Tissue-resident memory T cells in epicardial adipose tissue comprise transcriptionally distinct subsets that are modulated in atrial fibrillation
Vyas V, Sandhar B, Keane JM, Wood EG, Blythe H, Jones A, Shahaj E, Fanti S, Williams J, Metic N, Efremova M, Ng HL, Nageswaran G, Byrne S, Feldhahn N, Marelli-Berg F, Chain B, Tinker A, Finlay MC and Longhi MP
Nature Cardiovascular Research, Springer Nature vol. 3 (9), 1067-1082.  
23-08-2024

The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing.
Fu H, Vuononvirta J, Fanti S, Bonacina F, D’Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi M, Grevitt P, Madeeha S, Egle S, Godinho S, Bombardieri M, Smith D, Cooper D, Asif I, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD and Marelli-Berg F
, Editors: Figliuolo ML. Nature Metabolism, Nature Research 
26-10-2023

Circulating c-Met–Expressing Memory T Cells Define Cardiac Autoimmunity
Fanti S, Stephenson E, Rocha-Vieira E, Protonotarios A, Kanoni S, Shahaj E, Longhi MP, Vyas VS, Dyer C, Pontarini E, Asimaki A, Bueno-Beti C, De Gaspari M, Rizzo S, Basso C, Bombardieri M, Coe D, Wang G, Harding D, Gallagher I, Solito E, Elliott P, Heymans S, Sikking M, Savvatis K, Mohiddin SA and Marelli-Berg FM
Circulation, Wolters Kluwer vol. 146 (25), 1930-1945.  
23-11-2022

Obesity and diabetes are major risk factors for epicardial adipose tissue inflammation
Vyas V, Blythe H, Wood EG, Sandhar B, Sarker S-J, Balmforth D, Ambekar SG, Yap J, Edmondson SJ, Di Salvo C, Wong K, Roberts N, Uppal R, Adams B, Shipolini A, Oo AY, Lawrence D, Kolvekar S, Lall KS, Finlay MC and Longhi MP
Jci Insight, American Society For Clinical Investigation vol. 6 (16) 
23-08-2021

Isolation of stromal vascular fraction cell suspensions from mouse and human adipose tissues for downstream applications
Hearnden R, Sandhar B, Vyas V and Longhi MP
Star Protocols, Elsevier vol. 2 (2) 
30-03-2021

Delayed-onset myocarditis following COVID-19
Bajaj R, Sinclair HC, Patel K, Low B, Pericao A, Manisty C, Guttmann O, Zemrak F, Miller O, Longhi P, Proudfoot A, Lams B, Agarwal S, Marelli-Berg FM, Tiberi S, Cutino-Moguel T, Carr-White G and Mohiddin SA
The Lancet Respiratory Medicine, Elsevier vol. 9 (4), e32-e34.  
19-02-2021

HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids
Wood EG, Macdougall CE, Blythe H, Clément M, Colas RA, Dalli J, Marelli-Berg F and Longhi MP
Scientific Reports, Springer Nature vol. 10 (1) 
30-11-2020

Inflammation and adiposity: new frontiers in atrial fibrillation
Vyas V, Hunter RJ, Longhi MP and Finlay MC
Ep Europace, Oxford University Press (Oup) vol. 22 (11), 1609-1618.  
02-10-2020

Constitutive Activation of β-Catenin in Conventional Dendritic Cells Increases the Insulin Reserve to Ameliorate the Development of Type 2 Diabetes in Mice
Macdougall CE, Wood EG, Solomou A, Scagliotti V, Taketo MM, Gaston-Massuet C, Marelli-Berg FM, Charalambous M and Longhi MP
Diabetes, American Diabetes Association vol. 68 (7), 1473-1484.  
02-05-2019

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte J-S, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P and Marot G
Cell, Elsevier vol. 177 (5), 1201-1216.e19.  
25-04-2019

Erratum: Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR (Cell (2019) 177(5) (1201–1216.e19), (S0092867419302806), (10.1016/j.cell.2019.03.018))
Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P and Marot G
Cell vol. 178 (1), 263-263.  
25-04-2019

Adipose tissue dendritic cells in steady‐state
Macdougall CE and Longhi MP
Immunology, Wiley vol. 156 (3), 228-234.  
13-01-2019

Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation
Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P, Pellegatta F, Grigore L, Da Dalt L, Annoni A, Gregori S, Xiao Q, Caruso D, Mitro N, Catapano AL, Marelli-Berg FM and Norata GD
Nature Communications, Springer Nature vol. 9 (1) 
06-08-2018

Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets
Macdougall CE, Wood EG, Loschko J, Scagliotti V, Cassidy FC, Robinson ME, Feldhahn N, Castellano L, Voisin M-B, Marelli-Berg F, Gaston-Massuet C, Charalambous M and Longhi MP
Cell Metabolism, Elsevier vol. 27 (3), 588-601.e4.  
01-03-2018

Signatures of Inflammation and Impending Multiple Organ Dysfunction in the Hyperacute Phase of Trauma
CABRERA CP, MANSON J, SHEPHERD JM, TORRANCE HD, WATSON D, LONGHI MP, HOTI M, PATEL MB, O'DWYER M, NOURSHARGH S, PENNINGTON DJ, BARNES MR and BROHI K
Plos Medicine, Public Library of Science (Plos) 
17-07-2017

Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study.
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB, O'Dwyer M, Nourshargh S, Pennington DJ, Barnes MR and Brohi K
Plos Med vol. 14 (7) 
01-07-2017

Obesity-induced metabolic stress leads to biased effector memory CD4+ T cell differentiation via PI3K p110δ/Akt-mediated signals
MAURO C, Smith J, Cucchi D, Coe D, Fu H, Bonacina F, Baragetti A, Cermenati G, Caruso D, Mitro N, Catapano AL, Ammirati E, Longhi MP, Okkenhaug K, Norata GD and Marelli-Berg FM
Cell Metabolism, Elsevier (Cell Press) 
09-02-2017

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells.
Menezes S, Melandri D, Anselmi G, Perchet T, Loschko J, Dubrot J, Patel R, Gautier EL, Hugues S, Longhi MP, Henry JY, Quezada SA, Lauvau G, Lennon-Duménil A-M, Gutiérrez-Martínez E, Bessis A, Gomez-Perdiguero E, Jacome-Galarza CE, Garner H, Geissmann F, Golub R, Nussenzweig MC and Guermonprez P
Immunity, Elsevier Inc. vol. 45 (6), 1205-1218.  
20-12-2016

Dendritic cells and adipose tissue
Rajan SS and Longhi MP
Immunology, Wiley vol. 149 (4), 353-361.  
23-08-2016

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine
Anandasabapathy N, Feder R, Mollah S, Tse S-W, Longhi MP, Mehandru S, Matos I, Cheong C, Ruane D, Brane L, Teixeira A, Dobrin J, Mizenina O, Park CG, Meredith M, Clausen BE, Nussenzweig MC and Steinman RM
Journal of Experimental Medicine, Rockefeller University Press vol. 211 (9), 1875-1891.  
18-08-2014

Direct Type I IFN but Not MDA5/TLR3 Activation of Dendritic Cells Is Required for Maturation and Metabolic Shift to Glycolysis after Poly IC Stimulation
Pantel A, Teixeira A, Haddad E, Wood EG, Steinman RM and Longhi MP
Plos Biology, Public Library of Science (Plos) vol. 12 (1) 
01-01-2014

Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells
Barbuto S, Idoyaga J, Vila-Perelló M, Longhi MP, Breton G, Steinman RM and Muir TW
Nature Chemical Biology, Springer Nature vol. 9 (4), 250-256.  
17-02-2013

Dendritic cell‐targeted protein vaccines: a novel approach to induce T‐cell immunity
Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ and Steinman RM
Journal of Internal Medicine, Wiley vol. 271 (2), 183-192.  
04-01-2012

A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T‐cell immunity in vivo
Pantel A, Cheong C, Dandamudi D, Shrestha E, Mehandru S, Brane L, Ruane D, Teixeira A, Bozzacco L, Steinman RM and Longhi MP
European Journal of Immunology, Wiley vol. 42 (1), 101-109.  
12-12-2011

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
Cheong C, Matos I, Choi J-H, Dandamudi DB, Shrestha E, Longhi MP, Jeffrey KL, Anthony RM, Kluger C, Nchinda G, Koh H, Rodriguez A, Idoyaga J, Pack M, Velinzon K, Park CG and Steinman RM
Cell, Elsevier vol. 143 (3), 416-429.  
01-10-2010

HIV gag protein is efficiently cross‐presented when targeted with an antibody towards the DEC‐205 receptor in Flt3 ligand‐mobilized murine DC
Bozzacco L, Trumpfheller C, Huang Y, Longhi MP, Shimeliovich I, Schauer JD, Park CG and Steinman RM
European Journal of Immunology, Wiley vol. 40 (1), 36-46.  
30-12-2009

CD59 Blockade Enhances Antigen-Specific CD4+ T Cell Responses in Humans: A New Target for Cancer Immunotherapy?
Sivasankar B, Longhi MP, Gallagher KME, Betts GJ, Morgan BP, Godkin AJ and Gallimore AM
The Journal of Immunology, The American Association of Immunologists vol. 182 (9), 5203-5207.  
01-05-2009

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant.
LONGHI PM, Trumpfheller C, Idoyaga J, Caskey M, Matos I, Kluger C, Salazar AM, Colonna M and Steinman RM
J Exp Med vol. 206 (7), 1589-1602.  
01-01-2009

Interleukin-6 Is Crucial for Recall of Influenza-Specific Memory CD4+ T Cells
Longhi MP, Wright K, Lauder SN, Nowell MA, Jones GW, Godkin AJ, Jones SA and Gallimore AM
Plos Pathogens, Public Library of Science (Plos) vol. 4 (2) 
29-02-2008

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine
Trumpfheller C, Caskey M, Nchinda G, Longhi MP, Mizenina O, Huang Y, Schlesinger SJ, Colonna M and Steinman RM
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 105 (7), 2574-2579.  
19-02-2008

CD62L (L-Selectin) Down-Regulation Does Not Affect Memory T Cell Distribution but Failure to Shed Compromises Anti-Viral Immunity
Richards H, Longhi MP, Wright K, Gallimore A and Ager A
The Journal of Immunology, The American Association of Immunologists vol. 180 (1), 198-206.  
01-01-2008

CD59a deficiency exacerbates influenza‐induced lung inflammation through complement‐dependent and ‐independent mechanisms
Longhi MP, Williams A, Wise M, Morgan BP and Gallimore A
European Journal of Immunology, Wiley vol. 37 (5), 1266-1274.  
19-04-2007

CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens
Sivasankar B, Donev RM, Longhi MP, Hughes TR, Davies R, Cole DS, Morgan BP and Marchbank KJ
Molecular Immunology, Elsevier vol. 44 (11), 2978-2987.  
12-02-2007

Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity
Omidvar N, Wang ECY, Brennan P, Longhi MP, Smith RAG and Morgan BP
The Journal of Immunology, The American Association of Immunologists vol. 176 (5), 2915-2923.  
01-03-2006

Holding T cells in check – a new role for complement regulators?
Longhi MP, Harris CL, Morgan BP and Gallimore A
Trends in Immunology, Elsevier vol. 27 (2), 102-108.  
10-01-2006

Cutting Edge: Murine CD59a Modulates Antiviral CD4+ T Cell Activity in a Complement-Independent Manner
Longhi MP, Sivasankar B, Omidvar N, Morgan BP and Gallimore A
The Journal of Immunology, The American Association of Immunologists vol. 175 (11), 7098-7102.  
01-12-2005