Prof Yi Sui
Professor of Fluid Mechanics
School of Engineering and Materials Science
Queen Mary University of London
Queen Mary University of London
Research
computational modelling of cell dynamics in flows, microfluidics cell sorting and characterisation, real-time AI algorithms, in-vitro models for drug delivery
Interests
I am interested in sorting cells from patient blood that can be used to build complex in-vitro models. I have expertise in computational modelling of flow and mass transport, and AI-image based ultrahigh-throughput mechanical characterisation and label-free cell sorting. I am interested in using these tools to understand and develop microfluidics-based in-vitro models such as organ-chips.Publications of specific relevance to Predictive in vitro Models
2023
Chen S, Cheng Y, Zhao Z, Zhang K, Hao T, Sui Y, Wang W, Zhao J and Li Y (2023). Core–Shell-Structured Electrorheological Fluid with a Polarizability-Tunable Nanocarbon Shell for Enhanced Stimuli-Responsive Activity. American Chemical Society (ACS) ACS Applied Materials & Interfaces vol. 15, (29) 35741-35749. Lu RX, Guo ZY, Yu P and Sui Y (2023). Transient deformation of a viscoelastic capsule in a cross-slot microchannel: effects of inertia and membrane viscosity. Cambridge University Press (CUP) Journal of Fluid Mechanics vol. 962, Guo Z, Lin T, Jing D, Wang W and Sui Y (2023). A method for real-time mechanical characterisation of microcapsules. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1209-1220. Wang Z, Lu R, Wang W, Tian FB, Feng JJ and Sui Y (2023). A computational model for the transit of a cancer cell through a constricted microchannel. Springer Nature Biomechanics and Modeling in Mechanobiology vol. 22, (4) 1129-1143. 2022
Sun C, Dong Y, Wei J, Cai M, Liang D, Fu Y, Zhou Y, Sui Y, Wu F, Mikhaylov R, Wang H, Fan F, Xie Z, Stringer M, Yang Z, Wu Z, Tian L and Yang X (2022). Acoustically accelerated neural differentiation of human embryonic stem cells. Elsevier Acta Biomaterialia vol. 151, 333-345. Shen Y, Kang F, Cheng Y, Zhang K and Sui Y (2022). Numerical and theoretical analysis of fast evaporating sessile droplets with coupled fields. Elsevier International Journal of Thermal Sciences vol. 172, T. Lin TL, Z. Wang ZW, R. X. Lu RXL, W. Wang WW and Y. Sui YS (2022). Characterising Mechanical Properties of Flowing Microcapsules Using a Deep Convolutional Neural Network. Global Science Press Advances in Applied Mathematics and Mechanics vol. 14, (1) 79-100. 2021
Lu RX, Wang Z, Salsac A-V, Barthès-Biesel D, Wang W and Sui Y (2021). Path selection of a train of spherical capsules in a branched microchannel. Cambridge University Press (CUP) Journal of Fluid Mechanics vol. 923, Lin T, Wang Z, Lu R, Wang W and Sui Y (2021). A high-throughput method to characterize membrane viscosity of flowing microcapsules. AIP Publishing Physics of Fluids vol. 33, (1) Lin T, Wang Z, Wang W and Sui Y (2021). A neural network-based algorithm for high-throughput characterisation of viscoelastic properties of flowing microcapsules. Royal Society of Chemistry (RSC) Soft Matter vol. 17, (15) 4027-4039. 2020
Ma J, Wang Z, Young J, Lai JCS, Sui Y and Tian FB (2020). An immersed boundary-lattice Boltzmann method for fluid-structure interaction problems involving viscoelastic fluids and complex geometries. Elsevier Journal of Computational Physics vol. 415, 2019
Wang F, Contò FP, Naz N, Castrejón-Pita JR, Castrejón-Pita AA, Bailey CG, Wang W, Feng JJ and Sui Y (2019). A fate-alternating transitional regime in contracting liquid filaments. Journal of Fluid Mechanics vol. 860, 640-653. Wang Z, Sui Y, Wang W, Barthѐs-Biesel D and Salsac A-V (2019). Path Selection of a Spherical Capsule in a Branched Channel. Tech Science Press Molecular & Cellular Biomechanics vol. 16, (S2) 42-43. 2018
Wang Z, Sui Y, Salsac AV, Barthès-Biesel D and Wang W (2018). Path selection of a spherical capsule in a microfluidic branched channel: Towards the design of an enrichment device. Journal of Fluid Mechanics vol. 849, 136-162. 2017
Xu Y-Q, Jiang Y-Q, Wu J, Sui Y and Tian F-B (2017). Benchmark numerical solutions for two-dimensional fluid–structure interaction involving large displacements with the deforming-spatial-domain/stabilized space–time and immersed boundary–lattice Boltzmann methods. SAGE Publications Proceedings of the Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science vol. 232, (14) 2500-2514. 2016
Wang Z, Sui Y, Salsac AV, Barthès-Biesel D and Wang W (2016). Motion of a spherical capsule in branched tube flow with finite inertia. Journal of Fluid Mechanics vol. 806, 603-626. Tian F-B, Wang W, Wu J and Sui Y (2016). Swimming performance and vorticity structures of a mother-calf pair of fish. COMPUTERS & FLUIDS vol. 124, 1-11. Grants of specific relevance to Predictive in vitro Models
(EPSRC CDT 2023) Next Generation Organ-on-a-Chip TechnologiesHazel Screen, Martin Knight, Thomas Iskratsch, Caroline Roney, Yi Sui, David Lee, Julia Shelton, Tsz Ho Tse, John Connelly, Adrian Biddle and Lucy Norling
£7,066,811 EPSRC Engineering and Physical Sciences Research Council (01-07-2024 - 30-09-2032)