A65-A66.  
01-03-2001

In vitro characterization of integrin-deficient endothelial cells and aortic explants
Lively JC, Hodivala-Dilke K and Hynes RO
Mol Biol Cell vol. 11, 51A-51A.  
01-12-2000

Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts
McHugh KP, Hodivala-Dilke K, Zheng M-H, Namba N, Lam J, Novack D, Feng X, Ross FP, Hynes RO and Teitelbaum SL
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 105 (4), 433-440.  
15-02-2000

Integrins in vascular development
Hynes RO, Bader BL and Hodivala-Dilke K
Brazilian Journal of Medical and Biological Research, Fapunifesp (Scielo) vol. 32 (5), 501-510.  
01-05-1999

β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
Hodivala-Dilke KM, McHugh KP, Tsakiris DA, Rayburn H, Crowley D, Ullman-Culleré M, Ross FP, Coller BS, Teitelbaum S and Hynes RO
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 103 (2), 229-238.  
15-01-1999

Insights and Questions Arising from Studies of a Mouse Model of Glanzmann Thrombasthenia
Hynes RO and Hodivala-Dilke KM
Thrombosis and Haemostasis, Thieme vol. 82 (02), 481-485.  
01-01-1999

Hemostasis in the Mouse (Mus musculus): A Review
Tsakiris DA, Scudder L, Hodivala-Dilke K, Hynes RO and Coller BS
Thrombosis and Haemostasis, Thieme vol. 81 (02), 177-188.  
01-01-1999

Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes
Hodivala-Dilke KM, DiPersio CM, Kreidberg JA and Hynes RO
Journal of Cell Biology, Rockefeller University Press vol. 142 (5), 1357-1369.  
07-09-1998

alpha 3 beta 1 integrin is required for normal development of the epidermal basement membrane
DiPersio CM, HodivalaDilke KM, Jaenisch R, Kreidberg JA and Hynes RO
J Cell Biol vol. 137 (3), 729-742.  
05-05-1997

Calcium-Induced Changes in Distribution and Solubility of Cadherins, Integrins and Their Associated Cytoplasmic Proteins in Human Keratinocytes
Braga VMM, Hodivala KJ and Watt FM
Cell Communication & Adhesion, Taylor & Francis vol. 3 (3), 201-215.  
01-01-1995

Cell Adhesion: Fibronectin and integrin knockouts come unstuck
Watt FM and Hodivala KJ
Current Biology, Elsevier vol. 4 (3), 270-272.  
01-03-1994

Integrin expression and function in HPV 16-immortalised human keratinocytes in the presence or absence of v-Ha-ras. Comparison with cervical intraepithelial neoplasia.
Hodivala KJ, Pei XF, Liu QY, Jones PH, Rytina ER, Gilbert C, Singer A and Watt FM
Oncogene vol. 9 (3), 943-948.  
01-03-1994

Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation
Hodivala K and Watt F
Journal of Cell Biology, Rockefeller University Press vol. 124 (4), 589-600.  
15-02-1994

Detection of mature malaria infections in live mosquitoes
Billingsley PF, Hodivala KJ, Winger LA and Sinden RE
Transactions of The Royal Society of Tropical Medicine and Hygiene, Oxford University Press (Oup) vol. 85 (4), 450-453.  
01-07-1991

An antigen specific to the liver stage of rodent malaria recognized by a monoclonal antibody
SUHRBIER A, WINGER L, O'DOWD C, HODIVALA K and SINDEN RE
Parasite Immunology, Wiley vol. 12 (4‐5), 473-481.  
01-09-1990

The development and routine application of high-density exoerythrocytic-stage cultures of Plasmodium berghei.
Sinden RE, Suhrbier A, Davies CS, Fleck SL, Hodivala K and Nicholas JC
Bulletin of The World Health Organization vol. 68 Suppl (Suppl), 115-125.  
01-01-1990

A liver-stage specific antigen of P. berghei identified by a monoclonal antibody.
Winger L, Suhrbier A, O'Dowd CA, Hodivala KJ and Sinden RE
Bulletin of The World Health Organization vol. 68 Suppl (Suppl), 172-177.  
01-01-1990

Contrasts in antigen expression in the erythrocytic and exoerythrocytic stages of rodent malaria
Suhrbier A, Wiser MF, Winger L, Harte P, Newton MF, Hodivala KJ, Nicholas J and Sinden RE
Parasitology, Cambridge University Press (Cup) vol. 99 (2), 165-170.  
01-10-1989