Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L, Golding M, Blacksell IA, Giblin MJ, Jaworska E, Bishop CL, Voisin M-B, Gaston-Massuet C, Fossati-Jimack L, Pitzalis C, Cooper D, Nightingale TD, Lopez-Otin C, Lewis MJ and Nourshargh S (2024). Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues. Springer Nature  EMBO Reports  vol. 25, (9) 3842-3869.  

Corsiero E, Caliste M, Jagemann L, Fossati-Jimack L, Goldmann K, Cubuk C, Ghirardi GM, Prediletto E, Rivellese F, Alessandri C, Hopkinson M, Javaheri B, Pitsillides AA, Lewis MJ, Pitzalis C and Bombardieri M (2024). Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response. American Society for Clinical Investigation  Journal of Clinical Investigation  vol. 134, (12)  

Pontarini E, Sciacca E, Chowdhury F, Grigoriadou S, Rivellese F, Murray‐Brown WJ, Lucchesi D, Fossati‐Jimack L, Nerviani A, Jaworska E, Ghirardi GM, Giacomassi C, Emery P, Ng WF, Sutcliffe N, Everett C, Fernandez C, Tappuni A, Seror R, Mariette X, Porcher R, Cavallaro G, Pulvirenti A, Verstappen GM, de Wolff L, Arends S, Bootsma H, Lewis MJ, Pitzalis C and Bowman SJ (2024). Serum and Tissue Biomarkers Associated With Composite of Relevant Endpoints for Sjögren Syndrome (CRESS) and Sjögren Tool for Assessing Response (STAR) to B Cell–Targeted Therapy in the Trial of Anti–B Cell Therapy in Patients With Primary Sjögren Syndrome (TRACTISS). Wiley  Arthritis & Rheumatology  vol. 76, (5) 763-776.  

Çubuk C, Lau R, Cutillas P, Rajeeve V, John CR, Surace AEA, Hands R, Fossati-Jimack L, Lewis MJ and Pitzalis C (2024). Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways and differentiates inflammatory pathotypes. Springer Nature  Arthritis Research & Therapy  vol. 26, (1)  

Boutet M-A, Nerviani A, Fossati-Jimack L, Hands-Greenwood R, Ahmed M, Rivellese F and Pitzalis C (2023). Comparative analysis of late-stage rheumatoid arthritis and osteoarthritis reveals shared histopathological features. Elsevier  Osteoarthritis and Cartilage  vol. 32, (2) 166-176.  

Ghirardi GM, Nerviani A, Fossati-Jimack L, Pontarini E, Italiani P, Pratesi F, Abdelmoaty S, Högerkorp C and Pitzalis C (2023). AB0067 MODE OF ACTION AND TARGET INVESTIGATION OF THE NEW ANTI-RHEUMATIC DRUG RABEXIMOD. BMJ   

Shikh MEME, Sayed RE, Aly NAR, Prediletto E, Hands R, Fossati-Jimack L, Bombardieri M, Lewis MJ and Pitzalis C (2022). Follicular dendritic cell differentiation is associated with distinct synovial pathotype signatures in rheumatoid arthritis. Frontiers  Frontiers in Medicine  vol. 9,  

Humby F, Durez P, Buch MH, Lewis MJ, Bombardieri M, John C, Rizvi H, Warren L, Peel J, Fossati-Jimack L, Hands RE, Giorli G, Rivellese F, Cañete JD, Taylor PC, Sasieni P, Fonseca JE, Choy E and Pitzalis C (2022). Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients:the R4-RA RCT. National Institute for Health and Care Research  Efficacy and Mechanism Evaluation  vol. 9, (7) 1-58.  

Cooles FAH, Tarn J, Lendrem DW, Naamane N, Lin CM, Millar B, Maney NJ, Anderson AE, Thalayasingam N, Diboll J, Bondet V, Duffy D, Barnes MR, Smith GR, Ng S, Watson D, Henkin R, Cope AP, Reynard LN, Pratt AG, Isaacs JD, Hughes-Morley A, Walker A, Cuza A, Gallagher-Syed A, Anderson A, Haynes A, Filer A and Long A (2022). Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming. Elsevier  Annals of the Rheumatic Diseases  vol. 81, (9) 1214-1223.  

Elshikh M, El Sayed R, Aly N, Prediletto E, Hands R, Fossati-Jimack L, Bombardieri M, Lewis M and Pitzalis C (2022). POS0431 PDGF-BB, TNF-α, AND LT-β REGULATE FOLLICULAR DENDRITIC CELL DEVELOPMENT IN THE RHEUMATOID SYNOVIUM. Elsevier  Annals of the Rheumatic Diseases  vol. 81, (Suppl 1) 470.1-47470.  

Surace A, Sciacca E, Goldmann K, Rivellese F, Cubuk C, Giorli G, Fossati-Jimack L, Ahmed M, Prediletto E, Bombardieri M, Lewis M and Pitzalis C (2022). OP0077 SYNOVIAL RNA-SEQ ANALYSIS OF THE R4RA TRIAL IDENTIFIES SIGNATURES OF TREATMENT RESISTANCE AND REFRACTORY STATE IN RHEUMATOID ARTHRITIS. Elsevier  Annals of the Rheumatic Diseases  vol. 81, (Suppl 1) 52.2-5253.  

Rivellese F, Cubuk C, Surace A, Goldmann K, Sciacca E, Giorli G, Nerviani A, Fossati-Jimack L, Thorborn G, Bombardieri M, Barnes M, Lewis M and Pitzalis C (2022). OP0085 CELL LINEAGE-SPECIFIC TRANSCRIPT DECONVOLUTION OF SYNOVIAL BIOPSIES FROM THE R4RA TRIAL IDENTIFIES CELL POPULATIONS ASSOCIATED WITH RESPONSE TO RITUXIMAB AND TOCILIZUMAB. Elsevier  Annals of the Rheumatic Diseases  vol. 81, (Suppl 1) 56.2-5657.  

(2022). RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients. Springer Nature  Scientific Data  vol. 9, (1)  

Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L, Emery P, Ng WF, Sutcliffe N, Everett C, Fernandez C, Tappuni A, Lewis M, Pitzalis C, Bowman SJ and Bombardieri M (2021). OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL. Annals of the Rheumatic Diseases  vol. 80, (Suppl 1) 79-80.  

Pontarini E, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Fossati-Jimack L, Coleby R, Chowdhury F, Calcaterra F, Tappuni A, Lewis MJ, Fabris M, Quartuccio L, Della Bella S, Bowman S, Pitzalis C, Mavilio D, De Vita S and Bombardieri M (2021). NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment. Frontiers  Frontiers in Immunology  vol. 12,  

Rivellese F, Pontarini E, Fossati-Jimack L, Moura RA, Romão VC, Fonseca JE, Nerviani A, Cubuk C, Goldmann K, Bombardieri M, Lewis M and Pitzalis C (2021). OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE. Elsevier  Annals of the Rheumatic Diseases  vol. 80, (Suppl 1) 7.2-7.7.  

Ferrari M, Onuoha SC, Fossati-Jimack L, Nerviani A, Alves PL, Pagani S, Deantonio C, Colombo F, Santoro C, Sblattero D and Pitzalis C (2021). Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis. Frontiers in Immunology  vol. 12,  

Humby F, Durez P, Buch MH, Lewis MJ, Rizvi H, Rivellese F, Nerviani A, Giorli G, Mahto A, Montecucco C, Lauwerys B, Ng N, Ho P, Bombardieri M, Romão VC, Verschueren P, Kelly S, Sainaghi PP, Gendi N, Dasgupta B, Cauli A, Reynolds P, Cañete JD, Moots R, Taylor PC, Edwards CJ, Isaacs J, Sasieni P, Choy E and Pitzalis C (2021). Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial. Elsevier  The Lancet  vol. 397, (10271) 305-317.  

Pontarini E, Murray-Brown WJ, Croia C, Lucchesi D, Conway J, Rivellese F, Fossati-Jimack L, Astorri E, Prediletto E, Corsiero E, Delvecchio FR, Coleby R, Gelbhardt E, Bono A, Baldini C, Puxeddu I, Ruscitti P, Giacomelli R, Barone F, Fisher B, Bowman SJ, Colafrancesco S, Priori R, Sutcliffe N, Challacombe S, Carlesso G, Tappuni A, Pitzalis C and Bombardieri M (2020). Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma. Elsevier  Annals of the Rheumatic Diseases  vol. 79, (12) 1588-1599.  

Jackson WD, Gulino A, Fossati-Jimack L, Seoane RC, Tian K, Best K, Köhl J, Belmonte B, Strid J and Botto M (2020). C3 Drives Inflammatory Skin Carcinogenesis Independently of C5. Elsevier  Journal of Investigative Dermatology  vol. 141, (Immunobiology 209 7 ) 404-414.e6.  

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands R, Giorli G, Frias B, Thornborn G, Jaworska E, John C, Goldmann K, Lewis M, Manzo A, Bombardieri M, Pitzalis C, investigators P and investigators R (2020). P233 B cell-rich synovitis in early and established rheumatoid arthritis. Rheumatology  vol. 59, (Supplement_2)  

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C and PEAC- R4RA investigators (2020). B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure. Wiley  Arthritis and Rheumatology   

El Shikh MEM, El Sayed R, Nerviani A, Goldmann K, John CR, Hands R, Fossati-Jimack L, Lewis MJ and Pitzalis C (2019). Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis. Elsevier BV  Journal of Autoimmunity   

Pontarini E, Lucchesi D, Fossati-Jimack L, Coleby R, Tentorio P, Croia C, Bombardieri M and Mavilio D (2018). NK cell recruitment in salivary glands provides early viral control but is dispensable for tertiary lymphoid structure formation. Oxford University Press (OUP)  Journal of Leukocyte Biology  vol. 105, (3) 589-602.  

Cope AP, Barnes MR, Belson A, Binks M, Brockbank S, Bonachela-Capdevila F, Carini C, Fisher BA, Goodyear CS, Emery P, Ehrenstein MR, Gozzard N, Harris R, Hollis S, Keidel S, Levesque M, Lindholm C, McDermott MF, McInnes IB, Mela CM, Parker G, Read S, Pedersen AW, Ponchel F, Porter D, Rao R, Rowe A, Schulz-Knappe P, Sleeman MA and Symmons D (2018). The RA-MAP Consortium: a working model for academia-industry collaboration. Nat Rev Rheumatol  vol. 14, (1) 53-60.  

Rivellese F, Mauro D, Nerviani A, Pagani S, Fossati-Jimack L, Messemaker T, Kurreeman FAS, Toes REM, Ramming A, Rauber S, Schett G, Jones GW, Jones SA, Rossi FW, de Paulis A, Marone G, Shikh MEME, Humby F and Pitzalis C (2018). Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production. Elsevier  Annals of the Rheumatic Diseases  vol. 77, (12)  

Barbour TD, Ling GS, Ruseva MM, Fossati-Jimack L, Cook HT, Botto M and Pickering MC (2016). Complement receptor 3 mediates renal protection in experimental C3 glomerulopathy. Elsevier  Kidney International  vol. 89, (4) 823-832.  

Saja MF, Baudino L, Jackson WD, Cook HT, Malik TH, Fossati-Jimack L, Ruseva M, Pickering MC, Woollard KJ and Botto M (2015). Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low Monocytes. Elsevier  Cell Reports  vol. 12, (11) 1802-1815.  

Fossati-Jimack L, Ling GS, Baudino L, Szajna M, Manivannan K, Zhao JC, Midgley R, Chai J-G, Simpson E, Botto M and Scott D (2014). Intranasal peptide‐induced tolerance and linked suppression: consequences of complement deficiency. Wiley  Immunology  vol. 144, (1) 149-157.  

Banda NK, Mehta G, Chao Y, Wang G, Inturi S, Fossati-Jimack L, Botto M, Wu L, Moghimi SM and Simberg D (2014). Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum. Springer Nature  Particle and Fibre Toxicology  vol. 11, (1)  

Sattler S, Ling G-S, Xu D, Hussaarts L, Romaine A, Zhao H, Fossati-Jimack L, Malik T, Cook HT, Botto M, Lau Y-L, Smits HH, Liew FY and Huang F-P (2014). IL-10-producing regulatory B cells induced by IL-33 (BregIL-33) effectively attenuate mucosal inflammatory responses in the gut. Elsevier  Journal of Autoimmunity  vol. 50, (100) 107-122.  

Baudino L, Sardini A, Ruseva MM, Fossati-Jimack L, Cook HT, Scott D, Simpson E and Botto M (2014). C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens. Proceedings of the National Academy of Sciences  Proceedings of the National Academy of Sciences of the United States of America  vol. 111, (4) 1503-1508.  

Ling GS, Bennett J, Woollard KJ, Szajna M, Fossati-Jimack L, Taylor PR, Scott D, Franzoso G, Cook HT and Botto M (2014). Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages. Springer Nature  Nature Communications  vol. 5, (1)  

Fossati-Jimack L, Ling GS, Cortini A, Szajna M, Malik TH, McDonald JU, Pickering MC, Cook HT, Taylor PR and Botto M (2013). Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells. Public Library of Science (PLoS)  PLOS ONE  vol. 8, (2)  

Lewis MJ, Malik TH, Fossati‐Jimack L, Carassiti D, Cook HT, Haskard DO and Botto M (2012). Distinct roles for complement in glomerulonephritis and atherosclerosis revealed in mice with a combination of lupus and hyperlipidemia. Wiley  Arthritis & Rheumatism  vol. 64, (8) 2707-2718.  

Tarzi RM, Sharp PEH, McDaid JP, Fossati-Jimack L, Herbert PE, Pusey CD, Cook HT and Warrens AN (2011). Mice with defective Fas ligand are protected from crescentic glomerulonephritis. Elsevier  Kidney International  vol. 81, (2) 170-178.  

McDonald JU, Cortini A, Rosas M, Fossati‐Jimack L, Ling GS, Lewis KJ, Dewitt S, Liddiard K, Brown GD, Jones SA, Hallett MB, Botto M and Taylor PR (2011). In vivo functional analysis and genetic modification of in vitro‐derived mouse neutrophils. Wiley  The FASEB Journal  vol. 25, (6) 1972-1982.  

Carlucci F, Fossati-Jimack L, Dumitriu IE, Heidari Y, Walport MJ, Szajna M, Baruah P, Garden OA, Cook HT and Botto M (2010). Identification and Characterization of a Lupus Suppressor 129 Locus on Chromosome 3. The American Association of Immunologists  The Journal of Immunology  vol. 184, (11) 6256-6265.  

Santiago-Raber M-L, Amano H, Amano E, Fossati-Jimack L, Swee LK, Rolink A and Izui S (2010). Evidence that Yaa-induced loss of marginal zone B cells is a result of dendritic cell-mediated enhanced activation. Elsevier  Journal of Autoimmunity  vol. 34, (4) 349-355.  

Heidari Y, Fossati-Jimack L, Carlucci F, Walport MJ, Cook HT and Botto M (2008). A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice. Springer Nature  Genes & Immunity  vol. 10, (1) 47-55.  

Baudino L, Yoshinobu K, Morito N, Kikuchi S, Fossati-Jimack L, Morley BJ, Vyse TJ, Hirose S, Jørgensen TN, Tucker RM, Roark CL, Kotzin BL, Evans LH and Izui S (2008). Dissection of Genetic Mechanisms Governing the Expression of Serum Retroviral gp70 Implicated in Murine Lupus Nephritis. The American Association of Immunologists  The Journal of Immunology  vol. 181, (4) 2846-2854.  

Fossati L, Merino J and Izui S (2008). CD4+ T cells play a major role for IgM and IgG anti-DNA production in mice infected with Plasmodium yoelii. Oxford University Press (OUP)  Clinical & Experimental Immunology  vol. 79, (2) 291-296.  

Fossati‐Jimack L, Cortes‐Hernandez J, Norsworthy PJ, Cook HT, Walport MJ and Botto M (2008). Regulation of B cell tolerance by 129‐derived chromosome 1 loci in C57BL/6 mice. Wiley  Arthritis & Rheumatism  vol. 58, (7) 2131-2141.  

Fossati-Jimack L, Cortes-Hernandez J, Norsworthy PJ, Walport MJ, Cook HT and Botto M (2007). C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice. Elsevier  Molecular Immunology  vol. 45, (3) 787-795.  

Baudino L, Fossati-Jimack L, Chevalley C, Martinez-Soria E, Shulman MJ and Izui S (2007). IgM and IgA anti-erythrocyte autoantibodies induce anemia in a mouse model through multivalency-dependent hemagglutination but not through complement activation. American Society of Hematology  Blood  vol. 109, (12) 5355-5362.  

Carlucci F, Cortes-Hernandez J, Fossati-Jimack L, Bygrave AE, Walport MJ, Vyse TJ, Cook HT and Botto M (2007). Genetic Dissection of Spontaneous Autoimmunity Driven by 129-Derived Chromosome 1 Loci When Expressed on C57BL/6 Mice. The American Association of Immunologists  The Journal of Immunology  vol. 178, (4) 2352-2360.  

Kikuchi S, Santiago-Raber M-L, Amano H, Amano E, Fossati-Jimack L, Moll T, Kotzin BL and Izui S (2006). Contribution of NZB Autoimmunity 2 to Y-Linked Autoimmune Acceleration-Induced Monocytosis in Association with Murine Systemic Lupus. The American Association of Immunologists  The Journal of Immunology  vol. 176, (5) 3240-3247.  

Trendelenburg M, Fossati-Jimack L, Cortes-Hernandez J, Turnberg D, Lewis M, Izui S, Cook HT and Botto M (2005). The Role of Complement in Cryoglobulin-Induced Immune Complex Glomerulonephritis. The American Association of Immunologists  The Journal of Immunology  vol. 175, (10) 6909-6914.  

Amano H, Amano E, Santiago‐Raber M, Moll T, Martinez‐Soria E, Fossati‐Jimack L, Iwamoto M, Rozzo SJ, Kotzin BL and Izui S (2005). Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus. Wiley  Arthritis & Rheumatism  vol. 52, (9) 2790-2798.  

Tas SW, Quartier P, Botto M and Fossati-Jimack L (2005). Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells. Elsevier  Annals of the Rheumatic Diseases  vol. 65, (2)  

Kikuchi S, Amano H, Amano E, Fossati-Jimack L, Santiago-Raber M-L, Moll T, Ida A, Kotzin BL and Izui S (2005). Identification of 2 major loci linked to autoimmune hemolytic anemia in NZB mice. American Society of Hematology  Blood  vol. 106, (4) 1323-1329.  

Kikuchi S, Fossati-Jimack L, Moll T, Amano H, Amano E, Ida A, Ibnou-Zekri N, Laporte C, Santiago-Raber M-L, Rozzo SJ, Kotzin BL and Izui S (2005). Differential Role of Three Major New Zealand Black-Derived Loci Linked with Yaa-Induced Murine Lupus Nephritis. The American Association of Immunologists  The Journal of Immunology  vol. 174, (2) 1111-1117.  

Cortes‐Hernandez J, Fossati‐Jimack L, Petry F, Loos M, Izui S, Walport MJ, Cook HT and Botto M (2004). Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice. Wiley  European Journal of Immunology  vol. 34, (12) 3713-3722.  

Haywood MEK, Rogers NJ, Rose SJ, Boyle J, McDermott A, Rankin JM, Thiruudaian V, Lewis MR, Fossati-Jimack L, Izui S, Walport MJ and Morley BJ (2004). Dissection of BXSB Lupus Phenotype Using Mice Congenic for Chromosome 1 Demonstrates That Separate Intervals Direct Different Aspects of Disease. The American Association of Immunologists  The Journal of Immunology  vol. 173, (7) 4277-4285.  

Trendelenburg M, Manderson AP, Fossati‐Jimack L, Walport MJ and Botto M (2004). Monocytosis and accelerated activation of lymphocytes in C1q‐deficient autoimmune‐prone mice. Wiley  Immunology  vol. 113, (1) 80-88.  

LEE NJ, RIGBY RJ, GILL H, BOYLE JJ, FOSSATI-JIMACK L, MORLEY BJ and VYSE TJ (2004). Multiple loci are linked with anti-red blood cell antibody production in NZB mice−comparison with other phenotypes implies complex modes of action. Oxford University Press (OUP)  Clinical & Experimental Immunology  vol. 138, (1) 39-46.  

Kuroki A, Moll T, López‐Hoyos M, Fossati‐Jimack L, Ibnou‐Zekri N, Kikuchi S, Merino J, Merino R and Izui S (2004). Enforced Bcl‐2 expression in B lymphocytes induces rheumatoid factor and anti‐DNA production, but the Yaa mutation promotes only anti‐DNA production. Wiley  European Journal of Immunology  vol. 34, (4) 1077-1084.  

Norsworthy PJ, Fossati-Jimack L, Cortes-Hernandez J, Taylor PR, Bygrave AE, Thompson RD, Nourshargh S, Walport MJ and Botto M (2004). Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol  vol. 172, (6) 3406-3414.  

Lajaunias F, Ida A, Kikuchi S, Fossati‐Jimack L, Martinez‐Soria E, Moll T, Law C and Izui S (2003). Differential control of CD22 ligand expression on B and T lymphocytes, and enhanced expression in murine systemic lupus. Wiley  Arthritis & Rheumatism  vol. 48, (6) 1612-1621.  

Tarzi RM, Davies KA, Robson MG, Fossati-Jimack L, Saito T, Walport MJ and Cook HT (2002). Nephrotoxic nephritis is mediated by Fcγ receptors on circulating leukocytes and not intrinsic renal cells. Elsevier  Kidney International  vol. 62, (6) 2087-2096.  

CORTES-HERNANDEZ J, FOSSATI-JIMACK L, CARUGATI A, POTTER PK, WALPORT MJ, COOK HT and BOTTO M (2002). Murine glomerular mesangial cell uptake of apoptotic cells is inefficient and involves serum-mediated but complement-independent mechanisms. Oxford University Press (OUP)  Clinical & Experimental Immunology  vol. 130, (3) 459-466.  

Kikuchi S, Pastore Y, Fossati-Jimack L, Kuroki A, Yoshida H, Fulpius T, Araki K, Takahashi S, Lemoine R, Reininger L and Izui S (2002). A Transgenic Mouse Model of Autoimmune Glomerulonephritis and Necrotizing Arteritis Associated with Cryoglobulinemia. The American Association of Immunologists  The Journal of Immunology  vol. 169, (8) 4644-4650.  

Kuroki A, Kuroda Y, Kikuchi S, Lajaunias F, Fulpius T, Pastore Y, Fossati-Jimack L, Reininger L, Toda T, Nakata M, Kojima N, Mizuochi T and Izui S (2002). Level of galactosylation determines cryoglobulin activity of murine IgG3 monoclonal rheumatoid factor. American Society of Hematology  Blood  vol. 99, (8) 2922-2928.  

da Silveira SA, Kikuchi S, Fossati-Jimack L, Moll T, Saito T, Verbeek JS, Botto M, Walport MJ, Carroll M and Izui S (2002). Complement Activation Selectively Potentiates the Pathogenicity of the IgG2b and IgG3 Isotypes of a High Affinity Anti-Erythrocyte Autoantibody. Rockefeller University Press  Journal of Experimental Medicine  vol. 195, (6) 665-672.  

Mitchell DA, Pickering MC, Warren J, Fossati-Jimack L, Cortes-Hernandez J, Cook HT, Botto M and Walport MJ (2002). C1q Deficiency and Autoimmunity: The Effects of Genetic Background on Disease Expression. The American Association of Immunologists  The Journal of Immunology  vol. 168, (5) 2538-2543.  

Fossati-Jimack L, da Silveira SA, Moll T, Kina T, Kuypers FA, Oldenborg P-A, Reininger L and Izui S (2002). Selective Increase of Autoimmune Epitope Expression on Aged Erythrocytes in Mice: Implications in Anti-erythrocyte Autoimmune Responses. Elsevier  Journal of Autoimmunity  vol. 18, (1) 17-25.  

Izui S, Fossati-Jimack L, Azeredo da Silveira S and Moll T (2001). Isotype-dependent pathogenicity of autoantibodies: analysis in experimental autoimmune hemolytic anemia. Springer Nature  Seminars in Immunopathology  vol. 23, (4) 433-445.  

Mizuochi T, Pastore Y, Shikata K, Kuroki A, Kikuchi S, Fulpius T, Nakata M, Fossati-Jimack L, Reininger L, Matsushita M, Fujita T and Izui S (2001). Role of galactosylation in the renal pathogenicity of murine immunoglobulin G3 monoclonal cryoglobulins. American Society of Hematology  Blood  vol. 97, (11) 3537-3543.  

Chicheportiche Y, Fossati-Jimack L, Moll S, Ibnou-Zekri N and Izui S (2000). Down-Regulated Expression of TWEAK mRNA in Acute and Chronic Inflammatory Pathologies. Elsevier  Biochemical and Biophysical Research Communications  vol. 279, (1) 162-165.  

Fossati-Jimack L, Ioan-Facsinay A, Reininger L, Chicheportiche Y, Watanabe N, Saito T, Hofhuis FMA, Gessner JE, Schiller C, Schmidt RE, Honjo T, Verbeek JS and Izui S (2000). Markedly Different Pathogenicity of Four Immunoglobulin G Isotype-Switch Variants of an Antierythrocyte Autoantibody Is Based on Their Capacity to Interact in Vivo with the Low-Affinity Fcγ Receptor III. Rockefeller University Press  Journal of Experimental Medicine  vol. 191, (8) 1293-1302.  

Hügin AW, Fossati-Jimack L and Izui S (2000). The Autoimmune Accelerating Yaa Mutation Does Not Accelerate Murine AIDS. Elsevier  Cellular Immunology  vol. 200, (2) 76-80.  

Izui S, Ibnou-Zekri N, Fossati-jimack L and Iwamoto M (2000). Lessons from BXSB and Related Mouse Models. Taylor & Francis  International Reviews of Immunology  vol. 19, (4-5) 447-472.  

Fossati-Jimack L, Reininger L, Chicheportiche Y, Clynes R, Ravetch JV, Honjo T and Izui S (1999). High Pathogenic Potential of Low-Affinity Autoantibodies in Experimental Autoimmune Hemolytic Anemia. Rockefeller University Press  Journal of Experimental Medicine  vol. 190, (11) 1689-1696.  

Ibnou-Zekri N, Iwamoto M, Fossati L, McConahey PJ and Izui S (1997). Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice. Proceedings of the National Academy of Sciences  Proceedings of the National Academy of Sciences of the United States of America  vol. 94, (26) 14654-14659.  

Santiago M-L, Fossati L, Jacquet C, Müller W, Izui S and Reininger L (1997). Interleukin-4 Protects against a Genetically Linked Lupus-like Autoimmune Syndrome. Rockefeller University Press  Journal of Experimental Medicine  vol. 185, (1) 65-70.  

Takahashi S, Fossati L, Iwamoto M, Merino R, Motta R, Kobayakawa T and Izui S (1996). Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. American Society for Clinical Investigation  Journal of Clinical Investigation  vol. 97, (7) 1597-1604.  

Fossati L, Sobel ES, Iwamoto M, Cohen PL, Eisenberg RA and Izui S (1995). The Yaa gene‐mediated acceleration of murine lupus: Yaa− T cells from non‐autoimmune mice collaborate with Yaa+ B cells to produce lupus autoantibodies in vivo. Wiley  European Journal of Immunology  vol. 25, (12) 3412-3417.  

Moll S, Menoud P-A, Fulpius T, Pastore Y, Takahashi S, Fossati L, Vassalli J-D, Sappino A-P, Schifferli JA and Izui S (1995). Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis. Elsevier  Kidney International  vol. 48, (5) 1459-1468.  

IZUI S, IWAMOTO M, FOSSATI U, MERINO R, TAKAHASHI S and IBNOU‐ZEKRI N (1995). The Yaa Gene Model of Systemic Lupus Erythematosus. Wiley  Immunological Reviews  vol. 144, (1) 137-156.  

Merino R, Fossati L, to MI, Takahashi S, Lemoine R, Ibnou-Zekri N, Pugliatti L, Merino J and Izui S (1995). Effect of Long-Term Anti-CD4 or Anti-CD8 Treatment on the Development oflprCD4−CD8−Double Negative T Cells and of the Autoimmune Syndrome in MRL-lpr/lprMice. Elsevier  Journal of Autoimmunity  vol. 8, (1) 33-45.  

Fossati L, Iwamoto M, Merino R and Izui S (1995). Selective enhancing effect of the Yaa gene on immune responses against self and foreign antigens. Wiley  European Journal of Immunology  vol. 25, (1) 166-173.  

Izui S, Merino R, Iwamoto M and Fossati L (1994). Mechanisms of genetic control of murine systemic lupus erythematosus. Springer Nature  Seminars in Immunopathology  vol. 16, (2-3) 133-152.  

Herrera PL, Harlan DM, Fossati L, Izui S, Huarte J, Orci L, Vassalli JD and Vassalli P (1994). A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice. Springer Nature  Diabetologia  vol. 37, (12) 1277-1279.  

Fossati L, Merino R, Iwamoto M, Lemoine R and Izui S (1994). Lack of association of Vβ8+ T cells with lupus‐like syndrome in MRL‐lpr/lpr mice. Wiley  European Journal of Immunology  vol. 24, (7) 1717-1720.  

Izui S, Merino R, Fossati L and Iwamoto M (1994). The Role of the Yaa Gene in Lupus Syndrome. Taylor & Francis  International Reviews of Immunology  vol. 11, (3) 211-230.  

IZUI S, BERNEY T, SHIBATA T, FULPIUS T, FOSSATI L and MERINO R (1994). Molecular and Cellular Basis for Pathogenicity of Autoantibodies. Tohoku University Medical Press  The Tohoku Journal of Experimental Medicine  vol. 173, (1)  

Merino R, Iwamoto M, Fossati L, Muniesa P, Araki K, Takahashi S, Huarte J, Yamamura K, Vassalli JD and Izui S (1993). Prevention of systemic lupus erythematosus in autoimmune BXSB mice by a transgene encoding I-E alpha chain. Rockefeller University Press  Journal of Experimental Medicine  vol. 178, (4) 1189-1197.  

Fossati L, Takahashi S, Merino R, Iwamoto M, Aubry J-P, Nose M, Spach C, Motta R and Izui S (1993). An MRL/MpJ-lpr/lpr substrain with a limited expansion of lpr double-negative T cells and a reduced autoimmune syndrome. Oxford University Press (OUP)  International Immunology  vol. 5, (5) 525-532.  

Merino R, Fossati L and Izui S (1992). The lupus-prone BXSB strain: the Yaa gene model of systemic lupus erythematosus. Springer Nature  Seminars in Immunopathology  vol. 14, (2) 141-157.  

Cerny A, Merino R, Fossati L, de Kossodo S, Heusser C, Waldvogel FA, Morse HC and Izui S (1992). Effect of Cyclosporin A and Zidovudine on Immune Abnormalities Observed in the Murine Acquired Immunodeficiency Syndrome. Oxford University Press (OUP)  The Journal of Infectious Diseases  vol. 166, (2) 285-290.  

Merino R, Fossati L, Lacour M, Lemoine R, Higaki M and Izui S (1992). H‐2‐linked control of the Yaa gene‐induced acceleration of lupus‐like autoimmune disease in BXSB mice. Wiley  European Journal of Immunology  vol. 22, (2) 295-299.  

Merino R, Fossati L, Lacour M and Izui S (1991). Selective autoantibody production by Yaa+ B cells in autoimmune Yaa(+)-Yaa- bone marrow chimeric mice. Rockefeller University Press  Journal of Experimental Medicine  vol. 174, (5) 1023-1029.  

Reininger L, Shibata T, Schurmans S, Merino R, Fossati L, Lacour M and Izui S (1990). Spontaneous production of anti‐mouse red blood cell autoantibodies is independent of the polyclonal activation in NZB mice. Wiley  European Journal of Immunology  vol. 20, (11) 2405-2410.