Dr Weiqi Li

Weiqi Li
School of Engineering and Materials Science/Institute of Bioengi
Queen Mary University of London

Research

The endothelial glycocalyx, Actin cytoskeleton, Junctional complex, Cell mechanics, Directional cell migration, Angiogenesis

Interests

My research interest lies in the mechano-regulation of the endothelial glycocalyx in vitro, particularly looking into the interplay with the cytoskeletal system and junctional complex, with the use of super-resolution microscopy, confocal microscopy and atomic force microscopy.

Publications

solid heart iconPublications of specific relevance to Predictive in vitro Models

2023

Yang Y, Guan S, Ou Z, Li W, Yan L and Situ B (2023). Advances in AIā€based cancer cytopathology. Wiley  Interdisciplinary Medicine  vol. 1, (3)  

2021

Li W and Wang W (2021). The role of actomyosin in the regulation of syndecan-1 in hyperosmosis. Elsevier  BBA - General Subjects  vol. 1865, (10)  
Pang X, Li W, Chang L, Gautrot JE, Wang W and Azevedo HS (2021). Hyaluronan (HA) Immobilized on Surfaces via Self-Assembled Monolayers of HA-Binding Peptide Modulates Endothelial Cell Spreading and Migration through Focal Adhesion. American Chemical Society  ACS Applied Materials and Interfaces  vol. 13, (22) 25792-25804.  

2020

Wu Y, Wang W, Mata A, Pugno N, Azevedo H, Karabasov S and Titirici M-M (2020). Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices. Nature Research (part of Springer Nature)  Nature Communications   

2019

Li W and Wang W (2019). Membrane tension regulates syndecan-1 expression through actin remodelling. Biochim Biophys Acta Gen Subj  vol. 1863, (11) 129413-129413.  
Pang X, Li W, Landwehr E, Yuan Y, Wang W and Azevedo HS (2019). Mimicking the endothelial glycocalyx through the supramolecular presentation of hyaluronan on patterned surfaces. Faraday Discuss   

2018

Xu J, Nyga A, Li W, Zhang X, Gavara N, Knight MM and Shelton JC (2018). Cobalt ions stimulate a fibrotic response through matrix remodelling, fibroblast contraction and release of pro-fibrotic signals from macrophages. European Cells and Materials  vol. 36, 142-155.  

2017

Li W and Wang W (2017). Structural alteration of the endothelial glycocalyx: contribution of the actin cytoskeleton. Biomech Model Mechanobiol   

2015

Stachewicz U, Qiao T, Rawlinson SCF, Almeida FV, Li W-Q, Cattell M and Barber AH (2015). 3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration. Elsevier/Science Direct  Acta Biomaterialia  vol. 27, 88-100.  

2014

Lu$y.lu@derby.ac.uk$School of Engineering and Technology Y, University of Derby , Derby , Science UW-QLSOEAM, Mary , University of London , London , Oraifige$School of Engineering and Technology UI and Science UWWSOEAM (2014). Converging Parallel Plate Flow Chambers for Studies on the Effect of the Spatial Gradient of Wall Shear Stress on Endothelial Cells. Scientific Research Publishing  Journal of Biosciences and Medicines  vol. 02, (02) 50-56.