Prof Paul Evans

Paul Evans

Professor of Vascular Metabolism

The William Harvey Research Institute
Queen Mary University of London
07825 611695
www.paulevanslab.com/
ORCID Google Scholar X

Research

shear stress, endothelial, atherosclerosis

Cardiovascular Models

Interests

The Evans Lab focusses on the intricate biology of endothelial cells, the vital lining of blood vessels. Our primary focus lies in unraveling the mechanisms by which these cells react to the mechanical forces induced by the circulation of blood. Specifically, we use in vitro flow systems to explore the connection between endothelial responses to shear stress and the development of atherosclerosis. This disease, responsible for heart attacks and strokes, stands as a significant contributor to mortality and disability.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2024

Bowley G, Irving S, Hoefer I, Wilkinson R, Pasterkamp G, Darwish HMS, White S, Francis SE, Chico T, Noel E, Serbanovic-Canic J and Evans PC (2024). Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation. Springer Nature  Scientific Reports  vol. 14, (1)  
Boldock L, Inzoli A, Bonardelli S, Hsiao S, Marzo A, Narracott A, Gunn J, Dubini G, Chiastra C, Halliday I, Morris PD, Evans PC and C M P (2024). Correction: Integrating particle tracking with computational fluid dynamics to assess haemodynamic perturbation by coronary artery stents. Public Library of Science (PLoS)  PLOS ONE  vol. 19, (11)  
Zhou Z, Korteland S-A, Tardajos-Ayllon B, Wu J, Chambers E, Weninck J, Simons M, Dunning M, Schenkel T, Diagbouga M, Wentzel J, Fragiadaki M and Evans PC (2024). Shear stress is uncoupled from atheroprotective KLK10 in atherosclerotic plaques. Elsevier  Atherosclerosis  vol. 398,  
Pirri D, Tian S, Tardajos-Ayllon B, Irving SE, Donati F, Allen SP, Mammoto T, Vilahur G, Kabir L, Bennett J, Rasool Y, Pericleous C, Mazzei G, McAllan L, Scott WR, Koestler T, Zingg U, Birdsey GM, Miller CL, Schenkel T, Chambers EV, Dunning MJ, Serbanovic-Canic J, Botrè F, Mammoto A, Xu S, Osto E, Han W, Fragiadaki M and Evans PC (2024). EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid Uptake. Wolters Kluwer  Circulation Research  vol. 135, (8) 822-837.  
X S, Aitken C, Mehta V, Tardajos-Ayllon B, Serbanovic-Canic J, Zhu J, Miao B, Tzima E, Evans P, Fang Y and Schwartz MA (2024). Controversy in mechanotransduction – the role of endothelial cell–cell junctions in fluid shear stress sensing. The Company of Biologists  Journal of Cell Science  vol. 137, (17)  
Zhao Y, Wang L, Huang Y, Evans PC, Little PJ, Tian X, Weng J and Xu S (2024). Anthocyanins in Vascular Health and Disease: Mechanisms of Action and Therapeutic Potential. Wolters Kluwer  Journal of Cardiovascular Pharmacology  vol. 84, (3) 289-302.  
Tian S and Evans PC (2024). BMPER regulates arterial adaptation to flow. Springer Nature  Nature Cardiovascular Research  vol. 3, (7) 777-779.  
Xu M-Y, Xu J-J, Kang L-J, Liu Z-H, Su M-M, Zhao W-Q, Wang Z-H, Sun L, Xiao J-B, Evans PC, Tian X-Y, Wang L, Huang Y, Liang X-M, Weng J-P and Xu S-W (2024). Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice. Springer Nature  Acta Pharmacologica Sinica  vol. 45, (11) 2277-2289.  
Wentzel JJ, Bos D, White SJ, van der Heiden K, Kavousi M and Evans PC (2024). Sex-related differences in coronary and carotid vessel geometry, plaque composition and shear stress obtained from imaging. Elsevier  Atherosclerosis  vol. 395,  
Wagner R, Carré MJ, Perrault CM, Evans PC and Lewis R (2024). Assessing friction and damage of cell monolayers on soft substrates in vitro. The Royal Society  Journal of The Royal Society Interface  vol. 21, (215)  
Wei S, Wang L, Evans PC and Xu S (2024). NAFLD and NASH: etiology, targets and emerging therapies. Elsevier  Drug Discovery Today  vol. 29, (3)  

2023

Evans PC and Pearson J (2023). Editorial overview: Recent insights into the multifaceted physiology of the endothelial cell and its modulated functions in pathology. Elsevier  Current Opinion in Physiology  vol. 36,  
Alfaidi M, Evans PC and Pickering JG (2023). Editorial: Endothelial-to-mesenchymal transition in cardiovascular disease. Frontiers  Frontiers in Cardiovascular Medicine  vol. 10,  
(2023). Correction to: EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 43, (6) e230-e230.  
Li X, Souilhol C, Canham L, Jia X, Diagbouga M, Ayllon BT, Serbanovic-Canic J and Evans PC (2023). DLL4 promotes partial endothelial-to-mesenchymal transition at atherosclerosis-prone regions of arteries. Elsevier  Vascular Pharmacology  vol. 150,  
Canham L, Sendac S, Diagbouga MR, Wolodimeroff E, Pirri D, Ayllon BT, Feng S, Souilhol C, Chico TJA, Evans PC and Serbanovic-Canic J (2023). EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 43, (4) 547-561.  

2022

de Winther MPJ, Bäck M, Evans P, Gomez D, Goncalves I, Jørgensen HF, Koenen RR, Lutgens E, Norata GD, Osto E, Dib L, Simons M, Stellos K, Ylä-Herttuala S, Winkels H, Bochaton-Piallat M-L and Monaco C (2022). Translational opportunities of single-cell biology in atherosclerosis. Oxford University Press (OUP)  European Heart Journal  vol. 44, (14) 1216-1230.  
Souilhol C, Ayllon BT, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D, Chambers EV, Dunning MJ, Ariaans M, Li J, Fang Y, Jørgensen HF, Simons M, Krams R, Waltenberger J, Fragiadaki M, Ridger V, De Val S, Francis SE, Chico TJA, Serbanovic-Canic J and Evans PC (2022). JAG1-NOTCH4 mechanosensing drives atherosclerosis. American Association for the Advancement of Science  Science Advances  vol. 8, (35)  
Evans PC, Davidson SM, Wojta J, Bäck M, Bollini S, Brittan M, Catapano AL, Chaudhry B, Cluitmans M, Gnecchi M, Guzik TJ, Hoefer I, Madonna R, Monteiro JP, Morawietz H, Osto E, Padró T, Sluimer JC, Tocchetti CG, Van der Heiden K, Vilahur G, Waltenberger J and Weber C (2022). From novel discovery tools and biomarkers to precision medicine—basic cardiovascular science highlights of 2021/22. Oxford University Press (OUP)  Cardiovascular Research  vol. 118, (13) 2754-2767.  
Boldock L, Inzoli A, Bonardelli S, Hsiao S, Marzo A, Narracott A, Gunn J, Dubini G, Chiastra C, Halliday I, Morris PD, Evans PC and C M P (2022). Integrating particle tracking with computational fluid dynamics to assess haemodynamic perturbation by coronary artery stents. Public Library of Science (PLoS)  PLOS ONE  vol. 17, (7)  
Arbustini E, Behr ER, Carrier L, van Duijn C, Evans P, Favalli V, van der Harst P, Haugaa KH, Jondeau G, Kääb S, Kaski JP, Kavousi M, Loeys B, Pantazis A, Pinto Y, Schunkert H, Di Toro A, Thum T, Urtis M, Waltenberger J and Elliott P (2022). Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics. Oxford University Press (OUP)  European Heart Journal  vol. 43, (20) 1901-1916.  
Chen Y, Evans PC and Wilkinson RN (2022). A Workflow to Track and Analyze Endothelial Migration During Vascular Development in Zebrafish Embryos Using Lightsheet Microscopy. Angiogenesis  Springer Nature   

2021

Iqbal J, Chamberlain J, Alfaidi M, Hughes M, Alizadeh T, Casbolt H, Evans P, Mann B, Motterlini R, Francis S and Gunn J (2021). Carbon Monoxide Releasing Molecule A1 Reduces Myocardial Damage After Acute Myocardial Infarction in a Porcine Model. Wolters Kluwer  Journal of Cardiovascular Pharmacology  vol. 78, (5) e656-e661.  
Chiva-Blanch G and Evans PC (2021). Scientists on the Spot: A matter of blood flow. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (12) e162-e163.  
Bowley G, Chico TJ, Serbanovic-Canic J and Evans PC (2021). Quantifying endothelial cell proliferation in the zebrafish embryo. F1000Research  F1000Research  vol. 10,  
Nataraj R, Hiwarkar P, Bonney D, Campbell H, Jones S, Deambrosis D, Evans P, Poulton K, van Hasselt PM, Bierings M, Boelens JJ, Lindemans CA and Wynn R (2021). B-cell depletion abrogates immune mediated cytopenia and rejection of cord blood transplantation in Hurler syndrome. Springer Nature  Bone Marrow Transplantation  vol. 57, (1) 38-42.  
Kugler E, Snodgrass R, Bowley G, Plant K, Serbanovic-Canic J, Hamilton N, Evans PC, Chico T and Armitage P (2021). The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. Bioscientifica  Vascular Biology  vol. 3, (1) 1-16.  
Davidson SM, Padró T, Bollini S, Vilahur G, Duncker DJ, Evans PC, Guzik T, Hoefer IE, Waltenberger J, Wojta J and Weber C (2021). Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (10) 2161-2174.  
Kraler S, Libby P, Evans PC, Akhmedov A, Schmiady MO, Reinehr M, Camici GG and Lüscher TF (2021). Resilience of the Internal Mammary Artery to Atherogenesis: Shifting From Risk to Resistance to Address Unmet Needs. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 41, (8) 2237-2251.  
Evans P, Wojta J, Hoefer IE, Waltenberger J, Guzik T and Badimon L (2021). Erratum to: The year in basic vascular biology research: from mechanoreceptors and neutrophil extracellular traps to smartphone data and omics. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (9) 2107-2107.  
Bowley G, Kugler E, Wilkinson R, Lawrie A, van Eeden F, Chico TJA, Evans PC, Noël ES and Serbanovic‐Canic J (2021). Zebrafish as a tractable model of human cardiovascular disease. Wiley  British Journal of Pharmacology  vol. 179, (5) 900-917.  
Ward AO, Sala-Newby GB, Ladak S, Angelini GD, Caputo M, Suleiman M-S, Evans PC, George SJ and Zakkar M (2021). Nrf2-Keap-1 imbalance under acute shear stress induces inflammatory response in venous endothelial cells. SAGE Publications  Perfusion  vol. 37, (6) 582-589.  
Evans P, Wojta J, Hoefer IE, Waltenberger J, Guzik T, Badimon L and Weber C (2021). The year in basic vascular biology research: from mechanoreceptors and neutrophil extracellular traps to smartphone data and omics. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (8) 1814-1822.  
Wagner RMF, Maiti R, Carré MJ, Perrault CM, Evans PC and Lewis R (2021). Bio-tribology of Vascular Devices: A Review of Tissue/Device Friction Research. Elsevier  Biotribology  vol. 25,  
An W, Luong LA, Bowden NP, Yang M, Wu W, Zhou X, Liu C, Niu K, Luo J, Zhang C, Sun X, Poston R, Zhang L, Evans PC and Xiao Q (2021). Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling. Oxford University Press (OUP)  Cardiovascular Research  vol. 118, (2) 638-653.  
Wang M, Murdoch CE, Brewer AC, Ivetic A, Evans P, Shah AM and Zhang M (2021). Endothelial NADPH oxidase 4 protects against angiotensin II‐induced cardiac fibrosis and inflammation. Wiley  ESC Heart Failure  vol. 8, (2) 1427-1437.  

2020

Evans PC, Fragiadaki M, Morris PD and Serbanovic-Canic J (2020). Shear stress: the dark energy of atherosclerotic plaques. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (8) 1811-1813.  
Ward AO, Angelini GD, Caputo M, Evans PC, Johnson JL, Suleiman MS, Tulloh RM, George SJ and Zakkar M (2020). NF-κB inhibition prevents acute shear stress-induced inflammation in the saphenous vein graft endothelium. Springer Nature  Scientific Reports  vol. 10, (1)  
Dweck MR, Maurovich-Horvat P, Leiner T, Cosyns B, Fayad ZA, Gijsen FJH, Van der Heiden K, Kooi ME, Maehara A, Muller JE, Newby DE, Narula J, Pontone G, Regar E, Serruys PW, van der Steen AFW, Stone PH, Waltenberger JL, Yuan C, Evans PC, Lutgens E, Wentzel JJ and Bäck M (2020). Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology and the European Association of Cardiovascular Imaging. Oxford University Press (OUP)  European Heart Journal - Cardiovascular Imaging  vol. 21, (11) 1177-1183.  
Pirri D, Fragiadaki M and Evans PC (2020). Diabetic atherosclerosis: is there a role for the hypoxia-inducible factors? Portland Press  Bioscience Reports  vol. 40, (8)  
Evans PC, Rainger GE, Mason JC, Guzik TJ, Osto E, Stamataki Z, Neil D, Hoefer IE, Fragiadaki M, Waltenberger J, Weber C, Bochaton-Piallat M-L and Bäck M (2020). Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science. Oxford University Press (OUP)  Cardiovascular Research  vol. 116, (14) 2177-2184.  
Morris PD, Gosling R, Zwierzak I, Evans H, Aubiniere-Robb L, Czechowicz K, Evans PC, Hose DR, Lawford PV, Narracott AJ and Gunn JP (2020). A novel method for measuring absolute coronary blood flow and microvascular resistance in patients with ischaemic heart disease. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (6) 1567-1577.  
Naase H, Harling L, Kidher E, Sepehripour A, Nguyen B, Kapelouzou A, Cokkinos D, Stavridis G, Angelini G, Evans PC and Athanasiou T (2020). Toll-like receptor 9 and the inflammatory response to surgical trauma and cardiopulmonary bypass. Springer Nature  Journal of Cardiothoracic Surgery  vol. 15, (1)  
Alexander Y, Osto E, Schmidt-Trucksäss A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Bäck M, Badimon L, Cosentino F, De Carlo M, Dorobantu M, Harrison DG, Guzik TJ, Hoefer I, Morris PD, Norata GD, Suades R, Taddei S, Vilahur G, Waltenberger J, Weber C, Wilkinson F, Bochaton-Piallat M-L and Evans PC (2020). Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis. Oxford University Press (OUP)  Cardiovascular Research  vol. 117, (1) 29-42.  
Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE, Van der Heiden K, Ridger V and Evans PC (2020). Author Correction: Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. Springer Nature  Scientific Reports  vol. 10, (1)  
Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L, Long M, Parry S, Woods R, Hulston C, Benedikter B, Niespolo C, Bazaz R, Francis S, Kiss-Toth E, van Zandvoort M, Schober A, Hellewell P, Evans PC and Ridger V (2020). Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Springer Nature  Nature Communications  vol. 11, (1)  

2019

Zun PS, Narracott AJ, Evans PC, van Rooij BJM and Hoekstra AG (2019). A particle-based model for endothelial cell migration under flow conditions. Springer Nature  Biomechanics and Modeling in Mechanobiology  vol. 19, (2) 681-692.  
Gijsen F, Katagiri Y, Barlis P, Bourantas C, Collet C, Coskun U, Daemen J, Dijkstra J, Edelman E, Evans P, van der Heiden K, Hose R, Koo B-K, Krams R, Marsden A, Migliavacca F, Onuma Y, Ooi A, Poon E, Samady H, Stone P, Takahashi K, Tang D, Thondapu V, Tenekecioglu E, Timmins L, Torii R, Wentzel J and Serruys P (2019). Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical applications. Oxford University Press (OUP)  European Heart Journal   
Souilhol C, Gauci I, Feng S, Ayllon BT, Mahmoud M, Canham L, Fragiadaki M, Serbanovic-Canic J, Ridger V and Evans PC (2019). Homeobox B9 integrates bone morphogenic protein 4 with inflammation at atheroprone sites. Oxford University Press (OUP)  Cardiovascular Research  vol. 116, (7) 1300-1310.  
Souilhol C, Serbanovic-Canic J, Fragiadaki M, Chico TJ, Ridger V, Roddie H and Evans PC (2019). Endothelial responses to shear stress in atherosclerosis: a novel role for developmental genes. Springer Nature  Nature Reviews Cardiology  vol. 17, (1) 52-63.  
Ketelhuth DFJ, Lutgens E, Bäck M, Binder CJ, Van den Bossche J, Daniel C, Dumitriu IE, Hoefer I, Libby P, O’Neill L, Weber C and Evans PC (2019). Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology. Oxford University Press (OUP)  Cardiovascular Research  vol. 115, (9) 1385-1392.  
Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L, Akhtar N, Feng S, Ridger V, Waltho J, Pinteaux E, Humphries MJ, Bryan MT and Evans PC (2019). β1 integrin is a sensor of blood flow direction. The Company of Biologists  Journal of Cell Science  vol. 132, (11)  
Serbanovic-Canic J, Souilhol C and Evans PC (2019). Shear stress makes its mark on the endothelial genome. Oxford University Press (OUP)  Cardiovascular Research  vol. 115, (10) 1449-1451.  
Baeriswyl DC, Prionisti I, Peach T, Tsolkas G, Chooi KY, Vardakis J, Morel S, Diagbouga MR, Bijlenga P, Cuhlmann S, Evans P, Kwak BR, Ventikos Y and Krams R (2019). Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo. Sci Rep  vol. 9, (1) 4738-4738.  
Mahmoud M, Souilhol C, Serbanovic-Canic J and Evans P (2019). GATA4-Twist1 Signalling in Disturbed Flow-Induced Atherosclerosis. Springer Nature  Cardiovascular Drugs and Therapy  vol. 33, (2) 231-237.  

2018

Fragiadaki M and Evans PC (2018). The Bernard and Joan Marshall Early Career Investigators and Distinguished Investigator Award 2018. Springer Nature  Cardiovascular Drugs and Therapy  vol. 33, (2) 203-205.  
Tuñón J, Badimón L, Bochaton-Piallat M-L, Cariou B, Daemen MJ, Egido J, Evans PC, Hoefer IE, Ketelhuth DFJ, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C and Bäck M (2018). Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. Oxford University Press (OUP)  Cardiovascular Research  vol. 115, (1) 10-19.  
Xing R, Moerman AM, Ridwan RY, Gaalen KV, Meester EJ, van der Steen AFW, Evans PC, Gijsen FJH and Van der Heiden K (2018). The effect of the heart rate lowering drug Ivabradine on hemodynamics in atherosclerotic mice. Springer Nature  Scientific Reports  vol. 8, (1)  
Caporali A, Bäck M, Daemen MJ, Hoefer IE, Jones EA, Lutgens E, Matter CM, Bochaton-Piallat M-L, Siekmann AF, Sluimer JC, Steffens S, Tuñón J, Vindis C, Wentzel JJ, Ylä-Herttuala S and Evans PC (2018). Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology. Oxford University Press (OUP)  Cardiovascular Research  vol. 114, (11) 1411-1421.  
Alfaidi MA, Chamberlain J, Rothman A, Crossman D, Villa‐Uriol M, Hadoke P, Wu J, Schenkel T, Evans PC and Francis SE (2018). Dietary Docosahexaenoic Acid Reduces Oscillatory Wall Shear Stress, Atherosclerosis, and Hypertension, Most Likely Mediated via an IL‐1–Mediated Mechanism. Wolters Kluwer  Journal of the American Heart Association  vol. 7, (13)  
Tuñón J, Bäck M, Badimón L, Bochaton-Piallat M-L, Cariou B, Daemen MJ, Egido J, Evans PC, Francis SE, Ketelhuth DF, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C and Hoefer IE (2018). Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. Oxford University Press (OUP)  European Journal of Preventive Cardiology  vol. 25, (9) 948-955.  
Souilhol C and Evans PC (2018). Notching Up Vascular Inflammation. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 38, (4) 698-699.  
Souilhol C, Harmsen MC, Evans PC and Krenning G (2018). Endothelial–mesenchymal transition in atherosclerosis. Oxford University Press (OUP)  Cardiovascular Research  vol. 114, (4) 565-577.  

2017

Feng S, Fragiadaki M, Souilhol C, Ridger V and Evans PC (2017). Response by Feng et al to Letter Regarding Article, “Mechanical Activation of Hypoxia-Inducible Factor 1&agr; Drives Endothelial Dysfunction at Atheroprone Sites”. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 37, (12) e199-e200.  
Green JP, Souilhol C, Xanthis I, Martinez-Campesino L, Bowden NP, Evans PC and Wilson HL (2017). Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling. Oxford University Press (OUP)  Cardiovascular Research  vol. 114, (2) 324-335.  
Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S, Thompson AAR, Jo H, Weber C, Ridger V, Schober A and Evans PC (2017). Mechanical Activation of Hypoxia-Inducible Factor 1&agr; Drives Endothelial Dysfunction at Atheroprone Sites. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 37, (11) 2087-2101.  
Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE, Van der Heiden K, Ridger V and Evans PC (2017). Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. Springer Nature  Scientific Reports  vol. 7, (1)  
Mann P, Khamis RY, Haskard D, Ta M, Kojima C, Ammari T, Caga-Anan M, Nguyen BA, Anderson JR, Evans PC and Johns M (2017). 169 Developing capture assays to measure circulating crp/oxidised low density lipoprotein complexes in patients undergoing cardiopulmonary bypass and examining use of crp/oxidised low density lipoprotein complexes as a biomarker of atherosclerosis. BMJ  Heart  vol. 103, (Suppl 5)  
Ridger VC, Boulanger CM, Angelillo-Scherrer A, Badimon L, Blanc-Brude O, Bochaton-Piallat M-L, Boilard E, Buzas EI, Caporali A, Dignat-George F, Evans PC, Lacroix R, Lutgens E, Ketelhuth DFJ, Nieuwland R, Toti F, Tuñon J, Weber C, Hoefer IE, Lip GYH, Werner N, Shantsila E, ten Cate H, Thomas M and Harrison P (2017). Microvesicles in vascular homeostasis and diseases. Thieme  Thrombosis and Haemostasis  vol. 117, (07) 1296-1316.  
Nguyen BA, McDonald G, Fiorentino F, Reeves BC, Kwak J, Pyo S, Angelini GD, Anderson JR, Frost G, Haskard DO and Evans PC (2017). Consumption of Broccoli Sprouts Attenuates Intracellular P38 Map Kinase and Reactive Oxygen Species Pro-Inflammatory Activation in Human Leukocytes: A Randomised- Controlled Trial. OMICS International  Journal of Clinical Nutrition & Dietetics  vol. 3, (4)  

2016

Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton J-P, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJA and Evans PC (2016). Zebrafish Model for Functional Screening of Flow-Responsive Genes. Wolters Kluwer Health, Inc  Arterioscler Thromb Vasc Biol  vol. 37, (1) 130-143.  
Nguyen B, Reeves B, Angelini G, Haskard D and Evans P (2016). Reply. Elsevier  The Annals of Thoracic Surgery  vol. 102, (5) 1765-1766.  
Hsiao ST, Spencer T, Boldock L, Prosseda SD, Xanthis I, Tovar-Lopez FJ, Van Beusekom HMM, Khamis RY, Foin N, Bowden N, Hussain A, Rothman A, Ridger V, Halliday I, Perrault C, Gunn J and Evans PC (2016). Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase. Oxford University Press (OUP)  Cardiovascular Research  vol. 112, (3) 689-701.  
Halliday I, Lishchuk SV, Spencer TJ, Pontrelli G and Evans PC (2016). Local membrane length conservation in two-dimensional vesicle simulation using a multicomponent lattice Boltzmann equation method. American Physical Society (APS)  Physical Review E  vol. 94, (2)  
Holloway PM, Gillespie S, Becker F, Vital SA, Nguyen V, Alexander JS, Evans PC and Gavins FNE (2016). Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways. Elsevier  Vascular Pharmacology  vol. 85, 29-38.  
Bowden N, Feng S, Francis S and Evans P (2016). 211 Non-Canonical NF-Κb Signalling Promotes Endothelial Proliferation in Response to Low Wall Shear Stress. BMJ  Heart  vol. 102, (Suppl 6)  
Green J, Evans P and Wilson H (2016). 191 Atheroprone Flow Alters ATP-Induced Calcium Signalling in the Endothelium. BMJ  Heart  vol. 102, (Suppl 6)  
Mahmoud MM, Kim HR, Xing R, Hsiao S, Mammoto A, Chen J, Serbanovic-Canic J, Feng S, Bowden NP, Maguire R, Ariaans M, Francis SE, Weinberg PD, van der Heiden K, Jones EA, Chico TJA, Ridger V and Evans PC (2016). TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis. Wolters Kluwer  Circulation Research  vol. 119, (3) 450-462.  
Bowden N, Bryan MT, Duckles H, Feng S, Hsiao S, Kim HR, Mahmoud M, Moers B, Serbanovic-Canic J, Xanthis I, Ridger VC and Evans PC (2016). Experimental Approaches to Study Endothelial Responses to Shear Stress. Mary Ann Liebert  Antioxidants & Redox Signaling  vol. 25, (7) 389-400.  
Brown AJ, Teng Z, Evans PC, Gillard JH, Samady H and Bennett MR (2016). Role of biomechanical forces in the natural history of coronary atherosclerosis. Springer Nature  Nature Reviews Cardiology  vol. 13, (4) 210-220.  
Luong L, Duckles H, Schenkel T, Mahmoud M, Tremoleda JL, Wylezinska-Arridge M, Ali M, Bowden NP, Villa-Uriol M-C, van der Heiden K, Xing R, Gijsen FJ, Wentzel J, Lawrie A, Feng S, Arnold N, Gsell W, Lungu A, Hose R, Spencer T, Halliday I, Ridger V and Evans PC (2016). Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries. Thieme  Thrombosis and Haemostasis  vol. 116, (01) 181-190.  
Evans PC, Gijsen FJH, Wentzel JJ and van der Heiden K (2016). Biomechanics in vascular biology and cardiovascular disease. Thieme  Thrombosis and Haemostasis  vol. 115, (03) 465-466.  
Maguire R, Duckles H, Evans PC and Chico T (2016). How does blood flow regulate vascular notch signalling? Elsevier  Atherosclerosis  vol. 244,  

2015

Nguyen BAV, Fiorentino F, Reeves BC, Baig K, Athanasiou T, Anderson JR, Haskard DO, Angelini GD and Evans PC (2015). Mini Bypass and Proinflammatory Leukocyte Activation: A Randomized Controlled Trial. Elsevier  The Annals of Thoracic Surgery  vol. 101, (4) 1454-1463.  
Morris PD, Narracott A, von Tengg-Kobligk H, Soto DAS, Hsiao S, Lungu A, Evans P, Bressloff NW, Lawford PV, Hose DR and Gunn JP (2015). Computational fluid dynamics modelling in cardiovascular medicine. BMJ  Heart  vol. 102, (1)  
Di Marco LY, Venneri A, Farkas E, Evans PC, Marzo A and Frangi AF (2015). Vascular dysfunction in the pathogenesis of Alzheimer's disease — A review of endothelium-mediated mechanisms and ensuing vicious circles. Elsevier  Neurobiology of Disease  vol. 82, 593-606.  
Hoefer IE, Steffens S, Ala-Korpela M, Bäck M, Badimon L, Bochaton-Piallat M-L, Boulanger CM, Caligiuri G, Dimmeler S, Egido J, Evans PC, Guzik T, Kwak BR, Landmesser U, Mayr M, Monaco C, Pasterkamp G, Tuñón J and Weber C (2015). Novel methodologies for biomarker discovery in atherosclerosis. Oxford University Press (OUP)  European Heart Journal  vol. 36, (39) 2635-2642.  
Green J, Wilson H and Evans P (2015). 185 Shear Stress Dependent Regulation of p2x4 and p2x7 Receptors in the Endothelium. BMJ  Heart  vol. 101, (Suppl 4)  
Alfaidi M, Schenkel T, Evans P, Chamberlain J and Francis S (2015). 192 Dietary Docosahexaenoic Acid Reduced Experimental Atherosclerosis by Inducing Protective Haemodynamic Conditions. BMJ  Heart  vol. 101, (Suppl 4)  
Gomez I, Ward B, Evans P, Hellewell P and Ridger V (2015). YIA2 Neutrophil Microvesicles Influence Atherogenesis and Contain Mirna. BMJ  Heart  vol. 101, (Suppl 4)  
Mahmoud M, Kim R, Hsiao S, Xing R, Van der Heiden K, Mammoto A, Chen J, Gauci I, Feng S and Evans P (2015). 204 Disturbed Flow Promotes Atherogenesis through the Activation of Endothelial-Mesenchymal Transition. BMJ  Heart  vol. 101, (Suppl 4)  
Gomez I, Ward B, Evans P, Hellewell P and Ridger V (2015). Abstract 558: Neutrophils-derived-microvesicle Could Play a Role in the Early Stage of Atherosclerosis. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 35, (suppl_1)  
Kidher E, Jarral OA, Harling L, Anderson JR, Chukwuemeka A, Ashrafian H, Evans PC and Athanasiou T (2015). NR2 antibody is associated with quality of life in aortic valve replacement. SAGE Publications  Asian Cardiovascular and Thoracic Annals  vol. 23, (6) 690-700.  
Mylroie H, Dumont O, Bauer A, Thornton CC, Mackey J, Calay D, Hamdulay SS, Choo JR, Boyle JJ, Samarel AM, Randi AM, Evans PC and Mason JC (2015). PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis. Oxford University Press (OUP)  Cardiovascular Research  vol. 106, (3) 509-519.  
Enesa K, Moll HP, Luong L, Ferran C and Evans PC (2015). A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes. Wiley  The FASEB Journal  vol. 29, (5) 1869-1878.  

2014

Duckles H, Mahmoud M, Hsiao S, Gauci I, Bowden N, Luong L and Evans PC (2014). Identification of a molecular switch controlling the induction of senescence or quiescence by flow. Elsevier  Atherosclerosis  vol. 237, (2)  
Bowden N, Duckles H, Mahmoud M, Hsiao S, Francis SE and Evans PC (2014). Disturbed flow induces expression of the negative NF-kappaB regulator Cezanne. Elsevier  Atherosclerosis  vol. 237, (2)  
Gauci I, Mahmoud M, Duckles H, Feng S, Hsiao S and Evans PC (2014). Disturbed flow influences endothelial activation by inducing homeobox transcription factors. Elsevier  Atherosclerosis  vol. 237, (2)  
Mahmoud M, Hsiao S, Gauci I, Kim HR and Evans PC (2014). GATA4 promotes endothelial cell turnover at regions of arteries exposed to disturbed flow. Elsevier  Atherosclerosis  vol. 237, (2) e2-e3.  
Kwak BR, Bäck M, Bochaton-Piallat M-L, Caligiuri G, Daemen MJAP, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ and Evans PC (2014). Biomechanical factors in atherosclerosis: mechanisms and clinical implications†. Oxford University Press (OUP)  European Heart Journal  vol. 35, (43) 3013-3020.  
Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow MJ, Sedo A, Hyman AJ, McKeown L, Young RS, Yuldasheva NY, Majeed Y, Wilson LA, Rode B, Bailey MA, Kim HR, Fu Z, Carter DAL, Bilton J, Imrie H, Ajuh P, Dear TN, Cubbon RM, Kearney MT, Prasad KR, Evans PC, Ainscough JFX and Beech DJ (2014). Piezo1 integration of vascular architecture with physiological force. Springer Nature  Nature  vol. 515, (7526) 279-282.  
Cuhlmann S, Gsell W, Van der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J, Davenport AP, Clark J, Haskard D, Krams R, Jones H and Evans PC (2014). In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106. SAGE Publications  Molecular Imaging  vol. 13, (6)  
Hsiao S, Tovar-Lopez F, Gunn J, Spencer T, Halliday I, Perrault C and Evans P (2014). 292Endothelial cell forward migration in a disturbed wall shear stress environment is promoted by ROCK inhibition. Oxford University Press (OUP)  Cardiovascular Research  vol. 103, (suppl_1) s53-s53.  
Bryan MT, Duckles H, Feng S, Hsiao ST, Kim HR, Serbanovic-Canic J and Evans PC (2014). Mechanoresponsive Networks Controlling Vascular Inflammation. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 34, (10) 2199-2205.  
Kidher E, Harling L, Ashrafian H, Naase H, Francis DP, Evans P and Athanasiou T (2014). Aortic stiffness as a marker of cardiac function and myocardial strain in patients undergoing aortic valve replacement. Springer Nature  Journal of Cardiothoracic Surgery  vol. 9, (1)  
Nguyen BAV, Suleiman M-S, Anderson JR, Evans PC, Fiorentino F, Reeves BC and Angelini GD (2014). Metabolic derangement and cardiac injury early after reperfusion following intermittent cross-clamp fibrillation in patients undergoing coronary artery bypass graft surgery using conventional or miniaturized cardiopulmonary bypass. Springer Nature  Molecular and Cellular Biochemistry  vol. 395, (1-2) 167-175.  
Kidher E, Harling L, Sugden C, Ashrafian H, Casula R, Evans P, Nihoyannopoulos P and Athanasiou T (2014). Aortic stiffness is an indicator of cognitive dysfunction before and after aortic valve replacement for aortic stenosis. Oxford University Press (OUP)  Interdisciplinary CardioVascular and Thoracic Surgery  vol. 19, (4) 595-604.  
Amini N, Boyle JJ, Moers B, Warboys CM, Malik TH, Zakkar M, Francis SE, Mason JC, Haskard DO and Evans PC (2014). Requirement of JNK1 for endothelial cell injury in atherogenesis. Elsevier  Atherosclerosis  vol. 235, (2) 613-618.  
Hsiao S, Tovar F, Gunn J, Spencer T, Halliday I, Perrault C and Evans P (2014). 219 Rock Inhibits Endothelial Migration in Disturbed flow Condition: A Potential Therapeutic Target in PCI. BMJ  Heart  vol. 100, (Suppl 3)  
Mahmoud M, Kim R, de Luca A, Gauci I, Hsiao S and Evans PC (2014). Abstract 266: Disturbed Flow Promotes Endothelial Cell Injury via the Induction of Developmental Genes. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 34, (suppl_1)  
Hsiao S, Tovar-Lopez F, Gunn J, Spencer T, Halliday I, Perrault C and Evans P (2014). Abstract 521: Endothelial Cell Forward Migration in a Disturbed Wall Shear Stress Environment is Promoted by Rho-Kinase Inhibition. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 34, (suppl_1)  
Luong L, Duckles H, Schenkel T, Arnold N, Gsell W, Lungu A, Spencer T, Hose R, Halliday I and Evans P (2014). Abstract 258: A Pharmacological Approach to Promote Shear Stress-Dependent Anti-inflammatory Mechanisms in Arteries. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 34, (suppl_1)  
Warboys CM, de Luca A, Amini N, Luong L, Duckles H, Hsiao S, White A, Biswas S, Khamis R, Chong CK, Cheung W-M, Sherwin SJ, Bennett MR, Gil J, Mason JC, Haskard DO and Evans PC (2014). Disturbed Flow Promotes Endothelial Senescence via a p53-Dependent Pathway. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 34, (5) 985-995.  
Nguyen B, Luong L, Naase H, Vives M, Jakaj G, Finch J, Boyle J, Mulholland JW, Kwak J-H, Pyo S, de Luca A, Athanasiou T, Angelini G, Anderson J, Haskard DO and Evans PC (2014). Sulforaphane pretreatment prevents systemic inflammation and renal injury in response to cardiopulmonary bypass. Elsevier  Journal of Thoracic and Cardiovascular Surgery  vol. 148, (2) 690-697.e3.  
Enesa K and Evans P (2014). The Biology of A20-Like Molecules. The Multiple Therapeutic Targets of A20  Springer Nature   

2013

Wells RE, Barry JD, Warrington SJ, Cuhlmann S, Evans P, Huber W, Strutt D and Zeidler MP (2013). Control of tissue morphology by Fasciclin III-mediated intercellular adhesion. The Company of Biologists  Development  vol. 140, (18) 3858-3868.  
Bovens SM, Foin N, O'Clery N, Van Der Heiden K, Cuhlmann S, Carlsen H, Barahona M, Evans PC and Krams R (2013). Shear stress and nitric oxide transport affect NFkB dynamics in endothelial cells. Oxford University Press (OUP)  European Heart Journal  vol. 34, (suppl_1)  
Evans PC and Kwak BR (2013). Biomechanical factors in cardiovascular disease. Oxford University Press (OUP)  Cardiovascular Research  vol. 99, (2) 229-231.  
Serbanovic-Canic J, de Luca A, Warboys C, Chico T and Evans P (2013). YIA4: IDENTIFICATION OF NOVEL SHEAR STRESS-RESPONSIVE REGULATORS OF ENDOTHELIAL CELL DYSFUNCTION USING THE ZEBRAFISH MODEL. BMJ  Heart  vol. 99, (suppl 2)  
De Luca A, Warboys C, Amini N, Ferreira P, Firmin D, Mason J, Sherwin S and Evans P (2013). 170 TRANSCRIPTOME PROFILING IN PORCINE ARTERIES TO IDENTIFY NOVEL SHEAR-RESPONSIVE REGULATORS OF ENDOTHELIAL CELL FATE. BMJ  Heart  vol. 99, (suppl 2)  
Van der Heiden K, Gijsen FJH, Narracott A, Hsiao S, Halliday I, Gunn J, Wentzel JJ and Evans PC (2013). The effects of stenting on shear stress: relevance to endothelial injury and repair. Oxford University Press (OUP)  Cardiovascular Research  vol. 99, (2) 269-275.  
Luong LA, Fragiadaki M, Smith J, Boyle J, Lutz J, Dean JLE, Harten S, Ashcroft M, Walmsley SR, Haskard DO, Maxwell PH, Walczak H, Pusey C and Evans PC (2013). Cezanne Regulates Inflammatory Responses to Hypoxia in Endothelial Cells by Targeting TRAF6 for Deubiquitination. Wolters Kluwer  Circulation Research  vol. 112, (12) 1583-1591.  
Gray C, Bratt D, Lees J, daCosta M, Plant K, Watson OJ, Solaymani-Kohal S, Tazzyman S, Serbanovic-Canic J, Crossman DC, Keavney BD, Haase A, McMahon K, Gering M, Roehl H, Evans PC and Chico TJA (2013). Loss of Function of Parathyroid Hormone Receptor 1 Induces Notch-Dependent Aortic Defects During Zebrafish Vascular Development. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 33, (6) 1257-1263.  
Haskard DO, Boyle JJ, Evans PC, Mason JC and Randi AM (2013). Cytoprotective Signaling and Gene Expression in Endothelial Cells and Macrophages—Lessons for Atherosclerosis. Wiley  Microcirculation  vol. 20, (3) 203-216.  

2012

Nayak A, König CS, Kishore U and Evans PC (2012). Regulation of Endothelial Activation and Vascular Inflammation by Shear Stress. Micro and Nano Flow Systems for Bioanalysis  Springer Nature   
Golubnitschaja O, Costigliola V and EPMA (2012). General Report & Recommendations in Predictive, Preventive and Personalised Medicine 2012: White Paper of the European Association for Predictive, Preventive and Personalised Medicine. Springer Nature  EPMA Journal  vol. 3, (1)  
Dumont O, Mylroie H, Bauer A, Calay D, Sperone A, Thornton C, Hamdulay SS, Ali N, Boyle JJ, Choo JR, Samarel AM, Haskard DO, Randi AM, Evans PC and Mason JC (2012). Protein kinase Cϵ activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection. Portland Press  Biochemical Journal  vol. 447, (2) 193-204.  
Boyle JJ, Christou I, Iqbal MB, Nguyen AT, Leung VWY, Evans PC, Liu Y, Johns M, Kirkham P and Haskard DO (2012). Solid-Phase Immunoglobulins IgG and IgM Activate Macrophages with Solid-Phase IgM Acting via a Novel Scavenger Receptor A Pathway. Elsevier  American Journal Of Pathology  vol. 181, (1) 347-361.  
Pfenniger A, Wong C, Sutter E, Cuhlmann S, Dunoyer-Geindre S, Mach F, Horrevoets AJ, Evans PC, Krams R and Kwak BR (2012). Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells. Elsevier  Journal of Molecular and Cellular Cardiology  vol. 53, (2) 299-309.  
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S and Schäfers M (2012). Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice. MyJove  Journal of Visualized Experiments  (59)  
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S and Schäfers M (2012). Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice. MyJove  Journal of Visualized Experiments  (59)  

2011

Boyle JJ, Johns M, Lo J, Chiodini A, Ambrose N, Evans PC, Mason JC and Haskard DO (2011). Heme Induces Heme Oxygenase 1 via Nrf2. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 31, (11) 2685-2691.  
Vossenkämper A, Marchès O, Fairclough PD, Warnes G, Stagg AJ, Lindsay JO, Evans PC, Luong LA, Croft NM, Naik S, Frankel G and MacDonald TT (2011). Inhibition of NF-kB signaling in human dendritic cells the enterpathogenic Escherichia coli effector protein NIeE. The American Association of Immunologists, Inc  J Immunol  vol. 185, 4118-4127.  
Luong LA and Evans PC (2011). Targeting Inhibitor of Apoptosis Proteins to Block Vascular Inflammation. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 31, (10) 2165-2166.  
Harling L, Warren OJ, Martin A, Kemp PR, Evans PC, Darzi A and Athanasiou T (2011). Do Miniaturized Extracorporeal Circuits Confer Significant Clinical Benefit Without Compromising Safety? A Meta-Analysis of Randomized Controlled Trials. Wolters Kluwer  ASAIO Journal  vol. 57, (3) 141-151.  
Zuluaga E, Evans P, Nesom P, Spratt T and Daniels E (2011). Technical Evaluations To Support the Decision To Reinject Produced Water. Society of Petroleum Engineers (SPE)  SPE Production & Operations  vol. 26, (02) 128-139.  
Cuhlmann S, Van der Heiden K, Saliba D, Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong LA, Mason JC, Udalova I, Gsell W, Jones H, Haskard DO, Krams R and Evans PC (2011). Disturbed Blood Flow Induces RelA Expression via c-Jun N-Terminal Kinase 1. Wolters Kluwer  Circulation Research  vol. 108, (8) 950-959.  
Evans PC (2011). The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease. Springer Nature  EPMA Journal  vol. 2, (1) 9-14.  
Warboys CM, Amini N, Luca AD and Evans PC (2011). When stress is good. Scientist  vol. 25, (2)  
Zakkar M, Luong LA, Chaudhury H, Ruud O, Punjabi PP, Anderson JR, Mullholand JW, Clements AT, Krams R, Foin N, Athanasiou T, Leen ELS, Mason JC, Haskard DO and Evans PC (2011). Dexamethasone Arterializes Venous Endothelial Cells by Inducing Mitogen-Activated Protein Kinase Phosphatase-1. Wolters Kluwer  Circulation  vol. 123, (5) 524-532.  
Gsell W, Cuhlmann S, Van der Heiden K, Tremoleda JL, Khalil M, Clark J, Bird J, Jones H, Krams R and Evans PC (2011). 18FEDAA is a more specific probe than 18FDG for imaging vascular inflammation. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  vol. 38, S210-S210.  
Warboys CM, Amini N, de Luca A and Evans PC (2011). The role of blood flow in determining the sites of atherosclerotic plaques. H1 Connect  F1000 Medicine Reports  vol. 3,  

2010

Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R, Lawford PV, Lishchuk SV, Pontrelli G, Ridger V, Spencer TJ, Ventikos Y, Walker DC and Watton PN (2010). Multi-scale interaction of particulate flow and the artery wall. Elsevier  Medical Engineering & Physics  vol. 33, (7) 840-848.  
Sperone A, Dryden NH, Birdsey GM, Madden L, Johns M, Evans PC, Mason JC, Haskard DO, Boyle JJ, Paleolog EM and Randi AM (2010). The Transcription Factor Erg Inhibits Vascular Inflammation by Repressing NF-&kgr;B Activation and Proinflammatory Gene Expression in Endothelial Cells. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 31, (1) 142-150.  
Cuhlmann S, van der Heiden K, Zakkar M, Chaudhury H, Luong LA, Mason J, Haskard DO, Carlsen H, Krams R and Evans PC (2010). YIA4 C Jun N-terminal kinase promotes endothelial activation at atherosclerosis-susceptible sites by enhancing expression of NF-κB transcription factors. BMJ  Heart  vol. 96, (17)  
Jevon M, Ansari TI, Finch J, Zakkar M, Evans PC, Shurey S, Sibbons PD, Hornick P, Haskard DO and Dorling A (2010). Smooth muscle cells in porcine vein graft intimal hyperplasia are derived from the local vessel wall. Elsevier  Cardiovascular Pathology  vol. 20, (3) e91-e94.  
van der Heiden K, Cuhlmann S, Luong LA, Zakkar M and Evans PC (2010). Role of nuclear factor κB in cardiovascular health and disease. Portland Press  Clinical Science  vol. 118, (10) 593-605.  
Hamdulay SS, Wang B, Birdsey GM, Ali F, Dumont O, Evans PC, Haskard DO, Wheeler-Jones CP and Mason JC (2010). Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. Elsevier  Free Radical Biology and Medicine  vol. 48, (8) 1013-1023.  
Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, van der Heiden K, Luong LA, Davis J, Platt A, Mason JC, Krams R, Haskard DO, Clark AR and Evans PC (2010). c-Jun N-Terminal Kinase Primes Endothelial Cells at Atheroprone Sites for Apoptosis. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 30, (3) 546-553.  
Krams R, Cuhlmann S, Foin N and Evans P (2010). Shear stress, inflammation and Atherosclerosis. Springer Nature  Artery Research  vol. 4, (2) 41-46.  

2009

Amirak E, Zakkar M, Evans PC and Kemp PR (2009). Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells. Elsevier  Biochemical and Biophysical Research Communications  vol. 391, (1) 818-823.  
Zakkar M, Van der Heiden K, Luong LA, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I, Rahman I, Carlsen H, Haskard DO, Mason JC and Evans PC (2009). Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State. Wolters Kluwer  Arteriosclerosis Thrombosis and Vascular Biology  vol. 29, (11) 1851-1857.  
Ali F, Zakkar M, Karu K, Lidington EA, Hamdulay SS, Boyle JJ, Zloh M, Bauer A, Haskard DO, Evans PC and Mason JC (2009). Induction of the Cytoprotective Enzyme Heme Oxygenase-1 by Statins Is Enhanced in Vascular Endothelium Exposed to Laminar Shear Stress and Impaired by Disturbed Flow*. Elsevier  Journal of Biological Chemistry  vol. 284, (28) 18882-18892.  
Evans PC (2009). Nur77. Wolters Kluwer  Circulation Research  vol. 104, (6) 707-709.  

2008

Evans PC (2008). Effects of shear stress on endothelial activation and vascular inflammation. Elsevier  Biomedicine & Pharmacotherapy  vol. 62, (8) 503-504.  
Lutz J, Luong LA, Strobl M, Deng M, Huang H, Anton M, Zakkar M, Enesa K, Chaudhury H, Haskard DO, Baumann M, Boyle J, Harten S, Maxwell PH, Pusey C, Heemann U and Evans PC (2008). The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation. Springer Nature  Journal of Molecular Medicine  vol. 86, (12) 1329-1339.  
Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong LA, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO and Evans PC (2008). Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis. Wolters Kluwer  Circulation Research  vol. 103, (7) 726-732.  
Ridger V, Krams R, Carpi A and Evans PC (2008). Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update. Elsevier  Biomedicine & Pharmacotherapy  vol. 62, (8) 536-540.  
Enesa K, Ito K, Luong LA, Thorbjornsen I, Phua C, To Y, Dean J, Haskard DO, Boyle J, Adcock I and Evans PC (2008). Hydrogen Peroxide Prolongs Nuclear Localization of NF-κB in Activated Cells by Suppressing Negative Regulatory Mechanisms*. Elsevier  Journal of Biological Chemistry  vol. 283, (27) 18582-18590.  
Birks EJ, Latif N, Enesa K, Folkvang T, Luong LA, Sarathchandra P, Khan M, Ovaa H, Terracciano CM, Barton PJR, Yacoub MH and Evans PC (2008). Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy. Oxford University Press (OUP)  Cardiovascular Research  vol. 79, (3) 472-480.  
Mason JC, Kinderlerer A, Ali F, Johns M, Leung V, Boyle J, Evans P and Haskard DO (2008). KLF‐2‐dependent, shear stress‐induced expression of CD59: a novel cytoprotective mechanism against complement‐mediated injury in the vasculature. Wiley  The FASEB Journal  vol. 22, (S1) 471.2-471.2.  
Foin N, Evans P and Krams R (2008). Atherosclerosis: cell biology and lipoproteins – new developments in imaging of inflammation of the vulnerable plaque. Wolters Kluwer  Current Opinion in Lipidology  vol. 19, (1) 98-100.  
Enesa K, Zakkar M, Chaudhury H, Luong LA, Rawlinson L, Mason JC, Haskard DO, Dean JLE and Evans PC (2008). NF-κB Suppression by the Deubiquitinating Enzyme Cezanne A NOVEL NEGATIVE FEEDBACK LOOP IN PRO-INFLAMMATORY SIGNALING*. Elsevier  Journal of Biological Chemistry  vol. 283, (11) 7036-7045.  

2007

Helderman F, Segers D, de Crom R, Hierck BP, Poelmann RE, Evans PC and Krams R (2007). Effect of shear stress on vascular inflammation and plaque development. Wolters Kluwer  Current Opinion in Lipidology  vol. 18, (5) 527-533.  
Evans KEAPC (2007). Chains of command: Ubiquitin in proinflammatory signalling. Portland Press  The Biochemist  vol. 29, (4) 24-27.  
Partridge J, Carlsen H, Enesa K, Chaudhury H, Zakkar M, Luong L, Kinderlerer A, Johns M, Blomhoff R, Mason JC, Haskard DO and Evans PC (2007). Laminar shear stress acts as a switch to regulate divergent functions of NF‐κB in endothelial cells. Wiley  The FASEB Journal  vol. 21, (13) 3553-3561.  

2006

Marques C, Guo W, Pereira P, Taylor A, Patterson C, Evans PC and Shang F (2006). The triage of damaged proteins: degradation by the ubiquitin‐proteasome pathway or repair by molecular chaperones. Wiley  The FASEB Journal  vol. 20, (6) 741-743.  

2005

Evans PC (2005). Regulation of pro-inflammatory signalling networks by ubiquitin: identification of novel targets for anti-inflammatory drugs. Cambridge University Press (CUP)  Expert Reviews in Molecular Medicine  vol. 7, (12) 1-19.  
Goodman RS, Ewing J, Evans PC, Craig J, Poulton K, Dyer PA, Marcus RE and Taylor CJ (2005). Donor CD31 genotype and its association with acute graft-versus-host disease in HLA identical sibling stem cell transplantation. Springer Nature  Bone Marrow Transplantation  vol. 36, (2) 151-156.  

2004

EVANS PC, Huib O, HAMON M, KILSHAW PJ, Svetlana H, BAUER S, PLOEGH HL and SMITH TS (2004). Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity. Portland Press  Biochemical Journal  vol. 378, (3) 727-734.  

2003

Evans PC, Smith TS, Lai M-J, Williams MG, Burke DF, Heyninck K, Kreike MM, Beyaert R, Blundell TL and Kilshaw PJ (2003). A Novel Type of Deubiquitinating Enzyme*. Elsevier  Journal of Biological Chemistry  vol. 278, (25) 23180-23186.  

2001

Evans PC, Taylor ER, Coadwell J, Heyninck K, Beyaert R and Kilshaw PJ (2001). Isolation and characterization of two novel A20-like proteins. Portland Press  Biochemical Journal  vol. 357, (Pt 3) 617-623.  
EVANS PC, TAYLOR ER, COADWELL J, HEYNINCK K, BEYAERT R and KILSHAW PJ (2001). Isolation and characterization of two novel A20-like proteins. Portland Press  Biochemical Journal  vol. 357, (3) 617-623.  
Corps E, Carter C, Karecla P, Ahrens T, Evans P and Kilshaw P (2001). Recognition of E-cadherin by Integrin αEβ7 REQUIREMENT FOR CADHERIN DIMERIZATION AND IMPLICATIONS FOR CADHERIN AND INTEGRIN FUNCTION*. Elsevier  Journal of Biological Chemistry  vol. 276, (33) 30862-30870.  
Evans PC, Smith S, Hirschfield G, Rigopoulou E, Wreghitt TG, Wight DGD, Taylor CJ and Alexander GJM (2001). Recipient HLA-DR3, tumour necrosis factor-α promoter allele-2 (tumour necrosis factor-2) and cytomegalovirus infection are inter-related risk factors for chronic rejection of liver grafts. Elsevier  Journal of Hepatology  vol. 34, (5) 711-715.  
Evans PC, Taylor ER and Kilshaw PJ (2001). SIGNALING THROUGH CD31 PROTECTS ENDOTHELIAL CELLS FROM APOPTOSIS. Wolters Kluwer  Transplantation  vol. 71, (3) 457-460.  
Buckley CD (2001). Signaling Through CD31 Protects Endothelial Cells from Apoptosis. Transplantation 2001; 71: 457. Wolters Kluwer  Transplantation  vol. 71, (3) 343-344.  

2000

Evans PC and Kilshaw PJ (2000). INTERLEUKIN-13 PROTECTS ENDOTHELIAL CELLS FROM APOPTOSIS AND ACTIVATION. Wolters Kluwer  Transplantation  vol. 70, (6) 928-934.  
Lambert NC, Evans PC, Hashizumi TL, Maloney S, Gooley T, Furst DE and Nelson JL (2000). Cutting Edge: Persistent Fetal Microchimerism in T Lymphocytes Is Associated with HLA-DQA1*0501: Implications in Autoimmunity. The American Association of Immunologists  The Journal of Immunology  vol. 164, (11) 5545-5548.  
Evans PC, Soin A, Wreghitt TG, Taylor CJ, Wight DGD and Alexander GJM (2000). AN ASSOCIATION BETWEEN CYTOMEGALOVIRUS INFECTION AND CHRONIC REJECTION AFTER LIVER TRANSPLANTATION. Wolters Kluwer  Transplantation  vol. 69, (1)  

1999

EVANS PC, GRAY JJ, WREGHITT TG, MARCUS RE and ALEXANDER GJM (1999). Comparison of three PCR techniques for detecting cytomegalovirus (CMV) DNA in serum, detection of early antigen fluorescent foci and culture for the diagnosis of CMV infection. Microbiology Society  Journal of Medical Microbiology  vol. 48, (11) 1029-1035.  
Evans PC, Coleman N, Wreghitt TG, Wight DGD and Alexander GJM (1999). Cytomegalovirus infection of bile duct epithelial cells, hepatic artery and portal venous endothelium in relation to chronic rejection of liver grafts. Elsevier  Journal of Hepatology  vol. 31, (5) 913-920.  
Nasu K, Whyte A, Green SJ, Evans PC and Kilshaw PJ (1999). α-GALACTOSYL-MEDIATED ACTIVATION OF PORCINE ENDOTHELIAL CELLS. Wolters Kluwer  Transplantation  vol. 68, (6) 861-867.  
Maloney S, Smith A, Furst DE, Myerson D, Rupert K, Evans PC and Nelson JL (1999). Microchimerism of maternal origin persists into adult life. American Society for Clinical Investigation  Journal of Clinical Investigation  vol. 104, (1) 41-47.  
Evans PC, Lambert N, Maloney S, Furst DE, Moore JM and Nelson JL (1999). Long-Term Fetal Microchimerism in Peripheral Blood Mononuclear Cell Subsets in Healthy Women and Women With Scleroderma. American Society of Hematology  Blood  vol. 93, (6) 2033-2037.  

1998

Evans PC, Soin A, Wreghitt TG and Alexander GJ (1998). Qualitative and semiquantitative polymerase chain reaction testing for cytomegalovirus DNA in serum allows prediction of CMV related disease in liver transplant recipients. BMJ  Journal of Clinical Pathology  vol. 51, (12)  
Evans PC, Gray J, Wreghitt TG and Alexander GJM (1998). Optimisation of the polymerase chain reaction and dot-blot hybridisation for detecting cytomegalovirus DNA in urine: comparison with detection of early antigen fluorescent foci and culture. Elsevier  Journal of Virological Methods  vol. 73, (1) 41-52.  
Nelson JL, Furst DE, Maloney S, Gooley T, Evans PC, Smith A, Bean MA, Ober C and Bianchi DW (1998). Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. Elsevier  The Lancet  vol. 351, (9102) 559-562.