Dr Wenhao Li

Wenhao Li

Clinical Lecturer in Hepatology

Blizard Institute

Research

Metabolic dysfunction associated steatotic liver disease, type 2 diabetes, gut-adipose-liver axis, liver immunology

Interests

Have expertise in in vitro models of liver cell injury (2D, spheroids). Would like to use organ on a chip to interrogate gut-adipose-liver axis in the pathogenesis of steatotic liver disease using human cells.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2024

Perez-Ternero C, Li W, Aubdool AA, Goldin RD, Loy J, Devalia K, Alazawi W and Hobbs AJ (2024). Endogenous C-type natriuretic peptide offsets the pathogenesis of steatohepatitis, hepatic fibrosis and portal hypertension. Oxford University Press (OUP)  PNAS Nexus   
Li W, Brennan PN and Tavabie OD (2024). Letter to the Editor: Future-proofing transplant hepatology training: Shared learnings from “across the pond”. Wolters Kluwer  Liver Transplantation  vol. 31, (1) e1-e2.  
Chambers ES, Cai W, Vivaldi G, Jolliffe DA, Perdek N, Li W, Faustini SE, Gibbons JM, Pade C, Richter AG, Coussens AK and Martineau AR (2024). Influence of individuals’ determinants including vaccine type on cellular and humoral responses to SARS-CoV-2 vaccination. Springer Nature  npj Vaccines  vol. 9, (1)  
Brennan PN, Tavabie OD, Li W, Marjot T, Corless L, Fallowfield JA, Jarvis H, Mansour D, McPherson S, Rosenberg W, Rockell K, Tomlinson J, Yeoman A, Tsochatzis EA, Dillon JF, Alazawi W and Abeysekera KWM (2024). Progress is impossible without change: understanding the evolving nomenclature of steatotic liver disease and its effect on hepatology practice. Elsevier  The Lancet Gastroenterology & Hepatology  vol. 9, (6) 577-582.  

2023

Li W, Sheridan D, McPherson S, Alazawi W, Abeysekera K, Marjot T, Brennan P, Mahgoub S, Cacciottolo T, Hydes T, Hardy T, McGinty G, Tavabie O, Cathcart J, Premathilaka C, Mukhopadhya A, Bhat A, Begum S, Abushaban B, Bhuva M, Sinclair S, Leith D, McCulloch C, Leithead J, Fox R, Shah MH, Campbell E, Brown E, Mansour D and Shah F (2023). National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022. Elsevier  JHEP Reports  vol. 5, (12)  
Cheung DYT, Chan HCH, Conway M, Wong CKH, Li WHC, Wang MP and Lam TH (2023). WhatsApp group discussion for smoking relapse prevention: a randomised controlled trial (abridged secondary publication). Hong Kong Medical Journal  vol. 29 Suppl 3, (3) 16-18.  
Li W, Sheridan D, Mcpherson S and Alazawi W (2023). THU-447 The national audit of non-alcoholic fatty liver disease (NAFLD) identifies variations and shortfalls in delivery of care in the UK. Elsevier  Journal of Hepatology  vol. 78,  
Li W, Garrido P, Mir IG, Waller K, Jong AV-D, Brindley JH, Khan W, Hood G, Boot J, Mein C, Devalia K, Loy J and Alazawi W (2023). WED-406 Toll-like receptor 5 signalling mediates pro-inflammatory and fibrogenic responses in non-alcoholic steatohepatitis (NASH). Elsevier  Journal of Hepatology  vol. 78,  
UK TTCFRAAIH, Tavabie OD, Abeysekera KW, Brennan PN, Marjot T, Kronsten VT, Li W, Nayagam JS, Dhaliwal A, Hardy T, Maurice JB, Zakeri N, Abbas N, Abbasi A, Abbott J, Abdul R, Abdulaziz M, Abduljabbar D, Adamson R, Adebayo D, Adhikarla AK, Adler M, Afifi M, Ahmad S, Ahmed S, Aithal G, Akram A, Al Radhi B, Al-Talib I and Alele J (2023). Regional variation in characteristics of patients with decompensated cirrhosis admitted to hospitals in the UK. Elsevier  The Lancet Gastroenterology & Hepatology  vol. 8, (7) 604-606.  
Chung JOK, Li WHC, Chan GCF, Chiu SY and Ho KY (2023). Psychometric evaluation of the Chinese version of the Resilience Scale for Children: abridged secondary publication. Hong Kong Medical Journal  vol. 29 Suppl 2, (1) 12-14.  
Li W, Abbas N, Brennan PN, Mcdowell H, Navaratnam J, Phoolchund A, Scott R, Shearer J, White H and Tavabie OD (2023). UK national trainee survey of hepatology training, research and the future workforce. Frontline Gastroenterology  vol. 14, (4) 326-333.  
Wells G, Spiers J, Williams FR, Li W, Tavabie OD and Brennan PN (2023). An overview of the challenges and key initiatives in hepatology practice in the UK in 2022: a cautionary tale, but reasons for optimism - British Association for the Study of the Liver (BASL) Annual Meeting 2022 Conference Report. Clinical Medicine  vol. 23, (1) 73-75.  

2022

Waller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C and Alazawi W (2022). Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease. The Korean Association for the Study of the Liver  Clinical and Molecular Hepatology  vol. 29, (2) 417-432.  
Jolliffe DA, Vivaldi G, Chambers ES, Cai W, Li W, Faustini SE, Gibbons JM, Pade C, Coussens AK, Richter AG, McKnight Á and Martineau AR (2022). Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled Trial. MDPI  Nutrients  vol. 14, (18)  
Vivaldi G, Jolliffe DA, Faustini S, Shields AM, Holt H, Perdek N, Talaei M, Tydeman F, Chambers ES, Cai W, Li W, Gibbons JM, Pade C, McKnight Á, Shaheen SO, Richter AG and Martineau AR (2022). Correlation Between Postvaccination Anti-Spike Antibody Titers and Protection Against Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Population-Based Longitudinal Study. Oxford University Press (OUP)  The Journal of Infectious Diseases  vol. 226, (11) 1903-1908.  
Spiers J, Brindley JH, Li W and Alazawi W (2022). What’s new in non-alcoholic fatty liver disease? BMJ  Frontline Gastroenterology  vol. 13, (e1) e102-e108.  
McPherson S, Armstrong MJ, Cobbold JF, Corless L, Anstee QM, Aspinall RJ, Barclay ST, Brennan PN, Cacciottolo TM, Goldin RD, Hallsworth K, Hebditch V, Jack K, Jarvis H, Johnson J, Li W, Mansour D, McCallum M, Mukhopadhya A, Parker R, Ross V, Rowe IA, Srivastava A, Thiagarajan P, Thompson AI, Tomlinson J, Tsochatzis EA, Yeoman A and Alazawi W (2022). Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group. Elsevier  The Lancet Gastroenterology & Hepatology  vol. 7, (8) 755-769.  
Li W, Kadler BK, Brindley JH, Hood G, Devalia K, Loy J, Syn W-K and Alazawi W (2022). The contribution of daytime sleepiness to impaired quality of life in NAFLD in an ethnically diverse population. Springer Nature  Scientific Reports  vol. 12, (1)  
Kavanagh E, Fernandes L, Li W, Roycroft M and FitzPatrick M (2022). Physician trainee research collaboratives: a mixed methods exploration of UK experience. Elsevier  Clinical Medicine  vol. 22, (2) 119-124.  
Usai C, Gibbons JM, Pade C, Li W, Jacobs SRM, McKnight Á, Kennedy PTF and Gill US (2022). The β-NGF/TrkA Signalling Pathway Is Associated With the Production of Anti-Nucleoprotein IgG in Convalescent COVID-19. Frontiers  Frontiers in Immunology  vol. 12,  
Li W, Ng CH, Quek J, Chan KE, Tan C, Zeng RW, Yong JN, Tay H, Tan DJH, Lim WH, Chee D, Ho J, Chew NWS, Mak LY, Siddiqui MS, Sanyal A, Alazawi W, Alkouri N, Muthiah M and Noureddin M (2022). The growing prevalence of nonalcoholic fatty liver disease (NAFLD), determined by fatty liver index, amongst young adults in the United States. A 20-year experience. OAE Publishing  Metabolism and Target Organ Damage  vol. 2, (4) null-null.  

2021

Luo YH, Li WHC, Cheung AT, Ho LLK, Xia W, He XL, Zhang JP and Chung JOK (2021). Relationships between resilience and quality of life in parents of children with cancer. SAGE Publications  Journal of Health Psychology  vol. 27, (5) 1048-1056.  
Cheung AT, Li WHC, Ho LLK, Ho KY, Chan GCF and Chung JOK (2021). Physical activity for pediatric cancer survivors: a systematic review of randomized controlled trials. Springer Nature  Journal of Cancer Survivorship  vol. 15, (6) 876-889.  

2020

Weng X, Luk TT, Lau OS, Suen YN, Lee JJ, Li WH-C, Kwok JYY, Lam TH and Wang MP (2020). Brief mindfulness training for smoking cessation in Chinese women in workplaces: A pilot randomized controlled trial. Elsevier  Addictive Behaviors  vol. 113,  
Li W and Alazawi W (2020). Non-alcoholic fatty liver disease. Elsevier  Clinical Medicine  vol. 20, (5) 509-512.  
Li W, Kemos P, Salciccioli JD, Marshall DC, Shalhoub J and Alazawi W (2020). Socioeconomic Factors Associated With Liver-Related Mortality From 1985 to 2015 in 36 Developed Countries. Elsevier  Clinical Gastroenterology and Hepatology  vol. 19, (8) 1698-1707.e13.  
Cheung YTD, Chan CHH, Ho KS, Tang C, Lau CWH, Li WHC, Wang MP and Lam TH (2020). Effectiveness of nicotine replacement therapy sample at outdoor smoking hotspots for initiating quit attempts and use of smoking cessation services: a protocol for a cluster randomised controlled trial. BMJ  BMJ Open  vol. 10, (4)  

2019

Li W, Homer K, Hull S, Boomla K, Robson J and Alazawi W (2019). Obesity Predicts Liver Function Testing and Abnormal Liver Results. Wiley  Obesity  vol. 28, (1) 132-138.  
Wang MP, Luk TT, Wu Y, Li WH, Cheung DY, Kwong AC, Lai V, Chan SS and Lam TH (2019). Chat-based instant messaging support integrated with brief interventions for smoking cessation: a community-based, pragmatic, cluster-randomised controlled trial. Elsevier  The Lancet Digital Health  vol. 1, (4) e183-e192.  

2018

Chung J, Lam K, Ho K, Cheung A, Ho L, Gibson F and Li W (2018). Relationships among resilience, self-esteem, and depressive symptoms in Chinese adolescents. SAGE Publications  Journal of Health Psychology  vol. 25, (13-14) 2396-2405.  
Zhao Y, Kuan HK, Chung JOK, Chan CKY and Li WHC (2018). Students' approaches to learning in a clinical practicum: A psychometric evaluation based on item response theory. Elsevier  Nurse Education Today  vol. 66, 179-186.  
Li W and Chattree A (2018). Small-Bowel Obstruction Due to Strongyloides stercoralis Infection. Elsevier  Clinical Gastroenterology and Hepatology  vol. 17, (6) a41-a42.  
Ho KY, Li WHC, Wang MP, Lam KKW, Lam TH and Chan SSC (2018). Comparison of two approaches in achieving smoking abstinence among patients in an outpatient clinic: A Phase 2 randomized controlled trial. Elsevier  Patient Education and Counseling  vol. 101, (5) 885-893.  
Wu SY-D, Wang MP, Li WH, Kwong AC, Lai VW and Lam TH (2018). Does Electronic Cigarette Use Predict Abstinence from Conventional Cigarettes among Smokers in Hong Kong? MDPI  International Journal of Environmental Research and Public Health  vol. 15, (3)  

2017

Wang M-P, Suen Y-N, Wong BY-M, Li WH-C, Koh DS-Q, Lam T-H and Chan SS-C (2017). Paternal smoking and maternal protective behaviors at home on infant’s saliva cotinine levels. Springer Nature  Pediatric Research  vol. 83, (5) 936-942.  
Wang MP, Suen YN, Li WH-C, Lam CO-B, Wu SY-D, Kwong AC-S, Lai VW, Chan SS and Lam TH (2017). Intervention With Brief Cessation Advice Plus Active Referral for Proactively Recruited Community Smokers: A Pragmatic Cluster Randomized Clinical Trial. American Medical Association (AMA)  JAMA Internal Medicine  vol. 177, (12) 1790-1797.  
De Silva S, Li W, Kemos P, Brindley JH, Mecci J, Samsuddin S, Chin-Aleong J, Feakins RM, Foster GR, Syn W-K and Alazawi W (2017). Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent. BMJ  Frontline Gastroenterology  vol. 9, (2)  
Lam TH, Li WH, Wang MP, Cheung YT, Cheung DY, Ho KY, Tan KC and Chan SS (2017). A brief, tailored smoking cessation intervention for smokers with diabetes mellitus in Hong Kong. Hong Kong Medical Journal  vol. 23 Suppl 2, (3) 10-11.  
Wang MP, Li WH, Wu Y, Lam TH and Chan SS (2017). Electronic cigarette use is not associated with quitting of conventional cigarettes in youth smokers. Springer Nature  Pediatric Research  vol. 82, (1) 14-18.  
Li W, Kotha S and Joshi D (2017). Upper Gastrointestinal Bleeding Caused by Hereditary Hemorrhagic Telangectasia. Elsevier  Clinical Gastroenterology and Hepatology  vol. 15, (7) a25-a26.  
Wang MP, Li WH, Cheung YT, Lam OB, Wu Y, Kwong AC, Lai VW, Chan SS and Lam TH (2017). Brief Advice on Smoking Reduction Versus Abrupt Quitting for Smoking Cessation in Chinese Smokers: A Cluster Randomized Controlled Trial. Oxford University Press (OUP)  Nicotine & Tobacco Research  vol. 20, (1) 67-72.  
Li WHC, Chan SSC, Wang MP, Ho KY, Cheung YTY, Chan VWF and Lam TH (2017). An Evaluation of the Youth Quitline Service Young Hong Kong Smokers. Elsevier  Journal of Adolescent Health  vol. 60, (5) 584-591.  

2016

Jackson D, Hutchinson M, Barnason S, Li W, Mannix J, Neville S, Piper D, Power T, Smith GD and Usher K (2016). Towards international consensus on patient harm: perspectives on pressure injury policy. Hindawi  Journal of Nursing Management  vol. 24, (7) 902-914.  
Coffey A, McCarthy G, Weathers E, Friedman MI, Gallo K, Ehrenfeld M, Chan S, Li WHC, Poletti P, Zanotti R, Molloy DW, McGlade C, Fitzpatrick JJ and Itzhaki M (2016). Nurses' knowledge of advance directives and perceived confidence in end‐of‐life care: a cross‐sectional study in five countries. Wiley  International Journal of Nursing Practice  vol. 22, (3) 247-257.  

2015

Li WHC, Chan SSC, Wang KMP and Lam TH (2015). Helping cancer patients quit smoking by increasing their risk perception: a study protocol of a cluster randomized controlled trial. Springer Nature  BMC Cancer  vol. 15, (1)  

2014

Li WHC, Chan SSC, Wong EML, Kwok MC and Lee ITL (2014). Effect of therapeutic play on pre- and post-operative anxiety and emotional responses in Hong Kong Chinese children: a randomised controlled trial. Hong Kong Medical Journal  vol. 20 Suppl 7, 36-39.  

2013

Coffey A, McCarthy G, Weathers E, Friedman MI, Gallo K, Ehrenfeld M, Itzhaki M, Chan S, Li WHC, Poletti P, Zanotti R, Molloy DW, McGlade C and Fitzpatrick JJ (2013). Nurses' preferred end‐of‐life treatment choices in five countries. Wiley  International Nursing Review  vol. 60, (3) 313-319.  

2012

Li WH, Chung JO and Ho EK (2012). Effectiveness of an adventure-based training programme in promoting the psychological well-being of primary schoolchildren. SAGE Publications  Journal of Health Psychology  vol. 18, (11) 1478-1492.  
Li WHC (2012). The impact of cancer on the psychosocial well-being and quality of life of Hong Kong Chinese children. Pediatric Cancer  
Li WHC (2012). Developing and evaluating an empowerment programme in promoting the psychosocial well-being and quality of life of childhood cancer survivors: A pilot study. Pediatric Cancer  
Li WHC (2012). The psychosocial well-being and quality of life of childhood cancer survivors: An exploratory study. Pediatric Cancer  
Li WHC (2012). Understanding how children coped with cancer: An essential prerequisite for designing appropriate psycho-educational interventions. Pediatric Cancer  
Li WHC (2012). Effectiveness of therapeutic play intervention in promoting the psychosocial well-being of children hospitalized with cancer. Pediatric Cancer  
Li WH, Mak YW, Chan SS, Chu AK, Lee EY and Lam T (2012). Effectiveness of a play-integrated primary one preparatory programme to enhance a smooth transition for children. SAGE Publications  Journal of Health Psychology  vol. 18, (1) 10-25.  
Li W (2012). Pediatric Cancer. 
Li W (2012). Preface. Pediatric Cancer   

2011

Li WH, Chung JO and Ho EK (2011). The effectiveness of therapeutic play, using virtual reality computer games, in promoting the psychological well‐being of children hospitalised with cancer. Wiley  Journal of Clinical Nursing  vol. 20, (15‐16) 2135-2143.  

2010

Li WHC (2010). Building up competence for student nurses in clinical ethical decisionmaking. Advances in Medicine and Biology  
Li WHC (2010). Barriers to evidence-based practice: Baccalaureate nursing student’s perspective. Advances in Medicine and Biology  

2009

Li WH and Chung OK (2009). Enhancing the efficacy of psychoeducational interventions for paediatric patients in a randomised controlled trial: methodological considerations. Wiley  Journal of Clinical Nursing  vol. 18, (21) 3013-3021.  
Li WH, Chung JO, Chui MM and Chan PS (2009). Factorial structure of the Chinese version of the 12‐item General Health Questionnaire in adolescents. Wiley  Journal of Clinical Nursing  vol. 18, (23) 3253-3261.