Dr Pradeepa Madapura
Senior Lecturer
Blizard Institute
Queen Mary University of London
Queen Mary University of London
Research
Neurodevelopmental disorders, brain organoids, In vitro brain development, neuroepigenetics, functional genomics
Interests
We use human stem cell-derived cerebral organoid models to investigate the mechanism through which mutations in epigenetic regulators contribute to neurodevelopmental and cardiovascular disorders.Publications
2024
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Jayakumar S, Patel M, Boulet F, Aziz H, Brooke GN, Tummala H and Pradeepa MM
Nature Communications, Springer Nature vol. 15 (1)
07-06-2024
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Jacob DR, Guiblet WM, Mamayusupova H, Shtumpf M, Ciuta I, Ruje L, Gretton S, Bikova M, Correa C, Dellow E, Agrawal SP, Shafiei N, Drobysevskaja A, Armstrong CM, Lam JDG, Vainshtein Y, Clarkson CT, Thorn GJ, Sohn K, Pradeepa MM, Chandrasekharan S, Brooke GN, Klenova E, Zhurkin VB and Teif VB
Clinical Epigenetics, Springer Nature vol. 16 (1)
01-04-2024
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Jayakumar S, Patel M, Boulet F, Aziz H, Brooke GN, Tummala H and Pradeepa MM
Nature Communications, Springer Nature vol. 15 (1)
08-01-2024
2023
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Pal D, Patel M, Boulet F, Sundarraj J, Grant OA, Branco MR, Basu S, Santos SDM, Zabet NR, Scaffidi P and Pradeepa MM
Nature Structural & Molecular Biology, Springer Nature vol. 30 (7), 935-947.
12-06-2023
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De Vas MG, Boulet F, Joshi SS, Garstang MG, Khan TN, Atla G, Parry D, Moore D, Cebola I, Zhang S, Cui W, Lampe AK, Lam WW, Consortium GER, Ferrer J, Pradeepa MM and Atanur SS
Life Science Alliance, Life Science Alliance vol. 6 (5)
28-02-2023
2022
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Rodriguez-Algarra F, Seaborne RAE, Danson AF, Yildizoglu S, Yoshikawa H, Law PP, Ahmad Z, Maudsley VA, Brew A, Holmes N, Ochôa M, Hodgkinson A, Marzi SJ, Pradeepa MM, Loose M, Holland ML and Rakyan VK
Genome Biology, Springer Nature vol. 23 (1)
14-02-2022
2021
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Sundarraj J, Taylor GCA, von Kriegsheim A and Pradeepa MM
Wellcome Open Research, F1000research vol. 2
14-09-2021
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Olley G, Pradeepa MM, Grimes GR, Piquet S, Polo SE, FitzPatrick DR, Bickmore WA and Boumendil C
Nature Communications, Springer Nature vol. 12 (1)
25-05-2021
2019
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Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ, Wakeling E, Carroll N, Ross A, Park S-M, Bickmore WA, Pradeepa MM and FitzPatrick DR
Nature Genetics, Springer Nature vol. 51 (7), 1192-1192.
03-06-2019
2018
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Garstang MG and Pradeepa MM
Mol Cell vol. 71 (1), 3-5.
05-07-2018
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Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ, Wakeling E, Carroll N, Ross A, Park S-M, Bickmore WA, Pradeepa MM, FitzPatrick DR and Deciphering Developmental Disorders Study
Nature Genetics, Springer Nature vol. 50 (5), 767-767.
12-02-2018
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Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ, Wakeling E, Carroll N, Ross A, Park S-M, Deciphering Developmental Disorders Study , Bickmore WA, Pradeepa MM and FitzPatrick DR
Nature Genetics, Springer Nature vol. 50 (3), 329-332.
29-01-2018
2017
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Marin R, Cortez D, Lamanna F, Pradeepa MM, Leushkin E, Julien P, Liechti A, Halbert J, Brüning T, Mössinger K, Trefzer T, Conrad C, Kerver HN, Wade J, Tschopp P and Kaessmann H
Genome Research, Cold Spring Harbor Laboratory vol. 27 (12), 1974-1987.
13-11-2017
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Pradeepa MM, Taylor GCA and von Kriegsheim A
Wellcome Open Research, F1000research vol. 2
12-09-2017
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Pradeepa MM, McKenna F, Taylor GCA, Bengani H, Grimes GR, Wood AJ, Bhatia S and Bickmore WA
Plos Genetics, Public Library of Science (Plos) vol. 13 (4)
06-04-2017
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Pradeepa MM
Transcription vol. 8 (1), 40-47.
01-01-2017
2016
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Marulasiddappa P, Pradeepa MM, Kumar Y, Grimes G, Illingworth R and Bickmore W
Protocol Exchange, Springer Nature
05-05-2016
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Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GCA, Schneider R and Bickmore WA
Nature Genetics vol. 48 (6), 681-686.
18-04-2016
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Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S, Martin K, Griffiths SJ, Enright AJ, Yamamoto M, Pradeepa MM, Lennox KA, Behlke MA, Talbot S, Haas J, Dölken L, Griffiths WJ, Wang Y, Angulo A and Ghazal P
Plos Biology, Public Library of Science (Plos) vol. 14 (3)
03-03-2016
2015
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Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR and Bickmore WA
Genes & Development, Cold Spring Harbor Laboratory vol. 29 (18), 1897-1902.
15-09-2015
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Gupta N, Madapura MP, Bhat UA and Rao MRS
Journal of Biological Chemistry, Elsevier vol. 290 (19), 12101-12122.
28-03-2015
2014
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Pradeepa MM, Grimes GR, Taylor GCA, Sutherland HG and Bickmore WA
Nucleic Acids Research, Oxford University Press (Oup) vol. 42 (14), 9021-9032.
23-07-2014
2013
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Taylor GCA, Eskeland R, Hekimoglu-Balkan B, Pradeepa MM and Bickmore WA
Genome Research, Cold Spring Harbor Laboratory vol. 23 (12), 2053-2065.
29-08-2013
2012
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Pradeepa MM, Sutherland HG, Ule J, Grimes GR and Bickmore WA
Plos Genetics, Public Library of Science (Plos) vol. 8 (5)
01-01-2012
2009
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Pradeepa MM, Nikhil G, Kishore AH, Bharath GN, Kundu TK and Rao MRS
Journal of Biological Chemistry, Elsevier vol. 284 (43), 29956-29967.
26-08-2009
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Kolthur-Seetharam U, Pradeepa MM, Gupta N, Narayanaswamy R and Rao MRS
Journal of Histochemistry & Cytochemistry, Sage Publications vol. 57 (10), 951-962.
08-06-2009
2008
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Pradeepa MM, Manjunatha S, Sathish V, Agrawal S and Rao MRS
Molecular and Cellular Biology, Taylor & Francis vol. 28 (13), 4331-4341.
01-07-2008
2007
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Pradeepa MM and Rao MRS
Society of Reproduction and Fertility vol. 63, 1-10.
01-01-2007
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Dhar S, Pradeepa MM and Rao MRS
Proceedings of The National Academy of Sciences India Section B-Biological Sciences vol. 77, 61-71.
01-01-2007
Grants
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Pradeepa Madapura
£759,321 MRC Medical Research Council
01-11-2023 - 31-10-2026
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Pradeepa Madapura and Nicolae Radu Zabet
£205,822 Barts and the London Charity
01-04-2023 - 31-03-2027
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Pradeepa Madapura
£179,947 EU Commission - Horizon 2020
05-01-2021 - 18-01-2023
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Pradeepa Madapura
£821,014 MRC Medical Research Council
01-02-2020 - 31-10-2023
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Pradeepa Madapura
£40,000 Barts and the London Charity
01-09-2019 - 31-08-2021